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The map label for this gene is thiP [H]

Identifier: 189025377

GI number: 189025377

Start: 164231

End: 166012

Strand: Reverse

Name: thiP [H]

Synonym: TPASS_0143

Alternate gene names: 189025377

Gene position: 166012-164231 (Counterclockwise)

Preceding gene: 189025378

Following gene: 189025376

Centisome position: 14.57

GC content: 53.2

Gene sequence:

>1782_bases
GTGCCGCGCTGCAGCAGCGGCATTACACGCATCAACCCCATGACCACGCTCTTACATCCGTGCCGCCGCTCGTGTGCGTC
TGGAGCTCTCTATCTGACAAGAGGAAGGGACGCGCGCAACTACTGTGTTGCTCTCATCTGTGCGTTGTGCTTCTCGCTGA
GTATAGGCACATTCCTTATCCCCGTGTTCACGGCGGGAAGCGCCTTTTTCTCTAAACCGAGATTAGAAAACACTGCGGCA
CATCCCTCACCGGGAACTTTGCAGACAGGTTCCCCCATCACTCCTTTCTTCCTCCCTCCCGGCACGCCTGGTGCCGCACG
CTTTGGGGCACTGTTCGCGCAGAGCGTTTTTCAAGCACTCTGCTCAGCGGTGCTCGCGTGCGCAGTAGGTTTTGGTGCCG
CGTTTTTTTTTGTAAAACGCTCCCTTCGCGCGCGGGCGCTTTTTCCTGCACTCTGTGCCATACCACTTGCCATCCCGCCC
TTAACCATGGCGCTGGCATTTCTTCTTTCCTTCGGGAAAAATGGTTTGTGCACGCGTACGCTCGGCACACTCTGGGGTGT
CTCTACGCCACGCACCTTTTTATATTCTGCCTCTGGCGTGGTGATTGCGCACGCCTGGTATAATTTTCCCCTCGCACTCG
CTATCATCGCTAGAGCCTGGAATACCATCTCCGCAGACGCTGAAGACGCCGCGCGCCTGTTAGGCGCGCGCGCGTATAGA
GTTTTCTATACCATCACCCTTCCTGCACTCGCCGGCGCACTGCGTTCTTCCTTTCTTGTTATTTTTTTGTACTGCTTTTT
CAGCCTCATGATGGTGCTCTTACTCGGCGGCACAACGTTCACCACGTTGGAAGTGGAGCTCTATCGCAGTATACGAACAC
AGGCTGCACACCCCTACGCGAGTACCCTCGCACTGAGTCAGACGTTTTACGCACTGCTTATGATCTGGGGCGTTTCCACA
GAAGAATCGCAGCAGGCGCAGTCGTGCGTAGCGCGCACACGCCCTCTGCCCACACAAAGCATACAGGGAAACATTGAGCG
CATAGGATTTTTTGCACTGCTGTGCGGAATTCTTTTTTTTCTCATTCTCCCTCTTTTTTCTCTTGTTCTTCACTCAATAA
CGCGCCACCGTGCAGGAAGGACCGTATCGTTCACCCTCACTGCATGGCACACCCTTTTTTCTGCGCCATCGTTCTGGCAT
GCGCTGCGCAGCACCATATGGATCGGCTTTTGGAGTTTTTGCGTCACTGTCGGTAGCGTGCTGTGTTACGGATATATGGT
ACTCATGCGACACGTTTCCAGATGGAAAACACGCCTACCCTTTCTACCCCTCGCAGTTTCTCCTATGGTGCTCGCCTTTG
GCTGGTCGCTCATGCCGCGGTGTGCTTCGCGCATACTCTTGGTGTGTGCCCAAAGTGCACTTGCATTTCCCTTCGCATGG
TTGTCACTGTACTCAACGCTCATGCGCATTCCTACACCTGTTATTTTTACAGGACAGATGTTGTCGCGCAACCGACTAGA
TTTTTTCTTACGTACTATATGCCCCTTGTGTAAAAAAGGAATTGTAAGTGCTGGCGTATACGCCTTTGCACTCAGTGCGG
CGGACGCTGCATTTCCGCTCGTGTTAGAAATTCCTGACTTTCAAAGCGTAGCATTACTGCTTTACCGTCTCTCGAGCACA
TACCGTTTTGCAGAAAGCTCTGCGCTTGCTCTGGTGCTATCGCTTGCAAGCAGCGTGCTTTTAATAGGCGTACACCGATG
TAAGGAATACTCCTATGGATAA

Upstream 100 bases:

>100_bases
TCACTCAGTGGATGTACCCGGCCAATCCTGACGTACCGTTGCCTGCCGCATTCTCTGCAGTCCCTCAACCTGCTGCCTGC
GTGTCTCTCTCGCCGCAGAT

Downstream 100 bases:

>100_bases
TAGGCCGTACGTAGTAGTACAAGAACTGACAAAAGTATGGGAAGAAAAAAGGATCAGCCTGTCTTTCTCGCTGAGGCAAG
GCACATCGCTCGCACTGTTA

Product: thiamine ABC transporter permease

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 592

Protein sequence:

>593_residues
MPRCSSGITRINPMTTLLHPCRRSCASGALYLTRGRDARNYCVALICALCFSLSIGTFLIPVFTAGSAFFSKPRLENTAA
HPSPGTLQTGSPITPFFLPPGTPGAARFGALFAQSVFQALCSAVLACAVGFGAAFFFVKRSLRARALFPALCAIPLAIPP
LTMALAFLLSFGKNGLCTRTLGTLWGVSTPRTFLYSASGVVIAHAWYNFPLALAIIARAWNTISADAEDAARLLGARAYR
VFYTITLPALAGALRSSFLVIFLYCFFSLMMVLLLGGTTFTTLEVELYRSIRTQAAHPYASTLALSQTFYALLMIWGVST
EESQQAQSCVARTRPLPTQSIQGNIERIGFFALLCGILFFLILPLFSLVLHSITRHRAGRTVSFTLTAWHTLFSAPSFWH
ALRSTIWIGFWSFCVTVGSVLCYGYMVLMRHVSRWKTRLPFLPLAVSPMVLAFGWSLMPRCASRILLVCAQSALAFPFAW
LSLYSTLMRIPTPVIFTGQMLSRNRLDFFLRTICPLCKKGIVSAGVYAFALSAADAAFPLVLEIPDFQSVALLLYRLSST
YRFAESSALALVLSLASSVLLIGVHRCKEYSYG

Sequences:

>Translated_593_residues
MPRCSSGITRINPMTTLLHPCRRSCASGALYLTRGRDARNYCVALICALCFSLSIGTFLIPVFTAGSAFFSKPRLENTAA
HPSPGTLQTGSPITPFFLPPGTPGAARFGALFAQSVFQALCSAVLACAVGFGAAFFFVKRSLRARALFPALCAIPLAIPP
LTMALAFLLSFGKNGLCTRTLGTLWGVSTPRTFLYSASGVVIAHAWYNFPLALAIIARAWNTISADAEDAARLLGARAYR
VFYTITLPALAGALRSSFLVIFLYCFFSLMMVLLLGGTTFTTLEVELYRSIRTQAAHPYASTLALSQTFYALLMIWGVST
EESQQAQSCVARTRPLPTQSIQGNIERIGFFALLCGILFFLILPLFSLVLHSITRHRAGRTVSFTLTAWHTLFSAPSFWH
ALRSTIWIGFWSFCVTVGSVLCYGYMVLMRHVSRWKTRLPFLPLAVSPMVLAFGWSLMPRCASRILLVCAQSALAFPFAW
LSLYSTLMRIPTPVIFTGQMLSRNRLDFFLRTICPLCKKGIVSAGVYAFALSAADAAFPLVLEIPDFQSVALLLYRLSST
YRFAESSALALVLSLASSVLLIGVHRCKEYSYG
>Mature_592_residues
PRCSSGITRINPMTTLLHPCRRSCASGALYLTRGRDARNYCVALICALCFSLSIGTFLIPVFTAGSAFFSKPRLENTAAH
PSPGTLQTGSPITPFFLPPGTPGAARFGALFAQSVFQALCSAVLACAVGFGAAFFFVKRSLRARALFPALCAIPLAIPPL
TMALAFLLSFGKNGLCTRTLGTLWGVSTPRTFLYSASGVVIAHAWYNFPLALAIIARAWNTISADAEDAARLLGARAYRV
FYTITLPALAGALRSSFLVIFLYCFFSLMMVLLLGGTTFTTLEVELYRSIRTQAAHPYASTLALSQTFYALLMIWGVSTE
ESQQAQSCVARTRPLPTQSIQGNIERIGFFALLCGILFFLILPLFSLVLHSITRHRAGRTVSFTLTAWHTLFSAPSFWHA
LRSTIWIGFWSFCVTVGSVLCYGYMVLMRHVSRWKTRLPFLPLAVSPMVLAFGWSLMPRCASRILLVCAQSALAFPFAWL
SLYSTLMRIPTPVIFTGQMLSRNRLDFFLRTICPLCKKGIVSAGVYAFALSAADAAFPLVLEIPDFQSVALLLYRLSSTY
RFAESSALALVLSLASSVLLIGVHRCKEYSYG

Specific function: Part of the ABC transporter complex thiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1178

COG function: function code P; ABC-type Fe3+ transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transmembrane type-1 domains [H]

Homologues:

Organism=Escherichia coli, GI1786254, Length=198, Percent_Identity=29.7979797979798, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005947 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 64883; Mature: 64752

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRCSSGITRINPMTTLLHPCRRSCASGALYLTRGRDARNYCVALICALCFSLSIGTFLI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
PVFTAGSAFFSKPRLENTAAHPSPGTLQTGSPITPFFLPPGTPGAARFGALFAQSVFQAL
HHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
CSAVLACAVGFGAAFFFVKRSLRARALFPALCAIPLAIPPLTMALAFLLSFGKNGLCTRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
LGTLWGVSTPRTFLYSASGVVIAHAWYNFPLALAIIARAWNTISADAEDAARLLGARAYR
HHHHHCCCCCHHHHEECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VFYTITLPALAGALRSSFLVIFLYCFFSLMMVLLLGGTTFTTLEVELYRSIRTQAAHPYA
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHH
STLALSQTFYALLMIWGVSTEESQQAQSCVARTRPLPTQSIQGNIERIGFFALLCGILFF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHH
LILPLFSLVLHSITRHRAGRTVSFTLTAWHTLFSAPSFWHALRSTIWIGFWSFCVTVGSV
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LCYGYMVLMRHVSRWKTRLPFLPLAVSPMVLAFGWSLMPRCASRILLVCAQSALAFPFAW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLYSTLMRIPTPVIFTGQMLSRNRLDFFLRTICPLCKKGIVSAGVYAFALSAADAAFPL
HHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLEIPDFQSVALLLYRLSSTYRFAESSALALVLSLASSVLLIGVHRCKEYSYG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PRCSSGITRINPMTTLLHPCRRSCASGALYLTRGRDARNYCVALICALCFSLSIGTFLI
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
PVFTAGSAFFSKPRLENTAAHPSPGTLQTGSPITPFFLPPGTPGAARFGALFAQSVFQAL
HHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
CSAVLACAVGFGAAFFFVKRSLRARALFPALCAIPLAIPPLTMALAFLLSFGKNGLCTRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
LGTLWGVSTPRTFLYSASGVVIAHAWYNFPLALAIIARAWNTISADAEDAARLLGARAYR
HHHHHCCCCCHHHHEECCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VFYTITLPALAGALRSSFLVIFLYCFFSLMMVLLLGGTTFTTLEVELYRSIRTQAAHPYA
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHH
STLALSQTFYALLMIWGVSTEESQQAQSCVARTRPLPTQSIQGNIERIGFFALLCGILFF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHH
LILPLFSLVLHSITRHRAGRTVSFTLTAWHTLFSAPSFWHALRSTIWIGFWSFCVTVGSV
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LCYGYMVLMRHVSRWKTRLPFLPLAVSPMVLAFGWSLMPRCASRILLVCAQSALAFPFAW
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLYSTLMRIPTPVIFTGQMLSRNRLDFFLRTICPLCKKGIVSAGVYAFALSAADAAFPL
HHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VLEIPDFQSVALLLYRLSSTYRFAESSALALVLSLASSVLLIGVHRCKEYSYG
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA