Click here to switch to the map view.

The map label for this gene is cheA

Identifier: 189025596

GI number: 189025596

Start: 385758

End: 388196

Strand: Direct

Name: cheA

Synonym: TPASS_0363

Alternate gene names: 189025596

Gene position: 385758-388196 (Clockwise)

Preceding gene: 189025595

Following gene: 189025597

Centisome position: 33.85

GC content: 54.24

Gene sequence:

>2439_bases
GTGCCCATGAGCGATTACCTCGACGCGGGCAACGAAGAGTTGCTGAAGGATTTTTTCAGCGAGGCGGAGCAACAGGTTGA
GCAGCTCGAAAGCAATATACTCGTCATTGAGCAGGATCCCACCAATCGGGACGCTGTAGACGAGATTTTCCGTGCGGCGC
ACACCCTTAAGGGGGGTGCTGCGACTGTTGAGATGCACGAGTTGTCCGGCTTCACGCATGCGGTGGAGGATCTGCTGGAT
GGGATTCGCTCAGAGAAGGTAACTGTTGACGGGGCGGTTGTGGACTTGCTCCTGACGTCGTTGGATGTAATTAAGGCGAT
GCTCGAGTCCCGTGCGGGCGGTGGTCCCTACGCGGAGGATGTCTCGGATCTCGTTGCGCGTCTGCGCTCGTATCTGCCTG
CGTCTGGGACTGTGCCGGGGGCGGCGCGTGGATTGTCGGTGTCTTCGCCAAATGCAGCCGAAGCTGCAAAGGGGACCGCG
GTAGGTGAAGATGGGACGGAAGCCCCTCAGGTAGGGCGAGTGCCGCCGCTGTCTCTTCTTTCTGAATACGATCGGTTGGA
ATTGCGCGAGATCGTTCCGCCTGAGCACTCTGTCTACGCGCTTACGGTGCGTTTTGATGAGAGTAATCTGATGAACACGG
TCGGCGGTATCCAGGTGTTTACAGCGTTGAAGTCCTGCGCAAGCGTGCTCAAGACGGTTCCTGATTTCGACGCACTGTAT
CAGGACATGTTCCATGAGTATGTTGTGTACTTCGTTTCCACTGTGCAGGATTCAGTATGTGTGTCGCAGGTTGCTTCGAT
TCCGGACGTTACGCTTTCGGTGAGTGTAGCGGAAGTTGCGCTTGCAGATCTGTGTACTCCCCTCTCTGAACATGGGGAGC
TGGGTGTTTGCGCAGACGCGGGGACAGGTGGTGTGTCCGAAGGGAGCGGCGCTGCCGTGCGCAGCGGAGGGGAACGCGTT
CCTAACTCCCTGCCGAAACAGGTTGCCGGGTGCGCGGTGCCTTCTGCAAAGGACTCATCAAAGGCTACCTCAAGCGGCTA
CGGCTCGGGGTCCGTGTTGCGCGTAGATGCGAAACGCATCGATTATCTTCTGAATTTGGTAAGTGAGACGGTGATTATCA
AGGCCTCGCTCAATCAGAGTGCGCTTGAATTTGGGGAGGTGTACACCCTATTCCAAAACGCTAATGGCGCGTACAAGGAG
CGTTTGCGTAAGTTTTTTGATAGGGTTCCCGCTTACTTAGAAAAGGTAAAGAACGGTCAGGACGCAGATGCGGTGCGCAA
GGGGATGATAGCAGAGGCTGTCGGTGTCTTTGACATTTTTTCTTCGTTTGAGAATGGACTGAAACAGTCCGTCACTAAGT
TTCGGTCTTCTGCTCAGAATTTGGGGCGTATTTCTGGTGAGCTTCAAGAAGGTGTGATGAAAATCCGCATGGTGCCTATT
AGCCAGATTTTCAGTCGTTATCCGCGTGTGGTGCGCGATCTCTCGCGGGACTTGCGTAAAGAGGTGCGGTTGGTCATTGA
AGGAGAGGAGACGGAGCTTGATAAGTCTGTGGTTGAAGATTTGCTCGATCCCATTATGCACTGCGTGCGTAATTCTCTCG
ACCACGGCATAGAAGCGCCTGAAGTTCGCGCGCGCTCTGGAAAACCGGCGCAAGGTACGCTTCTCCTGCGCGCAAGCAAC
GAAGGAAATATGATCGTTATTGAGGTTGCCGATGACGGGCGTGGCATCGACGTGGAGGCAGTGAAGACGAAAGCAGTTGA
GCGAGGTGTGTTGCACCCAGGCAAGAACCTCACTGAGGTTGAGGCGTTCCAACTTATTTTTGCTCCCGGTTTTTCAACCT
CTCGGTCGGTTTCTAATGTTTCTGGTCGGGGTGTGGGGCTTGATGTGGTGAAGACTCACATTGAGAGGCTCAATGGCACT
GTCTCCGTCTTTTCGGAAGTGCAGAAGGGAACGCGCTTTGTCATAAAGCTGCCGCTTACACTGGCAATTATTCAGGGGCT
CTTGATACGGGTGGGGCAGGAGGTGTACTCGATACCGATAGCTTCGGTCATCGAAAGCCATCGTATCAAGAGTGAAGAGA
TTAACCGGATTGATAACTACGAGGTGTTCAATGTGCGGAACGAGGTCATTAGCTTGCTGCGTCTCGATAGGCTGTTCGGT
ATCAGCTGCGATGATGAGGTGACCGGTCAGTATCACTATGTGGTTATAGTTGGTGCGGCAGAGAAAAAGGTGGGGCTCAT
GGTGGATGCGCTGATTGGTGAGGAGGACGTAGTCATCAAGCCACTGCGGGATCAATTCACTAGTTCCCCTGGTATTGCAG
GGGCATCTATCCTGGGTGACGGTTCGGTGTCGTTGATTATCGATGTGGGGCAGCTGCTTGAGCTTGGGTTGAAGCGGGAA
ATATTGGCGCGTGAGCGTCGAGAAGCCACGGTGTGGTAG

Upstream 100 bases:

>100_bases
GCGGAGTCTATTCTCGGCTGATGGAAGTGTCAAGGGATGCAGCGGGTGGCGGGGTCTTTTGGACGTTGCCTTGACCAAAG
GCTGAGAATGCGGGAAGATT

Downstream 100 bases:

>100_bases
GCGATCTGGGGCACGGATTGGGGACTATGATAGAGCATATGGAAGCAGAGATCGGCATTCGGGAAAGTTTCGACGGGGGC
GTACGTGAGCCGCTTGCGGT

Product: chemotaxis histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 812; Mature: 811

Protein sequence:

>812_residues
MPMSDYLDAGNEELLKDFFSEAEQQVEQLESNILVIEQDPTNRDAVDEIFRAAHTLKGGAATVEMHELSGFTHAVEDLLD
GIRSEKVTVDGAVVDLLLTSLDVIKAMLESRAGGGPYAEDVSDLVARLRSYLPASGTVPGAARGLSVSSPNAAEAAKGTA
VGEDGTEAPQVGRVPPLSLLSEYDRLELREIVPPEHSVYALTVRFDESNLMNTVGGIQVFTALKSCASVLKTVPDFDALY
QDMFHEYVVYFVSTVQDSVCVSQVASIPDVTLSVSVAEVALADLCTPLSEHGELGVCADAGTGGVSEGSGAAVRSGGERV
PNSLPKQVAGCAVPSAKDSSKATSSGYGSGSVLRVDAKRIDYLLNLVSETVIIKASLNQSALEFGEVYTLFQNANGAYKE
RLRKFFDRVPAYLEKVKNGQDADAVRKGMIAEAVGVFDIFSSFENGLKQSVTKFRSSAQNLGRISGELQEGVMKIRMVPI
SQIFSRYPRVVRDLSRDLRKEVRLVIEGEETELDKSVVEDLLDPIMHCVRNSLDHGIEAPEVRARSGKPAQGTLLLRASN
EGNMIVIEVADDGRGIDVEAVKTKAVERGVLHPGKNLTEVEAFQLIFAPGFSTSRSVSNVSGRGVGLDVVKTHIERLNGT
VSVFSEVQKGTRFVIKLPLTLAIIQGLLIRVGQEVYSIPIASVIESHRIKSEEINRIDNYEVFNVRNEVISLLRLDRLFG
ISCDDEVTGQYHYVVIVGAAEKKVGLMVDALIGEEDVVIKPLRDQFTSSPGIAGASILGDGSVSLIIDVGQLLELGLKRE
ILARERREATVW

Sequences:

>Translated_812_residues
MPMSDYLDAGNEELLKDFFSEAEQQVEQLESNILVIEQDPTNRDAVDEIFRAAHTLKGGAATVEMHELSGFTHAVEDLLD
GIRSEKVTVDGAVVDLLLTSLDVIKAMLESRAGGGPYAEDVSDLVARLRSYLPASGTVPGAARGLSVSSPNAAEAAKGTA
VGEDGTEAPQVGRVPPLSLLSEYDRLELREIVPPEHSVYALTVRFDESNLMNTVGGIQVFTALKSCASVLKTVPDFDALY
QDMFHEYVVYFVSTVQDSVCVSQVASIPDVTLSVSVAEVALADLCTPLSEHGELGVCADAGTGGVSEGSGAAVRSGGERV
PNSLPKQVAGCAVPSAKDSSKATSSGYGSGSVLRVDAKRIDYLLNLVSETVIIKASLNQSALEFGEVYTLFQNANGAYKE
RLRKFFDRVPAYLEKVKNGQDADAVRKGMIAEAVGVFDIFSSFENGLKQSVTKFRSSAQNLGRISGELQEGVMKIRMVPI
SQIFSRYPRVVRDLSRDLRKEVRLVIEGEETELDKSVVEDLLDPIMHCVRNSLDHGIEAPEVRARSGKPAQGTLLLRASN
EGNMIVIEVADDGRGIDVEAVKTKAVERGVLHPGKNLTEVEAFQLIFAPGFSTSRSVSNVSGRGVGLDVVKTHIERLNGT
VSVFSEVQKGTRFVIKLPLTLAIIQGLLIRVGQEVYSIPIASVIESHRIKSEEINRIDNYEVFNVRNEVISLLRLDRLFG
ISCDDEVTGQYHYVVIVGAAEKKVGLMVDALIGEEDVVIKPLRDQFTSSPGIAGASILGDGSVSLIIDVGQLLELGLKRE
ILARERREATVW
>Mature_811_residues
PMSDYLDAGNEELLKDFFSEAEQQVEQLESNILVIEQDPTNRDAVDEIFRAAHTLKGGAATVEMHELSGFTHAVEDLLDG
IRSEKVTVDGAVVDLLLTSLDVIKAMLESRAGGGPYAEDVSDLVARLRSYLPASGTVPGAARGLSVSSPNAAEAAKGTAV
GEDGTEAPQVGRVPPLSLLSEYDRLELREIVPPEHSVYALTVRFDESNLMNTVGGIQVFTALKSCASVLKTVPDFDALYQ
DMFHEYVVYFVSTVQDSVCVSQVASIPDVTLSVSVAEVALADLCTPLSEHGELGVCADAGTGGVSEGSGAAVRSGGERVP
NSLPKQVAGCAVPSAKDSSKATSSGYGSGSVLRVDAKRIDYLLNLVSETVIIKASLNQSALEFGEVYTLFQNANGAYKER
LRKFFDRVPAYLEKVKNGQDADAVRKGMIAEAVGVFDIFSSFENGLKQSVTKFRSSAQNLGRISGELQEGVMKIRMVPIS
QIFSRYPRVVRDLSRDLRKEVRLVIEGEETELDKSVVEDLLDPIMHCVRNSLDHGIEAPEVRARSGKPAQGTLLLRASNE
GNMIVIEVADDGRGIDVEAVKTKAVERGVLHPGKNLTEVEAFQLIFAPGFSTSRSVSNVSGRGVGLDVVKTHIERLNGTV
SVFSEVQKGTRFVIKLPLTLAIIQGLLIRVGQEVYSIPIASVIESHRIKSEEINRIDNYEVFNVRNEVISLLRLDRLFGI
SCDDEVTGQYHYVVIVGAAEKKVGLMVDALIGEEDVVIKPLRDQFTSSPGIAGASILGDGSVSLIIDVGQLLELGLKREI
LARERREATVW

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain

Homologues:

Organism=Escherichia coli, GI1788197, Length=356, Percent_Identity=44.1011235955056, Blast_Score=281, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEA_TREPA (P96123)

Other databases:

- EMBL:   U61851
- EMBL:   AE000520
- PIR:   A71335
- RefSeq:   NP_218803.1
- ProteinModelPortal:   P96123
- GeneID:   2611783
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0363
- NMPDR:   fig|243276.1.peg.362
- TIGR:   TP_0363
- HOGENOM:   HBG705053
- OMA:   VYMVFEQ
- ProtClustDB:   CLSK375147
- BioCyc:   TPAL243276:TP_0363-MONOMER
- BRENDA:   2.7.13.3
- GO:   GO:0005737
- GO:   GO:0006935
- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808
- Gene3D:   G3DSA:3.30.565.10
- Gene3D:   G3DSA:1.20.120.160
- Gene3D:   G3DSA:1.10.287.560
- PRINTS:   PR00344
- SMART:   SM00260
- SMART:   SM00387
- SMART:   SM00073

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2; SSF55874 ATP_bd_ATPase; SSF50341 CheW; SSF47384 His_kin_homodim; SSF47226 Hpt

EC number: =2.7.13.3

Molecular weight: Translated: 87694; Mature: 87562

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50851 CHEW; PS50109 HIS_KIN; PS50894 HPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSDYLDAGNEELLKDFFSEAEQQVEQLESNILVIEQDPTNRDAVDEIFRAAHTLKGGA
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
ATVEMHELSGFTHAVEDLLDGIRSEKVTVDGAVVDLLLTSLDVIKAMLESRAGGGPYAED
EEEEHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VSDLVARLRSYLPASGTVPGAARGLSVSSPNAAEAAKGTAVGEDGTEAPQVGRVPPLSLL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
SEYDRLELREIVPPEHSVYALTVRFDESNLMNTVGGIQVFTALKSCASVLKTVPDFDALY
HHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QDMFHEYVVYFVSTVQDSVCVSQVASIPDVTLSVSVAEVALADLCTPLSEHGELGVCADA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHCCCEEEEECC
GTGGVSEGSGAAVRSGGERVPNSLPKQVAGCAVPSAKDSSKATSSGYGSGSVLRVDAKRI
CCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHH
DYLLNLVSETVIIKASLNQSALEFGEVYTLFQNANGAYKERLRKFFDRVPAYLEKVKNGQ
HHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DADAVRKGMIAEAVGVFDIFSSFENGLKQSVTKFRSSAQNLGRISGELQEGVMKIRMVPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCH
SQIFSRYPRVVRDLSRDLRKEVRLVIEGEETELDKSVVEDLLDPIMHCVRNSLDHGIEAP
HHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVRARSGKPAQGTLLLRASNEGNMIVIEVADDGRGIDVEAVKTKAVERGVLHPGKNLTEV
CHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
EAFQLIFAPGFSTSRSVSNVSGRGVGLDVVKTHIERLNGTVSVFSEVQKGTRFVIKLPLT
HHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEHHHH
LAIIQGLLIRVGQEVYSIPIASVIESHRIKSEEINRIDNYEVFNVRNEVISLLRLDRLFG
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHC
ISCDDEVTGQYHYVVIVGAAEKKVGLMVDALIGEEDVVIKPLRDQFTSSPGIAGASILGD
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEEECHHHHCCCCCCCCCCEEECC
GSVSLIIDVGQLLELGLKREILARERREATVW
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PMSDYLDAGNEELLKDFFSEAEQQVEQLESNILVIEQDPTNRDAVDEIFRAAHTLKGGA
CCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
ATVEMHELSGFTHAVEDLLDGIRSEKVTVDGAVVDLLLTSLDVIKAMLESRAGGGPYAED
EEEEHHHHCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VSDLVARLRSYLPASGTVPGAARGLSVSSPNAAEAAKGTAVGEDGTEAPQVGRVPPLSLL
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
SEYDRLELREIVPPEHSVYALTVRFDESNLMNTVGGIQVFTALKSCASVLKTVPDFDALY
HHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
QDMFHEYVVYFVSTVQDSVCVSQVASIPDVTLSVSVAEVALADLCTPLSEHGELGVCADA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHCCCEEEEECC
GTGGVSEGSGAAVRSGGERVPNSLPKQVAGCAVPSAKDSSKATSSGYGSGSVLRVDAKRI
CCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECHHHH
DYLLNLVSETVIIKASLNQSALEFGEVYTLFQNANGAYKERLRKFFDRVPAYLEKVKNGQ
HHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DADAVRKGMIAEAVGVFDIFSSFENGLKQSVTKFRSSAQNLGRISGELQEGVMKIRMVPI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCH
SQIFSRYPRVVRDLSRDLRKEVRLVIEGEETELDKSVVEDLLDPIMHCVRNSLDHGIEAP
HHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EVRARSGKPAQGTLLLRASNEGNMIVIEVADDGRGIDVEAVKTKAVERGVLHPGKNLTEV
CHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
EAFQLIFAPGFSTSRSVSNVSGRGVGLDVVKTHIERLNGTVSVFSEVQKGTRFVIKLPLT
HHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEHHHH
LAIIQGLLIRVGQEVYSIPIASVIESHRIKSEEINRIDNYEVFNVRNEVISLLRLDRLFG
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHC
ISCDDEVTGQYHYVVIVGAAEKKVGLMVDALIGEEDVVIKPLRDQFTSSPGIAGASILGD
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCEEEECHHHHCCCCCCCCCCEEECC
GSVSLIIDVGQLLELGLKREILARERREATVW
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9255518; 9665876