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The map label for this gene is yisQ [H]

Identifier: 188586904

GI number: 188586904

Start: 2439863

End: 2441290

Strand: Reverse

Name: yisQ [H]

Synonym: Nther_2295

Alternate gene names: 188586904

Gene position: 2441290-2439863 (Counterclockwise)

Preceding gene: 188586905

Following gene: 188586903

Centisome position: 77.12

GC content: 43.42

Gene sequence:

>1428_bases
ATGCTGCGACAGCTGTCCGGTGAAGAACGCCGGCTTTTAATTTTAGAAGGTAGTCTTTATAAAGCTGTGTTTTTCTTAGC
CTGGCCTATGGTTATTCAGTCCTTGATGATGATTTTGGTAGGAGCAGTAGATATGATGATGGTAGGAGCTCTGGGTTCCG
ATGCTGTTGGTGCTGTAGGCATGGCCAGGCAGGTGATTCAAATTATTGGAATTTCCATTATGGCAGTAGGCGTAGGATCC
ACAGCCACTATAGCCCGGTATTACGGATATAATGATATTAAAGGAGCAGTTAATGCTACTGGTCAGGCCTTGTATCTATT
ATTCTTATTTTCTTTAATTATTACCACAGTTGGCCTGGTGTTTTCTGAAGGAATTATGCATCTACTAGGTGCTGAAGGGG
ATTTATTAACACTGGGTACTGGCTATTTACAGATCTTTTTTGCTGGCTCATTATTTTTCTTAGGAAATTTTACACTGCGA
TCAATTTTCCAGGGAACCGGTGATACCAAAACACCCACACAAATCGATGTGGCTACTAACTTGCTCAATATAGCTTTAAA
TTATTTATTGATTTTTGGTGTCGGCCCAGTACCAGCTTTGGGAGTGCCCGGTGCGGCACTGGGCAGTTTATTATCCAGGG
TATTTGCTTTTTCTGTTGGGCTGTATGCTTTAAAACACCGGGGTTTCTATTATATTCCCTCTGTGAAGGAATTCATGGAA
CTGAGCACTCATAAGATGAAACAAATTCTTCGCATCGGAATTCCTGCTGCTCTGCAGGGAATAACGAGAAGTGGAGGAAA
TATAGTGGTCTTGGGGATGATTGCCAGGACAGCTGCCGGAAATGATGCGGTCTCAGGTTACAGTGTGGGATTAATGGTTT
TTGCCTTCGCCTTGTTTCCTGCTCAGGCAGTGGGTAAATCTGCAGCTACTATCATTGGTATGAATTTGGGAGCTTATCAA
AAGGATAGAGCTGAGGAAAGCGGTTGGAAGTGTACTGGCATGGGAATGGGCATCATCGCCCTGTTTTCCTTAATAGTGTT
TATCTTTGCTCCCCAGTTCATCCGCTTATTTGTAGATGATCCGGAAGTTGTGCGGATTGGTGCGAGCTTTGTCAGAATCC
TGGCTGTAGTGGAGCCAATCCATGCCATGGGTTTAATACTGGCAAATGCTTTGCACGGTGCAGGAGAAACCGTGGTTCCC
TTCTATATCTCCTTACTATCTTGGGTGATATTACGAGTGCCCTTCGCATATTTCTTTGCCTTTGGCTTGGGTTTTCAAGA
AACGGGTATCTGGATTGGAATAGCTGTAACACAGGTGATTCAAGGTGTATTGACTGCCTTAAAATTCCGAGAAGGTAAGT
GGAAGGACAAAGAAATTACAGAAAGCTCCTCTGAAAATTTTTCCAGTAAAGTGACAGGAAAGGCGTAA

Upstream 100 bases:

>100_bases
TAGAATTTTATGATTATTTCAAGGAATTATAGTTTCGTCTCACGAAATATAATTATATACATAAATATATACATAAAACT
GAGAGCAAAGAGGGATTAAT

Downstream 100 bases:

>100_bases
CTTATGGCGAATACCTTATATAGTAGTAATAATTTTCTGGCTATTCACCATAAGTTCTATGTGGATGATAAAAAATTAGG
GGGGTATGGTTATGTTTAGA

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MLRQLSGEERRLLILEGSLYKAVFFLAWPMVIQSLMMILVGAVDMMMVGALGSDAVGAVGMARQVIQIIGISIMAVGVGS
TATIARYYGYNDIKGAVNATGQALYLLFLFSLIITTVGLVFSEGIMHLLGAEGDLLTLGTGYLQIFFAGSLFFLGNFTLR
SIFQGTGDTKTPTQIDVATNLLNIALNYLLIFGVGPVPALGVPGAALGSLLSRVFAFSVGLYALKHRGFYYIPSVKEFME
LSTHKMKQILRIGIPAALQGITRSGGNIVVLGMIARTAAGNDAVSGYSVGLMVFAFALFPAQAVGKSAATIIGMNLGAYQ
KDRAEESGWKCTGMGMGIIALFSLIVFIFAPQFIRLFVDDPEVVRIGASFVRILAVVEPIHAMGLILANALHGAGETVVP
FYISLLSWVILRVPFAYFFAFGLGFQETGIWIGIAVTQVIQGVLTALKFREGKWKDKEITESSSENFSSKVTGKA

