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The map label for this gene is hisK [H]

Identifier: 188586605

GI number: 188586605

Start: 2104605

End: 2105480

Strand: Reverse

Name: hisK [H]

Synonym: Nther_1995

Alternate gene names: 188586605

Gene position: 2105480-2104605 (Counterclockwise)

Preceding gene: 188586606

Following gene: 188586604

Centisome position: 66.51

GC content: 36.53

Gene sequence:

>876_bases
ATGCCGACAGATAACGAAAAGAAAACCGGTGCTCTAATATTTAAAACAAGGGGTGAGTTTTTGATAGACTATCATACTCA
TACTTGGAGATGTGGTCATGCAGAAGGGAATATTGAAGATTATGTTTTAAAGGCCATTGAAAGAGGATTGACCGAGATCG
GGATCAGTGACCATTATCCCATGGATGTATTAAATGTACCTTCGGAAGACATATCTTCTATGCTGTATCAGGATTTGCAA
ACGTATGTCAATGAAGTAAAAGAGGTAGCTCGGCGCTATGAATCCCAAATTACAGTTAGGTTAGGTACCGAAATGGATTA
TTTTAGGGATTTAAAATTAGGTTATAACCGCATTTTAGAAGAATACGACTGGGACTATGTGATAGGCTCTATTCACTTTT
TAGAAGGAAAGGACGTATCTCATCCCAAAAACCTAACATTCTACCAAAAAAACTCTTTAATAGACATTTACTGTAAATAT
TTTGATGAAATCAAAACCATGACAAATAGTGAGGAATTCGATATTATAGGTCATGTAGACGTGATTAAAAAACATGGTTA
CGTTCCTGAAGGTGAAAATTCAGTTAAAGAACTACAGGAGTTTTATTTAGAATTAGCCAGGTTGTTCGCTCAAAAACAGC
AGGTTGTGGAAATAAATACTGGCGGTTTAAGAGCTCCAGTTGAAGAAATATACCCCGCAGAGGACTTTTTAAACAAACTA
ATTTCTCATAATGTACCCTTAACCATTGGTTCTGATGCTCATCACCCCGACGAAGTTGGCTACAGTAATTCAGAAATAGT
TGGGTATTTAAAAGAAATGGGTGTTAACACTGTTGTCGGCTTTAAAAACAGACAGGCCTATGAAGTGCCACTATAA

Upstream 100 bases:

>100_bases
ATCATCCACGAATCTGCGGATTTGATTTTTCATACATTACTAGCATTAAAGTATTTTCAAGTGGATTTATCGGAAGTTTT
ACAAGAACTCCACAATAGAC

Downstream 100 bases:

>100_bases
AAGTCATTTTATAATTTGCTTGGGCTAAGAACTAGGAATTTTGACTAATTCGTTCTTAATTAATATAATATAATTTCGGA
AACAATTCAGAGTATGCCAG

Product: histidinol phosphate phosphatase HisJ family

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MPTDNEKKTGALIFKTRGEFLIDYHTHTWRCGHAEGNIEDYVLKAIERGLTEIGISDHYPMDVLNVPSEDISSMLYQDLQ
TYVNEVKEVARRYESQITVRLGTEMDYFRDLKLGYNRILEEYDWDYVIGSIHFLEGKDVSHPKNLTFYQKNSLIDIYCKY
FDEIKTMTNSEEFDIIGHVDVIKKHGYVPEGENSVKELQEFYLELARLFAQKQQVVEINTGGLRAPVEEIYPAEDFLNKL
ISHNVPLTIGSDAHHPDEVGYSNSEIVGYLKEMGVNTVVGFKNRQAYEVPL

Sequences:

>Translated_291_residues
MPTDNEKKTGALIFKTRGEFLIDYHTHTWRCGHAEGNIEDYVLKAIERGLTEIGISDHYPMDVLNVPSEDISSMLYQDLQ
TYVNEVKEVARRYESQITVRLGTEMDYFRDLKLGYNRILEEYDWDYVIGSIHFLEGKDVSHPKNLTFYQKNSLIDIYCKY
FDEIKTMTNSEEFDIIGHVDVIKKHGYVPEGENSVKELQEFYLELARLFAQKQQVVEINTGGLRAPVEEIYPAEDFLNKL
ISHNVPLTIGSDAHHPDEVGYSNSEIVGYLKEMGVNTVVGFKNRQAYEVPL
>Mature_290_residues
PTDNEKKTGALIFKTRGEFLIDYHTHTWRCGHAEGNIEDYVLKAIERGLTEIGISDHYPMDVLNVPSEDISSMLYQDLQT
YVNEVKEVARRYESQITVRLGTEMDYFRDLKLGYNRILEEYDWDYVIGSIHFLEGKDVSHPKNLTFYQKNSLIDIYCKYF
DEIKTMTNSEEFDIIGHVDVIKKHGYVPEGENSVKELQEFYLELARLFAQKQQVVEINTGGLRAPVEEIYPAEDFLNKLI
SHNVPLTIGSDAHHPDEVGYSNSEIVGYLKEMGVNTVVGFKNRQAYEVPL

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 33606; Mature: 33475

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTDNEKKTGALIFKTRGEFLIDYHTHTWRCGHAEGNIEDYVLKAIERGLTEIGISDHYP
CCCCCCCCCCEEEEEECCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
MDVLNVPSEDISSMLYQDLQTYVNEVKEVARRYESQITVRLGTEMDYFRDLKLGYNRILE
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHH
EYDWDYVIGSIHFLEGKDVSHPKNLTFYQKNSLIDIYCKYFDEIKTMTNSEEFDIIGHVD
HCCCCEEEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEHHH
VIKKHGYVPEGENSVKELQEFYLELARLFAQKQQVVEINTGGLRAPVEEIYPAEDFLNKL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHCCHHHHHHHH
ISHNVPLTIGSDAHHPDEVGYSNSEIVGYLKEMGVNTVVGFKNRQAYEVPL
HHCCCCEEECCCCCCCHHCCCCCHHHHHHHHHCCCCEEEECCCCCEEECCC
>Mature Secondary Structure 
PTDNEKKTGALIFKTRGEFLIDYHTHTWRCGHAEGNIEDYVLKAIERGLTEIGISDHYP
CCCCCCCCCEEEEEECCCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
MDVLNVPSEDISSMLYQDLQTYVNEVKEVARRYESQITVRLGTEMDYFRDLKLGYNRILE
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHH
EYDWDYVIGSIHFLEGKDVSHPKNLTFYQKNSLIDIYCKYFDEIKTMTNSEEFDIIGHVD
HCCCCEEEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEHHH
VIKKHGYVPEGENSVKELQEFYLELARLFAQKQQVVEINTGGLRAPVEEIYPAEDFLNKL
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHCCHHHHHHHH
ISHNVPLTIGSDAHHPDEVGYSNSEIVGYLKEMGVNTVVGFKNRQAYEVPL
HHCCCCEEECCCCCCCHHCCCCCHHHHHHHHHCCCCEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]