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The map label for this gene is rsbU [H]

Identifier: 189025451

GI number: 189025451

Start: 223384

End: 224853

Strand: Direct

Name: rsbU [H]

Synonym: TPASS_0218

Alternate gene names: 189025451

Gene position: 223384-224853 (Clockwise)

Preceding gene: 189025450

Following gene: 189025452

Centisome position: 19.6

GC content: 46.39

Gene sequence:

>1470_bases
GTGATTCGCAGAAGGCTCGCAATTGTAAAGGCAGGTTCATTCGCACTCCTGGCGCTTTTTTTTTCAATATTTTTGCGCTT
TCTCAGTCCGCGGTATTCGTTTCTCGGTCGTTTCGTTTCTGCGCGCGATATGGCGCTGTTGATTTCTCGGTATGAGCATT
TGCCTGAGCTTTCTTCGCGTGATCGAGCCTTGCTGGTAGGTTTCGTTTTCATGATTTTTGCGCTTGCGCTTACAGAAATC
CAACGCTATGCGCACGGGCGCATCCGTCTTGTTGTCTATCGACAAACTGAAACGCGTCTTTTTGAACATTTTATTACACT
GCTGCGCTTTTGCTACCGTAATGAACAACTTGTTGCTGCCTTCCAGGAGGTGCTTGAATATCGCGCCGATTGCGCAGTGC
TCTTAATGGATACGATAAGTAATCGTGTTATTTACAACAGTGCTGCACGATTTGTTTCAGACACACGCACGTATGATCTT
GTGCTTCATAAGTTTTCTATGGACTACACGTGGCACTGGTCAGACGGTATATATTTTTTTGATGATGATCTGTGTCTTAT
GTCTGACCGACGTCGGGCTCGTGGGGTATGTCTTTCCAGTGGAGAGCTGCGTCTTTTTATAGTATGTCGTTTTATCCGTG
CTGTTGAGCGCGAAGTTATATCGCTCTTGTTCAAAGAGTTTGAAGAGTATTTAAATCGAAAGAGGAACATGAGCACTTTG
TTGTTGTACTCCCATGTATCCCAGGAATGGGCAATGATGGCGCGTGTACAGCGCGCACTTTTGCCTAAGGCGCTCCCACA
TACCAAGGAAATATGCGTCGGGGCATTCTATCAGCCACTGGTTAATGTATCTGGGGATTATTACGACGTTATTTCAATTG
ATGAACACCTGTTTTTATTTGTAATTGGAGATGTTTCTGGCAAAGGTTTGGCCGCGTCGTTAGTTATGGGTGTTGTGCTC
AGTACGATTCGCATCGTGGAAGACAAAAAGAATCTTCCTGAGATTTTGTATGCGGTGGACCGGGCAGTAAAGCGTATGCA
TCTCCACGATAAGTACACGACCTTATTCTTGGGATTAATTGACACAGCGGGTATGAATATTCGCTACATTAACGCATCGA
TGGAAAGTCCCCTTGTCTTTACCCAGGCGGGAGAGGCGCACGAAGTGTATCATCTTCATTCGAATTGTCCAGTTATTGGC
ATTGTGGATCTGCCCCCTATACAGATTCATGAGCGTACGTTGTGTCCTGGGGATGTAATGGTCATGGTATCAGACGGGGT
AGTTGAAGTAGTCAATGCCCAAGGAGTAGAGCTGCGCGACGCCGATGAGTATCTTCACATATTAGAGCGCCATGTGGGTG
AACACCCTGCGCAGATGGCTCAAAGTATTGCAGCTCTAGCATTGAATTTCAGTGCGGATCGCACTACCCATGACGACATG
ACCATTGTGACTGTGCAGGTGAAGAGGTAG

Upstream 100 bases:

>100_bases
AGTTGGCTTCATCGTGATGGGTGCGTGTGCTATCTGAGTTTTCTTCCCACAGTTTAAAAGACAACGTGTTTTTGAAGCAG
CCATACAAAGGGAACGGTAG

Downstream 100 bases:

>100_bases
GTAATGGGGTTGCTATTTTTTTCTTACCTCTTTGTCGCGGTTTTTGTTTTCGACGTATTCTGTTTAAAGTTTTACACAAG
GCGCGCGTATGCACTGCTGG

Product: sigma factor SigB regulation protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MIRRRLAIVKAGSFALLALFFSIFLRFLSPRYSFLGRFVSARDMALLISRYEHLPELSSRDRALLVGFVFMIFALALTEI
QRYAHGRIRLVVYRQTETRLFEHFITLLRFCYRNEQLVAAFQEVLEYRADCAVLLMDTISNRVIYNSAARFVSDTRTYDL
VLHKFSMDYTWHWSDGIYFFDDDLCLMSDRRRARGVCLSSGELRLFIVCRFIRAVEREVISLLFKEFEEYLNRKRNMSTL
LLYSHVSQEWAMMARVQRALLPKALPHTKEICVGAFYQPLVNVSGDYYDVISIDEHLFLFVIGDVSGKGLAASLVMGVVL
STIRIVEDKKNLPEILYAVDRAVKRMHLHDKYTTLFLGLIDTAGMNIRYINASMESPLVFTQAGEAHEVYHLHSNCPVIG
IVDLPPIQIHERTLCPGDVMVMVSDGVVEVVNAQGVELRDADEYLHILERHVGEHPAQMAQSIAALALNFSADRTTHDDM
TIVTVQVKR

