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The map label for this gene is fliI

Identifier: 189025635

GI number: 189025635

Start: 428215

End: 429558

Strand: Direct

Name: fliI

Synonym: TPASS_0402

Alternate gene names: 189025635

Gene position: 428215-429558 (Clockwise)

Preceding gene: 189025634

Following gene: 189025636

Centisome position: 37.58

GC content: 55.36

Gene sequence:

>1344_bases
ATGGAAGCAGACCTGTTGTGCAAGTATGAGGTGGCGCTCCGCGAGAGTGAGCCGGTAAAGTACGTTGGGCATGTGACAGC
AGTGAGGGGTTTATTGATTGAAAGTCGTGGCCCTCACGCGGTAGTTGGTGAATTGTGTCGGATTGTGTTGCGCCGCCAGG
GGCGACCGTTGATAGCAGAGGTAGTAGGACTTGCAGGATCGACGGTAAAACTGATGAGCTACACCGATACGCACGGGGTT
GAAGTTGGCTGTGCGGTGGTAGCAGAAGGGGCGGCACTTTCAGTCCCCGTAGGAGATGCTTTACTCGGACGCGTTTTGAA
CGCGTTTGGGAAGGCAATTGACGGGAAGGGGGAGATATATGCGCCGCTCCGCTCCGAGGTGTTGCGCGCGTCTTCTAATC
CTATGGAGCGTCTTCCGATTACGCGTCAAATGGTAACAGGAGTGCGGGTGCTTGATTCGTTGCTGGCAGTTGGTTGCGGA
CAACGTCTGGGTATTTTTTCCGGTTCGGGGGTTGGGAAGTCGACGCTGATGGGGATGATCGCGCGCAATACAGACGCAGA
TGTGTCGGTCATTGCCCTTATCGGGGAGCGTGGCCGTGAAGTGATGGATTTTGTTGCGCATGATTTGGGTCCTGAGGGTT
TGAAGCGCTCGGTAATAGTTAGTGCGACGTCTGATGAAAGTCCGCTTGCGCGGGTACGAGGTGCGTACACGGCGACAGCG
ATTGCAGAGTACTTTCGGGATCAAGGCAAACAGGTGCTGCTGCTGTTTGATTCTCTGACGCGCTTTGCAAAAGCTCAGCG
TGAGATTGGGTTAGCGTCGGGGGAGCTCCCTGCAACGCGTGGATATACCCCGGGGGTATTCGAAACGTTACCGAAACTGC
TTGAGCGTGCAGGTTCTTTTTCCATGGGGAGCGTCACCGCTTTTTATACTGTTTTGGTAGATGGGGACGATCTCGATGAG
CCGATATCAGACGCCGTGCGTGGAATTGTAGACGGGCACATTGTACTCAGTCGCGCGCTTGCGCAGCGCAATCACTATCC
TGCAATAGACGTGTTGCAAAGCGTTTCTCGCTTGGCGCACCGCGTGCTGGGTGCAGACATGAAAGAGGCAGTGCGCATAG
TGCGTCGTGCGCTTGCAGTGTACGCAGAAGTAGAGGATTTGGTACGAGTTGGTGCGTACCAGCAGGGGAGTGATGCAGAA
CTTGATCGAGCTATTGCGATGCGCGCAGAGCTTGAACGGTTCCTAACGCAAGGAGCCCAGGAGCGCGTGCGTTTTCAGGA
TACTGTAACGTCGCTGTCCATGCTGACAGGGCTCAGTATAGCACAGCCGCCTTCGGGTGTGTGA

Upstream 100 bases:

>100_bases
TGAGCTTGAGCAGCGTGTTTTGGAAGTTGCCCCCATTGTAGTGTCATCAATGTCAGCATCTAAGGGTTCTTGATAGAGAA
AGAGGCGTGGGTGTGCGTGT

Downstream 100 bases:

>100_bases
ATCTGCAAGAGCAGAGGAGATAGCGCGTGTGAAAAGGTTTTGTTTTTCTCTTGAGCGTGTGCGACGCTTGAGAGCGTTTC
GTGTACGCGAGCTGGAAGTT

Product: flagellum-specific ATP synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MEADLLCKYEVALRESEPVKYVGHVTAVRGLLIESRGPHAVVGELCRIVLRRQGRPLIAEVVGLAGSTVKLMSYTDTHGV
EVGCAVVAEGAALSVPVGDALLGRVLNAFGKAIDGKGEIYAPLRSEVLRASSNPMERLPITRQMVTGVRVLDSLLAVGCG
QRLGIFSGSGVGKSTLMGMIARNTDADVSVIALIGERGREVMDFVAHDLGPEGLKRSVIVSATSDESPLARVRGAYTATA
IAEYFRDQGKQVLLLFDSLTRFAKAQREIGLASGELPATRGYTPGVFETLPKLLERAGSFSMGSVTAFYTVLVDGDDLDE
PISDAVRGIVDGHIVLSRALAQRNHYPAIDVLQSVSRLAHRVLGADMKEAVRIVRRALAVYAEVEDLVRVGAYQQGSDAE
LDRAIAMRAELERFLTQGAQERVRFQDTVTSLSMLTGLSIAQPPSGV

Sequences:

>Translated_447_residues
MEADLLCKYEVALRESEPVKYVGHVTAVRGLLIESRGPHAVVGELCRIVLRRQGRPLIAEVVGLAGSTVKLMSYTDTHGV
EVGCAVVAEGAALSVPVGDALLGRVLNAFGKAIDGKGEIYAPLRSEVLRASSNPMERLPITRQMVTGVRVLDSLLAVGCG
QRLGIFSGSGVGKSTLMGMIARNTDADVSVIALIGERGREVMDFVAHDLGPEGLKRSVIVSATSDESPLARVRGAYTATA
IAEYFRDQGKQVLLLFDSLTRFAKAQREIGLASGELPATRGYTPGVFETLPKLLERAGSFSMGSVTAFYTVLVDGDDLDE
PISDAVRGIVDGHIVLSRALAQRNHYPAIDVLQSVSRLAHRVLGADMKEAVRIVRRALAVYAEVEDLVRVGAYQQGSDAE
LDRAIAMRAELERFLTQGAQERVRFQDTVTSLSMLTGLSIAQPPSGV
>Mature_447_residues
MEADLLCKYEVALRESEPVKYVGHVTAVRGLLIESRGPHAVVGELCRIVLRRQGRPLIAEVVGLAGSTVKLMSYTDTHGV
EVGCAVVAEGAALSVPVGDALLGRVLNAFGKAIDGKGEIYAPLRSEVLRASSNPMERLPITRQMVTGVRVLDSLLAVGCG
QRLGIFSGSGVGKSTLMGMIARNTDADVSVIALIGERGREVMDFVAHDLGPEGLKRSVIVSATSDESPLARVRGAYTATA
IAEYFRDQGKQVLLLFDSLTRFAKAQREIGLASGELPATRGYTPGVFETLPKLLERAGSFSMGSVTAFYTVLVDGDDLDE
PISDAVRGIVDGHIVLSRALAQRNHYPAIDVLQSVSRLAHRVLGADMKEAVRIVRRALAVYAEVEDLVRVGAYQQGSDAE
LDRAIAMRAELERFLTQGAQERVRFQDTVTSLSMLTGLSIAQPPSGV

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=391, Percent_Identity=33.2480818414322, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI50345984, Length=372, Percent_Identity=31.1827956989247, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4757810, Length=372, Percent_Identity=31.1827956989247, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI19913424, Length=326, Percent_Identity=31.5950920245399, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI19913428, Length=389, Percent_Identity=26.2210796915167, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI19913426, Length=398, Percent_Identity=26.1306532663317, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788251, Length=440, Percent_Identity=46.3636363636364, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1790170, Length=403, Percent_Identity=32.5062034739454, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1790172, Length=329, Percent_Identity=30.6990881458967, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790217, Length=247, Percent_Identity=28.3400809716599, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25144756, Length=409, Percent_Identity=31.0513447432763, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71988063, Length=352, Percent_Identity=32.9545454545455, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71988080, Length=374, Percent_Identity=31.8181818181818, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17565854, Length=347, Percent_Identity=30.5475504322767, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71988074, Length=445, Percent_Identity=29.2134831460674, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=401, Percent_Identity=25.6857855361596, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=365, Percent_Identity=25.2054794520548, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=444, Percent_Identity=31.5315315315315, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319370, Length=327, Percent_Identity=32.7217125382263, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6319603, Length=408, Percent_Identity=26.4705882352941, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6320016, Length=224, Percent_Identity=32.1428571428571, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI28574560, Length=451, Percent_Identity=31.7073170731707, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI24638766, Length=370, Percent_Identity=32.1621621621622, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24658560, Length=383, Percent_Identity=32.1148825065274, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24583988, Length=349, Percent_Identity=30.3724928366762, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583986, Length=349, Percent_Identity=30.3724928366762, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583984, Length=349, Percent_Identity=30.3724928366762, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24583992, Length=329, Percent_Identity=31.306990881459, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI281361666, Length=345, Percent_Identity=27.536231884058, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646341, Length=345, Percent_Identity=27.536231884058, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136796, Length=345, Percent_Identity=27.536231884058, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20129479, Length=275, Percent_Identity=31.2727272727273, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLII_TREPA (O83417)

Other databases:

- EMBL:   AE000520
- PIR:   A71329
- RefSeq:   NP_218842.1
- ProteinModelPortal:   O83417
- SMR:   O83417
- IntAct:   O83417
- MINT:   MINT-6479524
- GeneID:   2610816
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0402
- NMPDR:   fig|243276.1.peg.401
- TIGR:   TP_0402
- HOGENOM:   HBG565875
- OMA:   LMERSGM
- ProtClustDB:   CLSK218610
- BioCyc:   TPAL243276:TP_0402-MONOMER
- BRENDA:   3.6.3.14
- GO:   GO:0005737
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR022426
- SMART:   SM00382
- TIGRFAMs:   TIGR03498
- TIGRFAMs:   TIGR01026

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N

EC number: =3.6.3.14

Molecular weight: Translated: 47853; Mature: 47853

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEADLLCKYEVALRESEPVKYVGHVTAVRGLLIESRGPHAVVGELCRIVLRRQGRPLIAE
CCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
VVGLAGSTVKLMSYTDTHGVEVGCAVVAEGAALSVPVGDALLGRVLNAFGKAIDGKGEIY
HHHCCCCCEEEEEECCCCCCEEHHHEEECCCEEECCCCHHHHHHHHHHHHHCCCCCCCEE
APLRSEVLRASSNPMERLPITRQMVTGVRVLDSLLAVGCGQRLGIFSGSGVGKSTLMGMI
HHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ARNTDADVSVIALIGERGREVMDFVAHDLGPEGLKRSVIVSATSDESPLARVRGAYTATA
HCCCCCCEEEEEHHHHCCHHHHHHHHHCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
IAEYFRDQGKQVLLLFDSLTRFAKAQREIGLASGELPATRGYTPGVFETLPKLLERAGSF
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SMGSVTAFYTVLVDGDDLDEPISDAVRGIVDGHIVLSRALAQRNHYPAIDVLQSVSRLAH
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RVLGADMKEAVRIVRRALAVYAEVEDLVRVGAYQQGSDAELDRAIAMRAELERFLTQGAQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHH
ERVRFQDTVTSLSMLTGLSIAQPPSGV
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEADLLCKYEVALRESEPVKYVGHVTAVRGLLIESRGPHAVVGELCRIVLRRQGRPLIAE
CCCCCEEEEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHH
VVGLAGSTVKLMSYTDTHGVEVGCAVVAEGAALSVPVGDALLGRVLNAFGKAIDGKGEIY
HHHCCCCCEEEEEECCCCCCEEHHHEEECCCEEECCCCHHHHHHHHHHHHHCCCCCCCEE
APLRSEVLRASSNPMERLPITRQMVTGVRVLDSLLAVGCGQRLGIFSGSGVGKSTLMGMI
HHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ARNTDADVSVIALIGERGREVMDFVAHDLGPEGLKRSVIVSATSDESPLARVRGAYTATA
HCCCCCCEEEEEHHHHCCHHHHHHHHHCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHH
IAEYFRDQGKQVLLLFDSLTRFAKAQREIGLASGELPATRGYTPGVFETLPKLLERAGSF
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SMGSVTAFYTVLVDGDDLDEPISDAVRGIVDGHIVLSRALAQRNHYPAIDVLQSVSRLAH
CCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RVLGADMKEAVRIVRRALAVYAEVEDLVRVGAYQQGSDAELDRAIAMRAELERFLTQGAQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCHH
ERVRFQDTVTSLSMLTGLSIAQPPSGV
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876