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The map label for this gene is ruvB [H]

Identifier: 188586411

GI number: 188586411

Start: 1861375

End: 1862400

Strand: Reverse

Name: ruvB [H]

Synonym: Nther_1796

Alternate gene names: 188586411

Gene position: 1862400-1861375 (Counterclockwise)

Preceding gene: 188586412

Following gene: 188586410

Centisome position: 58.83

GC content: 39.08

Gene sequence:

>1026_bases
ATGTCCTCAGATGAAAGAATTATTACTCGCCAGCAAGTGGGGGAAGACTATCAACTGGATAGCGATTTGCGTCCAAGAAA
ATTTGATGACTATATTGGTCAAGAAAAAGTAAAGACTAATCTAGAGATTTTTATTAAAGCTGCAGTTGAGCGTTCTGAAG
CTTTAGATCATGTGCTATTATACGGCCCTCCAGGATTGGGAAAAACTACTTTAGCCCATATAATTGCAGAACAAATGGGT
GTGAATATTCATGTGACATCAGGGCCTGCCATTGAGAGGCCTGGAGATTTAGCTGCTATTTTAACAAATTTAGAAGAACG
GGATGTCTTGTTTATTGATGAAATACACCGCTTGCCTAGAAGCGTGGAAGAAATTCTTTATCCTGCTTTAGAAGATTTTT
CGATAGATATTATGGTAGGAAAGGGACCAAGTGCTAGGAGCTTGCGCCTTGATTTAGCTCCCTTTACCTTAGTGGGAGCA
ACTACTAGAGCTGGTAGTCTATCTAGTCCTTTAAGAGATAGGTTTGGAGTTGTAAATAGACTGGATTTTTATTCAATGCA
AGATCTTTGTCAAATTGTGACTCGATCAGCAGACATTTTGGGAATAGAAATTACTGAAGAAGGGGCCAAAAAACTAGCTC
AAAGTTCTCGCGGCACTCCTCGGATAGCCAATAGATTATTGAAACGTGCCAGGGATTATGCTCAAGTTAAAGCCGATAAC
AAAATCACAGCAGAAGTTGCTGATAAAGCTTTGGAAATGCTCGAAGTGGATTCTTACGGATTAGATGAGATTGATAGAAG
ATTGATGCATACAATTTATAATAAATTTAGTGGTGGCCCCGTTGGCCTTGATACTATTGCTGCTGCCATTAGTGAAGAAG
CTGAAACTATTGAAGATGTTTATGAACCATTTTTGCTACAATTAGGTTTTTTACAGCGTACACCTAGAGGACGTGTACTA
ACTAAGGCAGCTAAGAATTACTTAGGCCTTTCTGATGACTCACCAGAGCAGCAAAAATTATTTTAG

Upstream 100 bases:

>100_bases
TGATGCAATTCAAGGACAAATAACGGAAGGGCAAGATATGGAAGAACTCTTGCGATTAGCTTTACAAAAATTAAACACGA
AATGATGAGGAGGAAAAATA

Downstream 100 bases:

>100_bases
GTGGACTCAGATCACTTACTTAATTCTAAAATAAGTTTTAAGTTATTTCTAAATTAATTCCTAATATTGTATCTAAATTA
TTTCACCTGAGGTGGTATCA

Product: Holliday junction DNA helicase subunit RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSSDERIITRQQVGEDYQLDSDLRPRKFDDYIGQEKVKTNLEIFIKAAVERSEALDHVLLYGPPGLGKTTLAHIIAEQMG
VNIHVTSGPAIERPGDLAAILTNLEERDVLFIDEIHRLPRSVEEILYPALEDFSIDIMVGKGPSARSLRLDLAPFTLVGA
TTRAGSLSSPLRDRFGVVNRLDFYSMQDLCQIVTRSADILGIEITEEGAKKLAQSSRGTPRIANRLLKRARDYAQVKADN
KITAEVADKALEMLEVDSYGLDEIDRRLMHTIYNKFSGGPVGLDTIAAAISEEAETIEDVYEPFLLQLGFLQRTPRGRVL
TKAAKNYLGLSDDSPEQQKLF

Sequences:

>Translated_341_residues
MSSDERIITRQQVGEDYQLDSDLRPRKFDDYIGQEKVKTNLEIFIKAAVERSEALDHVLLYGPPGLGKTTLAHIIAEQMG
VNIHVTSGPAIERPGDLAAILTNLEERDVLFIDEIHRLPRSVEEILYPALEDFSIDIMVGKGPSARSLRLDLAPFTLVGA
TTRAGSLSSPLRDRFGVVNRLDFYSMQDLCQIVTRSADILGIEITEEGAKKLAQSSRGTPRIANRLLKRARDYAQVKADN
KITAEVADKALEMLEVDSYGLDEIDRRLMHTIYNKFSGGPVGLDTIAAAISEEAETIEDVYEPFLLQLGFLQRTPRGRVL
TKAAKNYLGLSDDSPEQQKLF
>Mature_340_residues
SSDERIITRQQVGEDYQLDSDLRPRKFDDYIGQEKVKTNLEIFIKAAVERSEALDHVLLYGPPGLGKTTLAHIIAEQMGV
NIHVTSGPAIERPGDLAAILTNLEERDVLFIDEIHRLPRSVEEILYPALEDFSIDIMVGKGPSARSLRLDLAPFTLVGAT
TRAGSLSSPLRDRFGVVNRLDFYSMQDLCQIVTRSADILGIEITEEGAKKLAQSSRGTPRIANRLLKRARDYAQVKADNK
ITAEVADKALEMLEVDSYGLDEIDRRLMHTIYNKFSGGPVGLDTIAAAISEEAETIEDVYEPFLLQLGFLQRTPRGRVLT
KAAKNYLGLSDDSPEQQKLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=205, Percent_Identity=27.8048780487805, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788167, Length=312, Percent_Identity=61.5384615384615, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI1787119, Length=189, Percent_Identity=32.2751322751323, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37960; Mature: 37829

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDERIITRQQVGEDYQLDSDLRPRKFDDYIGQEKVKTNLEIFIKAAVERSEALDHVLL
CCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHCCHHHHHHHHHHHHHHHCEEEE
YGPPGLGKTTLAHIIAEQMGVNIHVTSGPAIERPGDLAAILTNLEERDVLFIDEIHRLPR
ECCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
SVEEILYPALEDFSIDIMVGKGPSARSLRLDLAPFTLVGATTRAGSLSSPLRDRFGVVNR
HHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHH
LDFYSMQDLCQIVTRSADILGIEITEEGAKKLAQSSRGTPRIANRLLKRARDYAQVKADN
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
KITAEVADKALEMLEVDSYGLDEIDRRLMHTIYNKFSGGPVGLDTIAAAISEEAETIEDV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YEPFLLQLGFLQRTPRGRVLTKAAKNYLGLSDDSPEQQKLF
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCC
>Mature Secondary Structure 
SSDERIITRQQVGEDYQLDSDLRPRKFDDYIGQEKVKTNLEIFIKAAVERSEALDHVLL
CCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHCHHHHHCCHHHHHHHHHHHHHHHCEEEE
YGPPGLGKTTLAHIIAEQMGVNIHVTSGPAIERPGDLAAILTNLEERDVLFIDEIHRLPR
ECCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
SVEEILYPALEDFSIDIMVGKGPSARSLRLDLAPFTLVGATTRAGSLSSPLRDRFGVVNR
HHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHH
LDFYSMQDLCQIVTRSADILGIEITEEGAKKLAQSSRGTPRIANRLLKRARDYAQVKADN
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
KITAEVADKALEMLEVDSYGLDEIDRRLMHTIYNKFSGGPVGLDTIAAAISEEAETIEDV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
YEPFLLQLGFLQRTPRGRVLTKAAKNYLGLSDDSPEQQKLF
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA