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The map label for this gene is glpX [H]

Identifier: 188587466

GI number: 188587466

Start: 3107724

End: 3108695

Strand: Reverse

Name: glpX [H]

Synonym: Nther_2876

Alternate gene names: 188587466

Gene position: 3108695-3107724 (Counterclockwise)

Preceding gene: 188587467

Following gene: 188587465

Centisome position: 98.2

GC content: 42.08

Gene sequence:

>972_bases
ATGGAGAGAGAATTAGCTTTAGAACTAGTACGAGTAACCGAGGCTGCTGCTCTTGCTTCAGGAAGAATGATGGGTCGTGG
AGATAAAGAAGGTGCGGATCAAGCCGCAGTTGATGCGATGAGAAGGGCTTTTGATACCGTTCAAATAGATGGACGTGTGG
TGATTGGAGAGGGTGAAAAAGATGAGGCACCCATGCTATATATAGGAGAAGAAGTTGGAAGTAGAGATGGAATTCCCGTT
GATATAGCCGTTGATCCGGTAGAAGGCACTAACTTAGTGGCCAAGGGTCTTCCCAATGCCCTTTCTGTAGTAGCTGTAGC
ACCAAAAGATGGATTATTGTATGCCCCTGATATTTATATGGAAAAAATAGCTGTAGGTAAGGAAGCTAAAGGGTGTATTG
ATCTGGACGCTCCAGTAGAGGAAAATTTATCAGCTATTGCCAAGGCTAAGGGAAAGGATGTTTCTGATTTAGTAGCCATC
GTATTGGATAGACCAAGACATGAAGATATTATCCATGAAATTAAAAGGGCAGGAGCTAGAATCAAATTAATCAGCGATGG
TGACGTTTCAGCAGCCATAGCTACTGCTATACCTGATACTGGAGTAGATGTTTTATTCGGTGTTGGGGGTGCTCCTGAAG
GTGTAATTGCAGCTACTGCATTAAAATGTCTAGAAGGCGAAATGCAAGCACGCTTGAAGCCTAAAAATGGAGAACAAGAA
GATAGGCTTAAAGATATGGGGATCAATGACCCCTCTAGATTACTGCAAATGGAGGACCTAGTCAGTGGAGATGATGCTAT
GTTTGCAGTTACTGGAATTACAGATGGAGACTTATTAAGAGGCATCAGATATGAAGCTGGAAAGAAAGCACGCTCTCATA
GTTTGGTTATGAGAGCAAAAACTGGTACAGTTAGATTTATTGATGCCATTCACAGATTGGATAAAAAACCCTCTTACTAT
TATGAAGAGTAG

Upstream 100 bases:

>100_bases
GGAATAGAAAAATTCATGGAAGACTGGCATAAGAATAAACAAAAATAGATAAGCAGGTTAACTAGATTTTTCGAATGTTA
AATAAGGAGGAGGCTGGCTA

Downstream 100 bases:

>100_bases
TGTCAAAAACTTCCTGGTTGCTTTACTATGGCAACCAGGAAAATCTTAATGTTGTCTAGCATTTTGAGCTTGCACGCTTG
CCACGCTACAAGCAATGGTT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MERELALELVRVTEAAALASGRMMGRGDKEGADQAAVDAMRRAFDTVQIDGRVVIGEGEKDEAPMLYIGEEVGSRDGIPV
DIAVDPVEGTNLVAKGLPNALSVVAVAPKDGLLYAPDIYMEKIAVGKEAKGCIDLDAPVEENLSAIAKAKGKDVSDLVAI
VLDRPRHEDIIHEIKRAGARIKLISDGDVSAAIATAIPDTGVDVLFGVGGAPEGVIAATALKCLEGEMQARLKPKNGEQE
DRLKDMGINDPSRLLQMEDLVSGDDAMFAVTGITDGDLLRGIRYEAGKKARSHSLVMRAKTGTVRFIDAIHRLDKKPSYY
YEE

Sequences:

