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The map label for this gene is menC [H]

Identifier: 188586165

GI number: 188586165

Start: 1626413

End: 1627588

Strand: Reverse

Name: menC [H]

Synonym: Nther_1544

Alternate gene names: 188586165

Gene position: 1627588-1626413 (Counterclockwise)

Preceding gene: 188586168

Following gene: 188586164

Centisome position: 51.42

GC content: 33.84

Gene sequence:

>1176_bases
ATGAAAGAACAAGCTATCATCGAAAAAGTAAGAATCATTGAAGTCAATATGCCTTTTACAAATCATATTCAGGTGGGAGA
AAGCTCTAATAAACTTCGAAAATCATTAATCATTGAGTTACACTCAGAAGGTATTATTGGCTATGGAGAGTCTGCGCCTT
ACGGCGAACCATTCTATTCAGGAGAGACCATTTCTACAGTAAAGCCTATCCTCAAAGAAAACATTTTACCTAAAATAGTA
GGAAAAGAAATCAGTTCAATTGAACAATTAAATCAATTAATCAACACCCAGATAAAAGGTAATAACTTTGCCAAGGCCGG
GGTAGAAACGGCCTATTGGGATTTAATAGCTAAGAAAAGAAATATACCATTAAAACAACTCATTCACGAAAAATTAATGG
AAATCGGGGTGAATGACCCTTCTTTAAATAATACCAATTATATTTTAAGTGGTGCTGCAATGGGTATTCCCCCGGGAGAA
AAAGAAGACAATTTAGTAGAACAAGTAAAAAGTGCTTTGGAAGAAGGTTATCAAAAAATTAAAATAAAAGTGTCTCCAGG
ATTTGATATCAATGCCATAGAAAAAGTTTTGAAAGTTATACCTGATGATATAAATTTTTGGATGGATGCTAGCGCTTCAT
ATAACATAAAAAATCATTTACCGATATTAAAACAAATTGACTCTTACAATATTGATTTTTTAGAACAGCCTTTAGCACAT
GACGATATTTTAGAGCATAGCCAGTTAAGCCAAGAAGTGACTACTCCCATCTGTTTAGATGAATCTTTATATTCTGCAAA
GATAGCGGAAAATTCTCTTGGTCTCGGTTTTAACCAAATTTGGAACATTAAAATCCAACGCATCGGTGGGCTATTAGAGG
CGCTTAAGATTTATAAGTTAGCATCTGAAAATAACGTCAGTGTGTGGGGCGGTACTATGCCTGAAACTGGTATTGGAGCT
ATTTTTATGTTAGCTCTTGGAACTTATTCAAACTTTACTTATCCTTCAGATGTTGCAGATAGCACGAAATGGTATGGTAA
TAATAACGATCTAAAGGATTTAAAAATGACCGGGGAGGGGAAAATCTTCTACTCCGATGAGATAGGAATTGGTGAAATCA
ATCATTATAATTATAGAAAATATGGACATTTAGTTCATGAAGTAAATGGGTATTAA

Upstream 100 bases:

>100_bases
TCGTAGATATAATGAACAGGAGCTAATTAACTATCAATTACTTGGGTAAAATAAACATAATTTAAATAACTTTATAAATA
GTAGTTGAAGGAGGAACAAT

Downstream 100 bases:

>100_bases
GCCTTAATTTTTAATAACTCCCAAAAAACTGCCCTTCACACTTAGCCGTGAAGGGCTTCTTATTTTCTTTAGAGGGATAT
AGCTCTTTTTAGAAAGAAAA

Product: Mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKEQAIIEKVRIIEVNMPFTNHIQVGESSNKLRKSLIIELHSEGIIGYGESAPYGEPFYSGETISTVKPILKENILPKIV
GKEISSIEQLNQLINTQIKGNNFAKAGVETAYWDLIAKKRNIPLKQLIHEKLMEIGVNDPSLNNTNYILSGAAMGIPPGE
KEDNLVEQVKSALEEGYQKIKIKVSPGFDINAIEKVLKVIPDDINFWMDASASYNIKNHLPILKQIDSYNIDFLEQPLAH
DDILEHSQLSQEVTTPICLDESLYSAKIAENSLGLGFNQIWNIKIQRIGGLLEALKIYKLASENNVSVWGGTMPETGIGA
IFMLALGTYSNFTYPSDVADSTKWYGNNNDLKDLKMTGEGKIFYSDEIGIGEINHYNYRKYGHLVHEVNGY

Sequences:

>Translated_391_residues
MKEQAIIEKVRIIEVNMPFTNHIQVGESSNKLRKSLIIELHSEGIIGYGESAPYGEPFYSGETISTVKPILKENILPKIV
GKEISSIEQLNQLINTQIKGNNFAKAGVETAYWDLIAKKRNIPLKQLIHEKLMEIGVNDPSLNNTNYILSGAAMGIPPGE
KEDNLVEQVKSALEEGYQKIKIKVSPGFDINAIEKVLKVIPDDINFWMDASASYNIKNHLPILKQIDSYNIDFLEQPLAH
DDILEHSQLSQEVTTPICLDESLYSAKIAENSLGLGFNQIWNIKIQRIGGLLEALKIYKLASENNVSVWGGTMPETGIGA
IFMLALGTYSNFTYPSDVADSTKWYGNNNDLKDLKMTGEGKIFYSDEIGIGEINHYNYRKYGHLVHEVNGY
>Mature_391_residues
MKEQAIIEKVRIIEVNMPFTNHIQVGESSNKLRKSLIIELHSEGIIGYGESAPYGEPFYSGETISTVKPILKENILPKIV
GKEISSIEQLNQLINTQIKGNNFAKAGVETAYWDLIAKKRNIPLKQLIHEKLMEIGVNDPSLNNTNYILSGAAMGIPPGE
KEDNLVEQVKSALEEGYQKIKIKVSPGFDINAIEKVLKVIPDDINFWMDASASYNIKNHLPILKQIDSYNIDFLEQPLAH
DDILEHSQLSQEVTTPICLDESLYSAKIAENSLGLGFNQIWNIKIQRIGGLLEALKIYKLASENNVSVWGGTMPETGIGA
IFMLALGTYSNFTYPSDVADSTKWYGNNNDLKDLKMTGEGKIFYSDEIGIGEINHYNYRKYGHLVHEVNGY

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081876, Length=309, Percent_Identity=23.9482200647249, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354
- InterPro:   IPR010197 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 43750; Mature: 43750

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQAIIEKVRIIEVNMPFTNHIQVGESSNKLRKSLIIELHSEGIIGYGESAPYGEPFYS
CCCHHHHCEEEEEEEECCCCCCEEECCCHHHHHHHHHHEECCCCCEECCCCCCCCCCCCC
GETISTVKPILKENILPKIVGKEISSIEQLNQLINTQIKGNNFAKAGVETAYWDLIAKKR
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHC
NIPLKQLIHEKLMEIGVNDPSLNNTNYILSGAAMGIPPGEKEDNLVEQVKSALEEGYQKI
CCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCEECCCCCCCCHHHHHHHHHHHHCCHHEE
KIKVSPGFDINAIEKVLKVIPDDINFWMDASASYNIKNHLPILKQIDSYNIDFLEQPLAH
EEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCHHHCCCHHHHHCCCCCHHHHCCCCH
DDILEHSQLSQEVTTPICLDESLYSAKIAENSLGLGFNQIWNIKIQRIGGLLEALKIYKL
HHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHH
ASENNVSVWGGTMPETGIGAIFMLALGTYSNFTYPSDVADSTKWYGNNNDLKDLKMTGEG
CCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
KIFYSDEIGIGEINHYNYRKYGHLVHEVNGY
EEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEQAIIEKVRIIEVNMPFTNHIQVGESSNKLRKSLIIELHSEGIIGYGESAPYGEPFYS
CCCHHHHCEEEEEEEECCCCCCEEECCCHHHHHHHHHHEECCCCCEECCCCCCCCCCCCC
GETISTVKPILKENILPKIVGKEISSIEQLNQLINTQIKGNNFAKAGVETAYWDLIAKKR
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHC
NIPLKQLIHEKLMEIGVNDPSLNNTNYILSGAAMGIPPGEKEDNLVEQVKSALEEGYQKI
CCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCEECCCCCCCCHHHHHHHHHHHHCCHHEE
KIKVSPGFDINAIEKVLKVIPDDINFWMDASASYNIKNHLPILKQIDSYNIDFLEQPLAH
EEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCHHHCCCHHHHHCCCCCHHHHCCCCH
DDILEHSQLSQEVTTPICLDESLYSAKIAENSLGLGFNQIWNIKIQRIGGLLEALKIYKL
HHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHH
ASENNVSVWGGTMPETGIGAIFMLALGTYSNFTYPSDVADSTKWYGNNNDLKDLKMTGEG
CCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
KIFYSDEIGIGEINHYNYRKYGHLVHEVNGY
EEEEECCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377; 10194342 [H]