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The map label for this gene is murG

Identifier: 188585930

GI number: 188585930

Start: 1377264

End: 1378367

Strand: Direct

Name: murG

Synonym: Nther_1304

Alternate gene names: 188585930

Gene position: 1377264-1378367 (Clockwise)

Preceding gene: 188585929

Following gene: 188585931

Centisome position: 43.51

GC content: 36.23

Gene sequence:

>1104_bases
ATGAAAGTATTGGTAACTGGTGGGGGCACGGGTGGTCATATCTACCCGGCCCTTGCTGTAATAAATGAACTCAAAGAGCG
CAATCAAATAGTTGACATACTTTATGTAGGCACCTCCAAAGGTATGGAGCAAGAAATAATACCTAATAGAGGTATTGATT
TTGCAGCTATTACAGTGAGAGGCCTTCAACGTAAGATTAATTTAGAACAGGTGTATTTTTTACGAGATTTTTTAAAAGGG
CTTTATCAATCTTACAGATTGATAAAAAATTTTACCCCTGATGTGGTAATTGGGACCGGTGGTTATGTTTGCGGTCCTGT
TCTTATGGCAGCCAGTTTAATGAAGATTCCTACAGTACTTCATGAACAAAACGTGATTCCAGGTATCACCAATAAATTTT
TGTCTAGATTTGCCGATTATACCTGTGTTAGCTTTCCAGAATCAAAAAACTATATGACAAAAGCAAAAAAAATTATTACA
ACAGGTAATCCTAGAGCTCAAGAAATAACCAGTCGAGATTTTTCTAGTGTGAATAAGCATCTGAACTTGAGATCTGATCT
TAAAACTTTACTGATTGTTAGCGGAAGTAGAGGGGCACAAAAAATAAATGAAACTATGATCAATATTATACCTGAACTTA
TTTCCAAATTTCCCATACAAATTATCTATGTAACGGGTAATAATTACTACGAATCAATTAGGTCCCAGATACTAGAATAT
GTAGATAACTCTTATCAAGATCGTCTTAAACTTCATGCATATCTATCTGATTTGCCGGCTGCCATCAGCTGTGCTGATTT
GGTTATAAGTAGGGCTGGAGCTACTACCCTTGCCGAACTTACAGCAGCCGAGACTCCTTCAATATTAATACCGTCACCAA
ATGTCACCAATGACCACCAAAGAGTAAATGCTAAAATTTTAGGAGAACGAGGGGCTGCTAAAGTTCTCACTGAAGACTCG
CTAAATGAACAAGAAGTTATTAAATCAATATCTTCTATTATTAATGATGAAGAGGTACTTTTTGATATGCAAAGAGCTAC
CAAAGAGATAAGTTATCCAACTGCGGCTACAGAAATATGTAAGATCTTAGAATCCTTAATCTGA

Upstream 100 bases:

>100_bases
CAATTGGAATCCTCCTTAATATTTCTAAACATAATCAAATTTAACAACTCGACAGTATTAATATAACACTAATGTGCAGT
ACCAAGTCAGGAGGTCTGTT

Downstream 100 bases:

>100_bases
CAAGTCCATTAGAAAAGGGACAAGCGTAATTAACACCAGTTAAATTTATTGCATATCATAAACCAAGATTCAAGATTAAG
GTTATGCAATTAATTGGGGG

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKVLVTGGGTGGHIYPALAVINELKERNQIVDILYVGTSKGMEQEIIPNRGIDFAAITVRGLQRKINLEQVYFLRDFLKG
LYQSYRLIKNFTPDVVIGTGGYVCGPVLMAASLMKIPTVLHEQNVIPGITNKFLSRFADYTCVSFPESKNYMTKAKKIIT
TGNPRAQEITSRDFSSVNKHLNLRSDLKTLLIVSGSRGAQKINETMINIIPELISKFPIQIIYVTGNNYYESIRSQILEY
VDNSYQDRLKLHAYLSDLPAAISCADLVISRAGATTLAELTAAETPSILIPSPNVTNDHQRVNAKILGERGAAKVLTEDS
LNEQEVIKSISSIINDEEVLFDMQRATKEISYPTAATEICKILESLI

