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The map label for this gene is ifcA [H]

Identifier: 188587074

GI number: 188587074

Start: 2652294

End: 2654093

Strand: Reverse

Name: ifcA [H]

Synonym: Nther_2466

Alternate gene names: 188587074

Gene position: 2654093-2652294 (Counterclockwise)

Preceding gene: 188587075

Following gene: 188587072

Centisome position: 83.84

GC content: 37.56

Gene sequence:

>1800_bases
ATGTTTCAAAAGAGAAACTTATTATTAATTATGTTAACATTTGTTCTGCTGTTCACATTCTCCGTGGGATGCAATGGAGA
TAAGGAAGTAGGAGAGGAACCAGGAGAGGAAGAGTTGGCACTAGAAGAAGGTACATATGAGGGAAGTTCATATGGACACA
ATGCAGAAATTGAAGTAGAGGTTACAATTGAAGATGAAGATATCTCTGATATCGAAGTTTTATCTCATGAAGAATCTGAG
ATATTAACAGATCCAGTATTTGAAGAAATTATCCCAGCCATTGTGGAAAACAACAATACTAATGTAGACTCCATTTCAGG
CGCAACTGTCACAAGTTTAGCACTAGTTAGTGCAGTTGAAGATGCATTAAAAGAGGCAGGTGCTGAAGAATACTTTGAAG
GGGAAATGGTTGAAGTTGATAGTGCTTCTGAAATCGCTGATTCTACCTATGATGTAGTAGTAGTTGGTGGTGGAGGTGCT
GGTCTAGTATCAGCAATTGAAGCAAAGTCACAAGGTGCAGATGTTGTGTTATTAGAAAAGATGCCTTATTTAGGTGGTAA
CACCCTAGTATCTGGAGGAGAGTTTAATGCTCCAAACACTTGGGTTCAGGAAAACCCAGATATTGATGACAGTGTAGATC
AATTTGTTGAAGATACCCTTGAAGGCGGAGATTATGAAGCAGATGAAGATCTTGTGCAAACACTAGCAGAAAATGTAACT
GAAGATGCGGAGTGGATGAAAGACTATGTAGGTGTAGAATTTGTCGATGACTATCTTATGCATTTTGGAGGACATGAAGT
GCCCAGGGCACTTTATCCAATTGGTGGCTCCGGACTAGAACTGATTAGTAGTTTAGAGGAACGAGCTTTGGATGATGAGA
TTCCAATTAAATTTAATACTGAAGCAAAAGAATTACTTACGGATGAAGATGGTAGAGTTGTAGGTGTAAAAGTGGAAGAT
CATGAAGGAGAAATAGCAAATATTGAGGCAGAAGATGGGGTTATTATGGCAACCGGTGGATTTGGTGCAAATATTGATAT
GACTCAAAAGTATAATCCAGACATTGACGATAGATATAATACTACTAATGTTCCAGGAGCAACTGGTGAAGGAATTCTAA
TGGCAAAAGAAATAGGTGCTGACTTAGTAGATATGGAGTTTATTCAAACTTATCCCACTTGTAATACGCAAACGGGTCAC
TTGTCATATGTTGCAGATACTAGATTTGATGGTGCTATTTTAGTTAACCAGGAAGGCGAAAGATTTGTCGAAGAGTTAGA
TCGTCGTGATGTGATTTCTGAAGCTATTTTAGATCAAACTGGGTCTGTAGCTTATCTAATGTGGGACAACCATATAAAAG
AAAATAGTAATATGGATAATTACATGACAGAATTTGAAAACCTGAAGGAAACTGATCAGATAATTAAAGCTGACTCTATT
GAAGAGGCAGCAGAATTTTTTGAGATTGATGTTGATGAACTTAAAAATACGGTGGAACAATACAATGAATATGTAAAACA
AGGTGAAGATGAAGACTTCAATCGTCGTGGTGATCTATTAGAATTAAAAGAAGGACCTTACTATATCCAAGAAGTGGCAC
CTGCTATTCACCATACCATGGGTGGAATTAAGATAAACGAAGAAGCTCAAGTTATTGATACAGAGGGTGAAATAATTGAA
GGGCTTTATGCTGCAGGTGAAATCACTGGTGGAATTCATGGTAACAATCGCTTAGGTGGTAACGCTATAGCAGATTTAAT
AGTTTTTGGTAGAATTGCGGGAGATAACGTTTCTAAATAA

Upstream 100 bases:

>100_bases
TCAAAAAACCTGAAATTTGTGCAAATACAAAAATCGTTTCTTAGCTTATAATTTGGTTGTGTTAAGAAATGTATAACAAG
TTAAAAGGAGGGGGTTGTAT

Downstream 100 bases:

>100_bases
ATATTCAAGTTAAAAGACTGCACCCCGAAAGTGTGATAGGATACTTTTGGGGTGCAGTTTTTGTTGTTCTAAAAAGTAAC
AGTTTGATGGCAAATGCGAA

Product: flavocytochrome c

Products: NA

Alternate protein names: Fe(3+)-induced flavocytochrome C3; Ifc3; Iron(III)-induced flavocytochrome C3 [H]

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MFQKRNLLLIMLTFVLLFTFSVGCNGDKEVGEEPGEEELALEEGTYEGSSYGHNAEIEVEVTIEDEDISDIEVLSHEESE
ILTDPVFEEIIPAIVENNNTNVDSISGATVTSLALVSAVEDALKEAGAEEYFEGEMVEVDSASEIADSTYDVVVVGGGGA
GLVSAIEAKSQGADVVLLEKMPYLGGNTLVSGGEFNAPNTWVQENPDIDDSVDQFVEDTLEGGDYEADEDLVQTLAENVT
EDAEWMKDYVGVEFVDDYLMHFGGHEVPRALYPIGGSGLELISSLEERALDDEIPIKFNTEAKELLTDEDGRVVGVKVED
HEGEIANIEAEDGVIMATGGFGANIDMTQKYNPDIDDRYNTTNVPGATGEGILMAKEIGADLVDMEFIQTYPTCNTQTGH
LSYVADTRFDGAILVNQEGERFVEELDRRDVISEAILDQTGSVAYLMWDNHIKENSNMDNYMTEFENLKETDQIIKADSI
EEAAEFFEIDVDELKNTVEQYNEYVKQGEDEDFNRRGDLLELKEGPYYIQEVAPAIHHTMGGIKINEEAQVIDTEGEIIE
GLYAAGEITGGIHGNNRLGGNAIADLIVFGRIAGDNVSK

Sequences:

>Translated_599_residues
MFQKRNLLLIMLTFVLLFTFSVGCNGDKEVGEEPGEEELALEEGTYEGSSYGHNAEIEVEVTIEDEDISDIEVLSHEESE
ILTDPVFEEIIPAIVENNNTNVDSISGATVTSLALVSAVEDALKEAGAEEYFEGEMVEVDSASEIADSTYDVVVVGGGGA
GLVSAIEAKSQGADVVLLEKMPYLGGNTLVSGGEFNAPNTWVQENPDIDDSVDQFVEDTLEGGDYEADEDLVQTLAENVT
EDAEWMKDYVGVEFVDDYLMHFGGHEVPRALYPIGGSGLELISSLEERALDDEIPIKFNTEAKELLTDEDGRVVGVKVED
HEGEIANIEAEDGVIMATGGFGANIDMTQKYNPDIDDRYNTTNVPGATGEGILMAKEIGADLVDMEFIQTYPTCNTQTGH
LSYVADTRFDGAILVNQEGERFVEELDRRDVISEAILDQTGSVAYLMWDNHIKENSNMDNYMTEFENLKETDQIIKADSI
EEAAEFFEIDVDELKNTVEQYNEYVKQGEDEDFNRRGDLLELKEGPYYIQEVAPAIHHTMGGIKINEEAQVIDTEGEIIE
GLYAAGEITGGIHGNNRLGGNAIADLIVFGRIAGDNVSK
>Mature_599_residues
MFQKRNLLLIMLTFVLLFTFSVGCNGDKEVGEEPGEEELALEEGTYEGSSYGHNAEIEVEVTIEDEDISDIEVLSHEESE
ILTDPVFEEIIPAIVENNNTNVDSISGATVTSLALVSAVEDALKEAGAEEYFEGEMVEVDSASEIADSTYDVVVVGGGGA
GLVSAIEAKSQGADVVLLEKMPYLGGNTLVSGGEFNAPNTWVQENPDIDDSVDQFVEDTLEGGDYEADEDLVQTLAENVT
EDAEWMKDYVGVEFVDDYLMHFGGHEVPRALYPIGGSGLELISSLEERALDDEIPIKFNTEAKELLTDEDGRVVGVKVED
HEGEIANIEAEDGVIMATGGFGANIDMTQKYNPDIDDRYNTTNVPGATGEGILMAKEIGADLVDMEFIQTYPTCNTQTGH
LSYVADTRFDGAILVNQEGERFVEELDRRDVISEAILDQTGSVAYLMWDNHIKENSNMDNYMTEFENLKETDQIIKADSI
EEAAEFFEIDVDELKNTVEQYNEYVKQGEDEDFNRRGDLLELKEGPYYIQEVAPAIHHTMGGIKINEEAQVIDTEGEIIE
GLYAAGEITGGIHGNNRLGGNAIADLIVFGRIAGDNVSK

Specific function: Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=456, Percent_Identity=25.219298245614, Blast_Score=109, Evalue=1e-23,
Organism=Escherichia coli, GI1788928, Length=481, Percent_Identity=25.7796257796258, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1790597, Length=417, Percent_Identity=27.0983213429257, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1786942, Length=476, Percent_Identity=27.7310924369748, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71986328, Length=468, Percent_Identity=34.4017094017094, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17505833, Length=489, Percent_Identity=26.7893660531697, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17550100, Length=477, Percent_Identity=25.7861635220126, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320788, Length=477, Percent_Identity=32.9140461215933, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6322511, Length=479, Percent_Identity=30.6889352818372, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6322701, Length=521, Percent_Identity=27.447216890595, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322416, Length=488, Percent_Identity=27.4590163934426, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17137288, Length=491, Percent_Identity=25.6619144602851, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24655642, Length=491, Percent_Identity=25.6619144602851, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24655647, Length=491, Percent_Identity=25.6619144602851, Blast_Score=103, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR010960
- InterPro:   IPR011031 [H]

Pfam domain/function: PF00890 FAD_binding_2 [H]

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 65607; Mature: 65607

Theoretical pI: Translated: 3.68; Mature: 3.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQKRNLLLIMLTFVLLFTFSVGCNGDKEVGEEPGEEELALEEGTYEGSSYGHNAEIEVE
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHEEECCCCCCCCCCCCCCEEEEE
VTIEDEDISDIEVLSHEESEILTDPVFEEIIPAIVENNNTNVDSISGATVTSLALVSAVE
EEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
DALKEAGAEEYFEGEMVEVDSASEIADSTYDVVVVGGGGAGLVSAIEAKSQGADVVLLEK
HHHHHCCCHHHCCCCEEEECCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEC
MPYLGGNTLVSGGEFNAPNTWVQENPDIDDSVDQFVEDTLEGGDYEADEDLVQTLAENVT
CCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
EDAEWMKDYVGVEFVDDYLMHFGGHEVPRALYPIGGSGLELISSLEERALDDEIPIKFNT
HHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCEEECC
EAKELLTDEDGRVVGVKVEDHEGEIANIEAEDGVIMATGGFGANIDMTQKYNPDIDDRYN
CHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
TTNVPGATGEGILMAKEIGADLVDMEFIQTYPTCNTQTGHLSYVADTRFDGAILVNQEGE
CCCCCCCCCCCEEEEHHHCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEECCCHH
RFVEELDRRDVISEAILDQTGSVAYLMWDNHIKENSNMDNYMTEFENLKETDQIIKADSI
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
EEAAEFFEIDVDELKNTVEQYNEYVKQGEDEDFNRRGDLLELKEGPYYIQEVAPAIHHTM
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
GGIKINEEAQVIDTEGEIIEGLYAAGEITGGIHGNNRLGGNAIADLIVFGRIAGDNVSK
CCEEECCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFQKRNLLLIMLTFVLLFTFSVGCNGDKEVGEEPGEEELALEEGTYEGSSYGHNAEIEVE
CCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHEEECCCCCCCCCCCCCCEEEEE
VTIEDEDISDIEVLSHEESEILTDPVFEEIIPAIVENNNTNVDSISGATVTSLALVSAVE
EEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
DALKEAGAEEYFEGEMVEVDSASEIADSTYDVVVVGGGGAGLVSAIEAKSQGADVVLLEK
HHHHHCCCHHHCCCCEEEECCHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEC
MPYLGGNTLVSGGEFNAPNTWVQENPDIDDSVDQFVEDTLEGGDYEADEDLVQTLAENVT
CCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
EDAEWMKDYVGVEFVDDYLMHFGGHEVPRALYPIGGSGLELISSLEERALDDEIPIKFNT
HHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCEEECC
EAKELLTDEDGRVVGVKVEDHEGEIANIEAEDGVIMATGGFGANIDMTQKYNPDIDDRYN
CHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
TTNVPGATGEGILMAKEIGADLVDMEFIQTYPTCNTQTGHLSYVADTRFDGAILVNQEGE
CCCCCCCCCCCEEEEHHHCCCHHHHHHHHHCCCCCCCCCCEEEEECCCCCCEEEECCCHH
RFVEELDRRDVISEAILDQTGSVAYLMWDNHIKENSNMDNYMTEFENLKETDQIIKADSI
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCH
EEAAEFFEIDVDELKNTVEQYNEYVKQGEDEDFNRRGDLLELKEGPYYIQEVAPAIHHTM
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
GGIKINEEAQVIDTEGEIIEGLYAAGEITGGIHGNNRLGGNAIADLIVFGRIAGDNVSK
CCEEECCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10455032; 10581549 [H]