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The map label for this gene is yrrC [H]

Identifier: 188586920

GI number: 188586920

Start: 2456652

End: 2458832

Strand: Reverse

Name: yrrC [H]

Synonym: Nther_2311

Alternate gene names: 188586920

Gene position: 2458832-2456652 (Counterclockwise)

Preceding gene: 188586921

Following gene: 188586918

Centisome position: 77.67

GC content: 40.76

Gene sequence:

>2181_bases
ATGGAAATGGCTCAAATCGAGGGGATAATTAAACGAGTAACATATCATAATCCGGAAAATATGTTTACAGTAGCCAAACT
GGTCACTCAAGAGACGAGAAATGAAATTACTATAGTAGGCAATATGCCTCATTTGACTCCAGGAGAACGCTTGGACCTTT
CCGGAGAATATGTTGATCATAAAAAATTCGGGAAACAGTTCCAGGTTGATAGCTATGAAATAAAATTACCTGTAACAGTA
GATGGATTAATTAAATTTCTCAGTTCGGGGATGATTAAAGGGATTGGCCCCAAAACAGCGGAAAGTCTGGTGGAGCACTT
CGGTAAAGAAGTGCTCCAAGTTATTGAAAATACACCGGAAAAGTTACAGGAAGTACCCGGAATCGGCAAGGAAAAAGCAG
CTCAGATATCCAGGGGATTCCAAGAGCACAAGCAGATTAAAGATATTATGGTATTTTTACAGGAATTTGGAGTAAGTCCT
GCTTTTGCTCTGAAAATTTACCGCCGTTTCGGTGACAATACAATTCAAAAGGTATCTGAAAATCCATATTCACTTGCTAG
AGAGGTCTTTGGGATTGGATTTAAAACTGCTGATAAAATAGCCCGGGAAATGGGTGTTTCAGTAGACTCCGAGGAGCGAG
CCAAGGCTGCTGTAGTCTACCTATTAGAAGAGAAATCTCAAGATGGTAATACTTTTTTGAAAAGAGAAGAATTAATAGAA
GCATTAAAGGAATTGGAAGTAGAGAATGTCAATTTAAATTCTGTGCTGGAAGAATTAGTCGAAGAAAAAGAAATAGTGGT
TGAAAATATCCCTGAAGCAGGTGAGCTGATTTATCCGGCTCCCTTCTTTTTTGCTGAACAGGGAATTGCCAGTAGATTAA
AAAGGTTAAAAGATGGAGTGGACAGGGAACTATTTCCTAGGATCCAGAAAATAGCAGAAAAGTATTTGGAAGAGCAGGCA
AATTTAGTTCTTTCTCCGGAACAGCATCAGGTGATAAAGCAGGTGCCTGAAACAGGTTTGATGGTGGTCACAGGTGGACC
TGGTACAGGTAAAACAACAGTGATCAAGTGCTTGATGGATATATTTCAAAAAGCCGGACAGAAAGTTATGCTCGCTGCTC
CTACGGGTAGAGCTGCCAAGCGTATGAGTGAAGCCACAGGTGATGAAGCTAAAACTATTCACCGGTTGCTTGAATTTACC
TATGATAAGGAAGAGGGAATGAAATTTCAGCGCAATCAAGACCGTCCACTGAAAGGTGATCTATTAATTGTGGACGAGGC
ATCCATGATAGATACGATTTTAATGAACAATCTGTTAAAGGCAATATCACCTGGGACTCGACTGGTCCTGGTAGGGGATA
CTGATCAACTACCCTCAGTTGGGGCTGGCAATGTCCTTCAGGATATCATCGAATCAGGACGGATACCTTTGGTCAGGTTA
AAGAGAGTTTTTCGCCAGGCCAGAGAAAGTATGGTTGTGGTCAACGCTCATAGAATAAATGAGGGGAAGTTTCCCATTTT
GAATGCCAAGGGAAAGGACTTTTATTTTTTACCCAGAGAAGAACCTGAAGATGTTGTTAAGACAATTATTTCACTGTGTG
CCAAGCGCTTGCCTAACTACAACGGTTATCACCCTGTAAACGATATTCAGGTTCTGTCTCCCATGAGAAGGACAGTAACG
GGGGTAGAAAATTTGAATCAATCTCTTCAAAAAGTTCTCAATCCTCCGCAAAAAAATAAGGCTGAAATTAACTTTGGTGG
TGCTTGTTATCGAACAGGGGATAAAGTCATGCAGGTCAAAAACGATTATGAAAAGAATGTTTTTAATGGAGATACAGGAA
TTGTAACCAAGGTGGATGCGGAAGAAAATGTAGTTAACGTTAGATATGGGCATGGTGAAGAGATAGCCTATGAAGGCAGG
GAACTAGACGCTTTAGTCCACGCCTATTGCATTAGTGTGCACAAGAGTCAGGGAAGTGAATACCCGGTGGTTGTTTTGCC
AGTGACAACACAGCATTACATCATGTTACAGAGAAATCTACTGTACACAGCTGTTACTAGAGCTAAATCTCTAGTAGTTT
TGGTCGGGACCAAAAAATCAATTGGGATAGCAATTTCAAACAAAAAAACCGATGAGCGAAATACCTTCCTACAGCACAGA
ATTGCGGTCTATGAGGTTTAA

Upstream 100 bases:

>100_bases
CAAGGTAAAAACAGGGTCAGCATGTTTAAAAAAATAACTGAACTTCATTCAGTACAGGACGATGAAAAAAAAATTGTGGG
ATTCCCCAATAGAGGGGTGG

Downstream 100 bases:

>100_bases
TATCTTAACGATTTTAAAGAGGAAATAAATACAATAAAGAAGCCTGCCATCTGTTAAAACAGTTTGGCAGGCTCAATTTA
TGTTTAATCGTTTTTGTTTG

Product: helicase, RecD/TraA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MEMAQIEGIIKRVTYHNPENMFTVAKLVTQETRNEITIVGNMPHLTPGERLDLSGEYVDHKKFGKQFQVDSYEIKLPVTV
DGLIKFLSSGMIKGIGPKTAESLVEHFGKEVLQVIENTPEKLQEVPGIGKEKAAQISRGFQEHKQIKDIMVFLQEFGVSP
AFALKIYRRFGDNTIQKVSENPYSLAREVFGIGFKTADKIAREMGVSVDSEERAKAAVVYLLEEKSQDGNTFLKREELIE
ALKELEVENVNLNSVLEELVEEKEIVVENIPEAGELIYPAPFFFAEQGIASRLKRLKDGVDRELFPRIQKIAEKYLEEQA
NLVLSPEQHQVIKQVPETGLMVVTGGPGTGKTTVIKCLMDIFQKAGQKVMLAAPTGRAAKRMSEATGDEAKTIHRLLEFT
YDKEEGMKFQRNQDRPLKGDLLIVDEASMIDTILMNNLLKAISPGTRLVLVGDTDQLPSVGAGNVLQDIIESGRIPLVRL
KRVFRQARESMVVVNAHRINEGKFPILNAKGKDFYFLPREEPEDVVKTIISLCAKRLPNYNGYHPVNDIQVLSPMRRTVT
GVENLNQSLQKVLNPPQKNKAEINFGGACYRTGDKVMQVKNDYEKNVFNGDTGIVTKVDAEENVVNVRYGHGEEIAYEGR
ELDALVHAYCISVHKSQGSEYPVVVLPVTTQHYIMLQRNLLYTAVTRAKSLVVLVGTKKSIGIAISNKKTDERNTFLQHR
IAVYEV

Sequences:

>Translated_726_residues
MEMAQIEGIIKRVTYHNPENMFTVAKLVTQETRNEITIVGNMPHLTPGERLDLSGEYVDHKKFGKQFQVDSYEIKLPVTV
DGLIKFLSSGMIKGIGPKTAESLVEHFGKEVLQVIENTPEKLQEVPGIGKEKAAQISRGFQEHKQIKDIMVFLQEFGVSP
AFALKIYRRFGDNTIQKVSENPYSLAREVFGIGFKTADKIAREMGVSVDSEERAKAAVVYLLEEKSQDGNTFLKREELIE
ALKELEVENVNLNSVLEELVEEKEIVVENIPEAGELIYPAPFFFAEQGIASRLKRLKDGVDRELFPRIQKIAEKYLEEQA
NLVLSPEQHQVIKQVPETGLMVVTGGPGTGKTTVIKCLMDIFQKAGQKVMLAAPTGRAAKRMSEATGDEAKTIHRLLEFT
YDKEEGMKFQRNQDRPLKGDLLIVDEASMIDTILMNNLLKAISPGTRLVLVGDTDQLPSVGAGNVLQDIIESGRIPLVRL
KRVFRQARESMVVVNAHRINEGKFPILNAKGKDFYFLPREEPEDVVKTIISLCAKRLPNYNGYHPVNDIQVLSPMRRTVT
GVENLNQSLQKVLNPPQKNKAEINFGGACYRTGDKVMQVKNDYEKNVFNGDTGIVTKVDAEENVVNVRYGHGEEIAYEGR
ELDALVHAYCISVHKSQGSEYPVVVLPVTTQHYIMLQRNLLYTAVTRAKSLVVLVGTKKSIGIAISNKKTDERNTFLQHR
IAVYEV
>Mature_726_residues
MEMAQIEGIIKRVTYHNPENMFTVAKLVTQETRNEITIVGNMPHLTPGERLDLSGEYVDHKKFGKQFQVDSYEIKLPVTV
DGLIKFLSSGMIKGIGPKTAESLVEHFGKEVLQVIENTPEKLQEVPGIGKEKAAQISRGFQEHKQIKDIMVFLQEFGVSP
AFALKIYRRFGDNTIQKVSENPYSLAREVFGIGFKTADKIAREMGVSVDSEERAKAAVVYLLEEKSQDGNTFLKREELIE
ALKELEVENVNLNSVLEELVEEKEIVVENIPEAGELIYPAPFFFAEQGIASRLKRLKDGVDRELFPRIQKIAEKYLEEQA
NLVLSPEQHQVIKQVPETGLMVVTGGPGTGKTTVIKCLMDIFQKAGQKVMLAAPTGRAAKRMSEATGDEAKTIHRLLEFT
YDKEEGMKFQRNQDRPLKGDLLIVDEASMIDTILMNNLLKAISPGTRLVLVGDTDQLPSVGAGNVLQDIIESGRIPLVRL
KRVFRQARESMVVVNAHRINEGKFPILNAKGKDFYFLPREEPEDVVKTIISLCAKRLPNYNGYHPVNDIQVLSPMRRTVT
GVENLNQSLQKVLNPPQKNKAEINFGGACYRTGDKVMQVKNDYEKNVFNGDTGIVTKVDAEENVVNVRYGHGEEIAYEGR
ELDALVHAYCISVHKSQGSEYPVVVLPVTTQHYIMLQRNLLYTAVTRAKSLVVLVGTKKSIGIAISNKKTDERNTFLQHR
IAVYEV

Specific function: Exhibits Several Catalytic Activities, Including ATP-Dependent Exonuclease, ATP-Stimulated Endonuclease, ATP-Dependent Unwinding And DNA-Dependent ATPase Activities. Strand Cleavage Occurs 5' To 3' During The Unwinding Of Duplex DNA At Chi Sequences, Whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32455236, Length=519, Percent_Identity=24.0847784200385, Blast_Score=80, Evalue=1e-14,
Organism=Escherichia coli, GI1789182, Length=430, Percent_Identity=27.906976744186, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR006345 [H]

