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The map label for this gene is tagO [H]

Identifier: 188586984

GI number: 188586984

Start: 2537313

End: 2538251

Strand: Reverse

Name: tagO [H]

Synonym: Nther_2376

Alternate gene names: 188586984

Gene position: 2538251-2537313 (Counterclockwise)

Preceding gene: 188586985

Following gene: 188586983

Centisome position: 80.18

GC content: 38.34

Gene sequence:

>939_bases
ATGGAGCTCTACCTTAAAGTTGCGGTAACTTCTGCCGCCTTAAGTTTAATCATGACACCACTATTGAGAAAAATATCATA
TAAGGTGGGGGCTGTGGACCAGCCAAAGGAAAGCAGAAAAATTCACAACCATGTTATGCCTAGGTTAGGTGGTCCTGCCA
TATTTTTGAGTTTTTTGATTTCATTAATAATGTACGTACCATTAGAAACTGAATTTTATGGGCTCTTGATGGGCTCAATA
TTGATTTTAGTTATAGGAATGCTTGACGATATATATGGATTGTCTCCGCTAATAAAACTGGGTGGACAGGTGGCAGCGGT
TCTGGTATTTATAGCCTTCGGAAATCAGGTAGAGTTCTTAACCAATCCCTTTGACGGCTTGTTTTATTTGGGAGTTTTAA
GTATCCCTGTGACCGTAATGTGGATGGTGGGAGTCACAAATGCTCTCAACTTGATTGACGGTTTAGATGGATTGGCTTCA
GGAGTATCAGCTATAGCGTTAACGGCTTTTGCCATTATAGCCGTTCAAAACGAACAAATGTTAGTTGCCTTGACAGCTTT
AGCTTTATTGGGTGGTATCCTAGGTTTTTTAAAATACAACTTTTACCCTGCAAAAATTTTCTTAGGTGATTCAGGTTCTC
TGTTACTTGGTTATATGATTTCCGCTTTATCAGTTATGGGCCTATTGAAAAGTGTTACTATGGTGACTTTTATCATCCCC
ATGCTCCTTTTAGGAGTACCTATACTAGACACATTCTTTGCCATATTGAGAAGATACTGGCATAAAAGACCAATTTTTCA
GGCTGATAAAGGTCATTTACATCACAGATTATTGAATTTGGGAATGAGTCATAAACAAGCTGTTCTATTTATTTACTTGA
TAAGTGTCGGTTTTGGAATTGGAGCGGTGCTCTTCTTTCAAAATGGCACAGGATTTTAG

Upstream 100 bases:

>100_bases
CTGAAGGTAAACAAAAGCTAGATAAGTTAAGAGCCTAAAAATGGCAGAGATAATGCAATAGAAACATCAAAGAAAGGTTT
AGAACTGGAGGTTATGACCT

Downstream 100 bases:

>100_bases
AAAATACATAAACCGGCCTCTTAAGAAGAGAGGCTGGTTATTTGTTTGCCCGGCATGCCTGCCGCGCCGATGGGTTGAAA
GAAACCCTGTCACCTAACCA

Product: glycosyl transferase family 4

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MELYLKVAVTSAALSLIMTPLLRKISYKVGAVDQPKESRKIHNHVMPRLGGPAIFLSFLISLIMYVPLETEFYGLLMGSI
LILVIGMLDDIYGLSPLIKLGGQVAAVLVFIAFGNQVEFLTNPFDGLFYLGVLSIPVTVMWMVGVTNALNLIDGLDGLAS
GVSAIALTAFAIIAVQNEQMLVALTALALLGGILGFLKYNFYPAKIFLGDSGSLLLGYMISALSVMGLLKSVTMVTFIIP
MLLLGVPILDTFFAILRRYWHKRPIFQADKGHLHHRLLNLGMSHKQAVLFIYLISVGFGIGAVLFFQNGTGF

Sequences:

>Translated_312_residues
MELYLKVAVTSAALSLIMTPLLRKISYKVGAVDQPKESRKIHNHVMPRLGGPAIFLSFLISLIMYVPLETEFYGLLMGSI
LILVIGMLDDIYGLSPLIKLGGQVAAVLVFIAFGNQVEFLTNPFDGLFYLGVLSIPVTVMWMVGVTNALNLIDGLDGLAS
GVSAIALTAFAIIAVQNEQMLVALTALALLGGILGFLKYNFYPAKIFLGDSGSLLLGYMISALSVMGLLKSVTMVTFIIP
MLLLGVPILDTFFAILRRYWHKRPIFQADKGHLHHRLLNLGMSHKQAVLFIYLISVGFGIGAVLFFQNGTGF
>Mature_312_residues
MELYLKVAVTSAALSLIMTPLLRKISYKVGAVDQPKESRKIHNHVMPRLGGPAIFLSFLISLIMYVPLETEFYGLLMGSI
LILVIGMLDDIYGLSPLIKLGGQVAAVLVFIAFGNQVEFLTNPFDGLFYLGVLSIPVTVMWMVGVTNALNLIDGLDGLAS
GVSAIALTAFAIIAVQNEQMLVALTALALLGGILGFLKYNFYPAKIFLGDSGSLLLGYMISALSVMGLLKSVTMVTFIIP
MLLLGVPILDTFFAILRRYWHKRPIFQADKGHLHHRLLNLGMSHKQAVLFIYLISVGFGIGAVLFFQNGTGF

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=286, Percent_Identity=25.5244755244755, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786275, Length=328, Percent_Identity=27.4390243902439, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 33958; Mature: 33958

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELYLKVAVTSAALSLIMTPLLRKISYKVGAVDQPKESRKIHNHVMPRLGGPAIFLSFLI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SLIMYVPLETEFYGLLMGSILILVIGMLDDIYGLSPLIKLGGQVAAVLVFIAFGNQVEFL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHCCCCHHH
TNPFDGLFYLGVLSIPVTVMWMVGVTNALNLIDGLDGLASGVSAIALTAFAIIAVQNEQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LVALTALALLGGILGFLKYNFYPAKIFLGDSGSLLLGYMISALSVMGLLKSVTMVTFIIP
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLLGVPILDTFFAILRRYWHKRPIFQADKGHLHHRLLNLGMSHKQAVLFIYLISVGFGI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GAVLFFQNGTGF
HHEEEECCCCCC
>Mature Secondary Structure
MELYLKVAVTSAALSLIMTPLLRKISYKVGAVDQPKESRKIHNHVMPRLGGPAIFLSFLI
CCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
SLIMYVPLETEFYGLLMGSILILVIGMLDDIYGLSPLIKLGGQVAAVLVFIAFGNQVEFL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHCCCCHHH
TNPFDGLFYLGVLSIPVTVMWMVGVTNALNLIDGLDGLASGVSAIALTAFAIIAVQNEQM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LVALTALALLGGILGFLKYNFYPAKIFLGDSGSLLLGYMISALSVMGLLKSVTMVTFIIP
HHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLLGVPILDTFFAILRRYWHKRPIFQADKGHLHHRLLNLGMSHKQAVLFIYLISVGFGI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GAVLFFQNGTGF
HHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]