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The map label for this gene is cidA1 [H]

Identifier: 188585636

GI number: 188585636

Start: 1075809

End: 1076165

Strand: Direct

Name: cidA1 [H]

Synonym: Nther_1009

Alternate gene names: 188585636

Gene position: 1075809-1076165 (Clockwise)

Preceding gene: 188585635

Following gene: 188585637

Centisome position: 33.98

GC content: 32.77

Gene sequence:

>357_bases
ATGCTTGGTTTAACCATTCTAATAGGTTTTGCTTTTTTAGGCGAATTAATGTCTATCTATTTAAATTTACCGCTCCCCGG
TAATGTAATCGGACTGATCTTATTTATAGTTTCACTATTTTCGGGGATTATTAAATTAGACTGGGTAGAAACTATTTCTT
CAGTGATAGTCAAACACCTAGCACTGTTCTTTATACCAGTCGTAGTTGCAATCATCTCATTGTTCCCTCTTTTAAGAGAG
AACTTATTGGTGATTATTATAAGTCTTACTGTAAGTACAATTCTTGTTTTATTAGCTACTGGTATTACTGTCAAACTTGC
CATATCTAGTAAATTAAGCAAAAAAGGAGAGAACTGA

Upstream 100 bases:

>100_bases
TGCAGGGATTTTTATTACTAAATAGTAGAAATTAAAGGAGATTGAACCATAGCAGACGAATATAAAAGCAATTAGGAAGT
AGTTGAAGGGGGAAGAAAAA

Downstream 100 bases:

>100_bases
TATGGAATTTCTAAATCAGCCAATTTTTGGTGTAGGGATGACAATCATCCCGTATATGATTTTTGTGTTATTGAAACAAA
GAGTTCCAATGGTAAATCCT

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MLGLTILIGFAFLGELMSIYLNLPLPGNVIGLILFIVSLFSGIIKLDWVETISSVIVKHLALFFIPVVVAIISLFPLLRE
NLLVIIISLTVSTILVLLATGITVKLAISSKLSKKGEN

Sequences:

>Translated_118_residues
MLGLTILIGFAFLGELMSIYLNLPLPGNVIGLILFIVSLFSGIIKLDWVETISSVIVKHLALFFIPVVVAIISLFPLLRE
NLLVIIISLTVSTILVLLATGITVKLAISSKLSKKGEN
>Mature_118_residues
MLGLTILIGFAFLGELMSIYLNLPLPGNVIGLILFIVSLFSGIIKLDWVETISSVIVKHLALFFIPVVVAIISLFPLLRE
NLLVIIISLTVSTILVLLATGITVKLAISSKLSKKGEN

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 12744; Mature: 12744

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGLTILIGFAFLGELMSIYLNLPLPGNVIGLILFIVSLFSGIIKLDWVETISSVIVKHL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFFIPVVVAIISLFPLLRENLLVIIISLTVSTILVLLATGITVKLAISSKLSKKGEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLGLTILIGFAFLGELMSIYLNLPLPGNVIGLILFIVSLFSGIIKLDWVETISSVIVKHL
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFFIPVVVAIISLFPLLRENLLVIIISLTVSTILVLLATGITVKLAISSKLSKKGEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]