>Translated_323_residues
MERELALELVRVTEAAALASGRMMGRGDKEGADQAAVDAMRRAFDTVQIDGRVVIGEGEKDEAPMLYIGEEVGSRDGIPV
DIAVDPVEGTNLVAKGLPNALSVVAVAPKDGLLYAPDIYMEKIAVGKEAKGCIDLDAPVEENLSAIAKAKGKDVSDLVAI
VLDRPRHEDIIHEIKRAGARIKLISDGDVSAAIATAIPDTGVDVLFGVGGAPEGVIAATALKCLEGEMQARLKPKNGEQE
DRLKDMGINDPSRLLQMEDLVSGDDAMFAVTGITDGDLLRGIRYEAGKKARSHSLVMRAKTGTVRFIDAIHRLDKKPSYY
YEE
>Mature_323_residues
MERELALELVRVTEAAALASGRMMGRGDKEGADQAAVDAMRRAFDTVQIDGRVVIGEGEKDEAPMLYIGEEVGSRDGIPV
DIAVDPVEGTNLVAKGLPNALSVVAVAPKDGLLYAPDIYMEKIAVGKEAKGCIDLDAPVEENLSAIAKAKGKDVSDLVAI
VLDRPRHEDIIHEIKRAGARIKLISDGDVSAAIATAIPDTGVDVLFGVGGAPEGVIAATALKCLEGEMQARLKPKNGEQE
DRLKDMGINDPSRLLQMEDLVSGDDAMFAVTGITDGDLLRGIRYEAGKKARSHSLVMRAKTGTVRFIDAIHRLDKKPSYY
YEE

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=329, Percent_Identity=50.4559270516717, Blast_Score=305, Evalue=2e-84,
Organism=Escherichia coli, GI1789298, Length=321, Percent_Identity=46.7289719626168, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34547; Mature: 34547

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERELALELVRVTEAAALASGRMMGRGDKEGADQAAVDAMRRAFDTVQIDGRVVIGEGEK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCEEEECCCCC
DEAPMLYIGEEVGSRDGIPVDIAVDPVEGTNLVAKGLPNALSVVAVAPKDGLLYAPDIYM
CCCCEEEEEHHCCCCCCCEEEEEECCCCCCCHHHHCCCCCEEEEEECCCCCEEECCHHHH
EKIAVGKEAKGCIDLDAPVEENLSAIAKAKGKDVSDLVAIVLDRPRHEDIIHEIKRAGAR
HHHHCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCE
IKLISDGDVSAAIATAIPDTGVDVLFGVGGAPEGVIAATALKCLEGEMQARLKPKNGEQE
EEEEECCCCCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCHH
DRLKDMGINDPSRLLQMEDLVSGDDAMFAVTGITDGDLLRGIRYEAGKKARSHSLVMRAK
HHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEC
TGTVRFIDAIHRLDKKPSYYYEE
CCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MERELALELVRVTEAAALASGRMMGRGDKEGADQAAVDAMRRAFDTVQIDGRVVIGEGEK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCEEEECCCCC
DEAPMLYIGEEVGSRDGIPVDIAVDPVEGTNLVAKGLPNALSVVAVAPKDGLLYAPDIYM
CCCCEEEEEHHCCCCCCCEEEEEECCCCCCCHHHHCCCCCEEEEEECCCCCEEECCHHHH
EKIAVGKEAKGCIDLDAPVEENLSAIAKAKGKDVSDLVAIVLDRPRHEDIIHEIKRAGAR
HHHHCCCCCCCCEECCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCE
IKLISDGDVSAAIATAIPDTGVDVLFGVGGAPEGVIAATALKCLEGEMQARLKPKNGEQE
EEEEECCCCCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHEECCCCCCHH
DRLKDMGINDPSRLLQMEDLVSGDDAMFAVTGITDGDLLRGIRYEAGKKARSHSLVMRAK
HHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEEC
TGTVRFIDAIHRLDKKPSYYYEE
CCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]