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The map label for this gene is pepC [H]

Identifier: 189025346

GI number: 189025346

Start: 128395

End: 129747

Strand: Reverse

Name: pepC [H]

Synonym: TPASS_0112

Alternate gene names: 189025346

Gene position: 129747-128395 (Counterclockwise)

Preceding gene: 189025349

Following gene: 189025343

Centisome position: 11.39

GC content: 46.86

Gene sequence:

>1353_bases
ATGTATCTTACAAAGGAACTACTCGATACGTTTGCGCACGAAGTCGCCGCAGATCCTATACACAAAGCGGTCGCAGGAGC
TGTTGCGCGCGTCGGTCTTGAAGAAGCTGCACTGAACACAGAAGTGGCGCGTCAGCACACACATATTTTTTCTACCGAGA
CAAAACGTGGAGAAATGACCAATCAAAAAATGAGTGGTCGCTGCTGGATATTTGCTGCGCTCAACGCCGCGCGTGTAAAC
ACCATGAAAAAGTTGGACATTGAAACAGTTGAGTTTTCCCAAAACTATCTTTTCTTTTGGGATAAATTGGAGAAAGCAAA
TTTCTTTTTAGAAAATATCCTAGAAACACTTGATGAACCTCTCACCAGTCGGTTGATGGCACACCTGCTTGCAAATCCCG
TCCAAGATGGCGGGCAATGGGATATGTTTTCAGGGTTATTAGAAAAATACGGTCTTGTGCCCAAAGAATGTATGCCTGAA
ACTTTTCACTCTTCCAACTCACGCGTTCTTCTTGCAGTCCTCACTCGTCGGCTGAGGAAGCATGCACAGCTTTTACGTTC
TGCGCATGAAGAAGGCGTTGCGCTGCATACCCTGAGGGAGAAAAAGGAAGCGTTCCTTTCTTCCATCTACTCTATCCTCG
TGAAGGCTCTCGGGAGACCTCCGGAGAAATTCGACTTTGTGTACAAGGATAAGGAAAAAAAATTTCACAAAGTCAGAGAC
CTTACGCCGCAGAAGTTTTTTTGCGATTTCGTCGGATGGGATCTTAAAAACAAAGTGAGTTTGATTCACGCGCCAACTGC
GGATAAACCGTTTGGCAGAGCATACACGGTTAAATTTCTAGGCACCGTAAAGGAAGCCCCGTGCATCTGCTATGTCAATA
CTCCCATTGAAGTGCTCAAAGAAGCTACAGCTTCTGCAATCCGAGCCGGGGAGCCGGTATGGTTTGGTTGTGATGTAGGT
CAAATGATGACGCGCAAAGATGGTATCATGGATACGGAGATATTCGGGTACGAGTCGATGCTCGGCACTACCCCTGAATT
CAATAAAGCAGAACGGCTTGACTATGGCGAAAGTCTTTTAACACACGCGATGGTCATAACCGGTTTTGACGAGGATGCAC
AAGGTAACCCCGTACGCTGGCAGGTAGAAAATTCGTGGGGAGATGACACAGGAAAAAAGGGCATGTTCTCTATGAGCGAT
CGCTGGTTTGACGAATATCTCTACCAAATTACGATCGACAAGAAGTTCGTACCACAGGTGTGGCTCGATGCGCTAGAGAA
GCCAATAATAGCGCTCGAACCTTGGGATCCGATGGGAGCGCTGGCGGACACCCCTCTGTATCTTAAAAATTAA

Upstream 100 bases:

>100_bases
ACGGGAAACATTTTCCTGTGACAACACTCACCGTATTCACACAGACTTCGTTGTAGACAGAATAAAAATTCTCACTCAGT
ATAAAAACACAGGAGGCATG

Downstream 100 bases:

>100_bases
GAAGAAGAACAAGTGCGCAATTCTGATCGGTACTTATTTACGGTACGTCTTGCGCACTTGATGCCCTGCTCACCGAGCAA
CTGGGCTATCCTTCGGTCGG

Product: aminopeptidase C

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MYLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNTEVARQHTHIFSTETKRGEMTNQKMSGRCWIFAALNAARVN
TMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETLDEPLTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKECMPE
TFHSSNSRVLLAVLTRRLRKHAQLLRSAHEEGVALHTLREKKEAFLSSIYSILVKALGRPPEKFDFVYKDKEKKFHKVRD
LTPQKFFCDFVGWDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLKEATASAIRAGEPVWFGCDVG
QMMTRKDGIMDTEIFGYESMLGTTPEFNKAERLDYGESLLTHAMVITGFDEDAQGNPVRWQVENSWGDDTGKKGMFSMSD
RWFDEYLYQITIDKKFVPQVWLDALEKPIIALEPWDPMGALADTPLYLKN

Sequences:

>Translated_450_residues
MYLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNTEVARQHTHIFSTETKRGEMTNQKMSGRCWIFAALNAARVN
TMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETLDEPLTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKECMPE
TFHSSNSRVLLAVLTRRLRKHAQLLRSAHEEGVALHTLREKKEAFLSSIYSILVKALGRPPEKFDFVYKDKEKKFHKVRD
LTPQKFFCDFVGWDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLKEATASAIRAGEPVWFGCDVG
QMMTRKDGIMDTEIFGYESMLGTTPEFNKAERLDYGESLLTHAMVITGFDEDAQGNPVRWQVENSWGDDTGKKGMFSMSD
RWFDEYLYQITIDKKFVPQVWLDALEKPIIALEPWDPMGALADTPLYLKN
>Mature_450_residues
MYLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNTEVARQHTHIFSTETKRGEMTNQKMSGRCWIFAALNAARVN
TMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETLDEPLTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKECMPE
TFHSSNSRVLLAVLTRRLRKHAQLLRSAHEEGVALHTLREKKEAFLSSIYSILVKALGRPPEKFDFVYKDKEKKFHKVRD
LTPQKFFCDFVGWDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLKEATASAIRAGEPVWFGCDVG
QMMTRKDGIMDTEIFGYESMLGTTPEFNKAERLDYGESLLTHAMVITGFDEDAQGNPVRWQVENSWGDDTGKKGMFSMSD
RWFDEYLYQITIDKKFVPQVWLDALEKPIIALEPWDPMGALADTPLYLKN

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=450, Percent_Identity=38.4444444444444, Blast_Score=348, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6324090, Length=449, Percent_Identity=37.4164810690423, Blast_Score=299, Evalue=7e-82,
Organism=Drosophila melanogaster, GI161077632, Length=448, Percent_Identity=36.1607142857143, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24640588, Length=448, Percent_Identity=36.1607142857143, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI161077630, Length=367, Percent_Identity=37.3297002724796, Blast_Score=271, Evalue=6e-73,
Organism=Drosophila melanogaster, GI20130175, Length=423, Percent_Identity=26.7139479905437, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 51243; Mature: 51243

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00139 THIOL_PROTEASE_CYS ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNTEVARQHTHIFSTETKRGEMT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NQKMSGRCWIFAALNAARVNTMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETLDEP
CCCCCCCEEEEEECCHHHHHHHHHCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHH
LTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKECMPETFHSSNSRVLLAVLTRRLRK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHCCCCCEEHHHHHHHHHHH
HAQLLRSAHEEGVALHTLREKKEAFLSSIYSILVKALGRPPEKFDFVYKDKEKKFHKVRD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHC
LTPQKFFCDFVGWDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLK
CCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEHHHHHHCCCCEEEEECCHHHHHH
EATASAIRAGEPVWFGCDVGQMMTRKDGIMDTEIFGYESMLGTTPEFNKAERLDYGESLL
HHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCHHHCHHHHCCCCCCCCCHHHCCHHHHHH
THAMVITGFDEDAQGNPVRWQVENSWGDDTGKKGMFSMSDRWFDEYLYQITIDKKFVPQV
HHHHHEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCHHHHHH
WLDALEKPIIALEPWDPMGALADTPLYLKN
HHHHHCCCEEEECCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MYLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNTEVARQHTHIFSTETKRGEMT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NQKMSGRCWIFAALNAARVNTMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETLDEP
CCCCCCCEEEEEECCHHHHHHHHHCCCEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHH
LTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKECMPETFHSSNSRVLLAVLTRRLRK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHCCCCCEEHHHHHHHHHHH
HAQLLRSAHEEGVALHTLREKKEAFLSSIYSILVKALGRPPEKFDFVYKDKEKKFHKVRD
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHC
LTPQKFFCDFVGWDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLK
CCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEHHHHHHCCCCEEEEECCHHHHHH
EATASAIRAGEPVWFGCDVGQMMTRKDGIMDTEIFGYESMLGTTPEFNKAERLDYGESLL
HHHHHHHHCCCCEEEECCHHHHHHHHCCCCCCHHHCHHHHCCCCCCCCCHHHCCHHHHHH
THAMVITGFDEDAQGNPVRWQVENSWGDDTGKKGMFSMSDRWFDEYLYQITIDKKFVPQV
HHHHHEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCHHHHHH
WLDALEKPIIALEPWDPMGALADTPLYLKN
HHHHHCCCEEEECCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7925365 [H]