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The map label for this gene is sufS [C]

Identifier: 188586168

GI number: 188586168

Start: 1630120

End: 1631265

Strand: Reverse

Name: sufS [C]

Synonym: Nther_1547

Alternate gene names: 188586168

Gene position: 1631265-1630120 (Counterclockwise)

Preceding gene: 188586169

Following gene: 188586165

Centisome position: 51.53

GC content: 37.17

Gene sequence:

>1146_bases
TTGAAGATGAACCGTGAACTTGTGATGATACCAGGACCAACTCCGGTCACTGAACCAATTCGAAACGAGATGGAAAGAGA
AACAGCGGCTTTTAAAGATCCCAATTTTATTGAAGACTTTCAACAAGTAATATCTGACCTTAAGAATTTATGGGGAAGTA
GTGAAGTGTTTGTTGTTGCTGGTTCCGGAACTCTTTCAATGGAAATGGCTATATCTAACACTCTTAAAAAATCTGATCCA
GTATTGGTGATATCTCATGGTTTTTTTGGAGATAGAATGGCAGAACTCTGTGAAAGAAAAGGATTGGAAGTAGACGTCCT
ATCATGTGAATGGGGAAAGGCAGTACCTGTAGAAGAAGTTGAAAAAAAGTTGTCAAATAAAAATTATCGGGCAGTGACAG
TTACCCATGTAGACACATCAACTGGTACCAAGGCACCACTTGAAGAGCTTGGAAAATTATTGGATAAGCATCAAGACACA
CTGTTTATAGTTGATGGTGTATGCTCTACTGCAGGAGAACCTGAATTTATTAATGAAATGGGGATTGACATCCTGCTCAC
TGCTTCACAAAAAGCCTTTGGAGTACCGCCAGGTCTTGCTATAGTTTGGGCAAGTGATAAAGCTTTAAAAAGAAGAGAAA
AAATCGGGGAAATCTCTGAATACTATGCTGACTTTAATAAATGGCTGCCAATAATGAATGATCCCAGTAAATATTTTGGC
ACTCCACCCGTTAATCTAATTTGGGCTTTAAAAAAATCTTTAGAATTTATTAAAACAGAAGGACTGAAAGAACGGTTTAA
GCGCCATCAAGTTAGAGGTAAAGCAATTCAGAAAGCTTTGGAAGGTATAGGTTTAAATATATTGGCAGAAGAAGGTGCCC
GTGCATCTACAATCTCTAACGCACTCTATCCAGAAGGAATTGATGATACATTCCGGAAAGTTCTTAAAGAAGAGGGAGTT
GTAGTAGCAGGTGGACTTGGGCCTTATGCTGACAAACTATTTAGGTTAGGGCATATGGGCAATATAGATATTAACGAATT
GGTTACAGTGATATCATCTATAGAGAGAACTTTATTCAGATTAGATTATCCAGTTGAATTTGGTAAAGGAGTTAATATTT
TTCTAGATAATATTATGAGAAATTAA

Upstream 100 bases:

>100_bases
CAACTTGTAATATTTTATGGAGCGATTTAATATTTATTAGACTAACGAAAATTCTAATATACACTTGTCCATGATAAAAA
CTTTGGGGGGGTGGTTCTAA

Downstream 100 bases:

>100_bases
TATTATTCAATATTAATAATCAAATATTCAAAGCACAAGAAAACCAGCTGGAAATGCATCAGCTGGTTTTCTATGTTCAA
ACCGATTTAGCTCCTTCACA

Product: aminotransferase class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKMNRELVMIPGPTPVTEPIRNEMERETAAFKDPNFIEDFQQVISDLKNLWGSSEVFVVAGSGTLSMEMAISNTLKKSDP
VLVISHGFFGDRMAELCERKGLEVDVLSCEWGKAVPVEEVEKKLSNKNYRAVTVTHVDTSTGTKAPLEELGKLLDKHQDT
LFIVDGVCSTAGEPEFINEMGIDILLTASQKAFGVPPGLAIVWASDKALKRREKIGEISEYYADFNKWLPIMNDPSKYFG
TPPVNLIWALKKSLEFIKTEGLKERFKRHQVRGKAIQKALEGIGLNILAEEGARASTISNALYPEGIDDTFRKVLKEEGV
VVAGGLGPYADKLFRLGHMGNIDINELVTVISSIERTLFRLDYPVEFGKGVNIFLDNIMRN

Sequences:

>Translated_381_residues
MKMNRELVMIPGPTPVTEPIRNEMERETAAFKDPNFIEDFQQVISDLKNLWGSSEVFVVAGSGTLSMEMAISNTLKKSDP
VLVISHGFFGDRMAELCERKGLEVDVLSCEWGKAVPVEEVEKKLSNKNYRAVTVTHVDTSTGTKAPLEELGKLLDKHQDT
LFIVDGVCSTAGEPEFINEMGIDILLTASQKAFGVPPGLAIVWASDKALKRREKIGEISEYYADFNKWLPIMNDPSKYFG
TPPVNLIWALKKSLEFIKTEGLKERFKRHQVRGKAIQKALEGIGLNILAEEGARASTISNALYPEGIDDTFRKVLKEEGV
VVAGGLGPYADKLFRLGHMGNIDINELVTVISSIERTLFRLDYPVEFGKGVNIFLDNIMRN
>Mature_381_residues
MKMNRELVMIPGPTPVTEPIRNEMERETAAFKDPNFIEDFQQVISDLKNLWGSSEVFVVAGSGTLSMEMAISNTLKKSDP
VLVISHGFFGDRMAELCERKGLEVDVLSCEWGKAVPVEEVEKKLSNKNYRAVTVTHVDTSTGTKAPLEELGKLLDKHQDT
LFIVDGVCSTAGEPEFINEMGIDILLTASQKAFGVPPGLAIVWASDKALKRREKIGEISEYYADFNKWLPIMNDPSKYFG
TPPVNLIWALKKSLEFIKTEGLKERFKRHQVRGKAIQKALEGIGLNILAEEGARASTISNALYPEGIDDTFRKVLKEEGV
VVAGGLGPYADKLFRLGHMGNIDINELVTVISSIERTLFRLDYPVEFGKGVNIFLDNIMRN

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=376, Percent_Identity=28.4574468085106, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17536281, Length=358, Percent_Identity=29.608938547486, Blast_Score=171, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6321079, Length=369, Percent_Identity=34.4173441734417, Blast_Score=189, Evalue=6e-49,
Organism=Drosophila melanogaster, GI17530823, Length=359, Percent_Identity=28.4122562674095, Blast_Score=143, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42398; Mature: 42398

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNRELVMIPGPTPVTEPIRNEMERETAAFKDPNFIEDFQQVISDLKNLWGSSEVFVVA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
GSGTLSMEMAISNTLKKSDPVLVISHGFFGDRMAELCERKGLEVDVLSCEWGKAVPVEEV
CCCCEEEHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
EKKLSNKNYRAVTVTHVDTSTGTKAPLEELGKLLDKHQDTLFIVDGVCSTAGEPEFINEM
HHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECHHCCCCCCHHHHHC
GIDILLTASQKAFGVPPGLAIVWASDKALKRREKIGEISEYYADFNKWLPIMNDPSKYFG
CCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
TPPVNLIWALKKSLEFIKTEGLKERFKRHQVRGKAIQKALEGIGLNILAEEGARASTISN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ALYPEGIDDTFRKVLKEEGVVVAGGLGPYADKLFRLGHMGNIDINELVTVISSIERTLFR
CCCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LDYPVEFGKGVNIFLDNIMRN
CCCCHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MKMNRELVMIPGPTPVTEPIRNEMERETAAFKDPNFIEDFQQVISDLKNLWGSSEVFVVA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEE
GSGTLSMEMAISNTLKKSDPVLVISHGFFGDRMAELCERKGLEVDVLSCEWGKAVPVEEV
CCCCEEEHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCHHHH
EKKLSNKNYRAVTVTHVDTSTGTKAPLEELGKLLDKHQDTLFIVDGVCSTAGEPEFINEM
HHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECHHCCCCCCHHHHHC
GIDILLTASQKAFGVPPGLAIVWASDKALKRREKIGEISEYYADFNKWLPIMNDPSKYFG
CCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCC
TPPVNLIWALKKSLEFIKTEGLKERFKRHQVRGKAIQKALEGIGLNILAEEGARASTISN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHH
ALYPEGIDDTFRKVLKEEGVVVAGGLGPYADKLFRLGHMGNIDINELVTVISSIERTLFR
CCCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LDYPVEFGKGVNIFLDNIMRN
CCCCHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]