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The map label for this gene is murA [H]

Identifier: 188585931

GI number: 188585931

Start: 1378475

End: 1379767

Strand: Direct

Name: murA [H]

Synonym: Nther_1305

Alternate gene names: 188585931

Gene position: 1378475-1379767 (Clockwise)

Preceding gene: 188585930

Following gene: 188585932

Centisome position: 43.55

GC content: 37.43

Gene sequence:

>1293_bases
ATGTGTAAATTTGTGGTATCGGGACAGAAACGGCTTCATGGAAAAATAAAAGTACACGGTGCAAAAAACTCTGCACTCCC
CTTATTAGCAGGTTCTCTTTTATCCAGTGAGCTTGTGAGGTTAAGGGAGATACCGCAGTTACGAGATGTTAAAGTTATGA
AAGAAATTATTAAAAGTTTAGGTGGATATGTAATTGAGGATGGTAATGGTGTTAGCGTTAATCCAGGAGAAATTGAAACA
GGTATAATACCAAAAAGATTAATGAGTGAAATGAGATCTAGTATTGTATTATTAGCAGGTATTTTGCATAATCTTGGGTG
GGTAAAGATATATCCACCTGGTGGTTGTGCTATTGGAAAAAGGCCAATTGATTTACATCTAAAAGGACTAGAACAGCTGG
GATGTGAAGTGAAACAGTATCAAGAGTCTATAGTTTTGACTGCTCCGGATGGCTTAAAGGGAGCGAAAATTAAACTTGAC
TATCCTAGTGTTGGTGCTACAGAAAATATAATGATGGCTGCAGCCAAGGCTAAAGGTGTTACTGAAATTCTAAATCCTGC
AAAAGAGCCTGAAATTCAAGATTTGGCTAATTTTATTAATTCAATGGGTGGTGAAGTAAAAGGGGCTGGCACTGATAAGA
TTACAGTAGTTGGTAAAGAGGTTTTACATGGTACTGATTATCAAATTATACCTGACCGAATTGCTGCTGGCACATACATG
GTAGCGACGGCAATTACCGGAGGTGAAGTCACTTTAACAAATGTAGTACCTTCTCATGTCGAAAAAACAGTAAATTTATT
AGAAAAGTGTGGTGTGCAAGTTGTAGTTGGAGATAGAAATATATCTGTTTCTGCAAAAAATCGCCAGTTGAATTCACCGG
GTAAGATAGAAACAAATCCATATCCTGGCTTTCCTACAGATATGCAACCGCAATTTATGGCACTAAGTTGTTTACTAACC
GGCTCTACAAAAATAACTGAAAATATTTTTGAGGGTAGATTCAAGCATGTCTCTGAACTATTAAAAATGGGAGCAGATAT
TAGTATTGAGGGTAACTATGCTATTGTAAAAGGAAATAGTGCTTTATCTGGAACCGTTGTGAAAGCTTCTGACTTAAGAG
CAGGGGCTGCTCTTACCCTGGCAGCACTAGCTGCCGAAGGTGTTACAATTATTGAAAATATTGATCATATTGACCGTGGT
TACGAGGACTTTGATAGAGACTTAAATGCTCTTGGAGCCAATATGTTTAGAATTTCCAATCATTCGGATATAAAAAGTGA
TGAAAACGCCTAA

Upstream 100 bases:

>100_bases
ATTAGAAAAGGGACAAGCGTAATTAACACCAGTTAAATTTATTGCATATCATAAACCAAGATTCAAGATTAAGGTTATGC
AATTAATTGGGGGTGCCTGA

Downstream 100 bases:

>100_bases
TTATTAGGCGTTTTCAGGGGGTTTTTTATGGACAAGCTAATGAGAAAAAAATCGACTAAAAACAAAAAAATCAGACCCAA
AAAGACAATTTGGGTAGTCC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MCKFVVSGQKRLHGKIKVHGAKNSALPLLAGSLLSSELVRLREIPQLRDVKVMKEIIKSLGGYVIEDGNGVSVNPGEIET
GIIPKRLMSEMRSSIVLLAGILHNLGWVKIYPPGGCAIGKRPIDLHLKGLEQLGCEVKQYQESIVLTAPDGLKGAKIKLD
YPSVGATENIMMAAAKAKGVTEILNPAKEPEIQDLANFINSMGGEVKGAGTDKITVVGKEVLHGTDYQIIPDRIAAGTYM
VATAITGGEVTLTNVVPSHVEKTVNLLEKCGVQVVVGDRNISVSAKNRQLNSPGKIETNPYPGFPTDMQPQFMALSCLLT
GSTKITENIFEGRFKHVSELLKMGADISIEGNYAIVKGNSALSGTVVKASDLRAGAALTLAALAAEGVTIIENIDHIDRG
YEDFDRDLNALGANMFRISNHSDIKSDENA

Sequences:

>Translated_430_residues
MCKFVVSGQKRLHGKIKVHGAKNSALPLLAGSLLSSELVRLREIPQLRDVKVMKEIIKSLGGYVIEDGNGVSVNPGEIET
GIIPKRLMSEMRSSIVLLAGILHNLGWVKIYPPGGCAIGKRPIDLHLKGLEQLGCEVKQYQESIVLTAPDGLKGAKIKLD
YPSVGATENIMMAAAKAKGVTEILNPAKEPEIQDLANFINSMGGEVKGAGTDKITVVGKEVLHGTDYQIIPDRIAAGTYM
VATAITGGEVTLTNVVPSHVEKTVNLLEKCGVQVVVGDRNISVSAKNRQLNSPGKIETNPYPGFPTDMQPQFMALSCLLT
GSTKITENIFEGRFKHVSELLKMGADISIEGNYAIVKGNSALSGTVVKASDLRAGAALTLAALAAEGVTIIENIDHIDRG
YEDFDRDLNALGANMFRISNHSDIKSDENA
>Mature_430_residues
MCKFVVSGQKRLHGKIKVHGAKNSALPLLAGSLLSSELVRLREIPQLRDVKVMKEIIKSLGGYVIEDGNGVSVNPGEIET
GIIPKRLMSEMRSSIVLLAGILHNLGWVKIYPPGGCAIGKRPIDLHLKGLEQLGCEVKQYQESIVLTAPDGLKGAKIKLD
YPSVGATENIMMAAAKAKGVTEILNPAKEPEIQDLANFINSMGGEVKGAGTDKITVVGKEVLHGTDYQIIPDRIAAGTYM
VATAITGGEVTLTNVVPSHVEKTVNLLEKCGVQVVVGDRNISVSAKNRQLNSPGKIETNPYPGFPTDMQPQFMALSCLLT
GSTKITENIFEGRFKHVSELLKMGADISIEGNYAIVKGNSALSGTVVKASDLRAGAALTLAALAAEGVTIIENIDHIDRG
YEDFDRDLNALGANMFRISNHSDIKSDENA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=43.1980906921241, Blast_Score=330, Evalue=8e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45973; Mature: 45973

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKFVVSGQKRLHGKIKVHGAKNSALPLLAGSLLSSELVRLREIPQLRDVKVMKEIIKSL
CCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGYVIEDGNGVSVNPGEIETGIIPKRLMSEMRSSIVLLAGILHNLGWVKIYPPGGCAIGK
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
RPIDLHLKGLEQLGCEVKQYQESIVLTAPDGLKGAKIKLDYPSVGATENIMMAAAKAKGV
CCCEEEEHHHHHHCHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCH
TEILNPAKEPEIQDLANFINSMGGEVKGAGTDKITVVGKEVLHGTDYQIIPDRIAAGTYM
HHHHCCCCCCCHHHHHHHHHHCCCCEECCCCCEEEEEEHHHHCCCCCEECCHHHCCCEEE
VATAITGGEVTLTNVVPSHVEKTVNLLEKCGVQVVVGDRNISVSAKNRQLNSPGKIETNP
EEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCCCCC
YPGFPTDMQPQFMALSCLLTGSTKITENIFEGRFKHVSELLKMGADISIEGNYAIVKGNS
CCCCCCCCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCC
ALSGTVVKASDLRAGAALTLAALAAEGVTIIENIDHIDRGYEDFDRDLNALGANMFRISN
CCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECC
HSDIKSDENA
CCCCCCCCCC
>Mature Secondary Structure
MCKFVVSGQKRLHGKIKVHGAKNSALPLLAGSLLSSELVRLREIPQLRDVKVMKEIIKSL
CCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GGYVIEDGNGVSVNPGEIETGIIPKRLMSEMRSSIVLLAGILHNLGWVKIYPPGGCAIGK
CCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
RPIDLHLKGLEQLGCEVKQYQESIVLTAPDGLKGAKIKLDYPSVGATENIMMAAAKAKGV
CCCEEEEHHHHHHCHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCH
TEILNPAKEPEIQDLANFINSMGGEVKGAGTDKITVVGKEVLHGTDYQIIPDRIAAGTYM
HHHHCCCCCCCHHHHHHHHHHCCCCEECCCCCEEEEEEHHHHCCCCCEECCHHHCCCEEE
VATAITGGEVTLTNVVPSHVEKTVNLLEKCGVQVVVGDRNISVSAKNRQLNSPGKIETNP
EEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEECCCEEEEEECCCCCCCCCCCCCCC
YPGFPTDMQPQFMALSCLLTGSTKITENIFEGRFKHVSELLKMGADISIEGNYAIVKGNS
CCCCCCCCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCC
ALSGTVVKASDLRAGAALTLAALAAEGVTIIENIDHIDRGYEDFDRDLNALGANMFRISN
CCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECC
HSDIKSDENA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA