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The map label for this gene is mcp4 [H]

Identifier: 188586873

GI number: 188586873

Start: 2407639

End: 2409453

Strand: Reverse

Name: mcp4 [H]

Synonym: Nther_2264

Alternate gene names: 188586873

Gene position: 2409453-2407639 (Counterclockwise)

Preceding gene: 188586874

Following gene: 188586872

Centisome position: 76.11

GC content: 40.88

Gene sequence:

>1815_bases
ATGAAAGGCACAGTAGTTCTCGCCTGGATTAATAGTTTAAAGGATTTGTATGGAGAAGACCAAGTAACTCAGGTACTTTC
AGAATTGGGATGGGAAGGTGATGAAATTATCACACCCACCATGAATGTATCTGATCGGGATGCCCGTGGACTGATAGAAA
AAATGGCAGAAAAACAAGGTTCTAGTAGTTCCCATGTTTTTAGAAAGTTGGGAAGAAAAAATATCTGGTCCTTTGCTGAA
TTGTTTCCGTCTTATTTTGATCAGAGTACGGCAAAGGAATTCCTAATGATGATGGATGAAGTCCACCGCCAGCTTACCAA
AATGATCTCTGGTGCAACTCCCCCGGGTCTTGTGGCTGAAGAACTTTCTCCAAATACTATTAAAATTAAATATGTTTCTA
ACCGGGGTTTATTTGATTATTTCTTAGGACTTCTGGAAGGAGTCGGAGATTATTTTGATGAGGAAATCAATTTTGAAGAA
CTGGATCGGGGAGAAGACTCCAATGGAGAACAATATTTAGATGTAAAAATTACTACAGAACAAGCTACAGCTGGAATTAA
AGAATTTCCCTTGAGCCGTTTCTTGTCCTTGGGAATAATCAGAGGAGTACCAGGTAAAATTGCTCTTTCAAGTAGTGTTG
TTATAACAATAATAGCTGCTGCCTTGAATGGCTTTCAACTCGACACCAATCTGGCAGTGATTCTGGTGGCTAGTTTTGCA
GTTATATACGGTTCAGCCAAGATTGCTCTGGCGCCTTTAGATGTAGTCAGAAATGAATTGAACAAGTTGAAGGAACTGGA
TTTTTCTCAGGCCCTCAGGGTAAGTTCCGGTGACTACATAGAAACACTACAAAATGATTTATTTGAGTCCAAGACTAATA
TCAAAAAAGGTTTATTATTTTTAAAAGGCGGTACAGATGATTTATATAAATTTGTTGAGCGCTACGGAAATGTATCCGAT
AATATGAAAGAGCTGTCGGGTGACATTTCCCAAATGGTGCAGGAAGTTTCTCAAGGAGCTATTCAACAAGCGGAAGAAAC
AGAAGGTTCCGTTAACAGTCTGCAAAGTAATGTAGAAACAATCCAATCCATTGCCAATGAAGAACTTGAAGATAAAGAAG
CTCTGGAGAAGGCAGTTCAGAATATCAAGTCAAGTCATGAAGATGTTCGCAATGTTGCCGAAAAGCTGGAAGACGTCCGA
CAGCAATTTGCGGGAGTAGACTCCAAGGGTAAGGAACTTTCTAAAAATGTGGAACATATGCTGGAAATAGTGACAACTGT
GGAAGAAATAGCGGAACAGACCAATCTACTGGCTCTCAATGCTTCCATAGAAGCGGCTAGGGCAGGAGAACACGGTCAAG
GTTTTGCTGTGGTAGCCAACGAAGTCCGTAACCTGGCTGAAAACTCGGGGAAAGCTGTGGGAACTATCAGTGACAATTTG
AAAAGCTTTGTTTCAGAAGTTGATAATCTGGTCAATGATATCACCAATCAATTTTCTCGGCTTGAGGAAAGTACCACAAC
TCTTCACAGTACTGCCGAGGAAACCGGACATGCCACAAATCAGATCAATCAGGTGGCTGAAAAAATCGCCGATATGGTGG
ACAAGCTTTCTAAGGAAACGGAGAACATGAACCAGGTCTTTGAAAGTATTAACTCCCTAGCGGCCATAGCCGAAGAAAAC
AGTGCCGCTTCAGAAGAGATGAGTTCTAATGTCAGTGAGTACTCTGAAAAAATCAAAGAAATGTCCGAATACACCGAGCA
GTTAAAAGTGTTGACAAGTGAGCTTCAAGGCGAACTAAAACGACACAAGGTTTAA

Upstream 100 bases:

>100_bases
ATTTTGTGCTAAATTGTAGAAATAAATAGAAGCTGGTAGATGAGATAAGAAATCATTACTAATATTTTTTATTTGAATTA
GAAGGGAGTGACAGCTTGCG

Downstream 100 bases:

>100_bases
TTAGAAATGAAAGTATAGTTAGAGATGAAGATATAGTTAGAAATGAAGATTTAATCAGAGATGAAGGTATATTAGAGATG
TAGTTTGGTGGCATGACTCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 604; Mature: 604

Protein sequence:

>604_residues
MKGTVVLAWINSLKDLYGEDQVTQVLSELGWEGDEIITPTMNVSDRDARGLIEKMAEKQGSSSSHVFRKLGRKNIWSFAE
LFPSYFDQSTAKEFLMMMDEVHRQLTKMISGATPPGLVAEELSPNTIKIKYVSNRGLFDYFLGLLEGVGDYFDEEINFEE
LDRGEDSNGEQYLDVKITTEQATAGIKEFPLSRFLSLGIIRGVPGKIALSSSVVITIIAAALNGFQLDTNLAVILVASFA
VIYGSAKIALAPLDVVRNELNKLKELDFSQALRVSSGDYIETLQNDLFESKTNIKKGLLFLKGGTDDLYKFVERYGNVSD
NMKELSGDISQMVQEVSQGAIQQAEETEGSVNSLQSNVETIQSIANEELEDKEALEKAVQNIKSSHEDVRNVAEKLEDVR
QQFAGVDSKGKELSKNVEHMLEIVTTVEEIAEQTNLLALNASIEAARAGEHGQGFAVVANEVRNLAENSGKAVGTISDNL
KSFVSEVDNLVNDITNQFSRLEESTTTLHSTAEETGHATNQINQVAEKIADMVDKLSKETENMNQVFESINSLAAIAEEN
SAASEEMSSNVSEYSEKIKEMSEYTEQLKVLTSELQGELKRHKV

Sequences:

>Translated_604_residues
MKGTVVLAWINSLKDLYGEDQVTQVLSELGWEGDEIITPTMNVSDRDARGLIEKMAEKQGSSSSHVFRKLGRKNIWSFAE
LFPSYFDQSTAKEFLMMMDEVHRQLTKMISGATPPGLVAEELSPNTIKIKYVSNRGLFDYFLGLLEGVGDYFDEEINFEE
LDRGEDSNGEQYLDVKITTEQATAGIKEFPLSRFLSLGIIRGVPGKIALSSSVVITIIAAALNGFQLDTNLAVILVASFA
VIYGSAKIALAPLDVVRNELNKLKELDFSQALRVSSGDYIETLQNDLFESKTNIKKGLLFLKGGTDDLYKFVERYGNVSD
NMKELSGDISQMVQEVSQGAIQQAEETEGSVNSLQSNVETIQSIANEELEDKEALEKAVQNIKSSHEDVRNVAEKLEDVR
QQFAGVDSKGKELSKNVEHMLEIVTTVEEIAEQTNLLALNASIEAARAGEHGQGFAVVANEVRNLAENSGKAVGTISDNL
KSFVSEVDNLVNDITNQFSRLEESTTTLHSTAEETGHATNQINQVAEKIADMVDKLSKETENMNQVFESINSLAAIAEEN
SAASEEMSSNVSEYSEKIKEMSEYTEQLKVLTSELQGELKRHKV
>Mature_604_residues
MKGTVVLAWINSLKDLYGEDQVTQVLSELGWEGDEIITPTMNVSDRDARGLIEKMAEKQGSSSSHVFRKLGRKNIWSFAE
LFPSYFDQSTAKEFLMMMDEVHRQLTKMISGATPPGLVAEELSPNTIKIKYVSNRGLFDYFLGLLEGVGDYFDEEINFEE
LDRGEDSNGEQYLDVKITTEQATAGIKEFPLSRFLSLGIIRGVPGKIALSSSVVITIIAAALNGFQLDTNLAVILVASFA
VIYGSAKIALAPLDVVRNELNKLKELDFSQALRVSSGDYIETLQNDLFESKTNIKKGLLFLKGGTDDLYKFVERYGNVSD
NMKELSGDISQMVQEVSQGAIQQAEETEGSVNSLQSNVETIQSIANEELEDKEALEKAVQNIKSSHEDVRNVAEKLEDVR
QQFAGVDSKGKELSKNVEHMLEIVTTVEEIAEQTNLLALNASIEAARAGEHGQGFAVVANEVRNLAENSGKAVGTISDNL
KSFVSEVDNLVNDITNQFSRLEESTTTLHSTAEETGHATNQINQVAEKIADMVDKLSKETENMNQVFESINSLAAIAEEN
SAASEEMSSNVSEYSEKIKEMSEYTEQLKVLTSELQGELKRHKV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=326, Percent_Identity=25.4601226993865, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788195, Length=233, Percent_Identity=28.755364806867, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788194, Length=193, Percent_Identity=31.6062176165803, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787690, Length=279, Percent_Identity=27.9569892473118, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789453, Length=351, Percent_Identity=24.2165242165242, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 66652; Mature: 66652

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTVVLAWINSLKDLYGEDQVTQVLSELGWEGDEIITPTMNVSDRDARGLIEKMAEKQG
CCCCEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCC
SSSSHVFRKLGRKNIWSFAELFPSYFDQSTAKEFLMMMDEVHRQLTKMISGATPPGLVAE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ELSPNTIKIKYVSNRGLFDYFLGLLEGVGDYFDEEINFEELDRGEDSNGEQYLDVKITTE
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEEEHH
QATAGIKEFPLSRFLSLGIIRGVPGKIALSSSVVITIIAAALNGFQLDTNLAVILVASFA
HHHCCHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCEECCHHHHHHHHHHH
VIYGSAKIALAPLDVVRNELNKLKELDFSQALRVSSGDYIETLQNDLFESKTNIKKGLLF
HHHCCCHHEEHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEE
LKGGTDDLYKFVERYGNVSDNMKELSGDISQMVQEVSQGAIQQAEETEGSVNSLQSNVET
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IQSIANEELEDKEALEKAVQNIKSSHEDVRNVAEKLEDVRQQFAGVDSKGKELSKNVEHM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LEIVTTVEEIAEQTNLLALNASIEAARAGEHGQGFAVVANEVRNLAENSGKAVGTISDNL
HHHHHHHHHHHHHHCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHH
KSFVSEVDNLVNDITNQFSRLEESTTTLHSTAEETGHATNQINQVAEKIADMVDKLSKET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ENMNQVFESINSLAAIAEENSAASEEMSSNVSEYSEKIKEMSEYTEQLKVLTSELQGELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHKV
HCCC
>Mature Secondary Structure
MKGTVVLAWINSLKDLYGEDQVTQVLSELGWEGDEIITPTMNVSDRDARGLIEKMAEKQG
CCCCEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHHHCC
SSSSHVFRKLGRKNIWSFAELFPSYFDQSTAKEFLMMMDEVHRQLTKMISGATPPGLVAE
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
ELSPNTIKIKYVSNRGLFDYFLGLLEGVGDYFDEEINFEELDRGEDSNGEQYLDVKITTE
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEEEHH
QATAGIKEFPLSRFLSLGIIRGVPGKIALSSSVVITIIAAALNGFQLDTNLAVILVASFA
HHHCCHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCEECCHHHHHHHHHHH
VIYGSAKIALAPLDVVRNELNKLKELDFSQALRVSSGDYIETLQNDLFESKTNIKKGLLF
HHHCCCHHEEHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEEE
LKGGTDDLYKFVERYGNVSDNMKELSGDISQMVQEVSQGAIQQAEETEGSVNSLQSNVET
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
IQSIANEELEDKEALEKAVQNIKSSHEDVRNVAEKLEDVRQQFAGVDSKGKELSKNVEHM
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
LEIVTTVEEIAEQTNLLALNASIEAARAGEHGQGFAVVANEVRNLAENSGKAVGTISDNL
HHHHHHHHHHHHHHCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHH
KSFVSEVDNLVNDITNQFSRLEESTTTLHSTAEETGHATNQINQVAEKIADMVDKLSKET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ENMNQVFESINSLAAIAEENSAASEEMSSNVSEYSEKIKEMSEYTEQLKVLTSELQGELK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHKV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]