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The map label for this gene is aroA [H]

Identifier: 188586662

GI number: 188586662

Start: 2168409

End: 2169863

Strand: Direct

Name: aroA [H]

Synonym: Nther_2052

Alternate gene names: 188586662

Gene position: 2168409-2169863 (Clockwise)

Preceding gene: 188586661

Following gene: 188586679

Centisome position: 68.5

GC content: 36.43

Gene sequence:

>1455_bases
ATGGAAATTTTAATTAACAATAGTAATGCTAAAAACCACTTTCAAGATACAAAATCTTCAGAAAGTAAAGTTATGCAAGA
TAATGAACAAAAATTTAGGTCTCTTAAAGGAAGCTTACATGTCCCAGGTGATAAATCAATAACACATAGATCTTATATTT
TAGGGTCAGTTGTCCCAGGTGTTGTAAAAATTAAAGGAAGAGCTTTAGGGGAAGATTGTGAGGCTACTTTAGAATGTCTT
AAGGCTATGGGAGCTGAAGGTAGTTCTAATTCTGAGGATGAAGATTATGAGATTACTAGCCATTCTCTTTATGAGCCTTC
AGAAGTTTTAGATGCAGGAAATTCAGGCACAACCGCTCGTTTATTATTAGGATTGATTTCAGGATTAAATCTCTTTGCTT
GTATTACAGGAGATGATTCTTTAAAAAAAAGACCAATGGATCGCGTCATTTCACCTTTAGCTAAATTGGGCAAAGATATC
AGGGCTAGACAGAATAATAGTAAACTTCCTGCTGCCATAATACCTGTAGAGATGCAAAACCAAAGCACAACAGTTAAATC
TATCTCAAAATCTACGCCAACCATTAAAACACAAGTTTCAAGTGCACAGGTGAAATCAGCCCTATTATTGGCTTCTTTAA
AAACAGATGGAATAAATGTAATTGAATCACAACAAACTAGAGATCACACAGAACGTATGTTATCTTTTATGGGATTTTCA
GTTCTAGAAAATGTCATGCAAAACGAGCACGAACCGGAGTCGGACCAAAATGTTCATCAGATAACTTTACCCGGAGGGCA
ATTGAGCAAGCTCAAACCTAGAGATTATGTATTGGATATACCAGGAGATCTATCATCTGCAGCTTTTTTGATAACTGCAG
CTCTATTAGTGCCGGGAAGTCAGGTCAAATTGCTTAATTGTGGATTAAACCCAACAAGGACGGGATTTGTAAAAATACTA
CAGCAATTAGGTGCCAGGATTACAATTACTAATAATACTACCTTAGCTGCTGAACCAAGAGGTGATATTAATGTAGAATA
TAGCCCTTGTCTACAAGGATTTCAATTGGGAAAAAACCTGGTCCCTGATACAATAGACGAACTTCCATTACTAGCGGTGA
TTGCAGTTCTTTCCCATGGGACTACTAAAGTGTCAGGAGCAGAAGAATTACGATATAAAGAAAGTGATAGAATTTCCGCT
ATCACCCAAGAATTGACCAAACTTGGAGCAGATATAACAGAAACTCAAGATGGCTTTATTGTTAACGGACCCACACAACT
AACAGGTAATGTAGTGGATTCTCATGGAGACCATCGTATTGCTATGGCTTTAACAGTAGCTGCCTTAACCGCCCAAGGGA
AAACCATCATAAAAAATTCTGACTGTATTAATATATCTTATCCAGGTTTTATTCAAGATTTAACAAAACTAGGAGCTATA
ATAGAACAACATTAA

Upstream 100 bases:

>100_bases
TCAGAACAGAATATTAAACGTATTGAAATAAAAGAATACTTATCAACAGCTTCAAACACTAGACAAAAGCTAGAATCCAG
ATTTTGAAAGGGAGATTTCA

Downstream 100 bases:

>100_bases
ATCTTTACTCTTAATAGAAGATTTTATAATTAAAATTTCATCTTATATATCTTAAATTAAGTATATTAAATACAAAAAAA
GTGGAGACAATCTTTTAATA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MEILINNSNAKNHFQDTKSSESKVMQDNEQKFRSLKGSLHVPGDKSITHRSYILGSVVPGVVKIKGRALGEDCEATLECL
KAMGAEGSSNSEDEDYEITSHSLYEPSEVLDAGNSGTTARLLLGLISGLNLFACITGDDSLKKRPMDRVISPLAKLGKDI
RARQNNSKLPAAIIPVEMQNQSTTVKSISKSTPTIKTQVSSAQVKSALLLASLKTDGINVIESQQTRDHTERMLSFMGFS
VLENVMQNEHEPESDQNVHQITLPGGQLSKLKPRDYVLDIPGDLSSAAFLITAALLVPGSQVKLLNCGLNPTRTGFVKIL
QQLGARITITNNTTLAAEPRGDINVEYSPCLQGFQLGKNLVPDTIDELPLLAVIAVLSHGTTKVSGAEELRYKESDRISA
ITQELTKLGADITETQDGFIVNGPTQLTGNVVDSHGDHRIAMALTVAALTAQGKTIIKNSDCINISYPGFIQDLTKLGAI
IEQH

Sequences:

