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The map label for this gene is fucA [H]

Identifier: 188586719

GI number: 188586719

Start: 2225542

End: 2226180

Strand: Reverse

Name: fucA [H]

Synonym: Nther_2109

Alternate gene names: 188586719

Gene position: 2226180-2225542 (Counterclockwise)

Preceding gene: 188586720

Following gene: 188586718

Centisome position: 70.33

GC content: 41.63

Gene sequence:

>639_bases
ATGCTTTTAAAAGACCTTCGAACCGAAGTGATAAAGTGTTGTCGTAAATTAGCAGACAATCAGCTTACCCCCGGGACCAC
TGGGAATGTAAGTGCCCTGAATCGTGAGGAAGGCTTAATGGCGATTTCACCAAGTGGGCTGGAATATCATGACATGACAG
TGGAAGAAGTCGTGGTTATGGATTTAGATGGGAATGTGATAGAAGGGAAGGGAGCCCCTTCAAGTGAATGGCCGCTACAT
TTAAAATGTTATCAGCACAGACAGGATCTAGCAGGAGTAGTTCATACCCATTCTATATATTCGACTATTTTTTCTTGTTT
AAATCAGAGTATAGAACCGGTACATTACATGATAGCTTTTTCCGGTCTAAGAGTGCCTTGTGCTGAATATGCCAGACCAG
GTTCAGAAGAATTAGCTGTAAAAGCAGTGGAAGAATTAGAAAATTATAATGCCGTATTACTTGCCAATCACGGTTTACTG
ACGGCGGGTAAAAGTTTACGGGAGGCCTTTGTGACTGCCGAACAGGTGGAATTTGTGGCTGAAATTTACTATAAAACAAA
AGCTTTGGCTGAACCAGTTATTATATCAGACCAAGAAATGTCGGCAATTATAAACCAACTCGGTAACTATGGGCGCTAA

Upstream 100 bases:

>100_bases
GCAAGAACTCAATTTGATCCAGAATTAGTTGATATTTTTATGGGTGTTTTAGAAGAAGACTACGGTATTTTTGAAGTTCA
GTAATTTTTGGAGGGATATA

Downstream 100 bases:

>100_bases
TTGGAATATTTTTGAAGGTTTCTCTAAATATATATAGAAAATTAAGAATAGTGTCAAAAGAGGGGCGAATATCAATGGGG
AAATTAAATCTTCGTGCTCA

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MLLKDLRTEVIKCCRKLADNQLTPGTTGNVSALNREEGLMAISPSGLEYHDMTVEEVVVMDLDGNVIEGKGAPSSEWPLH
LKCYQHRQDLAGVVHTHSIYSTIFSCLNQSIEPVHYMIAFSGLRVPCAEYARPGSEELAVKAVEELENYNAVLLANHGLL
TAGKSLREAFVTAEQVEFVAEIYYKTKALAEPVIISDQEMSAIINQLGNYGR

Sequences:

>Translated_212_residues
MLLKDLRTEVIKCCRKLADNQLTPGTTGNVSALNREEGLMAISPSGLEYHDMTVEEVVVMDLDGNVIEGKGAPSSEWPLH
LKCYQHRQDLAGVVHTHSIYSTIFSCLNQSIEPVHYMIAFSGLRVPCAEYARPGSEELAVKAVEELENYNAVLLANHGLL
TAGKSLREAFVTAEQVEFVAEIYYKTKALAEPVIISDQEMSAIINQLGNYGR
>Mature_212_residues
MLLKDLRTEVIKCCRKLADNQLTPGTTGNVSALNREEGLMAISPSGLEYHDMTVEEVVVMDLDGNVIEGKGAPSSEWPLH
LKCYQHRQDLAGVVHTHSIYSTIFSCLNQSIEPVHYMIAFSGLRVPCAEYARPGSEELAVKAVEELENYNAVLLANHGLL
TAGKSLREAFVTAEQVEFVAEIYYKTKALAEPVIISDQEMSAIINQLGNYGR

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=208, Percent_Identity=38.9423076923077, Blast_Score=146, Evalue=9e-37,
Organism=Escherichia coli, GI1786247, Length=195, Percent_Identity=34.8717948717949, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790642, Length=200, Percent_Identity=32, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790008, Length=105, Percent_Identity=40, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789094, Length=186, Percent_Identity=30.1075268817204, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23384; Mature: 23384

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKDLRTEVIKCCRKLADNQLTPGTTGNVSALNREEGLMAISPSGLEYHDMTVEEVVVM
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCCHHHEEEE
DLDGNVIEGKGAPSSEWPLHLKCYQHRQDLAGVVHTHSIYSTIFSCLNQSIEPVHYMIAF
ECCCCEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SGLRVPCAEYARPGSEELAVKAVEELENYNAVLLANHGLLTAGKSLREAFVTAEQVEFVA
CCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
EIYYKTKALAEPVIISDQEMSAIINQLGNYGR
HHHHHHHHHCCCEEECCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLKDLRTEVIKCCRKLADNQLTPGTTGNVSALNREEGLMAISPSGLEYHDMTVEEVVVM
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEECCCCCCCCCCCHHHEEEE
DLDGNVIEGKGAPSSEWPLHLKCYQHRQDLAGVVHTHSIYSTIFSCLNQSIEPVHYMIAF
ECCCCEEECCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
SGLRVPCAEYARPGSEELAVKAVEELENYNAVLLANHGLLTAGKSLREAFVTAEQVEFVA
CCCCCCHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
EIYYKTKALAEPVIISDQEMSAIINQLGNYGR
HHHHHHHHHCCCEEECCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]