| Definition | Natranaerobius thermophilus JW/NM-WN-LF, complete genome. |
|---|---|
| Accession | NC_010718 |
| Length | 3,165,557 |
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The map label for this gene is appD [H]
Identifier: 188587386
GI number: 188587386
Start: 3019807
End: 3020787
Strand: Reverse
Name: appD [H]
Synonym: Nther_2795
Alternate gene names: 188587386
Gene position: 3020787-3019807 (Counterclockwise)
Preceding gene: 188587387
Following gene: 188587385
Centisome position: 95.43
GC content: 36.19
Gene sequence:
>981_bases TTGGAAGAGCTGTTGAATGTTAAAAATTTGAAGACTAATTTTTATACAGATGATGGGATTGTCCGAGCAGTCGACGATGT TAGTTTTAGTGTAAATCGTGGTCAAATACTTGGTGTAGTAGGCGAATCCGGTTGTGGAAAGAGTGTAACTTCAATTAGTA TTATGAGATTAATTCAAGACCCTGGTAAAATTGATAATGGTGAAGTTGTTTTTAGAGATAGCAATCTTCTGGATTTTTCA GAGGGTCAAATGAGAAAAATTCGCGGAAATGATATATCTATGATATTCCAAGAACCTATGAGTGCACTGAATCCCGTATT TACTGTGAAAGATCAGTTAGGAGAAGCGATTAAGCTGCATCAGGGCTTGAGTGATAAGGAAGCTTTTGATAAAGGTCTCG AAATGTTGAAAAAAGTTGGTATTCCTAGAGCGGAAAATGTTATGCACGAATATCCTCATAGTTTGAGTGGGGGTATGTGC CAGAGAGTTATGATAGCCATGGCACTATCTTGTAATCCGGAATTATTAATAGCTGATGAACCAACTACAGCTTTGGATGT GACAATTCAAGCTCAAATTTTGGAATTAATCAAAGAACTAAAAAACGAATATAACTCATCAATAATGTTAATTACTCATG ACTTAGGAGTTATAGCTGAAATGGCTGACCACGTAATCGTCATGTATACTGGGAAAATTGTTGAGAATACGGATATAGTC ACATTATTTAAGAATCCGAGACATCCTTACACAATAGGTTTGATTAATTCTCGTCCGGATATCAAAGATGAATTAAGAGA ATTAAAGGCCATTCCAGGATCTGTTCCTAATTTGTTAGAGATGCCTGTAGGTTGTTCATTCCATCCTCGTTGTGAATATA AAACAGAAAAATGTGAACAAGAACCTCCTCCAATGGTTGATTTAACTGAAGACCATAAAGTAAGATGTTGGAATGTCGAC AAGACTGGAGGTGAGGATTAA
Upstream 100 bases:
>100_bases CTGGCCTAATGATTTTCTTAACAGTGTTGAGTATTAATCTAGTAGGGGACGGCTTACGTGACGCCCTGGATCCTAGATTG AAGCAATAGGAGGGAGTGCT
Downstream 100 bases:
>100_bases CTTGTCTGAAGAACCGATTTTAAAGGTGGAAAATCTTAAAAAATACTTTCCCATAAGGGCAGGAATACTTTCTAGAGTAG TTAATCATGTAAAGGCGGTA
Product: oligopeptide/dipeptide ABC transporter, ATPase subunit
Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 326; Mature: 326
Protein sequence:
>326_residues MEELLNVKNLKTNFYTDDGIVRAVDDVSFSVNRGQILGVVGESGCGKSVTSISIMRLIQDPGKIDNGEVVFRDSNLLDFS EGQMRKIRGNDISMIFQEPMSALNPVFTVKDQLGEAIKLHQGLSDKEAFDKGLEMLKKVGIPRAENVMHEYPHSLSGGMC QRVMIAMALSCNPELLIADEPTTALDVTIQAQILELIKELKNEYNSSIMLITHDLGVIAEMADHVIVMYTGKIVENTDIV TLFKNPRHPYTIGLINSRPDIKDELRELKAIPGSVPNLLEMPVGCSFHPRCEYKTEKCEQEPPPMVDLTEDHKVRCWNVD KTGGED
Sequences:
>Translated_326_residues MEELLNVKNLKTNFYTDDGIVRAVDDVSFSVNRGQILGVVGESGCGKSVTSISIMRLIQDPGKIDNGEVVFRDSNLLDFS EGQMRKIRGNDISMIFQEPMSALNPVFTVKDQLGEAIKLHQGLSDKEAFDKGLEMLKKVGIPRAENVMHEYPHSLSGGMC QRVMIAMALSCNPELLIADEPTTALDVTIQAQILELIKELKNEYNSSIMLITHDLGVIAEMADHVIVMYTGKIVENTDIV TLFKNPRHPYTIGLINSRPDIKDELRELKAIPGSVPNLLEMPVGCSFHPRCEYKTEKCEQEPPPMVDLTEDHKVRCWNVD KTGGED >Mature_326_residues MEELLNVKNLKTNFYTDDGIVRAVDDVSFSVNRGQILGVVGESGCGKSVTSISIMRLIQDPGKIDNGEVVFRDSNLLDFS EGQMRKIRGNDISMIFQEPMSALNPVFTVKDQLGEAIKLHQGLSDKEAFDKGLEMLKKVGIPRAENVMHEYPHSLSGGMC QRVMIAMALSCNPELLIADEPTTALDVTIQAQILELIKELKNEYNSSIMLITHDLGVIAEMADHVIVMYTGKIVENTDIV TLFKNPRHPYTIGLINSRPDIKDELRELKAIPGSVPNLLEMPVGCSFHPRCEYKTEKCEQEPPPMVDLTEDHKVRCWNVD KTGGED
Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI9665248, Length=221, Percent_Identity=28.5067873303167, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI255708477, Length=228, Percent_Identity=29.3859649122807, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI27436953, Length=211, Percent_Identity=26.0663507109005, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI27477115, Length=212, Percent_Identity=24.0566037735849, Blast_Score=67, Evalue=3e-11, Organism=Homo sapiens, GI21536376, Length=216, Percent_Identity=27.3148148148148, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI153792144, Length=212, Percent_Identity=24.0566037735849, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI48994883, Length=302, Percent_Identity=50, Blast_Score=313, Evalue=1e-86, Organism=Escherichia coli, GI1789963, Length=321, Percent_Identity=46.417445482866, Blast_Score=311, Evalue=4e-86, Organism=Escherichia coli, GI1787759, Length=317, Percent_Identity=42.5867507886435, Blast_Score=281, Evalue=5e-77, Organism=Escherichia coli, GI145693107, Length=264, Percent_Identity=51.5151515151515, Blast_Score=278, Evalue=3e-76, Organism=Escherichia coli, GI1788506, Length=260, Percent_Identity=47.6923076923077, Blast_Score=247, Evalue=7e-67, Organism=Escherichia coli, GI1787548, Length=305, Percent_Identity=39.0163934426229, Blast_Score=228, Evalue=4e-61, Organism=Escherichia coli, GI1789962, Length=313, Percent_Identity=38.3386581469649, Blast_Score=216, Evalue=1e-57, Organism=Escherichia coli, GI1787500, Length=330, Percent_Identity=37.2727272727273, Blast_Score=216, Evalue=1e-57, Organism=Escherichia coli, GI1787758, Length=327, Percent_Identity=33.6391437308869, Blast_Score=180, Evalue=9e-47, Organism=Escherichia coli, GI1789890, Length=234, Percent_Identity=38.4615384615385, Blast_Score=157, Evalue=1e-39, Organism=Escherichia coli, GI48994997, Length=256, Percent_Identity=32.8125, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI1789891, Length=239, Percent_Identity=33.4728033472803, Blast_Score=134, Evalue=1e-32, Organism=Escherichia coli, GI1787547, Length=260, Percent_Identity=31.1538461538462, Blast_Score=129, Evalue=3e-31, Organism=Escherichia coli, GI1789032, Length=233, Percent_Identity=33.0472103004292, Blast_Score=126, Evalue=2e-30, Organism=Escherichia coli, GI1786398, Length=272, Percent_Identity=33.8235294117647, Blast_Score=124, Evalue=7e-30, Organism=Escherichia coli, GI1788225, Length=248, Percent_Identity=32.258064516129, Blast_Score=117, Evalue=1e-27, Organism=Escherichia coli, GI1790162, Length=257, Percent_Identity=29.5719844357977, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI1787089, Length=240, Percent_Identity=34.5833333333333, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1788644, Length=255, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1787029, Length=243, Percent_Identity=29.6296296296296, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1788450, Length=232, Percent_Identity=28.448275862069, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1787712, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=5e-23, Organism=Escherichia coli, GI1786563, Length=220, Percent_Identity=31.8181818181818, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI87081834, Length=222, Percent_Identity=31.0810810810811, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI87081791, Length=254, Percent_Identity=29.1338582677165, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=27.5862068965517, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI87081709, Length=245, Percent_Identity=26.9387755102041, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1786703, Length=234, Percent_Identity=29.4871794871795, Blast_Score=92, Evalue=6e-20, Organism=Escherichia coli, GI1788761, Length=242, Percent_Identity=25.2066115702479, Blast_Score=91, Evalue=8e-20, Organism=Escherichia coli, GI1787105, Length=238, Percent_Identity=28.1512605042017, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1787164, Length=246, Percent_Identity=30.4878048780488, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1786872, Length=209, Percent_Identity=32.5358851674641, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1789586, Length=222, Percent_Identity=29.7297297297297, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1789672, Length=239, Percent_Identity=29.2887029288703, Blast_Score=88, Evalue=8e-19, Organism=Escherichia coli, GI1790467, Length=239, Percent_Identity=25.9414225941423, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787112, Length=223, Percent_Identity=32.2869955156951, Blast_Score=86, Evalue=5e-18, Organism=Escherichia coli, GI87082267, Length=240, Percent_Identity=24.5833333333333, Blast_Score=84, Evalue=2e-17, Organism=Escherichia coli, GI1786803, Length=222, Percent_Identity=26.5765765765766, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1786319, Length=244, Percent_Identity=29.0983606557377, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1789864, Length=256, Percent_Identity=25.390625, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1790739, Length=231, Percent_Identity=25.974025974026, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1788165, Length=259, Percent_Identity=28.1853281853282, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787792, Length=217, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789991, Length=241, Percent_Identity=28.2157676348548, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI48994943, Length=248, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789873, Length=213, Percent_Identity=28.6384976525822, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI87082268, Length=223, Percent_Identity=27.8026905829596, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1786345, Length=211, Percent_Identity=26.0663507109005, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1790534, Length=231, Percent_Identity=26.8398268398268, Blast_Score=71, Evalue=9e-14, Organism=Escherichia coli, GI1790190, Length=222, Percent_Identity=31.981981981982, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI48995001, Length=235, Percent_Identity=25.9574468085106, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI1789593, Length=232, Percent_Identity=26.2931034482759, Blast_Score=71, Evalue=1e-13, Organism=Escherichia coli, GI1787143, Length=225, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787182, Length=234, Percent_Identity=25.2136752136752, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1788053, Length=195, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=3e-11, Organism=Escherichia coli, GI1786253, Length=209, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1786698, Length=212, Percent_Identity=25.4716981132075, Blast_Score=62, Evalue=6e-11, Organism=Caenorhabditis elegans, GI115534520, Length=231, Percent_Identity=29.8701298701299, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI25146777, Length=213, Percent_Identity=30.5164319248826, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI32566680, Length=228, Percent_Identity=30.2631578947368, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI193208177, Length=218, Percent_Identity=29.8165137614679, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI212646699, Length=222, Percent_Identity=28.3783783783784, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17569143, Length=214, Percent_Identity=30.3738317757009, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17558664, Length=226, Percent_Identity=28.3185840707965, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI71996809, Length=236, Percent_Identity=27.9661016949153, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193211015, Length=236, Percent_Identity=27.9661016949153, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193211017, Length=236, Percent_Identity=27.9661016949153, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17541710, Length=252, Percent_Identity=30.1587301587302, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71992290, Length=233, Percent_Identity=29.1845493562232, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71983523, Length=217, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71983510, Length=217, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71983516, Length=217, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193209708, Length=221, Percent_Identity=31.2217194570136, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115533608, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17569145, Length=229, Percent_Identity=28.82096069869, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324498, Length=185, Percent_Identity=28.1081081081081, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6320296, Length=246, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6322640, Length=262, Percent_Identity=28.2442748091603, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI85726357, Length=222, Percent_Identity=27.9279279279279, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI17136662, Length=210, Percent_Identity=30, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24641565, Length=222, Percent_Identity=30.6306306306306, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI85725262, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28574150, Length=210, Percent_Identity=25.2380952380952, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI28574744, Length=203, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=4e-11, Organism=Drosophila melanogaster, GI116007328, Length=210, Percent_Identity=25.2380952380952, Blast_Score=66, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 - InterPro: IPR010066 - InterPro: IPR013563 [H]
Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]
EC number: NA
Molecular weight: Translated: 36344; Mature: 36344
Theoretical pI: Translated: 4.73; Mature: 4.73
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 4.6 %Met (Translated Protein) 6.7 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 4.6 %Met (Mature Protein) 6.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEELLNVKNLKTNFYTDDGIVRAVDDVSFSVNRGQILGVVGESGCGKSVTSISIMRLIQD CCHHHCHHHCCCCEECCCCEEEEECCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHC PGKIDNGEVVFRDSNLLDFSEGQMRKIRGNDISMIFQEPMSALNPVFTVKDQLGEAIKLH CCCCCCCEEEEECCCCEECCCCCCEEECCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHH QGLSDKEAFDKGLEMLKKVGIPRAENVMHEYPHSLSGGMCQRVMIAMALSCNPELLIADE CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECC PTTALDVTIQAQILELIKELKNEYNSSIMLITHDLGVIAEMADHVIVMYTGKIVENTDIV CCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHCCEEEEEECCEECCCCEE TLFKNPRHPYTIGLINSRPDIKDELRELKAIPGSVPNLLEMPVGCSFHPRCEYKTEKCEQ EEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHHCC EPPPMVDLTEDHKVRCWNVDKTGGED CCCCEEECCCCCCEEEEECCCCCCCC >Mature Secondary Structure MEELLNVKNLKTNFYTDDGIVRAVDDVSFSVNRGQILGVVGESGCGKSVTSISIMRLIQD CCHHHCHHHCCCCEECCCCEEEEECCCEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHC PGKIDNGEVVFRDSNLLDFSEGQMRKIRGNDISMIFQEPMSALNPVFTVKDQLGEAIKLH CCCCCCCEEEEECCCCEECCCCCCEEECCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHH QGLSDKEAFDKGLEMLKKVGIPRAENVMHEYPHSLSGGMCQRVMIAMALSCNPELLIADE CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEECC PTTALDVTIQAQILELIKELKNEYNSSIMLITHDLGVIAEMADHVIVMYTGKIVENTDIV CCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEEECHHHHHHHHCCEEEEEECCEECCCCEE TLFKNPRHPYTIGLINSRPDIKDELRELKAIPGSVPNLLEMPVGCSFHPRCEYKTEKCEQ EEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCHHHHCC EPPPMVDLTEDHKVRCWNVDKTGGED CCCCEEECCCCCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; oligopeptides [Periplasm]; H2O [C]
Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 7997159; 9384377 [H]