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The map label for this gene is mntR [H]

Identifier: 188587393

GI number: 188587393

Start: 3027540

End: 3028058

Strand: Direct

Name: mntR [H]

Synonym: Nther_2802

Alternate gene names: 188587393

Gene position: 3027540-3028058 (Clockwise)

Preceding gene: 188587383

Following gene: 188587394

Centisome position: 95.64

GC content: 32.37

Gene sequence:

>519_bases
ATGAATAAGAATGAAAAAGACAATCGCAATGAAAAAGACAATCGCTTTGAAAATCAAGGAAAGGAATTTTACACCGATCG
AGGTTATGAACAAATTCAAAAATACGATTTAACACCTAGCATGGAAGATTATCTGGAGATGATTATTAGATTAAGTGATC
AACAGGGCTATACCAGGGTAAATAGAATTGCTGAAAGTTTAAATGTGAAACCTGCATCTGTATCTAAAATGATACAGAAA
TTATCTCAGAAATCATACTTAAAATATGAAAAATACGGTATGGTTCATTTGACAGCTAAAGGACAACAGATCGGAGAATA
CTTGCTTGAACGGCATCACATACTGGAAGAACTGTTAAAAACAATTGGGGCAAGGGGAGATTTACAAAGAGAAGTTGAAC
GAATTGAACACCACATCAGCTACGATAATTTTATGATTTTATCGGATTTTCTCGATTTTTTAAAAGATAACCCAGAAATA
CTCAGGCAATTTCATCAATATAAACAGAACAAAAAATAA

Upstream 100 bases:

>100_bases
TTCCAAAACTATCACCCTAATGTCGATATCAATAATAAGATAACACAGGTTAATTGATAATGACAATAGTTTTTAATACT
CATTTTGGGGAGGGGTTATT

Downstream 100 bases:

>100_bases
AATGTTTGAATTTCCCATGATTATGCCCTGATATTTTTTTGGACAAGCACAAGATATAAGCAGACCCATATATTATTAGT
GAAAGACTGGAGTTAACCGC

Product: iron (metal) dependent repressor, DtxR family

Products: NA

Alternate protein names: Manganese transport regulator [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNKNEKDNRNEKDNRFENQGKEFYTDRGYEQIQKYDLTPSMEDYLEMIIRLSDQQGYTRVNRIAESLNVKPASVSKMIQK
LSQKSYLKYEKYGMVHLTAKGQQIGEYLLERHHILEELLKTIGARGDLQREVERIEHHISYDNFMILSDFLDFLKDNPEI
LRQFHQYKQNKK

Sequences:

>Translated_172_residues
MNKNEKDNRNEKDNRFENQGKEFYTDRGYEQIQKYDLTPSMEDYLEMIIRLSDQQGYTRVNRIAESLNVKPASVSKMIQK
LSQKSYLKYEKYGMVHLTAKGQQIGEYLLERHHILEELLKTIGARGDLQREVERIEHHISYDNFMILSDFLDFLKDNPEI
LRQFHQYKQNKK
>Mature_172_residues
MNKNEKDNRNEKDNRFENQGKEFYTDRGYEQIQKYDLTPSMEDYLEMIIRLSDQQGYTRVNRIAESLNVKPASVSKMIQK
LSQKSYLKYEKYGMVHLTAKGQQIGEYLLERHHILEELLKTIGARGDLQREVERIEHHISYDNFMILSDFLDFLKDNPEI
LRQFHQYKQNKK

Specific function: Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787038, Length=118, Percent_Identity=28.8135593220339, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR022897
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress [H]

EC number: NA

Molecular weight: Translated: 20684; Mature: 20684

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNEKDNRNEKDNRFENQGKEFYTDRGYEQIQKYDLTPSMEDYLEMIIRLSDQQGYTRV
CCCCCCCCCCCHHHHHHHCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHH
NRIAESLNVKPASVSKMIQKLSQKSYLKYEKYGMVHLTAKGQQIGEYLLERHHILEELLK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHH
TIGARGDLQREVERIEHHISYDNFMILSDFLDFLKDNPEILRQFHQYKQNKK
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKNEKDNRNEKDNRFENQGKEFYTDRGYEQIQKYDLTPSMEDYLEMIIRLSDQQGYTRV
CCCCCCCCCCCHHHHHHHCCHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHH
NRIAESLNVKPASVSKMIQKLSQKSYLKYEKYGMVHLTAKGQQIGEYLLERHHILEELLK
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHH
TIGARGDLQREVERIEHHISYDNFMILSDFLDFLKDNPEILRQFHQYKQNKK
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]