BacMap

Definition	Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession	NC_010718
Length	3,165,557

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The map label for this gene is dnaJ [H]

Identifier: 188587213

GI number: 188587213

Start: 2808103

End: 2808981

Strand: Reverse

Name: dnaJ [H]

Synonym: Nther_2614

Alternate gene names: 188587213

Gene position: 2808981-2808103 (Counterclockwise)

Preceding gene: 188587214

Following gene: 188587211

Centisome position: 88.74

GC content: 41.52

Gene sequence:

>879_bases
TTGGCGAACTATTATGAAATTTTAGGAGTTAGTCGAGACGCAGATAAAGACCAGATTGAAAAGGCTTATAGGCAGCTTGC
CAAGGAATACCATCCTGACAAGCACAAGGACAACCCCCTGGCTCACTTAGCAGAAGATAAGATGAAACAGTTCAATCAAG
CTTATGAAGTATTGAGCGATCCAAATAAACGGCAAAAATACGATGAGAGGATAAAAAATCAGCAAGGACAAGGATCCTCA
GGGACCGGAAAACAGCAGGCTTCAGGTAGTAGCAACTTTAGCGACGGGAATGCAGGAAGCAATTCAGGAGCTAAAGGAAG
TCAACAAAGTCAAGGAAGTCAAAGAGGGCAAAAGGGTAATTTTGTCGCTTGCAATGAACACCCTGACAGACCTGCCGTGT
CTGGTTGCGGCTTCTGTAATATCCCCCTTTGCCAGGAATGTTATCATAGGTTTAATATAGTTTCTTGCCCTGACTGTTTG
CTTGAATATAATCGAGGTTATTTAAATGAACTGAAAAAACCCTTGATTTCAACAGGGATAGCAGCAGTTATTGGATTTAT
TTTGGGATTATCTTCAAATTTTGGGATGGCGATATTAGGCATGTTATATGCTATTGGACTTTATTGGGGATGGCACTGGG
TTAAAGAAGGGATTTTTTATGGAGCTCTTAGTGGATTTGCATTTGGCCCCATAGGGATATTTACTTCTTTGGTTATGTTA
CTTATGTTTGGCTGGATCCCTGGTGTGATCAGAGCTTTGACCCACATAATACCGGCAGCTTACAAGTTATATACAGAGGC
TCCAAAAGTCAAAGAAGCCGAGGAATATATTATGAGCATTAAAAACGAAAGCACCAACACAGGCCAAGCTGCGGACTAA

Upstream 100 bases:

>100_bases
TTTTTACTTTTTACAATTTATATACGATATAAAGGAGCAGAAAGTCCACTGCTTTAGCTGTGGGAGTATGTCAAAAATAA
TTTTACAAGGAGGTGTTAGT

Downstream 100 bases:

>100_bases
ATTCATATTTTTGATAGTTTCGATTGAGGATTTTTAGTTGAATATAGTTGAATACATTAAGTGTAAGGCATTTTCTAAAG
CGACTGGCCCTGATTAAACG

Product: heat shock protein DnaJ domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MANYYEILGVSRDADKDQIEKAYRQLAKEYHPDKHKDNPLAHLAEDKMKQFNQAYEVLSDPNKRQKYDERIKNQQGQGSS
GTGKQQASGSSNFSDGNAGSNSGAKGSQQSQGSQRGQKGNFVACNEHPDRPAVSGCGFCNIPLCQECYHRFNIVSCPDCL
LEYNRGYLNELKKPLISTGIAAVIGFILGLSSNFGMAILGMLYAIGLYWGWHWVKEGIFYGALSGFAFGPIGIFTSLVML
LMFGWIPGVIRALTHIIPAAYKLYTEAPKVKEAEEYIMSIKNESTNTGQAAD

Sequences:

>Translated_292_residues
MANYYEILGVSRDADKDQIEKAYRQLAKEYHPDKHKDNPLAHLAEDKMKQFNQAYEVLSDPNKRQKYDERIKNQQGQGSS
GTGKQQASGSSNFSDGNAGSNSGAKGSQQSQGSQRGQKGNFVACNEHPDRPAVSGCGFCNIPLCQECYHRFNIVSCPDCL
LEYNRGYLNELKKPLISTGIAAVIGFILGLSSNFGMAILGMLYAIGLYWGWHWVKEGIFYGALSGFAFGPIGIFTSLVML
LMFGWIPGVIRALTHIIPAAYKLYTEAPKVKEAEEYIMSIKNESTNTGQAAD
>Mature_291_residues
ANYYEILGVSRDADKDQIEKAYRQLAKEYHPDKHKDNPLAHLAEDKMKQFNQAYEVLSDPNKRQKYDERIKNQQGQGSSG
TGKQQASGSSNFSDGNAGSNSGAKGSQQSQGSQRGQKGNFVACNEHPDRPAVSGCGFCNIPLCQECYHRFNIVSCPDCLL
EYNRGYLNELKKPLISTGIAAVIGFILGLSSNFGMAILGMLYAIGLYWGWHWVKEGIFYGALSGFAFGPIGIFTSLVMLL
MFGWIPGVIRALTHIIPAAYKLYTEAPKVKEAEEYIMSIKNESTNTGQAAD