Sequences:

>Translated_489_residues
MIRRRLAIVKAGSFALLALFFSIFLRFLSPRYSFLGRFVSARDMALLISRYEHLPELSSRDRALLVGFVFMIFALALTEI
QRYAHGRIRLVVYRQTETRLFEHFITLLRFCYRNEQLVAAFQEVLEYRADCAVLLMDTISNRVIYNSAARFVSDTRTYDL
VLHKFSMDYTWHWSDGIYFFDDDLCLMSDRRRARGVCLSSGELRLFIVCRFIRAVEREVISLLFKEFEEYLNRKRNMSTL
LLYSHVSQEWAMMARVQRALLPKALPHTKEICVGAFYQPLVNVSGDYYDVISIDEHLFLFVIGDVSGKGLAASLVMGVVL
STIRIVEDKKNLPEILYAVDRAVKRMHLHDKYTTLFLGLIDTAGMNIRYINASMESPLVFTQAGEAHEVYHLHSNCPVIG
IVDLPPIQIHERTLCPGDVMVMVSDGVVEVVNAQGVELRDADEYLHILERHVGEHPAQMAQSIAALALNFSADRTTHDDM
TIVTVQVKR
>Mature_489_residues
MIRRRLAIVKAGSFALLALFFSIFLRFLSPRYSFLGRFVSARDMALLISRYEHLPELSSRDRALLVGFVFMIFALALTEI
QRYAHGRIRLVVYRQTETRLFEHFITLLRFCYRNEQLVAAFQEVLEYRADCAVLLMDTISNRVIYNSAARFVSDTRTYDL
VLHKFSMDYTWHWSDGIYFFDDDLCLMSDRRRARGVCLSSGELRLFIVCRFIRAVEREVISLLFKEFEEYLNRKRNMSTL
LLYSHVSQEWAMMARVQRALLPKALPHTKEICVGAFYQPLVNVSGDYYDVISIDEHLFLFVIGDVSGKGLAASLVMGVVL
STIRIVEDKKNLPEILYAVDRAVKRMHLHDKYTTLFLGLIDTAGMNIRYINASMESPLVFTQAGEAHEVYHLHSNCPVIG
IVDLPPIQIHERTLCPGDVMVMVSDGVVEVVNAQGVELRDADEYLHILERHVGEHPAQMAQSIAALALNFSADRTTHDDM
TIVTVQVKR

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 56171; Mature: 56171

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRRLAIVKAGSFALLALFFSIFLRFLSPRYSFLGRFVSARDMALLISRYEHLPELSSR
CCCHHEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DRALLVGFVFMIFALALTEIQRYAHGRIRLVVYRQTETRLFEHFITLLRFCYRNEQLVAA
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHH
FQEVLEYRADCAVLLMDTISNRVIYNSAARFVSDTRTYDLVLHKFSMDYTWHWSDGIYFF
HHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHCCCHHHHEEEEECCCEEEEECCCEEEE
DDDLCLMSDRRRARGVCLSSGELRLFIVCRFIRAVEREVISLLFKEFEEYLNRKRNMSTL
ECCEEECCCCHHHCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
LLYSHVSQEWAMMARVQRALLPKALPHTKEICVGAFYQPLVNVSGDYYDVISIDEHLFLF
EHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEE
VIGDVSGKGLAASLVMGVVLSTIRIVEDKKNLPEILYAVDRAVKRMHLHDKYTTLFLGLI
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTAGMNIRYINASMESPLVFTQAGEAHEVYHLHSNCPVIGIVDLPPIQIHERTLCPGDVM
HCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEE
VMVSDGVVEVVNAQGVELRDADEYLHILERHVGEHPAQMAQSIAALALNFSADRTTHDDM
EEEECCEEEEECCCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCE
TIVTVQVKR
EEEEEEECC
>Mature Secondary Structure
MIRRRLAIVKAGSFALLALFFSIFLRFLSPRYSFLGRFVSARDMALLISRYEHLPELSSR
CCCHHEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DRALLVGFVFMIFALALTEIQRYAHGRIRLVVYRQTETRLFEHFITLLRFCYRNEQLVAA
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHH
FQEVLEYRADCAVLLMDTISNRVIYNSAARFVSDTRTYDLVLHKFSMDYTWHWSDGIYFF
HHHHHHHHCCHHHHHHHHHCCCEEEHHHHHHHHCCCHHHHEEEEECCCEEEEECCCEEEE
DDDLCLMSDRRRARGVCLSSGELRLFIVCRFIRAVEREVISLLFKEFEEYLNRKRNMSTL
ECCEEECCCCHHHCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHE
LLYSHVSQEWAMMARVQRALLPKALPHTKEICVGAFYQPLVNVSGDYYDVISIDEHLFLF
EHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEE
VIGDVSGKGLAASLVMGVVLSTIRIVEDKKNLPEILYAVDRAVKRMHLHDKYTTLFLGLI
EEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTAGMNIRYINASMESPLVFTQAGEAHEVYHLHSNCPVIGIVDLPPIQIHERTLCPGDVM
HCCCCEEEEEECCCCCCEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCEE
VMVSDGVVEVVNAQGVELRDADEYLHILERHVGEHPAQMAQSIAALALNFSADRTTHDDM
EEEECCEEEEECCCCCEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCE
TIVTVQVKR
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]