Pfam domain/function: NA

EC number: 3.1.11.5

Molecular weight: Translated: 81436; Mature: 81436

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMAQIEGIIKRVTYHNPENMFTVAKLVTQETRNEITIVGNMPHLTPGERLDLSGEYVDH
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHH
KKFGKQFQVDSYEIKLPVTVDGLIKFLSSGMIKGIGPKTAESLVEHFGKEVLQVIENTPE
HHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
KLQEVPGIGKEKAAQISRGFQEHKQIKDIMVFLQEFGVSPAFALKIYRRFGDNTIQKVSE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCC
NPYSLAREVFGIGFKTADKIAREMGVSVDSEERAKAAVVYLLEEKSQDGNTFLKREELIE
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCCHHHHHHHHHH
ALKELEVENVNLNSVLEELVEEKEIVVENIPEAGELIYPAPFFFAEQGIASRLKRLKDGV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCC
DRELFPRIQKIAEKYLEEQANLVLSPEQHQVIKQVPETGLMVVTGGPGTGKTTVIKCLMD
CHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
IFQKAGQKVMLAAPTGRAAKRMSEATGDEAKTIHRLLEFTYDKEEGMKFQRNQDRPLKGD
HHHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCC
LLIVDEASMIDTILMNNLLKAISPGTRLVLVGDTDQLPSVGAGNVLQDIIESGRIPLVRL
EEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHH
KRVFRQARESMVVVNAHRINEGKFPILNAKGKDFYFLPREEPEDVVKTIISLCAKRLPNY
HHHHHHHHHCEEEEEEEECCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCC
NGYHPVNDIQVLSPMRRTVTGVENLNQSLQKVLNPPQKNKAEINFGGACYRTGDKVMQVK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCHHHHHHH
NDYEKNVFNGDTGIVTKVDAEENVVNVRYGHGEEIAYEGRELDALVHAYCISVHKSQGSE
HHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCC
YPVVVLPVTTQHYIMLQRNLLYTAVTRAKSLVVLVGTKKSIGIAISNKKTDERNTFLQHR
CCEEEEECCCCEEHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEECCCCCCHHHHHHHHH
IAVYEV
HHEECC
>Mature Secondary Structure
MEMAQIEGIIKRVTYHNPENMFTVAKLVTQETRNEITIVGNMPHLTPGERLDLSGEYVDH
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHH
KKFGKQFQVDSYEIKLPVTVDGLIKFLSSGMIKGIGPKTAESLVEHFGKEVLQVIENTPE
HHHCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
KLQEVPGIGKEKAAQISRGFQEHKQIKDIMVFLQEFGVSPAFALKIYRRFGDNTIQKVSE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHCC
NPYSLAREVFGIGFKTADKIAREMGVSVDSEERAKAAVVYLLEEKSQDGNTFLKREELIE
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCCHHHHHHHHHH
ALKELEVENVNLNSVLEELVEEKEIVVENIPEAGELIYPAPFFFAEQGIASRLKRLKDGV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHCCC
DRELFPRIQKIAEKYLEEQANLVLSPEQHQVIKQVPETGLMVVTGGPGTGKTTVIKCLMD
CHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
IFQKAGQKVMLAAPTGRAAKRMSEATGDEAKTIHRLLEFTYDKEEGMKFQRNQDRPLKGD
HHHHCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCC
LLIVDEASMIDTILMNNLLKAISPGTRLVLVGDTDQLPSVGAGNVLQDIIESGRIPLVRL
EEEEECHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHH
KRVFRQARESMVVVNAHRINEGKFPILNAKGKDFYFLPREEPEDVVKTIISLCAKRLPNY
HHHHHHHHHCEEEEEEEECCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCC
NGYHPVNDIQVLSPMRRTVTGVENLNQSLQKVLNPPQKNKAEINFGGACYRTGDKVMQVK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEEECCHHHHHHH
NDYEKNVFNGDTGIVTKVDAEENVVNVRYGHGEEIAYEGRELDALVHAYCISVHKSQGSE
HHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCC
YPVVVLPVTTQHYIMLQRNLLYTAVTRAKSLVVLVGTKKSIGIAISNKKTDERNTFLQHR
CCEEEEECCCCEEHHHHHHHHHHHHHHHCEEEEEEECCCCEEEEECCCCCCHHHHHHHHH
IAVYEV
HHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: DNA-dependent ATPase activity; Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]