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The map label for this gene is asd [H]

Identifier: 188585899

GI number: 188585899

Start: 1342441

End: 1343448

Strand: Direct

Name: asd [H]

Synonym: Nther_1273

Alternate gene names: 188585899

Gene position: 1342441-1343448 (Clockwise)

Preceding gene: 188585898

Following gene: 188585900

Centisome position: 42.41

GC content: 38.0

Gene sequence:

>1008_bases
TTGTCTTTTAAATTAGGCGTTGTAGGTGCTACCGGTTTAGTTGGTGGCAAGATCTTGGAAGTTCTTGAAGAACGGAATAT
TACCCCTCAAGAATTGTATCTTTTGACAACAAAAAAGTCTGCTGGTTTGCCCCTGTACTTTAAAGGCACAAAAATATTTA
CCAGAGAAATAGATGTGGAGCTATTTTCGAAACTAGACTATATACTGTTTGCTGTAGGTGGAGACGTTAGTGAGGAATTC
GCTCCAAAAGCAGTCCAGGCTGGGGCAACTGTTATCGATAACAGTTCACGTTTCAGAATGGCTCCCCATGTACCATTAGT
GGTTCCTGAAGTCAATCCCGAAACAGCTAAGGAGCATCAAGGAATTATTGCAAACCCAAACTGTTCAACTATCCAGTTGG
TGGTACCTCTCAAATATATAGACGATGAATTTGGTGTTAAAAGGGTGATTGTTAGTACGTATCAAGCCGTGTCGGGTTCA
GGCAAAGCAGCCATGAAAGAATTGAGAAAAAACGCCGCATTGCAGTTGGCAGGCTATTACGAAGATACTGAGAGAAAGGC
ATATCCCAAGAATATTGAGTTTAACTGTCTACCTCATGTAGATGACTTTACTGAATCAGGTTTGACAAAAGAAGAACTAA
AAATGATTAACGAAACTCGCAAAATTATTTCACCGAATATCAAAATATCACCTACTTGTGTTAGAGTTCCTGTAGTAAAT
GGTCATAGTGAAGCAGTTACTATTGAAACTGAAGAAAATAATATCAACCCAGAAAAGGTGAGAGAGGTGTTAAAAACAGG
GGCAGGAATTGTAGTTAACGATAATTTAGGTGAAAATGATTATCCAACTGCTATAGATTGTGACGATTCTGATCAAATTT
ATGTAGGACGGATTAGAAAAGATCCTACATTAACCAATGGAATCAATTTATGGATTGTAGCAGATAATCTTCGAAAAGGG
GCTGCTACTAATGCAGTACAAATCTTAGAATATTTATTGCAAACTTGA

Upstream 100 bases:

>100_bases
GGGGTATTTTAGAATTGCCCTGACGGTGACAAAGGACAGACTAAAAACAGCTATGGAAAAAATATGTGAGTATTTTTCTT
AATTAAAGGGGAGAGGATAA

Downstream 100 bases:

>100_bases
TATTATTAGTAGGGCTGCATTTTTGCAGCCCTTTTTTTGACTAAACCCTTGATATTTGCTAGCAATTATTATTAAATGAA
AGGGAGAAAATAATTAGCTT

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSFKLGVVGATGLVGGKILEVLEERNITPQELYLLTTKKSAGLPLYFKGTKIFTREIDVELFSKLDYILFAVGGDVSEEF
APKAVQAGATVIDNSSRFRMAPHVPLVVPEVNPETAKEHQGIIANPNCSTIQLVVPLKYIDDEFGVKRVIVSTYQAVSGS
GKAAMKELRKNAALQLAGYYEDTERKAYPKNIEFNCLPHVDDFTESGLTKEELKMINETRKIISPNIKISPTCVRVPVVN
GHSEAVTIETEENNINPEKVREVLKTGAGIVVNDNLGENDYPTAIDCDDSDQIYVGRIRKDPTLTNGINLWIVADNLRKG
AATNAVQILEYLLQT

Sequences:

>Translated_335_residues
MSFKLGVVGATGLVGGKILEVLEERNITPQELYLLTTKKSAGLPLYFKGTKIFTREIDVELFSKLDYILFAVGGDVSEEF
APKAVQAGATVIDNSSRFRMAPHVPLVVPEVNPETAKEHQGIIANPNCSTIQLVVPLKYIDDEFGVKRVIVSTYQAVSGS
GKAAMKELRKNAALQLAGYYEDTERKAYPKNIEFNCLPHVDDFTESGLTKEELKMINETRKIISPNIKISPTCVRVPVVN
GHSEAVTIETEENNINPEKVREVLKTGAGIVVNDNLGENDYPTAIDCDDSDQIYVGRIRKDPTLTNGINLWIVADNLRKG
AATNAVQILEYLLQT
>Mature_334_residues
SFKLGVVGATGLVGGKILEVLEERNITPQELYLLTTKKSAGLPLYFKGTKIFTREIDVELFSKLDYILFAVGGDVSEEFA
PKAVQAGATVIDNSSRFRMAPHVPLVVPEVNPETAKEHQGIIANPNCSTIQLVVPLKYIDDEFGVKRVIVSTYQAVSGSG
KAAMKELRKNAALQLAGYYEDTERKAYPKNIEFNCLPHVDDFTESGLTKEELKMINETRKIISPNIKISPTCVRVPVVNG
HSEAVTIETEENNINPEKVREVLKTGAGIVVNDNLGENDYPTAIDCDDSDQIYVGRIRKDPTLTNGINLWIVADNLRKGA
ATNAVQILEYLLQT

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=336, Percent_Identity=33.9285714285714, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1789841, Length=365, Percent_Identity=26.3013698630137, Blast_Score=88, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320362, Length=390, Percent_Identity=28.7179487179487, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36882; Mature: 36750

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKLGVVGATGLVGGKILEVLEERNITPQELYLLTTKKSAGLPLYFKGTKIFTREIDVE
CCEEEEEEECCHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCEEEEECCEEEEEECCHH
LFSKLDYILFAVGGDVSEEFAPKAVQAGATVIDNSSRFRMAPHVPLVVPEVNPETAKEHQ
HHHCCCEEEEEECCCCCHHHCCHHHHCCCEEEECCCCEEECCCCCEEEECCCCHHHHHCC
GIIANPNCSTIQLVVPLKYIDDEFGVKRVIVSTYQAVSGSGKAAMKELRKNAALQLAGYY
CEEECCCCCEEEEEEEEEECCCHHCHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEEECE
EDTERKAYPKNIEFNCLPHVDDFTESGLTKEELKMINETRKIISPNIKISPTCVRVPVVN
ECCCCCCCCCCCCEEECCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEECCEEEEEEEEC
GHSEAVTIETEENNINPEKVREVLKTGAGIVVNDNLGENDYPTAIDCDDSDQIYVGRIRK
CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCCEEEEEEEC
DPTLTNGINLWIVADNLRKGAATNAVQILEYLLQT
CCCEECCEEEEEEECCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SFKLGVVGATGLVGGKILEVLEERNITPQELYLLTTKKSAGLPLYFKGTKIFTREIDVE
CEEEEEEECCHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCEEEEECCEEEEEECCHH
LFSKLDYILFAVGGDVSEEFAPKAVQAGATVIDNSSRFRMAPHVPLVVPEVNPETAKEHQ
HHHCCCEEEEEECCCCCHHHCCHHHHCCCEEEECCCCEEECCCCCEEEECCCCHHHHHCC
GIIANPNCSTIQLVVPLKYIDDEFGVKRVIVSTYQAVSGSGKAAMKELRKNAALQLAGYY
CEEECCCCCEEEEEEEEEECCCHHCHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEEEECE
EDTERKAYPKNIEFNCLPHVDDFTESGLTKEELKMINETRKIISPNIKISPTCVRVPVVN
ECCCCCCCCCCCCEEECCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEECCEEEEEEEEC
GHSEAVTIETEENNINPEKVREVLKTGAGIVVNDNLGENDYPTAIDCDDSDQIYVGRIRK
CCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEECCCCCCEEEEEEEC
DPTLTNGINLWIVADNLRKGAATNAVQILEYLLQT
CCCEECCEEEEEEECCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]