Sequences:

>Translated_367_residues
MKVLVTGGGTGGHIYPALAVINELKERNQIVDILYVGTSKGMEQEIIPNRGIDFAAITVRGLQRKINLEQVYFLRDFLKG
LYQSYRLIKNFTPDVVIGTGGYVCGPVLMAASLMKIPTVLHEQNVIPGITNKFLSRFADYTCVSFPESKNYMTKAKKIIT
TGNPRAQEITSRDFSSVNKHLNLRSDLKTLLIVSGSRGAQKINETMINIIPELISKFPIQIIYVTGNNYYESIRSQILEY
VDNSYQDRLKLHAYLSDLPAAISCADLVISRAGATTLAELTAAETPSILIPSPNVTNDHQRVNAKILGERGAAKVLTEDS
LNEQEVIKSISSIINDEEVLFDMQRATKEISYPTAATEICKILESLI
>Mature_367_residues
MKVLVTGGGTGGHIYPALAVINELKERNQIVDILYVGTSKGMEQEIIPNRGIDFAAITVRGLQRKINLEQVYFLRDFLKG
LYQSYRLIKNFTPDVVIGTGGYVCGPVLMAASLMKIPTVLHEQNVIPGITNKFLSRFADYTCVSFPESKNYMTKAKKIIT
TGNPRAQEITSRDFSSVNKHLNLRSDLKTLLIVSGSRGAQKINETMINIIPELISKFPIQIIYVTGNNYYESIRSQILEY
VDNSYQDRLKLHAYLSDLPAAISCADLVISRAGATTLAELTAAETPSILIPSPNVTNDHQRVNAKILGERGAAKVLTEDS
LNEQEVIKSISSIINDEEVLFDMQRATKEISYPTAATEICKILESLI

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=371, Percent_Identity=31.266846361186, Blast_Score=171, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_NATTJ (B2A2H2)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917475.1
- ProteinModelPortal:   B2A2H2
- GeneID:   6315585
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1304
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 40663; Mature: 40663

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGGTGGHIYPALAVINELKERNQIVDILYVGTSKGMEQEIIPNRGIDFAAITVR
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCCCHHHHHH
GLQRKINLEQVYFLRDFLKGLYQSYRLIKNFTPDVVIGTGGYVCGPVLMAASLMKIPTVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HEQNVIPGITNKFLSRFADYTCVSFPESKNYMTKAKKIITTGNPRAQEITSRDFSSVNKH
HCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
LNLRSDLKTLLIVSGSRGAQKINETMINIIPELISKFPIQIIYVTGNNYYESIRSQILEY
CCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHH
VDNSYQDRLKLHAYLSDLPAAISCADLVISRAGATTLAELTAAETPSILIPSPNVTNDHQ
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCHH
RVNAKILGERGAAKVLTEDSLNEQEVIKSISSIINDEEVLFDMQRATKEISYPTAATEIC
HHHHHEECCCCCHHECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHH
KILESLI
HHHHHHC
>Mature Secondary Structure
MKVLVTGGGTGGHIYPALAVINELKERNQIVDILYVGTSKGMEQEIIPNRGIDFAAITVR
CEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHCCCCCCCCCHHHHHH
GLQRKINLEQVYFLRDFLKGLYQSYRLIKNFTPDVVIGTGGYVCGPVLMAASLMKIPTVL
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
HEQNVIPGITNKFLSRFADYTCVSFPESKNYMTKAKKIITTGNPRAQEITSRDFSSVNKH
HCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
LNLRSDLKTLLIVSGSRGAQKINETMINIIPELISKFPIQIIYVTGNNYYESIRSQILEY
CCCHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHH
VDNSYQDRLKLHAYLSDLPAAISCADLVISRAGATTLAELTAAETPSILIPSPNVTNDHQ
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCHH
RVNAKILGERGAAKVLTEDSLNEQEVIKSISSIINDEEVLFDMQRATKEISYPTAATEIC
HHHHHEECCCCCHHECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHH
KILESLI
HHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA