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The map label for this gene is dhaD [H]

Identifier: 188587303

GI number: 188587303

Start: 2922002

End: 2923102

Strand: Reverse

Name: dhaD [H]

Synonym: Nther_2706

Alternate gene names: 188587303

Gene position: 2923102-2922002 (Counterclockwise)

Preceding gene: 188587304

Following gene: 188587300

Centisome position: 92.34

GC content: 42.51

Gene sequence:

>1101_bases
GTGGAAAAATTATTAATTGCTCCATCTAAATACGTTCAAGGTCCTGGGGTAACTAAAACCCTGGGTGAATACGCTGAAAA
TTACGGTCAAAAAGCCTTGATTATCGGCGGTAATACAGCTTTGAAAGCATCTCAAACTAATATAACTGACAGCCTAAAAG
AACATCATGTTGACAGTGAAGTGGTTACTTTTAGTGGAAAGTGTACGGAAAAGGAAATAGATGATCTTCAAGACAAATTT
GCAGAGGTTGGAGCGGATTTTATTATTGGAGTGGGTGGAGGAAAAGTAATTGACACTGCTAAAGCAGTGGCCCACTACAA
GGATGTCCCCATGATCATCGTTCCCACCATTGCAGCTACTGATGCCCCTTGTAGTGCATTATCAGTCGTTTATACCGAGG
AAGGGGCTGTGGATGAGTATCTATTTTTAAAACAAAATCCCGATGTTGTTATGGTAGATACGGATATAATCAAACAAGCA
CCAGTGAGACTCTTTGTAGCCGGAATTGGCGATGCCCTGGCAACCTATTTCGAAGCCCGGGCCTGCTATCAGAACAACGC
TGATAGTGTAGCTGGTAAAAAAGCGACCAGAACAGCTCTGGCCCTGTCAGAACTTTGTTATGAAATTTTAGAAGAACACG
GAGAAAACTCTGTGACAGCTTTGAATAATAATGCCCTTACCCCGGCAGTAGAACAAGTGACAGAAGCCAATATCTTATTG
AGTGGCTTAGGTTTTGAAAGTACCGGGGTGGCAGCAGCACATGGGATTCATGATGGATTGACAGTTCTAGAAGAAACTAA
AGAAGCCTATCACGGAGAAAAGGTGGCCATTGGCACTCTGGCTCAGTTAGTTTTAGAAGGGGCTACTGAAGAATTAGATC
AAGTTCTAAAATTGTGTTATTCTGTTGGCCTTCCCACTACACTCAAGGAAATTGGTATAGAGACGGTAGATGAACAGCGA
TTGTTGAAAGTAGGTGAGGCTAGCTGTGCGGAAGGTAGCATGATTCACAACATGCCCTTTGAAGTCACTCCCGAAATGGT
TAAAGATGCCTTACTAACAGTGAATGGCCTGGGAGAAGAGGTAGATATATATATTGATTAA

Upstream 100 bases:

>100_bases
TAGAGAGAAAAAGAAAGTGTAACTTTGATATAATTAACGTGTTTTGTTATTATATTCACAAGGGTATTAGTAAAATTTAT
AAACTAGGGAGGTGAAGACT

Downstream 100 bases:

>100_bases
TTAGTATAATTAATCAGGCAAAAAGACAGGGCAGGAATAGTTAACCGACTATTCCTGCCCTGTCTTTGTTTAATAAGTTT
TTAGTCTTTACCTTTGATCA

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MEKLLIAPSKYVQGPGVTKTLGEYAENYGQKALIIGGNTALKASQTNITDSLKEHHVDSEVVTFSGKCTEKEIDDLQDKF
AEVGADFIIGVGGGKVIDTAKAVAHYKDVPMIIVPTIAATDAPCSALSVVYTEEGAVDEYLFLKQNPDVVMVDTDIIKQA
PVRLFVAGIGDALATYFEARACYQNNADSVAGKKATRTALALSELCYEILEEHGENSVTALNNNALTPAVEQVTEANILL
SGLGFESTGVAAAHGIHDGLTVLEETKEAYHGEKVAIGTLAQLVLEGATEELDQVLKLCYSVGLPTTLKEIGIETVDEQR
LLKVGEASCAEGSMIHNMPFEVTPEMVKDALLTVNGLGEEVDIYID

Sequences:

>Translated_366_residues
MEKLLIAPSKYVQGPGVTKTLGEYAENYGQKALIIGGNTALKASQTNITDSLKEHHVDSEVVTFSGKCTEKEIDDLQDKF
AEVGADFIIGVGGGKVIDTAKAVAHYKDVPMIIVPTIAATDAPCSALSVVYTEEGAVDEYLFLKQNPDVVMVDTDIIKQA
PVRLFVAGIGDALATYFEARACYQNNADSVAGKKATRTALALSELCYEILEEHGENSVTALNNNALTPAVEQVTEANILL
SGLGFESTGVAAAHGIHDGLTVLEETKEAYHGEKVAIGTLAQLVLEGATEELDQVLKLCYSVGLPTTLKEIGIETVDEQR
LLKVGEASCAEGSMIHNMPFEVTPEMVKDALLTVNGLGEEVDIYID
>Mature_366_residues
MEKLLIAPSKYVQGPGVTKTLGEYAENYGQKALIIGGNTALKASQTNITDSLKEHHVDSEVVTFSGKCTEKEIDDLQDKF
AEVGADFIIGVGGGKVIDTAKAVAHYKDVPMIIVPTIAATDAPCSALSVVYTEEGAVDEYLFLKQNPDVVMVDTDIIKQA
PVRLFVAGIGDALATYFEARACYQNNADSVAGKKATRTALALSELCYEILEEHGENSVTALNNNALTPAVEQVTEANILL
SGLGFESTGVAAAHGIHDGLTVLEETKEAYHGEKVAIGTLAQLVLEGATEELDQVLKLCYSVGLPTTLKEIGIETVDEQR
LLKVGEASCAEGSMIHNMPFEVTPEMVKDALLTVNGLGEEVDIYID

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Exhibits a rather broad substrate specificity since it can also oxidize 1,2-prop

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=363, Percent_Identity=49.5867768595041, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1786815, Length=362, Percent_Identity=31.4917127071823, Blast_Score=154, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 39023; Mature: 39023

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLLIAPSKYVQGPGVTKTLGEYAENYGQKALIIGGNTALKASQTNITDSLKEHHVDSE
CCCEEECCHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCEEECCCCCHHHHHHHHCCCCC
VVTFSGKCTEKEIDDLQDKFAEVGADFIIGVGGGKVIDTAKAVAHYKDVPMIIVPTIAAT
EEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCC
DAPCSALSVVYTEEGAVDEYLFLKQNPDVVMVDTDIIKQAPVRLFVAGIGDALATYFEAR
CCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEHHHHHHCCCEEEEEHHHHHHHHHHHHH
ACYQNNADSVAGKKATRTALALSELCYEILEEHGENSVTALNNNALTPAVEQVTEANILL
HHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHEE
SGLGFESTGVAAAHGIHDGLTVLEETKEAYHGEKVAIGTLAQLVLEGATEELDQVLKLCY
EECCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCHHHHHHHHHHHH
SVGLPTTLKEIGIETVDEQRLLKVGEASCAEGSMIHNMPFEVTPEMVKDALLTVNGLGEE
HCCCCHHHHHCCCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCE
VDIYID
EEEEEC
>Mature Secondary Structure
MEKLLIAPSKYVQGPGVTKTLGEYAENYGQKALIIGGNTALKASQTNITDSLKEHHVDSE
CCCEEECCHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCEEECCCCCHHHHHHHHCCCCC
VVTFSGKCTEKEIDDLQDKFAEVGADFIIGVGGGKVIDTAKAVAHYKDVPMIIVPTIAAT
EEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCC
DAPCSALSVVYTEEGAVDEYLFLKQNPDVVMVDTDIIKQAPVRLFVAGIGDALATYFEAR
CCCCCCEEEEEECCCCCCCEEEEECCCCEEEEEHHHHHHCCCEEEEEHHHHHHHHHHHHH
ACYQNNADSVAGKKATRTALALSELCYEILEEHGENSVTALNNNALTPAVEQVTEANILL
HHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHEE
SGLGFESTGVAAAHGIHDGLTVLEETKEAYHGEKVAIGTLAQLVLEGATEELDQVLKLCY
EECCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCHHHHHHHHHHHH
SVGLPTTLKEIGIETVDEQRLLKVGEASCAEGSMIHNMPFEVTPEMVKDALLTVNGLGEE
HCCCCHHHHHCCCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCE
VDIYID
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA