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The map label for this gene is yegE [C]

Identifier: 188586720

GI number: 188586720

Start: 2226197

End: 2228641

Strand: Reverse

Name: yegE [C]

Synonym: Nther_2110

Alternate gene names: 188586720

Gene position: 2228641-2226197 (Counterclockwise)

Preceding gene: 188586722

Following gene: 188586719

Centisome position: 70.4

GC content: 34.97

Gene sequence:

>2445_bases
ATGTCCGATTATAAAATAGATAAGTCGCTTGAAGTAGGAGAATTAAAAATAGAAGAAATCATTGATATAGAAGAAATCAA
ACCCATAATGGATGAGTTTTATCAAAACACGAAAATTAGCGCAGCTTTAATGGACCTGGAGGGGAACATTTTAGTTTCTA
CATATTGGCAAGATATTTGTGAAAATTATCATAGAAAACATTCCGAAACCCGGAAAAATTGCATACAAAGCGATCTTAAC
TTTTCCAAGGGTGCTGAGAGTGGCAGCTATGTAGCTTATAAATGTAAAAATAATTTGCGCGATGTGGCAATACCTATTCA
TATAGAAGGAGAACAAATAGGTATTGTATTTGTGGGTCAATTTTTTTATGAAGATGATGAGATAGATTTAGTATATTTTA
CAAATCAAGCTGAAAAGTATGGCTTTGATAAAGGCAAGTACTTGCAAGCTCTTAAAAATGTTCCTAAAGTTAATAAGCTG
AAATTACAATCAATTATAAACTTTTATACCAAACTAGCCCATTTGATTTCTACTCTGGGTCATAAGAATGTCAAGCTTCA
AAGGAATCTAAAAGCTCAGAACAATGTAAAACAAGCTCTTAGAAAAAGTGAGGAAAATTTAGCAGCAACCTTACATTCCA
TTGGAGATGGTGTAATTGTTACAGATAAACAGGGTTTGATAACCAGGATGAATCCAGTGGCAGAACAGTTGACGGGTTGG
CCTATGAAACAGGCTAAGGATAAACAGTTAGAAATTGTGTTTTACGTTGTGGACCAGGCCGGAGAGAAAATTTTGGATCC
GGTTAAGCAAGTTATTCTCAATGGTGAAATTGTTGACTTGGGGAATAACTATGCAACTCTGATTTCTCGCCATGGAAATA
GAAGACAGATTTCAGAAAGTGCTGCTCCAATTTATAATCAAGAAGGGGAAATTATGGGAGTAGTAATTGTTTTTTCAGAT
GTTACAGAACAATACAAGATTCGCGAAGACCTAAAAAAATCTGAACAGCTATTGCAATCGACCCTTGATTCACTAAGTGC
CCACATTTGTGTTCTTGATGAAGAAGGCGTTATACGTATTGTCAATAAATCATGGATGGATTTTGGTCGTGGAAATAATG
CCCCTCTAGATTTGATAAGTCCAGGCGTCAATTACCTAGAAGTATGTGAAAGAGCTGAAGGTGATGGTGCCGAATTTGCG
TGGGAATTTCTAAATGGTATTTACGACGTCAAAAAAGGTGAATTAAATTATTTTGAGTTGGAATATCCTTGTCATTCTCC
CACAAAAAACAGATGGTTTATTGGCCGGGTAACTCCTCATCAAGGATACTTTAATAACTCAAGTGATACTGGGATTGTAA
TTGCCCATGAAGATATAACTGCAAGAAAGCAAGCAGAAGAGAGAATAAAGTATTTAAGTTTTCATGATAGCCTGACAAGT
CTTTATAATAGGGCTTATTTGGAAGAGCAAATCAAGAAGTTAGATGTTGAAGGACAGTTACCGATTAGTTTGATACTGGC
AGATTTAAATGGACTAAAATTGGTGAATGACAGTTACGGACATGAATGTGGGGATCAATTACTTCTTCAAACTTCAAAAA
TATTAACGCAATCCTGCAGAAAAGATGATATTATTGCCAGATGGGGTGGAGATGAATTTGTCATTTTACTGACAAAGACA
AATAAGGAAGATGCAGAGAAAATATGTAATCGGATAAAAAATCTCTGTATAACAACTAAACAAGAAGAAATCCCAGTTTC
TATAACCTTGGGAGTGTCTACCAAAGAAAATAGTGAAGAGGATATATATAATGTATTGATTGCTGCAGAAGAAGAAATGT
ATAAGAATAAATTAGTTGAAAGCCGAAGTGCCAAGAGCAATATTTTAAAGGCTTTACTAAATACTCTGGGGGCTAAAAGT
TTTGAAACGGAAGAACACGCTAGACGAATGCAAGAAATGGCATATAAAATAGGTGTTAAAATAGAATTAACTGAATCTGA
ACTGGATCGCCTGGTGTTACTAGTTTCAATGCATGATATTGGAAAAATTACCATACCCGAAGAAATTTTAACTAAACCAG
AAAACTTGACTAAAAATGAATGGGAATTAGTAAAGAAACATCCAGAAACAGGGTATTGGATTGCTCGGTCAACTGAAGAG
TTTTCTCATATAGCAGAAGATATTTTGTATCATCATGAAAAGTGGGACGGAACGGGCTATCCTCAAGGATTAGAAGGTGA
AAAAATTCCTTTATTAGCAAGGATAACTGCTATAGTTGATTCATATGATGTAATGATCTATGGCAGACCCTATAAGGAAG
CCGTTCCACCTGAACAAGCATTAAGGGAAATTAAAGACAATGCAAGAACTCAATTTGATCCAGAATTAGTTGATATTTTT
ATGGGTGTTTTAGAAGAAGACTACGGTATTTTTGAAGTTCAGTAA

Upstream 100 bases:

>100_bases
TGACTACGCAACAGCTATTGCTGAAGCTTGTATTAATACTAATTATAGTGAACTTTTTGTATTTGTACTGGTACGACACC
AGTGAAAAGGAGTGGACAAT

Downstream 100 bases:

>100_bases
TTTTTGGAGGGATATAATGCTTTTAAAAGACCTTCGAACCGAAGTGATAAAGTGTTGTCGTAAATTAGCAGACAATCAGC
TTACCCCCGGGACCACTGGG

Product: diguanylate cyclase and metal dependent phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 814; Mature: 813

Protein sequence:

>814_residues
MSDYKIDKSLEVGELKIEEIIDIEEIKPIMDEFYQNTKISAALMDLEGNILVSTYWQDICENYHRKHSETRKNCIQSDLN
FSKGAESGSYVAYKCKNNLRDVAIPIHIEGEQIGIVFVGQFFYEDDEIDLVYFTNQAEKYGFDKGKYLQALKNVPKVNKL
KLQSIINFYTKLAHLISTLGHKNVKLQRNLKAQNNVKQALRKSEENLAATLHSIGDGVIVTDKQGLITRMNPVAEQLTGW
PMKQAKDKQLEIVFYVVDQAGEKILDPVKQVILNGEIVDLGNNYATLISRHGNRRQISESAAPIYNQEGEIMGVVIVFSD
VTEQYKIREDLKKSEQLLQSTLDSLSAHICVLDEEGVIRIVNKSWMDFGRGNNAPLDLISPGVNYLEVCERAEGDGAEFA
WEFLNGIYDVKKGELNYFELEYPCHSPTKNRWFIGRVTPHQGYFNNSSDTGIVIAHEDITARKQAEERIKYLSFHDSLTS
LYNRAYLEEQIKKLDVEGQLPISLILADLNGLKLVNDSYGHECGDQLLLQTSKILTQSCRKDDIIARWGGDEFVILLTKT
NKEDAEKICNRIKNLCITTKQEEIPVSITLGVSTKENSEEDIYNVLIAAEEEMYKNKLVESRSAKSNILKALLNTLGAKS
FETEEHARRMQEMAYKIGVKIELTESELDRLVLLVSMHDIGKITIPEEILTKPENLTKNEWELVKKHPETGYWIARSTEE
FSHIAEDILYHHEKWDGTGYPQGLEGEKIPLLARITAIVDSYDVMIYGRPYKEAVPPEQALREIKDNARTQFDPELVDIF
MGVLEEDYGIFEVQ

Sequences:

>Translated_814_residues
MSDYKIDKSLEVGELKIEEIIDIEEIKPIMDEFYQNTKISAALMDLEGNILVSTYWQDICENYHRKHSETRKNCIQSDLN
FSKGAESGSYVAYKCKNNLRDVAIPIHIEGEQIGIVFVGQFFYEDDEIDLVYFTNQAEKYGFDKGKYLQALKNVPKVNKL
KLQSIINFYTKLAHLISTLGHKNVKLQRNLKAQNNVKQALRKSEENLAATLHSIGDGVIVTDKQGLITRMNPVAEQLTGW
PMKQAKDKQLEIVFYVVDQAGEKILDPVKQVILNGEIVDLGNNYATLISRHGNRRQISESAAPIYNQEGEIMGVVIVFSD
VTEQYKIREDLKKSEQLLQSTLDSLSAHICVLDEEGVIRIVNKSWMDFGRGNNAPLDLISPGVNYLEVCERAEGDGAEFA
WEFLNGIYDVKKGELNYFELEYPCHSPTKNRWFIGRVTPHQGYFNNSSDTGIVIAHEDITARKQAEERIKYLSFHDSLTS
LYNRAYLEEQIKKLDVEGQLPISLILADLNGLKLVNDSYGHECGDQLLLQTSKILTQSCRKDDIIARWGGDEFVILLTKT
NKEDAEKICNRIKNLCITTKQEEIPVSITLGVSTKENSEEDIYNVLIAAEEEMYKNKLVESRSAKSNILKALLNTLGAKS
FETEEHARRMQEMAYKIGVKIELTESELDRLVLLVSMHDIGKITIPEEILTKPENLTKNEWELVKKHPETGYWIARSTEE
FSHIAEDILYHHEKWDGTGYPQGLEGEKIPLLARITAIVDSYDVMIYGRPYKEAVPPEQALREIKDNARTQFDPELVDIF
MGVLEEDYGIFEVQ
>Mature_813_residues
SDYKIDKSLEVGELKIEEIIDIEEIKPIMDEFYQNTKISAALMDLEGNILVSTYWQDICENYHRKHSETRKNCIQSDLNF
SKGAESGSYVAYKCKNNLRDVAIPIHIEGEQIGIVFVGQFFYEDDEIDLVYFTNQAEKYGFDKGKYLQALKNVPKVNKLK
LQSIINFYTKLAHLISTLGHKNVKLQRNLKAQNNVKQALRKSEENLAATLHSIGDGVIVTDKQGLITRMNPVAEQLTGWP
MKQAKDKQLEIVFYVVDQAGEKILDPVKQVILNGEIVDLGNNYATLISRHGNRRQISESAAPIYNQEGEIMGVVIVFSDV
TEQYKIREDLKKSEQLLQSTLDSLSAHICVLDEEGVIRIVNKSWMDFGRGNNAPLDLISPGVNYLEVCERAEGDGAEFAW
EFLNGIYDVKKGELNYFELEYPCHSPTKNRWFIGRVTPHQGYFNNSSDTGIVIAHEDITARKQAEERIKYLSFHDSLTSL
YNRAYLEEQIKKLDVEGQLPISLILADLNGLKLVNDSYGHECGDQLLLQTSKILTQSCRKDDIIARWGGDEFVILLTKTN
KEDAEKICNRIKNLCITTKQEEIPVSITLGVSTKENSEEDIYNVLIAAEEEMYKNKLVESRSAKSNILKALLNTLGAKSF
ETEEHARRMQEMAYKIGVKIELTESELDRLVLLVSMHDIGKITIPEEILTKPENLTKNEWELVKKHPETGYWIARSTEEF
SHIAEDILYHHEKWDGTGYPQGLEGEKIPLLARITAIVDSYDVMIYGRPYKEAVPPEQALREIKDNARTQFDPELVDIFM
GVLEEDYGIFEVQ

Specific function: Unknown

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=284, Percent_Identity=29.2253521126761, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87082007, Length=161, Percent_Identity=31.055900621118, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=31.0344827586207, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787541, Length=296, Percent_Identity=26.3513513513513, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI145693134, Length=150, Percent_Identity=30, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=32.9113924050633, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787816, Length=147, Percent_Identity=34.6938775510204, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=147, Percent_Identity=34.0136054421769, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786584, Length=166, Percent_Identity=28.3132530120482, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=151, Percent_Identity=27.8145695364238, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788085, Length=128, Percent_Identity=33.59375, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1788549, Length=186, Percent_Identity=27.9569892473118, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR003607 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 92835; Mature: 92703

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYKIDKSLEVGELKIEEIIDIEEIKPIMDEFYQNTKISAALMDLEGNILVSTYWQDIC
CCCCCCCCCCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHHHHHH
ENYHRKHSETRKNCIQSDLNFSKGAESGSYVAYKCKNNLRDVAIPIHIEGEQIGIVFVGQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCEEEEEEEEE
FFYEDDEIDLVYFTNQAEKYGFDKGKYLQALKNVPKVNKLKLQSIINFYTKLAHLISTLG
EEECCCCEEEEEEECCHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
HKNVKLQRNLKAQNNVKQALRKSEENLAATLHSIGDGVIVTDKQGLITRMNPVAEQLTGW
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHCCHHHHHHCCC
PMKQAKDKQLEIVFYVVDQAGEKILDPVKQVILNGEIVDLGNNYATLISRHGNRRQISES
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHCCCCHHHHHHC
AAPIYNQEGEIMGVVIVFSDVTEQYKIREDLKKSEQLLQSTLDSLSAHICVLDEEGVIRI
CCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEE
VNKSWMDFGRGNNAPLDLISPGVNYLEVCERAEGDGAEFAWEFLNGIYDVKKGELNYFEL
ECHHHHHCCCCCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
EYPCHSPTKNRWFIGRVTPHQGYFNNSSDTGIVIAHEDITARKQAEERIKYLSFHDSLTS
ECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
LYNRAYLEEQIKKLDVEGQLPISLILADLNGLKLVNDSYGHECGDQLLLQTSKILTQSCR
HHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
KDDIIARWGGDEFVILLTKTNKEDAEKICNRIKNLCITTKQEEIPVSITLGVSTKENSEE
CCCEEEEECCCEEEEEEEECCHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCHH
DIYNVLIAAEEEMYKNKLVESRSAKSNILKALLNTLGAKSFETEEHARRMQEMAYKIGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCE
IELTESELDRLVLLVSMHDIGKITIPEEILTKPENLTKNEWELVKKHPETGYWIARSTEE
EEECHHHHHHEEEEEECCCCCCEECCHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECHHH
FSHIAEDILYHHEKWDGTGYPQGLEGEKIPLLARITAIVDSYDVMIYGRPYKEAVPPEQA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHCCCHHHH
LREIKDNARTQFDPELVDIFMGVLEEDYGIFEVQ
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SDYKIDKSLEVGELKIEEIIDIEEIKPIMDEFYQNTKISAALMDLEGNILVSTYWQDIC
CCCCCCCCCCCCCEEHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEHHHHHHHH
ENYHRKHSETRKNCIQSDLNFSKGAESGSYVAYKCKNNLRDVAIPIHIEGEQIGIVFVGQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCEEEEEEEEE
FFYEDDEIDLVYFTNQAEKYGFDKGKYLQALKNVPKVNKLKLQSIINFYTKLAHLISTLG
EEECCCCEEEEEEECCHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
HKNVKLQRNLKAQNNVKQALRKSEENLAATLHSIGDGVIVTDKQGLITRMNPVAEQLTGW
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHCCHHHHHHCCC
PMKQAKDKQLEIVFYVVDQAGEKILDPVKQVILNGEIVDLGNNYATLISRHGNRRQISES
CCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHCCCCHHHHHHC
AAPIYNQEGEIMGVVIVFSDVTEQYKIREDLKKSEQLLQSTLDSLSAHICVLDEEGVIRI
CCCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEE
VNKSWMDFGRGNNAPLDLISPGVNYLEVCERAEGDGAEFAWEFLNGIYDVKKGELNYFEL
ECHHHHHCCCCCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCEEEE
EYPCHSPTKNRWFIGRVTPHQGYFNNSSDTGIVIAHEDITARKQAEERIKYLSFHDSLTS
ECCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
LYNRAYLEEQIKKLDVEGQLPISLILADLNGLKLVNDSYGHECGDQLLLQTSKILTQSCR
HHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCC
KDDIIARWGGDEFVILLTKTNKEDAEKICNRIKNLCITTKQEEIPVSITLGVSTKENSEE
CCCEEEEECCCEEEEEEEECCHHHHHHHHHHHHHHEEECCCCCCCEEEEEECCCCCCCHH
DIYNVLIAAEEEMYKNKLVESRSAKSNILKALLNTLGAKSFETEEHARRMQEMAYKIGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCE
IELTESELDRLVLLVSMHDIGKITIPEEILTKPENLTKNEWELVKKHPETGYWIARSTEE
EEECHHHHHHEEEEEECCCCCCEECCHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECHHH
FSHIAEDILYHHEKWDGTGYPQGLEGEKIPLLARITAIVDSYDVMIYGRPYKEAVPPEQA
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHCCCHHHH
LREIKDNARTQFDPELVDIFMGVLEEDYGIFEVQ
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]