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The map label for this gene is gtaB [H]

Identifier: 188586201

GI number: 188586201

Start: 1664361

End: 1665227

Strand: Direct

Name: gtaB [H]

Synonym: Nther_1583

Alternate gene names: 188586201

Gene position: 1664361-1665227 (Clockwise)

Preceding gene: 188586200

Following gene: 188586203

Centisome position: 52.58

GC content: 32.3

Gene sequence:

>867_bases
TTGAACATTAAAAAAGCAATCATACCTGTCGCAGGCTTTGGTACTAGACTTTTACCTATTACCAAAGCCATCCCTAAAAC
AATGTTACCTATCGTGGATAAACCAGTGATACATTACCTGGTTGAAGAAGCTGTGGCTTCAGGTATTGAAGAGATTATAA
TTATTACAGGTCAGAAAAGAAAAAACATTGAAGATTATTTCAATAGATCTCAGGAGCTGGAAGAACATCTAATTAAAACG
GGTAAAGAAGATTTGTTAGAACAGATCAAAAATATATCAAATCAGGCTAATATCAATTACGTAGCTCAGGATAGCGCTCT
TGGTCTTGGGCATGCAATATATTGTGGTCGCAAATTTATAGATAAAGATGAATCATTTGCAGTTTTACTCGGTGATGATA
TAGTTAGAGCAAAAAAGCCATGTATAGCACAATTGATAGATGTCTACAGGAAATATCGATCTAATATTATTGGCGTTCAG
AGTGTTCCCGACGAAGAAGTAAGTAAATATGGTATTGTAAATGGGAAAAGAATAAATAATAAATTAGTCAAAGTAAGTGA
CTTAGTCGAAAAGCCAGACAAGGAAAATACTCCTTCTAATTTAGCCATTCTAGGTAGATATATTATTCATAGTGATATTT
TCGATGTATTAGAAGTTATCGGTCCTGGTGCAGGTGGAGAAATTCAGTTAACAGATGCTTTAAAAGCACTTAATTACAAT
CAAAATATCTATTCTTACAGCTTTGAAGGAACTAGATACGATACAGGTGATAAATTAGGTTATTTAATCGCAAATATTGA
ATTTGCCTTACAAAACAATGAATTAAAAAATAATTTAAAAAATAAAGTAAAGCCCCTTTTCTTTTAG

Upstream 100 bases:

>100_bases
AGAAAAATCCTTGATTACGATCCTGAAATAACTCTTGAAGATGGGCTCAAAAAAACCTTAAATTGGTATAAAGACAGAGT
ATGATTAGGAGTGAGTAATT

Downstream 100 bases:

>100_bases
GGGCTTTACTTTATTTTGCTCATTCATATACAAATAATTTAACCCCGGGATGTAATCCCGGGGTGTTTGATGGCACTATG
TTAATCGTTCACATTTAATT

Product: UDP-glucose pyrophosphorylase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNIKKAIIPVAGFGTRLLPITKAIPKTMLPIVDKPVIHYLVEEAVASGIEEIIIITGQKRKNIEDYFNRSQELEEHLIKT
GKEDLLEQIKNISNQANINYVAQDSALGLGHAIYCGRKFIDKDESFAVLLGDDIVRAKKPCIAQLIDVYRKYRSNIIGVQ
SVPDEEVSKYGIVNGKRINNKLVKVSDLVEKPDKENTPSNLAILGRYIIHSDIFDVLEVIGPGAGGEIQLTDALKALNYN
QNIYSYSFEGTRYDTGDKLGYLIANIEFALQNNELKNNLKNKVKPLFF

Sequences:

>Translated_288_residues
MNIKKAIIPVAGFGTRLLPITKAIPKTMLPIVDKPVIHYLVEEAVASGIEEIIIITGQKRKNIEDYFNRSQELEEHLIKT
GKEDLLEQIKNISNQANINYVAQDSALGLGHAIYCGRKFIDKDESFAVLLGDDIVRAKKPCIAQLIDVYRKYRSNIIGVQ
SVPDEEVSKYGIVNGKRINNKLVKVSDLVEKPDKENTPSNLAILGRYIIHSDIFDVLEVIGPGAGGEIQLTDALKALNYN
QNIYSYSFEGTRYDTGDKLGYLIANIEFALQNNELKNNLKNKVKPLFF
>Mature_288_residues
MNIKKAIIPVAGFGTRLLPITKAIPKTMLPIVDKPVIHYLVEEAVASGIEEIIIITGQKRKNIEDYFNRSQELEEHLIKT
GKEDLLEQIKNISNQANINYVAQDSALGLGHAIYCGRKFIDKDESFAVLLGDDIVRAKKPCIAQLIDVYRKYRSNIIGVQ
SVPDEEVSKYGIVNGKRINNKLVKVSDLVEKPDKENTPSNLAILGRYIIHSDIFDVLEVIGPGAGGEIQLTDALKALNYN
QNIYSYSFEGTRYDTGDKLGYLIANIEFALQNNELKNNLKNKVKPLFF

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=288, Percent_Identity=42.0138888888889, Blast_Score=213, Evalue=8e-57,
Organism=Escherichia coli, GI1788355, Length=278, Percent_Identity=38.8489208633094, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI1788351, Length=264, Percent_Identity=30.6818181818182, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790224, Length=261, Percent_Identity=29.1187739463602, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI133931050, Length=259, Percent_Identity=24.7104247104247, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32265; Mature: 32265

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKKAIIPVAGFGTRLLPITKAIPKTMLPIVDKPVIHYLVEEAVASGIEEIIIITGQKR
CCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCC
KNIEDYFNRSQELEEHLIKTGKEDLLEQIKNISNQANINYVAQDSALGLGHAIYCGRKFI
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHC
DKDESFAVLLGDDIVRAKKPCIAQLIDVYRKYRSNIIGVQSVPDEEVSKYGIVNGKRINN
CCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHCCCCCCCCCC
KLVKVSDLVEKPDKENTPSNLAILGRYIIHSDIFDVLEVIGPGAGGEIQLTDALKALNYN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCC
QNIYSYSFEGTRYDTGDKLGYLIANIEFALQNNELKNNLKNKVKPLFF
CCEEEEECCCCEECCCCHHHHHEEEEEEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNIKKAIIPVAGFGTRLLPITKAIPKTMLPIVDKPVIHYLVEEAVASGIEEIIIITGQKR
CCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCC
KNIEDYFNRSQELEEHLIKTGKEDLLEQIKNISNQANINYVAQDSALGLGHAIYCGRKFI
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHC
DKDESFAVLLGDDIVRAKKPCIAQLIDVYRKYRSNIIGVQSVPDEEVSKYGIVNGKRINN
CCCCCEEEEECCHHHHHCCHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHCCCCCCCCCC
KLVKVSDLVEKPDKENTPSNLAILGRYIIHSDIFDVLEVIGPGAGGEIQLTDALKALNYN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCC
QNIYSYSFEGTRYDTGDKLGYLIANIEFALQNNELKNNLKNKVKPLFF
CCEEEEECCCCEECCCCHHHHHEEEEEEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]