Sequences:

>Translated_475_residues
MLRQLSGEERRLLILEGSLYKAVFFLAWPMVIQSLMMILVGAVDMMMVGALGSDAVGAVGMARQVIQIIGISIMAVGVGS
TATIARYYGYNDIKGAVNATGQALYLLFLFSLIITTVGLVFSEGIMHLLGAEGDLLTLGTGYLQIFFAGSLFFLGNFTLR
SIFQGTGDTKTPTQIDVATNLLNIALNYLLIFGVGPVPALGVPGAALGSLLSRVFAFSVGLYALKHRGFYYIPSVKEFME
LSTHKMKQILRIGIPAALQGITRSGGNIVVLGMIARTAAGNDAVSGYSVGLMVFAFALFPAQAVGKSAATIIGMNLGAYQ
KDRAEESGWKCTGMGMGIIALFSLIVFIFAPQFIRLFVDDPEVVRIGASFVRILAVVEPIHAMGLILANALHGAGETVVP
FYISLLSWVILRVPFAYFFAFGLGFQETGIWIGIAVTQVIQGVLTALKFREGKWKDKEITESSSENFSSKVTGKA
>Mature_475_residues
MLRQLSGEERRLLILEGSLYKAVFFLAWPMVIQSLMMILVGAVDMMMVGALGSDAVGAVGMARQVIQIIGISIMAVGVGS
TATIARYYGYNDIKGAVNATGQALYLLFLFSLIITTVGLVFSEGIMHLLGAEGDLLTLGTGYLQIFFAGSLFFLGNFTLR
SIFQGTGDTKTPTQIDVATNLLNIALNYLLIFGVGPVPALGVPGAALGSLLSRVFAFSVGLYALKHRGFYYIPSVKEFME
LSTHKMKQILRIGIPAALQGITRSGGNIVVLGMIARTAAGNDAVSGYSVGLMVFAFALFPAQAVGKSAATIIGMNLGAYQ
KDRAEESGWKCTGMGMGIIALFSLIVFIFAPQFIRLFVDDPEVVRIGASFVRILAVVEPIHAMGLILANALHGAGETVVP
FYISLLSWVILRVPFAYFFAFGLGFQETGIWIGIAVTQVIQGVLTALKFREGKWKDKEITESSSENFSSKVTGKA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=458, Percent_Identity=26.6375545851528, Blast_Score=131, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50873; Mature: 50873

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRQLSGEERRLLILEGSLYKAVFFLAWPMVIQSLMMILVGAVDMMMVGALGSDAVGAVG
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MARQVIQIIGISIMAVGVGSTATIARYYGYNDIKGAVNATGQALYLLFLFSLIITTVGLV
HHHHHHHHHHHHHEEECCCCHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FSEGIMHLLGAEGDLLTLGTGYLQIFFAGSLFFLGNFTLRSIFQGTGDTKTPTQIDVATN
HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LLNIALNYLLIFGVGPVPALGVPGAALGSLLSRVFAFSVGLYALKHRGFYYIPSVKEFME
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHH
LSTHKMKQILRIGIPAALQGITRSGGNIVVLGMIARTAAGNDAVSGYSVGLMVFAFALFP
HHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHH
AQAVGKSAATIIGMNLGAYQKDRAEESGWKCTGMGMGIIALFSLIVFIFAPQFIRLFVDD
HHHHCCCHHEEEECCCCCCCHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
PEVVRIGASFVRILAVVEPIHAMGLILANALHGAGETVVPFYISLLSWVILRVPFAYFFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGLGFQETGIWIGIAVTQVIQGVLTALKFREGKWKDKEITESSSENFSSKVTGKA
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRQLSGEERRLLILEGSLYKAVFFLAWPMVIQSLMMILVGAVDMMMVGALGSDAVGAVG
CCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MARQVIQIIGISIMAVGVGSTATIARYYGYNDIKGAVNATGQALYLLFLFSLIITTVGLV
HHHHHHHHHHHHHEEECCCCHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
FSEGIMHLLGAEGDLLTLGTGYLQIFFAGSLFFLGNFTLRSIFQGTGDTKTPTQIDVATN
HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LLNIALNYLLIFGVGPVPALGVPGAALGSLLSRVFAFSVGLYALKHRGFYYIPSVKEFME
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHH
LSTHKMKQILRIGIPAALQGITRSGGNIVVLGMIARTAAGNDAVSGYSVGLMVFAFALFP
HHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHH
AQAVGKSAATIIGMNLGAYQKDRAEESGWKCTGMGMGIIALFSLIVFIFAPQFIRLFVDD
HHHHCCCHHEEEECCCCCCCHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
PEVVRIGASFVRILAVVEPIHAMGLILANALHGAGETVVPFYISLLSWVILRVPFAYFFA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGLGFQETGIWIGIAVTQVIQGVLTALKFREGKWKDKEITESSSENFSSKVTGKA
HCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]