Click here to switch to the map view.

The map label for this gene is rho [H]

Identifier: 188587465

GI number: 188587465

Start: 3106112

End: 3107356

Strand: Reverse

Name: rho [H]

Synonym: Nther_2875

Alternate gene names: 188587465

Gene position: 3107356-3106112 (Counterclockwise)

Preceding gene: 188587466

Following gene: 188587464

Centisome position: 98.16

GC content: 36.87

Gene sequence:

>1245_bases
TTGGATATTAAAGATTTAGAACAAAAAACAGTATCTGAACTACATGAAATTGCCAAAAAATATGGCGTGAAAAACTATAC
TAGATTAAAAAAAAGTGATTTAATTTTTAAATTAATTGAAAGCTATACTGAAAAAGATGGTTATAATTTTTCTGAAGGTG
TTTTAGAAATTATGCCCGACGGATATGGTTTTTTAAGACCGGACGGCTATACTCCTGGTAGTAATGATATTTATATTTCG
GCATCTCAAATCAAGAGATTTGGATTAAAAACTGGCGATCTGGTTTCTGGTAAAGTGCGTCCACCCAAGGATAATGAAAA
ATATATGGCTTTGTTGCATGTAGAAGCTGTGAATTCACGTCCCCCTGAAGAATCAAAAACAAGAAAAGATTTTTCTATCC
TTACCCCGATTCACCCAGATGCCCCTTTTCGATTAGAAATTAGGCAAGATATGTTAGCACCTCGCATGATTGATTTATTC
TCACCAATAGGGCGCGGACAGCGAGGGATGATAGTTAGTCCTCCTAAAGCAGGTAAAACTGTGTTGCTTAAGCAGCTAGC
CAATTGTATAGCTGAAAACCATCCAGAAACTGAGATTATAATTTTATTAATTGACGAGCGTCCAGAAGAAGTTACTGATA
TAGAAAGGTCTGTTGATGCTCAAGTGGTCAGTTCTACCTTTGATAATTATCCTGAAAATCATGTCAAACTTGCTGAACTA
GTTATGAAACGGGCTGAGCGCATGGTGGAAAACCAAAAGGACGTTGTAGTCTTGTTGGATTCTATGACACGTCTGGCTCG
AGCTTATAACTTGGTAATTCCCCCCAGTGGCAGAACTTTATCTGGAGGTATTGACCCTTCAGCTCTACACAAACCAAAGA
AATTCTTTGGAGCTGCCAGAAATATAGAAGAGGGAGGCAGTTTAACAATACTTTCTACTGCCCTAGTTGATACTGGAAGT
CGTATGGATGACGTAATTTATGAGGAATTCAAAGGTACTGGTAATATGGAGCTTCACTTGAGTAGAAAACTGGCTAATAG
AAGAATATTTCCAGCTATTGATATTTCACGTTCTGGTACCAGAAGGGAAGAGCTGTTACAAGATAAAAAACATTTAGAGT
TAATTTGGACTCTCAGGCGAGCTATGATGGATGCTAGTCCAGAAGAATTCTTAGAAACTGTAGGAGAAAAATTAAAACGA
ACTTCAAACAATGATGAATTTTTAAAGAATCTTCATCATATGTAA

Upstream 100 bases:

>100_bases
ATTTAAAATTTTATGTTTTAATTGATTTTACCTTGTTAAAAGATGTTACAAGGTAATATTCGTAATTAGGTTGGGGTAGT
TTTTAAGGAGGTAATAAAAA

Downstream 100 bases:

>100_bases
AATGGGCTGTTGCTCTTAGAAGGGACTTGTGTTATGATAATGGTTGCGAATTTGAAAATAATATTCTAACTTGAATTTAT
ATGAGCGAGGTGAAATATAA

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MDIKDLEQKTVSELHEIAKKYGVKNYTRLKKSDLIFKLIESYTEKDGYNFSEGVLEIMPDGYGFLRPDGYTPGSNDIYIS
ASQIKRFGLKTGDLVSGKVRPPKDNEKYMALLHVEAVNSRPPEESKTRKDFSILTPIHPDAPFRLEIRQDMLAPRMIDLF
SPIGRGQRGMIVSPPKAGKTVLLKQLANCIAENHPETEIIILLIDERPEEVTDIERSVDAQVVSSTFDNYPENHVKLAEL
VMKRAERMVENQKDVVVLLDSMTRLARAYNLVIPPSGRTLSGGIDPSALHKPKKFFGAARNIEEGGSLTILSTALVDTGS
RMDDVIYEEFKGTGNMELHLSRKLANRRIFPAIDISRSGTRREELLQDKKHLELIWTLRRAMMDASPEEFLETVGEKLKR
TSNNDEFLKNLHHM

Sequences:

>Translated_414_residues
MDIKDLEQKTVSELHEIAKKYGVKNYTRLKKSDLIFKLIESYTEKDGYNFSEGVLEIMPDGYGFLRPDGYTPGSNDIYIS
ASQIKRFGLKTGDLVSGKVRPPKDNEKYMALLHVEAVNSRPPEESKTRKDFSILTPIHPDAPFRLEIRQDMLAPRMIDLF
SPIGRGQRGMIVSPPKAGKTVLLKQLANCIAENHPETEIIILLIDERPEEVTDIERSVDAQVVSSTFDNYPENHVKLAEL
VMKRAERMVENQKDVVVLLDSMTRLARAYNLVIPPSGRTLSGGIDPSALHKPKKFFGAARNIEEGGSLTILSTALVDTGS
RMDDVIYEEFKGTGNMELHLSRKLANRRIFPAIDISRSGTRREELLQDKKHLELIWTLRRAMMDASPEEFLETVGEKLKR
TSNNDEFLKNLHHM
>Mature_414_residues
MDIKDLEQKTVSELHEIAKKYGVKNYTRLKKSDLIFKLIESYTEKDGYNFSEGVLEIMPDGYGFLRPDGYTPGSNDIYIS
ASQIKRFGLKTGDLVSGKVRPPKDNEKYMALLHVEAVNSRPPEESKTRKDFSILTPIHPDAPFRLEIRQDMLAPRMIDLF
SPIGRGQRGMIVSPPKAGKTVLLKQLANCIAENHPETEIIILLIDERPEEVTDIERSVDAQVVSSTFDNYPENHVKLAEL
VMKRAERMVENQKDVVVLLDSMTRLARAYNLVIPPSGRTLSGGIDPSALHKPKKFFGAARNIEEGGSLTILSTALVDTGS
RMDDVIYEEFKGTGNMELHLSRKLANRRIFPAIDISRSGTRREELLQDKKHLELIWTLRRAMMDASPEEFLETVGEKLKR
TSNNDEFLKNLHHM

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=414, Percent_Identity=53.1400966183575, Blast_Score=463, Evalue=1e-132,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 46936; Mature: 46936

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKDLEQKTVSELHEIAKKYGVKNYTRLKKSDLIFKLIESYTEKDGYNFSEGVLEIMPD
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHCCCC
GYGFLRPDGYTPGSNDIYISASQIKRFGLKTGDLVSGKVRPPKDNEKYMALLHVEAVNSR
CCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCC
PPEESKTRKDFSILTPIHPDAPFRLEIRQDMLAPRMIDLFSPIGRGQRGMIVSPPKAGKT
CCCHHHCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHH
VLLKQLANCIAENHPETEIIILLIDERPEEVTDIERSVDAQVVSSTFDNYPENHVKLAEL
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VMKRAERMVENQKDVVVLLDSMTRLARAYNLVIPPSGRTLSGGIDPSALHKPKKFFGAAR
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHEEEECCCCCEECCCCCHHHHCCCHHHHHHHC
NIEEGGSLTILSTALVDTGSRMDDVIYEEFKGTGNMELHLSRKLANRRIFPAIDISRSGT
CCCCCCCEEEEEHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCEECCCCCCC
RREELLQDKKHLELIWTLRRAMMDASPEEFLETVGEKLKRTSNNDEFLKNLHHM
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MDIKDLEQKTVSELHEIAKKYGVKNYTRLKKSDLIFKLIESYTEKDGYNFSEGVLEIMPD
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHCCCC
GYGFLRPDGYTPGSNDIYISASQIKRFGLKTGDLVSGKVRPPKDNEKYMALLHVEAVNSR
CCCCCCCCCCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCC
PPEESKTRKDFSILTPIHPDAPFRLEIRQDMLAPRMIDLFSPIGRGQRGMIVSPPKAGKT
CCCHHHCCCCCEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHH
VLLKQLANCIAENHPETEIIILLIDERPEEVTDIERSVDAQVVSSTFDNYPENHVKLAEL
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VMKRAERMVENQKDVVVLLDSMTRLARAYNLVIPPSGRTLSGGIDPSALHKPKKFFGAAR
HHHHHHHHHCCCCCEEEEHHHHHHHHHHHEEEECCCCCEECCCCCHHHHCCCHHHHHHHC
NIEEGGSLTILSTALVDTGSRMDDVIYEEFKGTGNMELHLSRKLANRRIFPAIDISRSGT
CCCCCCCEEEEEHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCEECCCCCCC
RREELLQDKKHLELIWTLRRAMMDASPEEFLETVGEKLKRTSNNDEFLKNLHHM
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]