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The map label for this gene is walR [H]

Identifier: 188587493

GI number: 188587493

Start: 3135683

End: 3136387

Strand: Reverse

Name: walR [H]

Synonym: Nther_2903

Alternate gene names: 188587493

Gene position: 3136387-3135683 (Counterclockwise)

Preceding gene: 188587494

Following gene: 188587492

Centisome position: 99.08

GC content: 38.01

Gene sequence:

>705_bases
ATGAGTTACAGAGTTTTAATTGTAGAAGATGAACAACCTATAGCTGATATCATTAATTTCAATCTTGTCAAAGAAGGGTA
TGAAACAGAGGTCGCCTATAATGGTGAAGATGGATTAGAGAAGTTTGCCAGCTTTTCTCCACACATAATAGTTTTAGACC
TGATGTTACCTGGAAAAGATGGTTTTTCAGTTTGTAAGGAGATTCGCTCCCAAAGTTCGGTTCCCATTTTAGTATTAACA
GCCAAGGATTCGGAAGTTGATAAGGTGTTGGGATTAGAATTGGGAGCAGATGATTACGTTACTAAGCCCTTTGGAAACAG
AGAACTGTTAGCCAGGATTAAGGCCTTACTCCGAAGAGTCAATTTATCTGGGCAAGATTCTTCAAGTAGTGAAAAAGATG
AGGATATTTTGAAGTATAACGATGTTGAAATAAATCTAAAAACTGCTGAAGTAAAAAAACAGGGGCAAGCCATAGATCTG
ACTTATCGGGAATTTCAATTATTCGTTTATTTAGTCAAACGACAAGGAGAAGTAATTTCTCGGGAACGGATGATTGAAGA
AGTCTGGGGATACGACTTTATTGGGGAAGACCGTACCGTTGATGTTACCATTAGGCGCTTAAGAGAGAAATTAGAAGATG
ATCCAGGGAGCCCAAGCTATATAATGACTAAAAGAGGTATGGGTTATTACCTTAGGAGGACTTAA

Upstream 100 bases:

>100_bases
TTTTTTATGTAATTTTATCCTTTTATATATGAGCAGGAATTGTTTAGTTAAGAGCGAAATAATGTATAAAAGTAATAATT
ATGTTAAGCAGGTGAATTAA

Downstream 100 bases:

>100_bases
TATGTTTAAAACAGTCCAGTGGAAACTGGTTGTTATATATCTATTACTGGTGCTATTAGCCATGGAGCTAATTAGTGTTT
ATCTATTACAGTCACTTGAT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSYRVLIVEDEQPIADIINFNLVKEGYETEVAYNGEDGLEKFASFSPHIIVLDLMLPGKDGFSVCKEIRSQSSVPILVLT
AKDSEVDKVLGLELGADDYVTKPFGNRELLARIKALLRRVNLSGQDSSSSEKDEDILKYNDVEINLKTAEVKKQGQAIDL
TYREFQLFVYLVKRQGEVISRERMIEEVWGYDFIGEDRTVDVTIRRLREKLEDDPGSPSYIMTKRGMGYYLRRT

Sequences:

>Translated_234_residues
MSYRVLIVEDEQPIADIINFNLVKEGYETEVAYNGEDGLEKFASFSPHIIVLDLMLPGKDGFSVCKEIRSQSSVPILVLT
AKDSEVDKVLGLELGADDYVTKPFGNRELLARIKALLRRVNLSGQDSSSSEKDEDILKYNDVEINLKTAEVKKQGQAIDL
TYREFQLFVYLVKRQGEVISRERMIEEVWGYDFIGEDRTVDVTIRRLREKLEDDPGSPSYIMTKRGMGYYLRRT
>Mature_233_residues
SYRVLIVEDEQPIADIINFNLVKEGYETEVAYNGEDGLEKFASFSPHIIVLDLMLPGKDGFSVCKEIRSQSSVPILVLTA
KDSEVDKVLGLELGADDYVTKPFGNRELLARIKALLRRVNLSGQDSSSSEKDEDILKYNDVEINLKTAEVKKQGQAIDLT
YREFQLFVYLVKRQGEVISRERMIEEVWGYDFIGEDRTVDVTIRRLREKLEDDPGSPSYIMTKRGMGYYLRRT

Specific function: Member of the two-component regulatory system walK/walR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=38.4279475982533, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=40.174672489083, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=36.6379310344828, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=37.6106194690265, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=35.1111111111111, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=38.2608695652174, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=35.6828193832599, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=36.2445414847162, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=37.280701754386, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=34.4827586206897, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=34.9344978165939, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=30.7017543859649, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=32.3144104803493, Blast_Score=117, Evalue=4e-28,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.4561403508772, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=36.4485981308411, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787487, Length=150, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=29.7297297297297, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26789; Mature: 26658

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRVLIVEDEQPIADIINFNLVKEGYETEVAYNGEDGLEKFASFSPHIIVLDLMLPGKD
CCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCEEEEEEEECCCC
GFSVCKEIRSQSSVPILVLTAKDSEVDKVLGLELGADDYVTKPFGNRELLARIKALLRRV
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHEEECCCCCEECCCCCHHHHHHHHHHHHHC
NLSGQDSSSSEKDEDILKYNDVEINLKTAEVKKQGQAIDLTYREFQLFVYLVKRQGEVIS
CCCCCCCCCCCCCCHHHEECCEEEEEEHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCHHH
RERMIEEVWGYDFIGEDRTVDVTIRRLREKLEDDPGSPSYIMTKRGMGYYLRRT
HHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECC
>Mature Secondary Structure 
SYRVLIVEDEQPIADIINFNLVKEGYETEVAYNGEDGLEKFASFSPHIIVLDLMLPGKD
CEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCEEEEEEEECCCC
GFSVCKEIRSQSSVPILVLTAKDSEVDKVLGLELGADDYVTKPFGNRELLARIKALLRRV
HHHHHHHHHCCCCCCEEEEEECCCCHHHHHHEEECCCCCEECCCCCHHHHHHHHHHHHHC
NLSGQDSSSSEKDEDILKYNDVEINLKTAEVKKQGQAIDLTYREFQLFVYLVKRQGEVIS
CCCCCCCCCCCCCCHHHEECCEEEEEEHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCHHH
RERMIEEVWGYDFIGEDRTVDVTIRRLREKLEDDPGSPSYIMTKRGMGYYLRRT
HHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA