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The map label for this gene is exuT [H]

Identifier: 188586855

GI number: 188586855

Start: 2383173

End: 2384456

Strand: Reverse

Name: exuT [H]

Synonym: Nther_2246

Alternate gene names: 188586855

Gene position: 2384456-2383173 (Counterclockwise)

Preceding gene: 188586856

Following gene: 188586854

Centisome position: 75.33

GC content: 41.2

Gene sequence:

>1284_bases
ATGCAACAACGGACAAAAATCTTTATATTAATGGTAATCTCCATGGTCTTAGGTTACTTGCCCTGGTATAACTTTTCAGC
AGTAATGAACTATATCGCTAAAGACTTCAATTTGTCATCAGACCAAACAGGAATGATCTTATCGGCTTTTCAAATGGGAT
ATGTCATTGTAGTTATTCTATCAGGATGGATTGCTGACAAAGTTGGTGACAAGAAAGTGGTTGCTTGGGCTACATTGAGT
ACAGCAGTTTTTTCTACGGCTTTTACATTTTTCAGCAGTGGTTTCTGGAGTATTCTCGTTTTAAGACTGTTAACTGGACT
CTCAGCCGGGGCAATATATGTTCCGGGAATGGCCCTTTTATCTAAATGGTTTCCCCCTAAAGAACGAGGGAAAGTTATTG
GCGGCTATACAGGGGCTATGACTTTAGCTTATGCCGGAGGGTACTTTATTGCAGGTCCTTTAGCATCAAATTTTGGCTGG
CAAGTCGGTATCTTATTTACTTCCCTTCCTGCTTTTATAGCAGCTTATATAGTTTTCTTTATGGTCCATGAGCCGGAAGA
ATCTACATACGAAGAATCAACAAAGCAGGATGCAGAGGAATCCGAGTCAAGTTATAGTAATACCGATGTCAAACCGGCAC
CCGAAGGTGGTTATGTAGGACCTTCTGTTATAACTGCAGGGTATATGGGGCATATGTGGGAACTGTATGCCTTCTGGGGT
TGGATTGGTCCATTCATGACAGCTTCTGCATTTAAAGTGGGTTATAGCAGTGCAGAGGCCGTTTCCCTGGGTAACTTTTT
AGCAGCTTTGATTATAGTGAGTGGAGCCCCAGCTGTGTATGTCATGGGGAAAATAGCTGACAAATGGGGAAGAAGTAAGA
CCATATTCATGTGTTCGATATTCAGCCTAGTTGCCCAATTGTTTTTAGGATTTTTACACGGACATTCCCTTGTCTTTGTA
ACACTTGTTGGTTTTTGGATAGGTTTTTGGGTAGTAGCTGATTCAGGAATATACAAGGCAGGTCTAACAGAGATGGTCAA
CTTCAGATTGAGATCAACCATGTTGGGAATTCAATCCGCTGCCGGCTATTTGATGACTGTGGTTTCACCCTATGTATTTG
GTGTAGTTCTGGATTTACAAAACAATGGGGCCGATCCCATGCATGCGGAAAACTGGAGTTTACCATTTATAATTTTAGGA
TTAGGTGCAATTTTAGCGCCCATATCAGCAATTATTATTAGAAAAACCCGACAAGGCAGTTTGATGGTCAATGGTAAGTA
TTAA

Upstream 100 bases:

>100_bases
AGGGAGGAATTTTTATAATCTCAGAGAATATTGATGAGTAACTGGTATGACCAGCAGACATCATACAATAATACAACCTA
AATTCAAAGGGGAGTTATTT

Downstream 100 bases:

>100_bases
TTTAACATAGATAACAAAAATTTATGGAGGTGTTTTCTAAGATGTCGAGTCAAAATTTTGAGACAAGGATTTTACATGCC
GATGAAGGTCACAAGAATGA

Product: major facilitator superfamily MFS_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MQQRTKIFILMVISMVLGYLPWYNFSAVMNYIAKDFNLSSDQTGMILSAFQMGYVIVVILSGWIADKVGDKKVVAWATLS
TAVFSTAFTFFSSGFWSILVLRLLTGLSAGAIYVPGMALLSKWFPPKERGKVIGGYTGAMTLAYAGGYFIAGPLASNFGW
QVGILFTSLPAFIAAYIVFFMVHEPEESTYEESTKQDAEESESSYSNTDVKPAPEGGYVGPSVITAGYMGHMWELYAFWG
WIGPFMTASAFKVGYSSAEAVSLGNFLAALIIVSGAPAVYVMGKIADKWGRSKTIFMCSIFSLVAQLFLGFLHGHSLVFV
TLVGFWIGFWVVADSGIYKAGLTEMVNFRLRSTMLGIQSAAGYLMTVVSPYVFGVVLDLQNNGADPMHAENWSLPFIILG
LGAILAPISAIIIRKTRQGSLMVNGKY

Sequences:

>Translated_427_residues
MQQRTKIFILMVISMVLGYLPWYNFSAVMNYIAKDFNLSSDQTGMILSAFQMGYVIVVILSGWIADKVGDKKVVAWATLS
TAVFSTAFTFFSSGFWSILVLRLLTGLSAGAIYVPGMALLSKWFPPKERGKVIGGYTGAMTLAYAGGYFIAGPLASNFGW
QVGILFTSLPAFIAAYIVFFMVHEPEESTYEESTKQDAEESESSYSNTDVKPAPEGGYVGPSVITAGYMGHMWELYAFWG
WIGPFMTASAFKVGYSSAEAVSLGNFLAALIIVSGAPAVYVMGKIADKWGRSKTIFMCSIFSLVAQLFLGFLHGHSLVFV
TLVGFWIGFWVVADSGIYKAGLTEMVNFRLRSTMLGIQSAAGYLMTVVSPYVFGVVLDLQNNGADPMHAENWSLPFIILG
LGAILAPISAIIIRKTRQGSLMVNGKY
>Mature_427_residues
MQQRTKIFILMVISMVLGYLPWYNFSAVMNYIAKDFNLSSDQTGMILSAFQMGYVIVVILSGWIADKVGDKKVVAWATLS
TAVFSTAFTFFSSGFWSILVLRLLTGLSAGAIYVPGMALLSKWFPPKERGKVIGGYTGAMTLAYAGGYFIAGPLASNFGW
QVGILFTSLPAFIAAYIVFFMVHEPEESTYEESTKQDAEESESSYSNTDVKPAPEGGYVGPSVITAGYMGHMWELYAFWG
WIGPFMTASAFKVGYSSAEAVSLGNFLAALIIVSGAPAVYVMGKIADKWGRSKTIFMCSIFSLVAQLFLGFLHGHSLVFV
TLVGFWIGFWVVADSGIYKAGLTEMVNFRLRSTMLGIQSAAGYLMTVVSPYVFGVVLDLQNNGADPMHAENWSLPFIILG
LGAILAPISAIIIRKTRQGSLMVNGKY

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI1789152, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082320, Length=136, Percent_Identity=27.2058823529412, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789515, Length=232, Percent_Identity=24.5689655172414, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=290, Percent_Identity=23.448275862069, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24583789, Length=213, Percent_Identity=27.2300469483568, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28573299, Length=427, Percent_Identity=24.1217798594848, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46507; Mature: 46507

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRTKIFILMVISMVLGYLPWYNFSAVMNYIAKDFNLSSDQTGMILSAFQMGYVIVVIL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
SGWIADKVGDKKVVAWATLSTAVFSTAFTFFSSGFWSILVLRLLTGLSAGAIYVPGMALL
HHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCHHHH
SKWFPPKERGKVIGGYTGAMTLAYAGGYFIAGPLASNFGWQVGILFTSLPAFIAAYIVFF
HHCCCCHHHCCEECCHHHHHHHHHCCCEEEECCHHCCCCCCHHHHHHHHHHHHHHHHHHH
MVHEPEESTYEESTKQDAEESESSYSNTDVKPAPEGGYVGPSVITAGYMGHMWELYAFWG
HEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
WIGPFMTASAFKVGYSSAEAVSLGNFLAALIIVSGAPAVYVMGKIADKWGRSKTIFMCSI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCEEHHHHH
FSLVAQLFLGFLHGHSLVFVTLVGFWIGFWVVADSGIYKAGLTEMVNFRLRSTMLGIQSA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGYLMTVVSPYVFGVVLDLQNNGADPMHAENWSLPFIILGLGAILAPISAIIIRKTRQGS
HHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCC
LMVNGKY
EEEECCC
>Mature Secondary Structure
MQQRTKIFILMVISMVLGYLPWYNFSAVMNYIAKDFNLSSDQTGMILSAFQMGYVIVVIL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
SGWIADKVGDKKVVAWATLSTAVFSTAFTFFSSGFWSILVLRLLTGLSAGAIYVPGMALL
HHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEECCCHHHH
SKWFPPKERGKVIGGYTGAMTLAYAGGYFIAGPLASNFGWQVGILFTSLPAFIAAYIVFF
HHCCCCHHHCCEECCHHHHHHHHHCCCEEEECCHHCCCCCCHHHHHHHHHHHHHHHHHHH
MVHEPEESTYEESTKQDAEESESSYSNTDVKPAPEGGYVGPSVITAGYMGHMWELYAFWG
HEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
WIGPFMTASAFKVGYSSAEAVSLGNFLAALIIVSGAPAVYVMGKIADKWGRSKTIFMCSI
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHCCCCCEEHHHHH
FSLVAQLFLGFLHGHSLVFVTLVGFWIGFWVVADSGIYKAGLTEMVNFRLRSTMLGIQSA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGYLMTVVSPYVFGVVLDLQNNGADPMHAENWSLPFIILGLGAILAPISAIIIRKTRQGS
HHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCC
LMVNGKY
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]