Click here to switch to the map view.

The map label for this gene is yhdH [H]

Identifier: 189025257

GI number: 189025257

Start: 27554

End: 28885

Strand: Direct

Name: yhdH [H]

Synonym: TPASS_0023

Alternate gene names: 189025257

Gene position: 27554-28885 (Clockwise)

Preceding gene: 189025256

Following gene: 189025258

Centisome position: 2.42

GC content: 47.45

Gene sequence:

>1332_bases
ATGAGTCGTAGGAAACAGGGACGAGAGTTATTCAACAGTCATGTGGGCGTGGTGTTGTCTTGTGTCGGTGCGGCAATGGG
GCTTGCAAACGTGTGGTTGTTCCCTGGACGCCTGGTGGAATTTGGTGGTGTGACGTTTTTAATTCCGTATTTTATTTTTC
TATTTGGTCTTTCCCGTTTTGGACTGATGGGGGAGTATGCTTTTGGAAAGACACTGCGCTGCGGTCCTGTGCGTGCGTTT
ACCCGTGTGTGTGAAACACATCCATCGTGTTTTTTACGAGCACTACGAGGTAGCGGGTGGTTTCCGGTAGGAGTATTGCT
CGCTACCTGCTCTTTTTATGTAGTGATTATAGGGTGGATCTTGCGTTATGTAGTATTTTCGTGCACGAATGCACTTGCAG
GTACTCAGGCGCACGACCTGTTTTACCAGGTTGCAGGGACAAGTGCGAATGTGCCGTGGACGCTTGCAGCTATCGCGCTC
ACAGCGTGTGTAGTGAGTGCGGGCGTGCAAAAGGGGGTGGAGCGAGGAAACATTATAATGATGGTACTTTTTTACGGTGT
CCTTGCGTTTATTACAGGATATATATTTACTCTTCCTAACGCGTGGATAGGTATGCGTAGAATGTTGGCATTTCAATCTT
CATCATTGTGCAATCCGAGACTCTGGTTGTATGCATTAGGCATGTCGTTTTTTAGTCTCAGTTTGGGGGGCGCGGCTATG
GTTTTATATGGCAGTTACATGCCAGATACGGTGGACATACCGCGTACTGCATTTCAGACAGCGACCTTAGATTTTTTGGC
ATCAGGTATGTCCGCATTATGTTTAATTCCGAGTGCGTGGGTTTTAGGTATGGACGTCAGCAGTGGACCGGAGTTTTTGT
TTGTAACAATAACCCGTGTCGCCTCGCAGATACCGATGGGGGTGATGATAAGTGTGTTATTCTTTTTGTGTGTACTATGT
GCAGCGTTAAGTTCTGCAATTGCTATGTTAGAAGTAATACTCGAGTCTTTTGTGCACACGTGTACAGTGGGGCGCCGAAC
GCTGACGTGGTCACTAGCACTCGTGGTTGCGTTTGTATCTCTTCCTCTGAATGCCTCGATGAGAGTGTTCGAAACGTTTA
CAGATATAGTGGTGGTTATACTATCTCCGTTATCTGCCCTTATGGGGAGCGTGATGATATTTTGGGTATATGGTGCAGAG
CGTTGCCGTGTAGCTATCAACCGGTGTGCACGCGGTCCGTTGGGTAAATGGTTCACGCCGTATATGCGGTACGTGTATTT
GGGGCTTTGTGTAATGATTATGGTGCTTGGGGTAATGTTCGGTGGTTTTTAG

Upstream 100 bases:

>100_bases
GTCCAGGATAGTGCTACTGAAAAATTCTATTTTTTCTTGAGTCTGTTCTGAAGGGGATCCTTTTGTCTCTTGTAAAAAGG
AATAGACGAGCGGGTAGGAT

Downstream 100 bases:

>100_bases
TGTGATGACGCGCAAAAGCGGCCAAACCCACAGTTGGGTAAATATATTCTTTGCAAATTGTCGACACAACCGTTGACGAG
AGGGATCGCAGGTGGAGAGG

Product: sodium- and chloride- dependent transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSRRKQGRELFNSHVGVVLSCVGAAMGLANVWLFPGRLVEFGGVTFLIPYFIFLFGLSRFGLMGEYAFGKTLRCGPVRAF
TRVCETHPSCFLRALRGSGWFPVGVLLATCSFYVVIIGWILRYVVFSCTNALAGTQAHDLFYQVAGTSANVPWTLAAIAL
TACVVSAGVQKGVERGNIIMMVLFYGVLAFITGYIFTLPNAWIGMRRMLAFQSSSLCNPRLWLYALGMSFFSLSLGGAAM
VLYGSYMPDTVDIPRTAFQTATLDFLASGMSALCLIPSAWVLGMDVSSGPEFLFVTITRVASQIPMGVMISVLFFLCVLC
AALSSAIAMLEVILESFVHTCTVGRRTLTWSLALVVAFVSLPLNASMRVFETFTDIVVVILSPLSALMGSVMIFWVYGAE
RCRVAINRCARGPLGKWFTPYMRYVYLGLCVMIMVLGVMFGGF

Sequences:

>Translated_443_residues
MSRRKQGRELFNSHVGVVLSCVGAAMGLANVWLFPGRLVEFGGVTFLIPYFIFLFGLSRFGLMGEYAFGKTLRCGPVRAF
TRVCETHPSCFLRALRGSGWFPVGVLLATCSFYVVIIGWILRYVVFSCTNALAGTQAHDLFYQVAGTSANVPWTLAAIAL
TACVVSAGVQKGVERGNIIMMVLFYGVLAFITGYIFTLPNAWIGMRRMLAFQSSSLCNPRLWLYALGMSFFSLSLGGAAM
VLYGSYMPDTVDIPRTAFQTATLDFLASGMSALCLIPSAWVLGMDVSSGPEFLFVTITRVASQIPMGVMISVLFFLCVLC
AALSSAIAMLEVILESFVHTCTVGRRTLTWSLALVVAFVSLPLNASMRVFETFTDIVVVILSPLSALMGSVMIFWVYGAE
RCRVAINRCARGPLGKWFTPYMRYVYLGLCVMIMVLGVMFGGF
>Mature_442_residues
SRRKQGRELFNSHVGVVLSCVGAAMGLANVWLFPGRLVEFGGVTFLIPYFIFLFGLSRFGLMGEYAFGKTLRCGPVRAFT
RVCETHPSCFLRALRGSGWFPVGVLLATCSFYVVIIGWILRYVVFSCTNALAGTQAHDLFYQVAGTSANVPWTLAAIALT
ACVVSAGVQKGVERGNIIMMVLFYGVLAFITGYIFTLPNAWIGMRRMLAFQSSSLCNPRLWLYALGMSFFSLSLGGAAMV
LYGSYMPDTVDIPRTAFQTATLDFLASGMSALCLIPSAWVLGMDVSSGPEFLFVTITRVASQIPMGVMISVLFFLCVLCA
ALSSAIAMLEVILESFVHTCTVGRRTLTWSLALVVAFVSLPLNASMRVFETFTDIVVVILSPLSALMGSVMIFWVYGAER
CRVAINRCARGPLGKWFTPYMRYVYLGLCVMIMVLGVMFGGF

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI4507043, Length=467, Percent_Identity=25.2676659528908, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI194018524, Length=295, Percent_Identity=28.135593220339, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI197276623, Length=390, Percent_Identity=23.5897435897436, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI54607094, Length=390, Percent_Identity=23.5897435897436, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554804, Length=454, Percent_Identity=24.4493392070485, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19921936, Length=462, Percent_Identity=25.5411255411255, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24762620, Length=467, Percent_Identity=24.4111349036403, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221329674, Length=396, Percent_Identity=25, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24639514, Length=396, Percent_Identity=25, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 48427; Mature: 48295

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRRKQGRELFNSHVGVVLSCVGAAMGLANVWLFPGRLVEFGGVTFLIPYFIFLFGLSRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHH
GLMGEYAFGKTLRCGPVRAFTRVCETHPSCFLRALRGSGWFPVGVLLATCSFYVVIIGWI
CCCCCHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LRYVVFSCTNALAGTQAHDLFYQVAGTSANVPWTLAAIALTACVVSAGVQKGVERGNIIM
HHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
MVLFYGVLAFITGYIFTLPNAWIGMRRMLAFQSSSLCNPRLWLYALGMSFFSLSLGGAAM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHE
VLYGSYMPDTVDIPRTAFQTATLDFLASGMSALCLIPSAWVLGMDVSSGPEFLFVTITRV
EEECCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHEEECCCCCCCCEEEEEHHHH
ASQIPMGVMISVLFFLCVLCAALSSAIAMLEVILESFVHTCTVGRRTLTWSLALVVAFVS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LPLNASMRVFETFTDIVVVILSPLSALMGSVMIFWVYGAERCRVAINRCARGPLGKWFTP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHH
YMRYVYLGLCVMIMVLGVMFGGF
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]