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The map label for this gene is atoD [H]

Identifier: 188586857

GI number: 188586857

Start: 2385400

End: 2386056

Strand: Reverse

Name: atoD [H]

Synonym: Nther_2248

Alternate gene names: 188586857

Gene position: 2386056-2385400 (Counterclockwise)

Preceding gene: 188586858

Following gene: 188586856

Centisome position: 75.38

GC content: 35.62

Gene sequence:

>657_bases
ATGAAACAAATTTTAAGTGCTAAAGAGAGTGTTGAAAAGATATTTGATGGTATGACAGTTATGATAGGAGGTTTTCTTGC
GACAGGTACTCCAGAAACATTAGTCGATGCACTAGAGGATAAAGGTGTTAAGGATTTAACATTAATTGCAAACGATACCA
GTTATCCAGAGAAAGGGATTGGGCGTTTAGTTGTAAATGATCAATTTTCAAAAGTTTTCGTTTCCCACATTGGTACAAAC
AAATATACAGGAGAAAAAATGCATAACGATGAACTGGATGTAAACCTAGTACCTCAAGGAACTTTGGCAGAACAAATCAG
AGCAGGTGGAGCAGGTTTAGGAGGAATATTAACTCCTACAGGTATCGGTACTGTAGCAGAAGAAGGAAAACAAAAAATAA
AAATAAATAGAAAAGACTACATTTTAGCCGAATCTTTAACAGCAGATGTAGCGTTAATTAAAGCTGAACAAGCTGATGAA
TTTGGTAATTTAAGATATCGTCTTTCTGCTCGTAATTTCAACCCACTTATGGCAAAAGCAGCAAAAATAGTTATAGCAGA
AGTAGGAAGTATAGAACCGGCATCATCCTTTGACCCAGATGATATTCATACTCCTAGCGTATATGTAGATTATTTAGTAA
AAAGAGAGGAGGGGTAA

Upstream 100 bases:

>100_bases
TAATGGGTTATTGTCTAATGGCCCTCTTATTTTCAGGCGTAATTATAATCTTTGGATTACTCATATTTTAAGCAAAATCT
AATTAGGTGGTGAAGCTATT

Downstream 100 bases:

>100_bases
ATTATGGATAAGAATGAAAGACGAAATCTAATAGCAAGGCGAATTGCAAGAGAGTTTCAGACAGGAGAAGTTGTGAATCT
AGGCATTGGAATGCCCACAC

Product: butyryl-CoA:acetoacetate CoA-transferase alpha subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit alpha [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKQILSAKESVEKIFDGMTVMIGGFLATGTPETLVDALEDKGVKDLTLIANDTSYPEKGIGRLVVNDQFSKVFVSHIGTN
KYTGEKMHNDELDVNLVPQGTLAEQIRAGGAGLGGILTPTGIGTVAEEGKQKIKINRKDYILAESLTADVALIKAEQADE
FGNLRYRLSARNFNPLMAKAAKIVIAEVGSIEPASSFDPDDIHTPSVYVDYLVKREEG

Sequences:

>Translated_218_residues
MKQILSAKESVEKIFDGMTVMIGGFLATGTPETLVDALEDKGVKDLTLIANDTSYPEKGIGRLVVNDQFSKVFVSHIGTN
KYTGEKMHNDELDVNLVPQGTLAEQIRAGGAGLGGILTPTGIGTVAEEGKQKIKINRKDYILAESLTADVALIKAEQADE
FGNLRYRLSARNFNPLMAKAAKIVIAEVGSIEPASSFDPDDIHTPSVYVDYLVKREEG
>Mature_218_residues
MKQILSAKESVEKIFDGMTVMIGGFLATGTPETLVDALEDKGVKDLTLIANDTSYPEKGIGRLVVNDQFSKVFVSHIGTN
KYTGEKMHNDELDVNLVPQGTLAEQIRAGGAGLGGILTPTGIGTVAEEGKQKIKINRKDYILAESLTADVALIKAEQADE
FGNLRYRLSARNFNPLMAKAAKIVIAEVGSIEPASSFDPDDIHTPSVYVDYLVKREEG

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=227, Percent_Identity=42.7312775330396, Blast_Score=177, Evalue=7e-45,
Organism=Homo sapiens, GI11545841, Length=224, Percent_Identity=40.1785714285714, Blast_Score=161, Evalue=5e-40,
Organism=Escherichia coli, GI1788551, Length=215, Percent_Identity=52.093023255814, Blast_Score=234, Evalue=3e-63,
Organism=Escherichia coli, GI1787985, Length=239, Percent_Identity=24.6861924686192, Blast_Score=60, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17531517, Length=228, Percent_Identity=37.719298245614, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21358325, Length=227, Percent_Identity=40.9691629955947, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24655794, Length=227, Percent_Identity=40.9691629955947, Blast_Score=177, Evalue=7e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23542; Mature: 23542

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQILSAKESVEKIFDGMTVMIGGFLATGTPETLVDALEDKGVKDLTLIANDTSYPEKGI
CCHHHHHHHHHHHHHCCHHEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GRLVVNDQFSKVFVSHIGTNKYTGEKMHNDELDVNLVPQGTLAEQIRAGGAGLGGILTPT
CEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCC
GIGTVAEEGKQKIKINRKDYILAESLTADVALIKAEQADEFGNLRYRLSARNFNPLMAKA
CCCHHHHCCCCEEEECCCCEEEEHHHHHCEEEEEHHCCCCCCCEEEEEECCCCCHHHHHH
AKIVIAEVGSIEPASSFDPDDIHTPSVYVDYLVKREEG
HHHHEECCCCCCCCCCCCCCCCCCCHHHEEHHEECCCC
>Mature Secondary Structure
MKQILSAKESVEKIFDGMTVMIGGFLATGTPETLVDALEDKGVKDLTLIANDTSYPEKGI
CCHHHHHHHHHHHHHCCHHEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
GRLVVNDQFSKVFVSHIGTNKYTGEKMHNDELDVNLVPQGTLAEQIRAGGAGLGGILTPT
CEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHCCCCCCCCCCCCC
GIGTVAEEGKQKIKINRKDYILAESLTADVALIKAEQADEFGNLRYRLSARNFNPLMAKA
CCCHHHHCCCCEEEECCCCEEEEHHHHHCEEEEEHHCCCCCCCEEEEEECCCCCHHHHHH
AKIVIAEVGSIEPASSFDPDDIHTPSVYVDYLVKREEG
HHHHEECCCCCCCCCCCCCCCCCCCHHHEEHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]