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=108, Percent_Identity=42.5925925925926, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI88501736, Length=91, Percent_Identity=48.3516483516484, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI205360840, Length=108, Percent_Identity=42.5925925925926, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27151736, Length=91, Percent_Identity=48.3516483516484, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI23503241, Length=68, Percent_Identity=55.8823529411765, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4885495, Length=69, Percent_Identity=53.6231884057971, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI17388799, Length=69, Percent_Identity=53.6231884057971, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI201862587, Length=67, Percent_Identity=50.7462686567164, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI201862518, Length=67, Percent_Identity=50.7462686567164, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI56549115, Length=67, Percent_Identity=50.7462686567164, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI9558755, Length=125, Percent_Identity=38.4, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI22749377, Length=67, Percent_Identity=53.7313432835821, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI217035105, Length=66, Percent_Identity=48.4848484848485, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI56687498, Length=65, Percent_Identity=52.3076923076923, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI47777312, Length=68, Percent_Identity=51.4705882352941, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI194328760, Length=68, Percent_Identity=51.4705882352941, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI194328758, Length=68, Percent_Identity=51.4705882352941, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI72534740, Length=66, Percent_Identity=50, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI6631085, Length=67, Percent_Identity=49.2537313432836, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI5031741, Length=64, Percent_Identity=53.125, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI45504382, Length=65, Percent_Identity=47.6923076923077, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI5453690, Length=66, Percent_Identity=46.969696969697, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI7706495, Length=66, Percent_Identity=48.4848484848485, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786197, Length=67, Percent_Identity=49.2537313432836, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532378, Length=67, Percent_Identity=52.2388059701493, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI212645553, Length=66, Percent_Identity=50, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17534355, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17553098, Length=66, Percent_Identity=50, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17553096, Length=66, Percent_Identity=50, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507263, Length=66, Percent_Identity=48.4848484848485, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554644, Length=66, Percent_Identity=46.969696969697, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323119, Length=77, Percent_Identity=45.4545454545455, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=151, Percent_Identity=36.4238410596026, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320888, Length=68, Percent_Identity=48.5294117647059, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=67, Percent_Identity=46.2686567164179, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322388, Length=68, Percent_Identity=50, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI85726398, Length=80, Percent_Identity=51.25, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654066, Length=96, Percent_Identity=41.6666666666667, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654070, Length=96, Percent_Identity=41.6666666666667, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654068, Length=96, Percent_Identity=41.6666666666667, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654072, Length=96, Percent_Identity=41.6666666666667, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920464, Length=66, Percent_Identity=50, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI18858081, Length=96, Percent_Identity=43.75, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161077138, Length=70, Percent_Identity=48.5714285714286, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129487, Length=66, Percent_Identity=53.030303030303, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584014, Length=66, Percent_Identity=53.030303030303, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658562, Length=66, Percent_Identity=50, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24658555, Length=66, Percent_Identity=50, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45549272, Length=83, Percent_Identity=44.578313253012, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45552813, Length=83, Percent_Identity=44.578313253012, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19922238, Length=66, Percent_Identity=46.969696969697, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI45552811, Length=83, Percent_Identity=44.578313253012, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646562, Length=66, Percent_Identity=53.030303030303, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646560, Length=66, Percent_Identity=53.030303030303, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646558, Length=66, Percent_Identity=53.030303030303, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646556, Length=66, Percent_Identity=53.030303030303, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357547, Length=66, Percent_Identity=53.030303030303, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737735, Length=64, Percent_Identity=51.5625, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574723, Length=64, Percent_Identity=51.5625, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668523, Length=64, Percent_Identity=51.5625, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 32190; Mature: 32059

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYYEILGVSRDADKDQIEKAYRQLAKEYHPDKHKDNPLAHLAEDKMKQFNQAYEVLSD
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PNKRQKYDERIKNQQGQGSSGTGKQQASGSSNFSDGNAGSNSGAKGSQQSQGSQRGQKGN
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
FVACNEHPDRPAVSGCGFCNIPLCQECYHRFNIVSCPDCLLEYNRGYLNELKKPLISTGI
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
AAVIGFILGLSSNFGMAILGMLYAIGLYWGWHWVKEGIFYGALSGFAFGPIGIFTSLVML
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LMFGWIPGVIRALTHIIPAAYKLYTEAPKVKEAEEYIMSIKNESTNTGQAAD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ANYYEILGVSRDADKDQIEKAYRQLAKEYHPDKHKDNPLAHLAEDKMKQFNQAYEVLSD
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PNKRQKYDERIKNQQGQGSSGTGKQQASGSSNFSDGNAGSNSGAKGSQQSQGSQRGQKGN
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCC
FVACNEHPDRPAVSGCGFCNIPLCQECYHRFNIVSCPDCLLEYNRGYLNELKKPLISTGI
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHH
AAVIGFILGLSSNFGMAILGMLYAIGLYWGWHWVKEGIFYGALSGFAFGPIGIFTSLVML
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LMFGWIPGVIRALTHIIPAAYKLYTEAPKVKEAEEYIMSIKNESTNTGQAAD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA