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The map label for this gene is yycG [H]

Identifier: 188587492

GI number: 188587492

Start: 3133843

End: 3135681

Strand: Reverse

Name: yycG [H]

Synonym: Nther_2902

Alternate gene names: 188587492

Gene position: 3135681-3133843 (Counterclockwise)

Preceding gene: 188587493

Following gene: 188587491

Centisome position: 99.06

GC content: 37.52

Gene sequence:

>1839_bases
ATGTTTAAAACAGTCCAGTGGAAACTGGTTGTTATATATCTATTACTGGTGCTATTAGCCATGGAGCTAATTAGTGTTTA
TCTATTACAGTCACTTGATCAATACTATCTAGATGATTATAGTGAACGTATGTCAACAGAAGCCGAACTAGCAAAAAGCT
TGCTGCAAAGGCACATGACCGAAGAACAAGATGCTGATCAAATTTCTCAATTGCTCGGGGAGTTTGGCCAGCAAGCTCAT
AATGAGATTACAATATTAGATGAAAATGGTAGAGTCCTGGCTACTTCCTCGGGCGAGGAAGAACTTCAAGGAAATATTAT
TGTGGAAGAAGAAATTACTAGAGCCCTAGCTGGGAGTCAAGGGAGTAATATTAGAATAAATCCAAATACAAATATTCGAC
AAAAATCCCTTGCAATTCCTATAGAAAGCGGGAACCAAGTAATAGGAGCTGTTTATTTGGTAGGTTCATTAGAACGTGTT
GATAATACATTGAGTGAAATTAGAACTATTTTATTTACAGGGACACTTTTCGCCATGCTTGTAACAGCTCTCCTAGGGAT
TATCTTATCTAAGACGATAACTAAGCCTGTGAAAGTAGTTACAAGGACAGCTCAGGCTATGGCCCAAGGTGATTTTAATC
AACGTATCGATGTAAAAAGTGATGATGAAATCGGGAATCTTGGTCGAATGTTTAACCATTTAGCCTCTCGCTTGGACTCG
ACTTTGAAAGAAATTTCGTCAGAAAAAGGGAAAATTGAAGCTATCCTAACACAAATGAGTGACGGAGTTATTGCTGTTAA
TAGCAATAAGGAAATAATTCATATTAATCCAGCTGCGGAAAGAATGTTAAATGTTGAAAGAGAAAAGTTACGAGGTCAGT
GCGCCAAAGAGTTACTATCTAAGTTTTTTACTGATGAAGAATTTGATCAAATACTGAAAGGTGAAACAAATGTTAAGGAA
GAAAAAAACCTGACAACAAATGAAGATATGGTGGTGAGAGCACAATTAGTCCCCTTTAAATCTGAAGAAAAACAATACGA
AGGAGTCATCATTGCTTTAAATGATATAACGGAGCAGGAAAAATTGATTCAAATGCGCCAAGAATTTGTAGCCAATGTTT
CTCATGAACTTCGAACTCCTTTAACCTCAGTTAAGAGCTATGTGGAGACTCTTTTAGATGGTGCCCACAAGGATGATGAG
ATTGCTCCACGGTTCTTAAAAGTAGTGCAACAAGAGACAGATCGAATGGTAACTATGGTGAAAGATCTGCTAGTATTGTC
CCAGCTTGACAGGAAGGAGCCTATTATAGAATGTAGAGATATTAATTTTATGGATGTACTTGATAGAAGTATATCTGCAA
TTGAATCACTTACAAAAGATCAAAAAATAGAACTGCATTTAGATTATAAAAGTTTAGAAGGAGAGTATATTGACGTCTTT
AATGAAAAACCTGAATTTATCAGGATTTCTGGGGATTCAGATAAACTGACTCAGGTATTTACAAATATATTAGAAAACGC
AATTAAATACAGTCCTTCTGGTGAATGGATTCAAATCACCGTTGAAGATTATTATGAAAACATTAAAATTTCAGTGAAAG
ACAATGGTATGGGTATCCCGGCTGAAGATTTACCCCGGATCTTTGAACGGTTTTACCGGGTGGAAAAGGCTCGCTCTAGG
GCCCGGGGAGGAAGTGGCCTCGGCCTGGCTATTTCCCGGGAAATAATCAGAAATCATGGTGGAGACATTAACGTATCCAG
TCAAGAGGGAAGGGGAACGGAAGTGATCGTTTATCTCCCGAAAAATCAGGAGGTTCAATATGAATTGGGAGCAAATTAA

Upstream 100 bases:

>100_bases
ACCATTAGGCGCTTAAGAGAGAAATTAGAAGATGATCCAGGGAGCCCAAGCTATATAATGACTAAAAGAGGTATGGGTTA
TTACCTTAGGAGGACTTAAT

Downstream 100 bases:

>100_bases
AACTGTATTGTTAGTTATATTAGTCATAAATAGTATTTTCCTTACTAGTCGTCTTTGGGTCACGGATTATCACTATGAAA
GGTCTGAAGAACCAAATATA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MFKTVQWKLVVIYLLLVLLAMELISVYLLQSLDQYYLDDYSERMSTEAELAKSLLQRHMTEEQDADQISQLLGEFGQQAH
NEITILDENGRVLATSSGEEELQGNIIVEEEITRALAGSQGSNIRINPNTNIRQKSLAIPIESGNQVIGAVYLVGSLERV
DNTLSEIRTILFTGTLFAMLVTALLGIILSKTITKPVKVVTRTAQAMAQGDFNQRIDVKSDDEIGNLGRMFNHLASRLDS
TLKEISSEKGKIEAILTQMSDGVIAVNSNKEIIHINPAAERMLNVEREKLRGQCAKELLSKFFTDEEFDQILKGETNVKE
EKNLTTNEDMVVRAQLVPFKSEEKQYEGVIIALNDITEQEKLIQMRQEFVANVSHELRTPLTSVKSYVETLLDGAHKDDE
IAPRFLKVVQQETDRMVTMVKDLLVLSQLDRKEPIIECRDINFMDVLDRSISAIESLTKDQKIELHLDYKSLEGEYIDVF
NEKPEFIRISGDSDKLTQVFTNILENAIKYSPSGEWIQITVEDYYENIKISVKDNGMGIPAEDLPRIFERFYRVEKARSR
ARGGSGLGLAISREIIRNHGGDINVSSQEGRGTEVIVYLPKNQEVQYELGAN

Sequences:

>Translated_612_residues
MFKTVQWKLVVIYLLLVLLAMELISVYLLQSLDQYYLDDYSERMSTEAELAKSLLQRHMTEEQDADQISQLLGEFGQQAH
NEITILDENGRVLATSSGEEELQGNIIVEEEITRALAGSQGSNIRINPNTNIRQKSLAIPIESGNQVIGAVYLVGSLERV
DNTLSEIRTILFTGTLFAMLVTALLGIILSKTITKPVKVVTRTAQAMAQGDFNQRIDVKSDDEIGNLGRMFNHLASRLDS
TLKEISSEKGKIEAILTQMSDGVIAVNSNKEIIHINPAAERMLNVEREKLRGQCAKELLSKFFTDEEFDQILKGETNVKE
EKNLTTNEDMVVRAQLVPFKSEEKQYEGVIIALNDITEQEKLIQMRQEFVANVSHELRTPLTSVKSYVETLLDGAHKDDE
IAPRFLKVVQQETDRMVTMVKDLLVLSQLDRKEPIIECRDINFMDVLDRSISAIESLTKDQKIELHLDYKSLEGEYIDVF
NEKPEFIRISGDSDKLTQVFTNILENAIKYSPSGEWIQITVEDYYENIKISVKDNGMGIPAEDLPRIFERFYRVEKARSR
ARGGSGLGLAISREIIRNHGGDINVSSQEGRGTEVIVYLPKNQEVQYELGAN
>Mature_612_residues
MFKTVQWKLVVIYLLLVLLAMELISVYLLQSLDQYYLDDYSERMSTEAELAKSLLQRHMTEEQDADQISQLLGEFGQQAH
NEITILDENGRVLATSSGEEELQGNIIVEEEITRALAGSQGSNIRINPNTNIRQKSLAIPIESGNQVIGAVYLVGSLERV
DNTLSEIRTILFTGTLFAMLVTALLGIILSKTITKPVKVVTRTAQAMAQGDFNQRIDVKSDDEIGNLGRMFNHLASRLDS
TLKEISSEKGKIEAILTQMSDGVIAVNSNKEIIHINPAAERMLNVEREKLRGQCAKELLSKFFTDEEFDQILKGETNVKE
EKNLTTNEDMVVRAQLVPFKSEEKQYEGVIIALNDITEQEKLIQMRQEFVANVSHELRTPLTSVKSYVETLLDGAHKDDE
IAPRFLKVVQQETDRMVTMVKDLLVLSQLDRKEPIIECRDINFMDVLDRSISAIESLTKDQKIELHLDYKSLEGEYIDVF
NEKPEFIRISGDSDKLTQVFTNILENAIKYSPSGEWIQITVEDYYENIKISVKDNGMGIPAEDLPRIFERFYRVEKARSR
ARGGSGLGLAISREIIRNHGGDINVSSQEGRGTEVIVYLPKNQEVQYELGAN

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=354, Percent_Identity=29.6610169491525, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=32, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1786783, Length=278, Percent_Identity=31.294964028777, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=31.1475409836066, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1788549, Length=429, Percent_Identity=25.6410256410256, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=249, Percent_Identity=29.3172690763052, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI48994928, Length=271, Percent_Identity=26.9372693726937, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=29.0983606557377, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=28.6290322580645, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790300, Length=378, Percent_Identity=26.7195767195767, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790861, Length=227, Percent_Identity=29.5154185022026, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788713, Length=270, Percent_Identity=24.0740740740741, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789403, Length=249, Percent_Identity=30.1204819277108, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787894, Length=261, Percent_Identity=24.5210727969349, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=271, Percent_Identity=29.520295202952, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=314, Percent_Identity=27.3885350318471, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=235, Percent_Identity=26.3829787234043, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=249, Percent_Identity=24.0963855421687, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787374, Length=251, Percent_Identity=25.0996015936255, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69173; Mature: 69173

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKTVQWKLVVIYLLLVLLAMELISVYLLQSLDQYYLDDYSERMSTEAELAKSLLQRHMT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
EEQDADQISQLLGEFGQQAHNEITILDENGRVLATSSGEEELQGNIIVEEEITRALAGSQ
CCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHCCCEEEHHHHHHHHCCCC
GSNIRINPNTNIRQKSLAIPIESGNQVIGAVYLVGSLERVDNTLSEIRTILFTGTLFAML
CCEEEECCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTALLGIILSKTITKPVKVVTRTAQAMAQGDFNQRIDVKSDDEIGNLGRMFNHLASRLDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TLKEISSEKGKIEAILTQMSDGVIAVNSNKEIIHINPAAERMLNVEREKLRGQCAKELLS
HHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
KFFTDEEFDQILKGETNVKEEKNLTTNEDMVVRAQLVPFKSEEKQYEGVIIALNDITEQE
HHCCCHHHHHHHCCCCCCCHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCHHH
KLIQMRQEFVANVSHELRTPLTSVKSYVETLLDGAHKDDEIAPRFLKVVQQETDRMVTMV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KDLLVLSQLDRKEPIIECRDINFMDVLDRSISAIESLTKDQKIELHLDYKSLEGEYIDVF
HHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCEEECC
NEKPEFIRISGDSDKLTQVFTNILENAIKYSPSGEWIQITVEDYYENIKISVKDNGMGIP
CCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCEEEEEECCCCCCC
AEDLPRIFERFYRVEKARSRARGGSGLGLAISREIIRNHGGDINVSSQEGRGTEVIVYLP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCEEEEEEC
KNQEVQYELGAN
CCCCEEEECCCC
>Mature Secondary Structure
MFKTVQWKLVVIYLLLVLLAMELISVYLLQSLDQYYLDDYSERMSTEAELAKSLLQRHMT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
EEQDADQISQLLGEFGQQAHNEITILDENGRVLATSSGEEELQGNIIVEEEITRALAGSQ
CCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHCCCEEEHHHHHHHHCCCC
GSNIRINPNTNIRQKSLAIPIESGNQVIGAVYLVGSLERVDNTLSEIRTILFTGTLFAML
CCEEEECCCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTALLGIILSKTITKPVKVVTRTAQAMAQGDFNQRIDVKSDDEIGNLGRMFNHLASRLDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TLKEISSEKGKIEAILTQMSDGVIAVNSNKEIIHINPAAERMLNVEREKLRGQCAKELLS
HHHHHHCCCCHHHHHHHHHCCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
KFFTDEEFDQILKGETNVKEEKNLTTNEDMVVRAQLVPFKSEEKQYEGVIIALNDITEQE
HHCCCHHHHHHHCCCCCCCHHCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCHHH
KLIQMRQEFVANVSHELRTPLTSVKSYVETLLDGAHKDDEIAPRFLKVVQQETDRMVTMV
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KDLLVLSQLDRKEPIIECRDINFMDVLDRSISAIESLTKDQKIELHLDYKSLEGEYIDVF
HHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCEEECC
NEKPEFIRISGDSDKLTQVFTNILENAIKYSPSGEWIQITVEDYYENIKISVKDNGMGIP
CCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCEEEEEECCCCCCC
AEDLPRIFERFYRVEKARSRARGGSGLGLAISREIIRNHGGDINVSSQEGRGTEVIVYLP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEECCCCCCCCCEEEEEEC
KNQEVQYELGAN
CCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]