The gene/protein map for NC_010741 is currently unavailable.
Definition Treponema pallidum subsp. pallidum SS14, complete genome.
Accession NC_010741
Length 1,139,457

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The map label for this gene is dnaJ1 [H]

Identifier: 189025332

GI number: 189025332

Start: 106716

End: 107366

Strand: Reverse

Name: dnaJ1 [H]

Synonym: TPASS_0098

Alternate gene names: 189025332

Gene position: 107366-106716 (Counterclockwise)

Preceding gene: 189025333

Following gene: 189025330

Centisome position: 9.42

GC content: 60.22

Gene sequence:

>651_bases
ATGAGCGAGCGCACTGTTCCTGACCATTACGCCATACTGGGCGTTGCTGCCGATGCTTCTGAGGAACACATTAAGAAAGC
TTTTCGCGCGCAGGCGCTTAAGTATCATCCGGATAAAAATCCGGGCGACGCGTGTGCGGAGGACCAGTTTAAAAGGATCA
ACGCAGCTTACGCCGTCCTCTCTGACCGTGCATCACGCGCACGCTACGATGCCGAACGCGCAGGTGGCGCATTTTGGTCC
TCGCGTGCAGGACGCGACGCCTCAGAGGGCTTTGGCGCTTGGACCTCCAGGTACGGACGACAAGGCAGGAGCGCGCACCC
GCTACACACACACGCACGGTCCCTGGAGAGGGCACGCGCGGGAAACCGAACACTTCGAGGGATGGTACACTTTCTTCGGT
GGTTTTCCTGGAAATGGGTGGAGTTATTGGAGCAGTGCAGACGCTCCGCCCGATCCGGCGGGTCCTACCGCGCGCACGGG
CTCCAGGAAAGACGGGGCGCGCCTTCTCATTCAGGGAGCGGCGCTCGTCCTCCTGGCTCTATTCGGGCTACGCTTCTTTT
TAGTATTTGGCTTCTTCGGGATCGCATTCAGCGTGTCCTGCCTGGCGCGCGGAGTGCACACCCTGAGGGCAGGACTCTCA
ATCCTCCTTGA

Upstream 100 bases:

>100_bases
GTCGGGAATTCAGGTCATTTGCGCAACAGGGCGTGACTTACCGAATTTGGAGCGCATCCTGAACAGGCAAGAGTTCGTGG
GGACCACCATTGGGTAAACG

Downstream 100 bases:

>100_bases
AGGATGAGCAACCCCGCTGCTAAAGAGGAGCAAGCACCTCTCTCCTGCGAGAGAGGAATCTAACGCTCACGAAACATAAT
TCTGCCGCGGGAGAGGTCGT

Product: heat-shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSERTVPDHYAILGVAADASEEHIKKAFRAQALKYHPDKNPGDACAEDQFKRINAAYAVLSDRASRARYDAERAGGAFWS
SRAGRDASEGFGAWTSRYGRQGRSAHPLHTHARSLERARAGNRTLRGMVHFLRWFSWKWVELLEQCRRSARSGGSYRAHG
LQERRGAPSHSGSGARPPGSIRATLLFSIWLLRDRIQRVLPGARSAHPEGRTLNPP

Sequences:

>Translated_216_residues
MSERTVPDHYAILGVAADASEEHIKKAFRAQALKYHPDKNPGDACAEDQFKRINAAYAVLSDRASRARYDAERAGGAFWS
SRAGRDASEGFGAWTSRYGRQGRSAHPLHTHARSLERARAGNRTLRGMVHFLRWFSWKWVELLEQCRRSARSGGSYRAHG
LQERRGAPSHSGSGARPPGSIRATLLFSIWLLRDRIQRVLPGARSAHPEGRTLNPP
>Mature_215_residues
SERTVPDHYAILGVAADASEEHIKKAFRAQALKYHPDKNPGDACAEDQFKRINAAYAVLSDRASRARYDAERAGGAFWSS
RAGRDASEGFGAWTSRYGRQGRSAHPLHTHARSLERARAGNRTLRGMVHFLRWFSWKWVELLEQCRRSARSGGSYRAHGL
QERRGAPSHSGSGARPPGSIRATLLFSIWLLRDRIQRVLPGARSAHPEGRTLNPP

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI29126218, Length=87, Percent_Identity=41.3793103448276, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI45504382, Length=87, Percent_Identity=39.0804597701149, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4504511, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI201862518, Length=63, Percent_Identity=55.5555555555556, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI201862587, Length=63, Percent_Identity=55.5555555555556, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI56549115, Length=63, Percent_Identity=55.5555555555556, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI23503241, Length=84, Percent_Identity=51.1904761904762, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI6631085, Length=63, Percent_Identity=55.5555555555556, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI194328760, Length=168, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI72534740, Length=72, Percent_Identity=50, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI194328758, Length=168, Percent_Identity=32.1428571428571, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI68077166, Length=68, Percent_Identity=58.8235294117647, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI68077168, Length=66, Percent_Identity=60.6060606060606, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706495, Length=64, Percent_Identity=51.5625, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI22749377, Length=65, Percent_Identity=56.9230769230769, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI205360838, Length=69, Percent_Identity=47.8260869565217, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI205360840, Length=69, Percent_Identity=47.8260869565217, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI24308127, Length=66, Percent_Identity=48.4848484848485, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5453690, Length=65, Percent_Identity=55.3846153846154, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI4885495, Length=64, Percent_Identity=54.6875, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI17388799, Length=64, Percent_Identity=54.6875, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI194306642, Length=65, Percent_Identity=55.3846153846154, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI194306640, Length=65, Percent_Identity=55.3846153846154, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI27151736, Length=90, Percent_Identity=43.3333333333333, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI8922563, Length=78, Percent_Identity=39.7435897435897, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1786197, Length=63, Percent_Identity=53.968253968254, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554644, Length=114, Percent_Identity=42.1052631578947, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17507263, Length=62, Percent_Identity=54.8387096774194, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534355, Length=63, Percent_Identity=52.3809523809524, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI115532378, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645553, Length=63, Percent_Identity=49.2063492063492, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322194, Length=64, Percent_Identity=46.875, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=61, Percent_Identity=55.7377049180328, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324103, Length=66, Percent_Identity=50, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=63, Percent_Identity=47.6190476190476, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320888, Length=87, Percent_Identity=41.3793103448276, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24668523, Length=87, Percent_Identity=40.2298850574713, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28574723, Length=87, Percent_Identity=40.2298850574713, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI17737735, Length=87, Percent_Identity=40.2298850574713, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI85726398, Length=63, Percent_Identity=53.968253968254, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129487, Length=155, Percent_Identity=34.8387096774194, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584014, Length=155, Percent_Identity=34.8387096774194, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646562, Length=81, Percent_Identity=44.4444444444444, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646560, Length=81, Percent_Identity=44.4444444444444, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646558, Length=81, Percent_Identity=44.4444444444444, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646556, Length=81, Percent_Identity=44.4444444444444, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357547, Length=81, Percent_Identity=44.4444444444444, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18858081, Length=89, Percent_Identity=41.5730337078652, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658562, Length=63, Percent_Identity=53.968253968254, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658555, Length=63, Percent_Identity=53.968253968254, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641698, Length=64, Percent_Identity=48.4375, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24641696, Length=64, Percent_Identity=48.4375, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 24122; Mature: 23991

Theoretical pI: Translated: 11.55; Mature: 11.55

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSERTVPDHYAILGVAADASEEHIKKAFRAQALKYHPDKNPGDACAEDQFKRINAAYAVL
CCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SDRASRARYDAERAGGAFWSSRAGRDASEGFGAWTSRYGRQGRSAHPLHTHARSLERARA
HHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GNRTLRGMVHFLRWFSWKWVELLEQCRRSARSGGSYRAHGLQERRGAPSHSGSGARPPGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCH
IRATLLFSIWLLRDRIQRVLPGARSAHPEGRTLNPP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SERTVPDHYAILGVAADASEEHIKKAFRAQALKYHPDKNPGDACAEDQFKRINAAYAVL
CCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
SDRASRARYDAERAGGAFWSSRAGRDASEGFGAWTSRYGRQGRSAHPLHTHARSLERARA
HHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
GNRTLRGMVHFLRWFSWKWVELLEQCRRSARSGGSYRAHGLQERRGAPSHSGSGARPPGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCH
IRATLLFSIWLLRDRIQRVLPGARSAHPEGRTLNPP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA