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The map label for this gene is appC [H]

Identifier: 188587387

GI number: 188587387

Start: 3020799

End: 3021698

Strand: Reverse

Name: appC [H]

Synonym: Nther_2796

Alternate gene names: 188587387

Gene position: 3021698-3020799 (Counterclockwise)

Preceding gene: 188587388

Following gene: 188587386

Centisome position: 95.46

GC content: 41.22

Gene sequence:

>900_bases
TTGAGTAATACTGCAACTTCTACTGCCCAAGAGAGGGTGGAACCCAAAGGGGTTATCACTCCAAGGCAGCTGGTTTGGAA
GCAATTCAAAAAAAATAGATTAGCTCTCATTGGCATGTGTGTTTTGATATTTTTTGTCTTGCTTGCCATATTTGCTCCAG
TTTTGTCTACTCATGAAAGAGATGCCTACGATTTGACAAGGGCTGAAGAACCCCCCTCTAGTGAACATTATATGGGTACA
GACGAAATAGGAAGGGACATATATACAAGATTATTACATGGTGGTCGGGTTTCTTTATCAGTTGGAATAGTCGCTACAGG
TATTCAATTAGTTATCGGTATCATTTTAGGTTCTTTGGCTGGTTACAAAGGCGGGACTACCGATACTATAATCATGAGAT
TAACTGATATGTTTTTGGCTTTTCCTTTCCTTGCCATGGCCATTACTATAGCTGCAGTATTAGGCCCCAGTATCTATAAT
ACTATGATTGTTATCGGCATATTATCCTGGCCAAGGACTTGTCGAATTATCAGGGGAGAATTTTTGAAAATTAAAAATAC
TGATTATGTTAGAGCAGCCAAGGCTCTAGGACTTAGAGAGCTAAAACTGGTCGCCAGGCATATGATCCCTAATGCTTTAC
CACCTTTGATTGTTAATGCCACTTTATCCATGGCAACTGCAGTTTTGGTAGAAGCAGGCTTGTCCTTCTTAGGACTAGGG
GTAGTTCCACCTCAACCAAGTTGGGGTAATATGCTAGAGATAGCTAGAAACCTGCGGATCGTTGAGAATTTCTGGTGGAT
GTATGTACCTCCTGGCCTAATGATTTTCTTAACAGTGTTGAGTATTAATCTAGTAGGGGACGGCTTACGTGACGCCCTGG
ATCCTAGATTGAAGCAATAG

Upstream 100 bases:

>100_bases
TTTATGGTAATGCTGGGTAATTTACTGGCAGATGTGTTATATGCCGTTGTTGATCCCCGCATTAAATATAATTAATTTAT
TATAGAAGGGAGTGGATGGA

Downstream 100 bases:

>100_bases
GAGGGAGTGCTTTGGAAGAGCTGTTGAATGTTAAAAATTTGAAGACTAATTTTTATACAGATGATGGGATTGTCCGAGCA
GTCGACGATGTTAGTTTTAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSNTATSTAQERVEPKGVITPRQLVWKQFKKNRLALIGMCVLIFFVLLAIFAPVLSTHERDAYDLTRAEEPPSSEHYMGT
DEIGRDIYTRLLHGGRVSLSVGIVATGIQLVIGIILGSLAGYKGGTTDTIIMRLTDMFLAFPFLAMAITIAAVLGPSIYN
TMIVIGILSWPRTCRIIRGEFLKIKNTDYVRAAKALGLRELKLVARHMIPNALPPLIVNATLSMATAVLVEAGLSFLGLG
VVPPQPSWGNMLEIARNLRIVENFWWMYVPPGLMIFLTVLSINLVGDGLRDALDPRLKQ

Sequences:

>Translated_299_residues
MSNTATSTAQERVEPKGVITPRQLVWKQFKKNRLALIGMCVLIFFVLLAIFAPVLSTHERDAYDLTRAEEPPSSEHYMGT
DEIGRDIYTRLLHGGRVSLSVGIVATGIQLVIGIILGSLAGYKGGTTDTIIMRLTDMFLAFPFLAMAITIAAVLGPSIYN
TMIVIGILSWPRTCRIIRGEFLKIKNTDYVRAAKALGLRELKLVARHMIPNALPPLIVNATLSMATAVLVEAGLSFLGLG
VVPPQPSWGNMLEIARNLRIVENFWWMYVPPGLMIFLTVLSINLVGDGLRDALDPRLKQ
>Mature_298_residues
SNTATSTAQERVEPKGVITPRQLVWKQFKKNRLALIGMCVLIFFVLLAIFAPVLSTHERDAYDLTRAEEPPSSEHYMGTD
EIGRDIYTRLLHGGRVSLSVGIVATGIQLVIGIILGSLAGYKGGTTDTIIMRLTDMFLAFPFLAMAITIAAVLGPSIYNT
MIVIGILSWPRTCRIIRGEFLKIKNTDYVRAAKALGLRELKLVARHMIPNALPPLIVNATLSMATAVLVEAGLSFLGLGV
VPPQPSWGNMLEIARNLRIVENFWWMYVPPGLMIFLTVLSINLVGDGLRDALDPRLKQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=292, Percent_Identity=40.0684931506849, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1787054, Length=295, Percent_Identity=38.9830508474576, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1789964, Length=287, Percent_Identity=42.1602787456446, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1787498, Length=302, Percent_Identity=37.0860927152318, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=35.8024691358025, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1788505, Length=227, Percent_Identity=29.9559471365639, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787549, Length=274, Percent_Identity=31.7518248175182, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32913; Mature: 32781

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTATSTAQERVEPKGVITPRQLVWKQFKKNRLALIGMCVLIFFVLLAIFAPVLSTHER
CCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DAYDLTRAEEPPSSEHYMGTDEIGRDIYTRLLHGGRVSLSVGIVATGIQLVIGIILGSLA
CHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHC
GYKGGTTDTIIMRLTDMFLAFPFLAMAITIAAVLGPSIYNTMIVIGILSWPRTCRIIRGE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
FLKIKNTDYVRAAKALGLRELKLVARHMIPNALPPLIVNATLSMATAVLVEAGLSFLGLG
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VVPPQPSWGNMLEIARNLRIVENFWWMYVPPGLMIFLTVLSINLVGDGLRDALDPRLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure 
SNTATSTAQERVEPKGVITPRQLVWKQFKKNRLALIGMCVLIFFVLLAIFAPVLSTHER
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DAYDLTRAEEPPSSEHYMGTDEIGRDIYTRLLHGGRVSLSVGIVATGIQLVIGIILGSLA
CHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHC
GYKGGTTDTIIMRLTDMFLAFPFLAMAITIAAVLGPSIYNTMIVIGILSWPRTCRIIRGE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
FLKIKNTDYVRAAKALGLRELKLVARHMIPNALPPLIVNATLSMATAVLVEAGLSFLGLG
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
VVPPQPSWGNMLEIARNLRIVENFWWMYVPPGLMIFLTVLSINLVGDGLRDALDPRLKQ
CCCCCCCCCHHHHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]