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The map label for this gene is rsbU [H]

Identifier: 189025452

GI number: 189025452

Start: 224857

End: 227004

Strand: Direct

Name: rsbU [H]

Synonym: TPASS_0219

Alternate gene names: 189025452

Gene position: 224857-227004 (Clockwise)

Preceding gene: 189025451

Following gene: 189025453

Centisome position: 19.73

GC content: 41.67

Gene sequence:

>2148_bases
ATGGGGTTGCTATTTTTTTCTTACCTCTTTGTCGCGGTTTTTGTTTTCGACGTATTCTGTTTAAAGTTTTACACAAGGCG
CGCGTATGCACTGCTGGCAAATATAGCCTTGGTATCAGGTGTAGCCTCTTTTTTCTTGTCTTTGTCGCTCACCGCTGTCC
TGTACGGTAAAATGAATATCCAGGCATTTTTATTTAAAATTGCACTGATATTTTTTACCCACGCTTCATATCTGTTTTCT
GACATGGCGTATCAACTACCCTATTTTAAAAAAAATAAGAGATTTTTCTTATGTAATACGACGATTCATTTGTTTGGAAT
TCTCATAATCATATTTGGCATGGGTCCGTTTAAATGGAACGTTCTGGTGAGTTTTAAATTTTACCAAAATTATTTGTTTT
CTTCTGTTTCGGGTATTGTGTTATACGCGGCGCTTTTTTTTCTAATCATTCCCTGTGTTACGTTCGCAACTTTGGTGAAA
AAAGCATTCATGATGAAAAGTATTGCATATCGGCAACAACTCCTGTTTCTCGCGGGGGCAGTGGCTTTGGGTTTTATCAC
GTGGGTTATTATCTTGTTCTTGTTTGCGGTTTTTCCCTGGGTGTTTGTGTTTTTTCCCTTAGGAGGTGTATTTATAGTTT
TATTTTCTCAGTGGGCATTTGCGTCTACTGGAATTGTTTCCTTTAAAGAAGTGGTGTTTGCGCTATCGCGTTTTGTGTTA
TGCACGGTGGGGTTTTCATGTACAGCAGGTTACATATCGGTATTTTGGGTGCACCGTTTTTCTACGCTTGATATGCAGTT
TGTATTTGGTTTTTTTATCGTATATGCGCTGTTTGCTCTACGTGATTATGCCTTTGATGCATGTAGCGTGTTTTTTGGGG
AAATTGCTGATTCTGGACAGAAGTTAGCCGCAGAGCTTCAAGCATTAGATTACACGGCAAAACCTGCGCAGGTACTCCGT
ACGTTTATGGACACATTGCGTATGCGCATCGCGTGTAGAGGATTGACATTTTTACTTGCTGACGAGGCAGGCGTATTCAA
GACGGTGTATTCTGATTTTGAAGAGATGGCAACGCATGAGATGGAACATCAGTCGTTACAGTATTTTTTCAATCAAGATG
TTCTTATGATCAGAAAATCGGATCCAGTTATTGACCATGCACGTCAGGCAATTCGGACAGATATCCTGCATTTTTTTGAT
ATAACGCACGCCCAGATGATTGTCTTGATTCGGGAAGCTCAAAAACTTATTGGATGTCTATGTTTTGGTATGAAAAACAA
CGGCGTAGAATATAGCAATCATGATCAGCATGTTTTAGAAAAGTTGTATTCACACTTTGTATTGGTTTCCTATTACTTAC
AGAATATTGCAAAGCAAGACGTGGTTATCACGGTGGACAAAGAACTTAAAATGTCCCATCAGATTATTGAGTCAATACAA
CGGAAAAGGGATTTTATTCAGGATGCCTCCGTTGAGGTGGATTCAATTGCGTATTCTGCGCACCAACTTGGGGGCGATTT
TGTTGATTTCATTAAACTGTCCGAGAAAAGATACCTGCTAGTTATCGGGGATGTATCGGGGAAAGGTCTGGCAGCGAGTA
TGTCAATGGTGATTTTGAAGTCTGTACTGAGTACCTTTCTGCGGGGACTGTGCCTGGAAGAAACGGCAGTATTTACAACC
TTTATTGAGAAGATAAACCGGTTTATCAAAGACAATTTGCCGTGTGGGACTTTTTTTGCGGGTGTATTCTGTATTCTTGA
CCTGGCAACCCATACGCTCTACTATGCGAACTGTGGCATACCGCTCATGTCGATGTACGTCGCTTCATACAAGAACGTGG
TGGAGATACAAGGCGAGGGGCGCGTGCTGGGTTTTGTTAAAGATGTTATGCCCTTTTTGCGGGTGAGGAAAGTTCAACTC
GGTCAGGGGGACGTGGTGGTATTTTCCACTGATGGAATGGTAGAAGTACAAAATTTGCAGCGGGAGCGCTTTGGTAACGA
GCGTGTGGATAGGATTCTACAGGAAAGTCATGGTCTTCCGGTTTCTCAAATTACCCGTACTATTTATGCTCGGCTGTGTG
AGTTTATGGCGCGAGATATGCAGGATGATGTAACTGTTCTGGCAATAAAGTGCCTTGGGCCTCGGTAG

Upstream 100 bases:

>100_bases
GATGGCTCAAAGTATTGCAGCTCTAGCATTGAATTTCAGTGCGGATCGCACTACCCATGACGACATGACCATTGTGACTG
TGCAGGTGAAGAGGTAGGTA

Downstream 100 bases:

>100_bases
GAAATGAGGAAAAGTTCGGGAGCGCCGTATGGATAATATAAATATCGCCAAAGACGTTCGGCCTGGGTGCGTTTTATTAA
CGGTGACTGGAGCGGTCAGC

Product: sigma factor SigB regulation protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MGLLFFSYLFVAVFVFDVFCLKFYTRRAYALLANIALVSGVASFFLSLSLTAVLYGKMNIQAFLFKIALIFFTHASYLFS
DMAYQLPYFKKNKRFFLCNTTIHLFGILIIIFGMGPFKWNVLVSFKFYQNYLFSSVSGIVLYAALFFLIIPCVTFATLVK
KAFMMKSIAYRQQLLFLAGAVALGFITWVIILFLFAVFPWVFVFFPLGGVFIVLFSQWAFASTGIVSFKEVVFALSRFVL
CTVGFSCTAGYISVFWVHRFSTLDMQFVFGFFIVYALFALRDYAFDACSVFFGEIADSGQKLAAELQALDYTAKPAQVLR
TFMDTLRMRIACRGLTFLLADEAGVFKTVYSDFEEMATHEMEHQSLQYFFNQDVLMIRKSDPVIDHARQAIRTDILHFFD
ITHAQMIVLIREAQKLIGCLCFGMKNNGVEYSNHDQHVLEKLYSHFVLVSYYLQNIAKQDVVITVDKELKMSHQIIESIQ
RKRDFIQDASVEVDSIAYSAHQLGGDFVDFIKLSEKRYLLVIGDVSGKGLAASMSMVILKSVLSTFLRGLCLEETAVFTT
FIEKINRFIKDNLPCGTFFAGVFCILDLATHTLYYANCGIPLMSMYVASYKNVVEIQGEGRVLGFVKDVMPFLRVRKVQL
GQGDVVVFSTDGMVEVQNLQRERFGNERVDRILQESHGLPVSQITRTIYARLCEFMARDMQDDVTVLAIKCLGPR

Sequences:

>Translated_715_residues
MGLLFFSYLFVAVFVFDVFCLKFYTRRAYALLANIALVSGVASFFLSLSLTAVLYGKMNIQAFLFKIALIFFTHASYLFS
DMAYQLPYFKKNKRFFLCNTTIHLFGILIIIFGMGPFKWNVLVSFKFYQNYLFSSVSGIVLYAALFFLIIPCVTFATLVK
KAFMMKSIAYRQQLLFLAGAVALGFITWVIILFLFAVFPWVFVFFPLGGVFIVLFSQWAFASTGIVSFKEVVFALSRFVL
CTVGFSCTAGYISVFWVHRFSTLDMQFVFGFFIVYALFALRDYAFDACSVFFGEIADSGQKLAAELQALDYTAKPAQVLR
TFMDTLRMRIACRGLTFLLADEAGVFKTVYSDFEEMATHEMEHQSLQYFFNQDVLMIRKSDPVIDHARQAIRTDILHFFD
ITHAQMIVLIREAQKLIGCLCFGMKNNGVEYSNHDQHVLEKLYSHFVLVSYYLQNIAKQDVVITVDKELKMSHQIIESIQ
RKRDFIQDASVEVDSIAYSAHQLGGDFVDFIKLSEKRYLLVIGDVSGKGLAASMSMVILKSVLSTFLRGLCLEETAVFTT
FIEKINRFIKDNLPCGTFFAGVFCILDLATHTLYYANCGIPLMSMYVASYKNVVEIQGEGRVLGFVKDVMPFLRVRKVQL
GQGDVVVFSTDGMVEVQNLQRERFGNERVDRILQESHGLPVSQITRTIYARLCEFMARDMQDDVTVLAIKCLGPR
>Mature_714_residues
GLLFFSYLFVAVFVFDVFCLKFYTRRAYALLANIALVSGVASFFLSLSLTAVLYGKMNIQAFLFKIALIFFTHASYLFSD
MAYQLPYFKKNKRFFLCNTTIHLFGILIIIFGMGPFKWNVLVSFKFYQNYLFSSVSGIVLYAALFFLIIPCVTFATLVKK
AFMMKSIAYRQQLLFLAGAVALGFITWVIILFLFAVFPWVFVFFPLGGVFIVLFSQWAFASTGIVSFKEVVFALSRFVLC
TVGFSCTAGYISVFWVHRFSTLDMQFVFGFFIVYALFALRDYAFDACSVFFGEIADSGQKLAAELQALDYTAKPAQVLRT
FMDTLRMRIACRGLTFLLADEAGVFKTVYSDFEEMATHEMEHQSLQYFFNQDVLMIRKSDPVIDHARQAIRTDILHFFDI
THAQMIVLIREAQKLIGCLCFGMKNNGVEYSNHDQHVLEKLYSHFVLVSYYLQNIAKQDVVITVDKELKMSHQIIESIQR
KRDFIQDASVEVDSIAYSAHQLGGDFVDFIKLSEKRYLLVIGDVSGKGLAASMSMVILKSVLSTFLRGLCLEETAVFTTF
IEKINRFIKDNLPCGTFFAGVFCILDLATHTLYYANCGIPLMSMYVASYKNVVEIQGEGRVLGFVKDVMPFLRVRKVQLG
QGDVVVFSTDGMVEVQNLQRERFGNERVDRILQESHGLPVSQITRTIYARLCEFMARDMQDDVTVLAIKCLGPR

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 81441; Mature: 81310

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLFFSYLFVAVFVFDVFCLKFYTRRAYALLANIALVSGVASFFLSLSLTAVLYGKMNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAFLFKIALIFFTHASYLFSDMAYQLPYFKKNKRFFLCNTTIHLFGILIIIFGMGPFKWN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCHHHHHHHHHHHHCCCCEEEE
VLVSFKFYQNYLFSSVSGIVLYAALFFLIIPCVTFATLVKKAFMMKSIAYRQQLLFLAGA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALGFITWVIILFLFAVFPWVFVFFPLGGVFIVLFSQWAFASTGIVSFKEVVFALSRFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
CTVGFSCTAGYISVFWVHRFSTLDMQFVFGFFIVYALFALRDYAFDACSVFFGEIADSGQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KLAAELQALDYTAKPAQVLRTFMDTLRMRIACRGLTFLLADEAGVFKTVYSDFEEMATHE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHHHHHH
MEHQSLQYFFNQDVLMIRKSDPVIDHARQAIRTDILHFFDITHAQMIVLIREAQKLIGCL
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFGMKNNGVEYSNHDQHVLEKLYSHFVLVSYYLQNIAKQDVVITVDKELKMSHQIIESIQ
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
RKRDFIQDASVEVDSIAYSAHQLGGDFVDFIKLSEKRYLLVIGDVSGKGLAASMSMVILK
HHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
SVLSTFLRGLCLEETAVFTTFIEKINRFIKDNLPCGTFFAGVFCILDLATHTLYYANCGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCH
PLMSMYVASYKNVVEIQGEGRVLGFVKDVMPFLRVRKVQLGQGDVVVFSTDGMVEVQNLQ
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
RERFGNERVDRILQESHGLPVSQITRTIYARLCEFMARDMQDDVTVLAIKCLGPR
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
GLLFFSYLFVAVFVFDVFCLKFYTRRAYALLANIALVSGVASFFLSLSLTAVLYGKMNI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAFLFKIALIFFTHASYLFSDMAYQLPYFKKNKRFFLCNTTIHLFGILIIIFGMGPFKWN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCHHHHHHHHHHHHCCCCEEEE
VLVSFKFYQNYLFSSVSGIVLYAALFFLIIPCVTFATLVKKAFMMKSIAYRQQLLFLAGA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALGFITWVIILFLFAVFPWVFVFFPLGGVFIVLFSQWAFASTGIVSFKEVVFALSRFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
CTVGFSCTAGYISVFWVHRFSTLDMQFVFGFFIVYALFALRDYAFDACSVFFGEIADSGQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KLAAELQALDYTAKPAQVLRTFMDTLRMRIACRGLTFLLADEAGVFKTVYSDFEEMATHE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHHHHHH
MEHQSLQYFFNQDVLMIRKSDPVIDHARQAIRTDILHFFDITHAQMIVLIREAQKLIGCL
HHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CFGMKNNGVEYSNHDQHVLEKLYSHFVLVSYYLQNIAKQDVVITVDKELKMSHQIIESIQ
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHH
RKRDFIQDASVEVDSIAYSAHQLGGDFVDFIKLSEKRYLLVIGDVSGKGLAASMSMVILK
HHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
SVLSTFLRGLCLEETAVFTTFIEKINRFIKDNLPCGTFFAGVFCILDLATHTLYYANCGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCH
PLMSMYVASYKNVVEIQGEGRVLGFVKDVMPFLRVRKVQLGQGDVVVFSTDGMVEVQNLQ
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHH
RERFGNERVDRILQESHGLPVSQITRTIYARLCEFMARDMQDDVTVLAIKCLGPR
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]