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The map label for this gene is yeeO [C]

Identifier: 188587211

GI number: 188587211

Start: 2805703

End: 2807082

Strand: Reverse

Name: yeeO [C]

Synonym: Nther_2612

Alternate gene names: 188587211

Gene position: 2807082-2805703 (Counterclockwise)

Preceding gene: 188587213

Following gene: 188587210

Centisome position: 88.68

GC content: 36.67

Gene sequence:

>1380_bases
TTGAAAGTATCAAGTAGCGATAGACTAGGTACTGATCCTATATTACCCCTATTATTAAAGCTTTCTCTTCCCGGAATAGT
AGCTATGGGAATACAAGCTCTCTACAACGTAATAGATAGTTTTTTTGTAGCACAGGTAAATGAAGAAGCCATCGCCGGAC
TTTCGGTGGCTTTTCCCATGCAGCTTTTTTTAATTGCACTTTCTGTGGGGACAGGAGTCGGTACCAGTTCTCTGATTTCT
AGAATGTTAGGCAAAGGGGACAGAAACGGAGCTATAAGTGTGGTAGAGCATGTCTTAGTTATATCTGCAATTTATAGTGT
TGTTGTTTTTTTAATTGGTTTCCTATTGCCAGAAAGTTTTATTTATATTTTCACCGATGATCATCTGATTGCCCAATATG
CTTTCGAGTATGGACGTGTAATTTTAATGGGGGCATCACCGTTGTTTTTTGGATTTTTAATAAGTGATGCATTGAGGGGC
CAGGGCAATACTTTGATTCCCATGATAGGTATGGTCTCAGGTGCCATTACTAATATTTTGCTAGACCCTATTTTGATCTA
TGGAATGGGACCTATTCCTCGCCTTGAAGTGCAAGGAGCTGCCATAGCAACTGTCATAAGCAAGACGGTCACTTTTGCTG
TAGTTTTCTATGAACTGTTGATAGGAGAAAATGAAGTAAAACCAAAATTCCGAGATGGTTTAAAAAACTTTAAATTCAAT
AAAGAGATAATTAAAAATATATATGCAGTAGGACTGCCTGCAGCAGTAATGCAAATGTTGGCTTCCATAATGATAAGCGG
ATTAAACATTATTGTAGGAAATTTGAATGCTTTAGCTTTGTCTGCAACCGGTATATATTTCCGAATTCAATCTTTTGTTT
TTATGCCGGTTTTCGGTCTAAATCAAGGTTATATTCCCTTGGTAGGCTATAATTTCAGTAATGGCAATGCAGAGAGGGTC
AAAAAAGTCATTGGTTATGGAGCGTTAATTGCATGTGGATTTACTAGTCTAGGATTTATCGGGTTCCAGTTTATACCTGA
AATAATTGCTGGCCCTTTTGTAGAAAGCCAGGAATTAATGGATATTGTGGTAACTGCATTTAAAACAATAAGTATTGCCT
TTCCCATAATCGGACCAGCCATAATAGGTGCAACCACCTTTCAAGCTATTGGCAAAGGCATACCCTCATTAACACTATCT
TTTTTTCGACAAATCATTTTACTTTTACCTATAGCTTATTTCTTATCATTAACTGGTAATTTAGATTTAGTCTGGTTTGC
TTTTCCAATATCAGAATTTGTATCCTTTATCTTTATGATCATCTGGCTTTATATCACTTTGAAGAAAGAGTTGATATTTG
CTAAATTTCAGCGGGGGTGA

Upstream 100 bases:

>100_bases
AATTGTGATTCAAACCTGAATGTATAGATATTTAAATATGAAAATGATAAGATTTTTAAAGAGTAGGTAGAGCAGTATAT
CGAAATGGAGGTCGAAAATC

Downstream 100 bases:

>100_bases
TTTTATTCTAAATAAGTCTTATATATTATTACTGTCCTTCTTTTTGATTGTATTCATGTCCTTTATGCTTTTTAGTATTG
GTTGCAGTGAAGAAAATAAA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKVSSSDRLGTDPILPLLLKLSLPGIVAMGIQALYNVIDSFFVAQVNEEAIAGLSVAFPMQLFLIALSVGTGVGTSSLIS
RMLGKGDRNGAISVVEHVLVISAIYSVVVFLIGFLLPESFIYIFTDDHLIAQYAFEYGRVILMGASPLFFGFLISDALRG
QGNTLIPMIGMVSGAITNILLDPILIYGMGPIPRLEVQGAAIATVISKTVTFAVVFYELLIGENEVKPKFRDGLKNFKFN
KEIIKNIYAVGLPAAVMQMLASIMISGLNIIVGNLNALALSATGIYFRIQSFVFMPVFGLNQGYIPLVGYNFSNGNAERV
KKVIGYGALIACGFTSLGFIGFQFIPEIIAGPFVESQELMDIVVTAFKTISIAFPIIGPAIIGATTFQAIGKGIPSLTLS
FFRQIILLLPIAYFLSLTGNLDLVWFAFPISEFVSFIFMIIWLYITLKKELIFAKFQRG

Sequences:

>Translated_459_residues
MKVSSSDRLGTDPILPLLLKLSLPGIVAMGIQALYNVIDSFFVAQVNEEAIAGLSVAFPMQLFLIALSVGTGVGTSSLIS
RMLGKGDRNGAISVVEHVLVISAIYSVVVFLIGFLLPESFIYIFTDDHLIAQYAFEYGRVILMGASPLFFGFLISDALRG
QGNTLIPMIGMVSGAITNILLDPILIYGMGPIPRLEVQGAAIATVISKTVTFAVVFYELLIGENEVKPKFRDGLKNFKFN
KEIIKNIYAVGLPAAVMQMLASIMISGLNIIVGNLNALALSATGIYFRIQSFVFMPVFGLNQGYIPLVGYNFSNGNAERV
KKVIGYGALIACGFTSLGFIGFQFIPEIIAGPFVESQELMDIVVTAFKTISIAFPIIGPAIIGATTFQAIGKGIPSLTLS
FFRQIILLLPIAYFLSLTGNLDLVWFAFPISEFVSFIFMIIWLYITLKKELIFAKFQRG
>Mature_459_residues
MKVSSSDRLGTDPILPLLLKLSLPGIVAMGIQALYNVIDSFFVAQVNEEAIAGLSVAFPMQLFLIALSVGTGVGTSSLIS
RMLGKGDRNGAISVVEHVLVISAIYSVVVFLIGFLLPESFIYIFTDDHLIAQYAFEYGRVILMGASPLFFGFLISDALRG
QGNTLIPMIGMVSGAITNILLDPILIYGMGPIPRLEVQGAAIATVISKTVTFAVVFYELLIGENEVKPKFRDGLKNFKFN
KEIIKNIYAVGLPAAVMQMLASIMISGLNIIVGNLNALALSATGIYFRIQSFVFMPVFGLNQGYIPLVGYNFSNGNAERV
KKVIGYGALIACGFTSLGFIGFQFIPEIIAGPFVESQELMDIVVTAFKTISIAFPIIGPAIIGATTFQAIGKGIPSLTLS
FFRQIILLLPIAYFLSLTGNLDLVWFAFPISEFVSFIFMIIWLYITLKKELIFAKFQRG

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=262, Percent_Identity=27.8625954198473, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49850; Mature: 49850

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSSSDRLGTDPILPLLLKLSLPGIVAMGIQALYNVIDSFFVAQVNEEAIAGLSVAFPM
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHH
QLFLIALSVGTGVGTSSLISRMLGKGDRNGAISVVEHVLVISAIYSVVVFLIGFLLPESF
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IYIFTDDHLIAQYAFEYGRVILMGASPLFFGFLISDALRGQGNTLIPMIGMVSGAITNIL
EEEEECCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LDPILIYGMGPIPRLEVQGAAIATVISKTVTFAVVFYELLIGENEVKPKFRDGLKNFKFN
HHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
KEIIKNIYAVGLPAAVMQMLASIMISGLNIIVGNLNALALSATGIYFRIQSFVFMPVFGL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHEEECCCEEEEEHHHHHHHHHHHHHHHHHCC
NQGYIPLVGYNFSNGNAERVKKVIGYGALIACGFTSLGFIGFQFIPEIIAGPFVESQELM
CCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DIVVTAFKTISIAFPIIGPAIIGATTFQAIGKGIPSLTLSFFRQIILLLPIAYFLSLTGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LDLVWFAFPISEFVSFIFMIIWLYITLKKELIFAKFQRG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVSSSDRLGTDPILPLLLKLSLPGIVAMGIQALYNVIDSFFVAQVNEEAIAGLSVAFPM
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHH
QLFLIALSVGTGVGTSSLISRMLGKGDRNGAISVVEHVLVISAIYSVVVFLIGFLLPESF
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IYIFTDDHLIAQYAFEYGRVILMGASPLFFGFLISDALRGQGNTLIPMIGMVSGAITNIL
EEEEECCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LDPILIYGMGPIPRLEVQGAAIATVISKTVTFAVVFYELLIGENEVKPKFRDGLKNFKFN
HHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
KEIIKNIYAVGLPAAVMQMLASIMISGLNIIVGNLNALALSATGIYFRIQSFVFMPVFGL
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHEEECCCEEEEEHHHHHHHHHHHHHHHHHCC
NQGYIPLVGYNFSNGNAERVKKVIGYGALIACGFTSLGFIGFQFIPEIIAGPFVESQELM
CCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
DIVVTAFKTISIAFPIIGPAIIGATTFQAIGKGIPSLTLSFFRQIILLLPIAYFLSLTGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LDLVWFAFPISEFVSFIFMIIWLYITLKKELIFAKFQRG
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]