>Translated_484_residues
MEILINNSNAKNHFQDTKSSESKVMQDNEQKFRSLKGSLHVPGDKSITHRSYILGSVVPGVVKIKGRALGEDCEATLECL
KAMGAEGSSNSEDEDYEITSHSLYEPSEVLDAGNSGTTARLLLGLISGLNLFACITGDDSLKKRPMDRVISPLAKLGKDI
RARQNNSKLPAAIIPVEMQNQSTTVKSISKSTPTIKTQVSSAQVKSALLLASLKTDGINVIESQQTRDHTERMLSFMGFS
VLENVMQNEHEPESDQNVHQITLPGGQLSKLKPRDYVLDIPGDLSSAAFLITAALLVPGSQVKLLNCGLNPTRTGFVKIL
QQLGARITITNNTTLAAEPRGDINVEYSPCLQGFQLGKNLVPDTIDELPLLAVIAVLSHGTTKVSGAEELRYKESDRISA
ITQELTKLGADITETQDGFIVNGPTQLTGNVVDSHGDHRIAMALTVAALTAQGKTIIKNSDCINISYPGFIQDLTKLGAI
IEQH
>Mature_484_residues
MEILINNSNAKNHFQDTKSSESKVMQDNEQKFRSLKGSLHVPGDKSITHRSYILGSVVPGVVKIKGRALGEDCEATLECL
KAMGAEGSSNSEDEDYEITSHSLYEPSEVLDAGNSGTTARLLLGLISGLNLFACITGDDSLKKRPMDRVISPLAKLGKDI
RARQNNSKLPAAIIPVEMQNQSTTVKSISKSTPTIKTQVSSAQVKSALLLASLKTDGINVIESQQTRDHTERMLSFMGFS
VLENVMQNEHEPESDQNVHQITLPGGQLSKLKPRDYVLDIPGDLSSAAFLITAALLVPGSQVKLLNCGLNPTRTGFVKIL
QQLGARITITNNTTLAAEPRGDINVEYSPCLQGFQLGKNLVPDTIDELPLLAVIAVLSHGTTKVSGAEELRYKESDRISA
ITQELTKLGADITETQDGFIVNGPTQLTGNVVDSHGDHRIAMALTVAALTAQGKTIIKNSDCINISYPGFIQDLTKLGAI
IEQH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=456, Percent_Identity=25, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=488, Percent_Identity=25.6147540983607, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 52205; Mature: 52205

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILINNSNAKNHFQDTKSSESKVMQDNEQKFRSLKGSLHVPGDKSITHRSYILGSVVPG
CEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCC
VVKIKGRALGEDCEATLECLKAMGAEGSSNSEDEDYEITSHSLYEPSEVLDAGNSGTTAR
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCHHHH
LLLGLISGLNLFACITGDDSLKKRPMDRVISPLAKLGKDIRARQNNSKLPAAIIPVEMQN
HHHHHHCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
QSTTVKSISKSTPTIKTQVSSAQVKSALLLASLKTDGINVIESQQTRDHTERMLSFMGFS
CCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHH
VLENVMQNEHEPESDQNVHQITLPGGQLSKLKPRDYVLDIPGDLSSAAFLITAALLVPGS
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
QVKLLNCGLNPTRTGFVKILQQLGARITITNNTTLAAEPRGDINVEYSPCLQGFQLGKNL
CEEEEECCCCCCHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCCCHHHHHHHHHHCCCC
VPDTIDELPLLAVIAVLSHGTTKVSGAEELRYKESDRISAITQELTKLGADITETQDGFI
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEE
VNGPTQLTGNVVDSHGDHRIAMALTVAALTAQGKTIIKNSDCINISYPGFIQDLTKLGAI
ECCCCCCCCCHHCCCCCCEEHHHHHHHHHHHCCCEEEECCCEEEECCCHHHHHHHHHHHH
IEQH
HHCC
>Mature Secondary Structure
MEILINNSNAKNHFQDTKSSESKVMQDNEQKFRSLKGSLHVPGDKSITHRSYILGSVVPG
CEEEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCC
VVKIKGRALGEDCEATLECLKAMGAEGSSNSEDEDYEITSHSLYEPSEVLDAGNSGTTAR
EEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHCCCCCCHHHH
LLLGLISGLNLFACITGDDSLKKRPMDRVISPLAKLGKDIRARQNNSKLPAAIIPVEMQN
HHHHHHCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
QSTTVKSISKSTPTIKTQVSSAQVKSALLLASLKTDGINVIESQQTRDHTERMLSFMGFS
CCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHHHHH
VLENVMQNEHEPESDQNVHQITLPGGQLSKLKPRDYVLDIPGDLSSAAFLITAALLVPGS
HHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
QVKLLNCGLNPTRTGFVKILQQLGARITITNNTTLAAEPRGDINVEYSPCLQGFQLGKNL
CEEEEECCCCCCHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCCCHHHHHHHHHHCCCC
VPDTIDELPLLAVIAVLSHGTTKVSGAEELRYKESDRISAITQELTKLGADITETQDGFI
CCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEE
VNGPTQLTGNVVDSHGDHRIAMALTVAALTAQGKTIIKNSDCINISYPGFIQDLTKLGAI
ECCCCCCCCCHHCCCCCCEEHHHHHHHHHHHCCCEEEECCCEEEECCCHHHHHHHHHHHH
IEQH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA