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The map label for this gene is cbiJ [H]

Identifier: 188585564

GI number: 188585564

Start: 993881

End: 994666

Strand: Direct

Name: cbiJ [H]

Synonym: Nther_0936

Alternate gene names: 188585564

Gene position: 993881-994666 (Clockwise)

Preceding gene: 188585563

Following gene: 188585565

Centisome position: 31.4

GC content: 37.79

Gene sequence:

>786_bases
ATGATCTTAGTTTTGGGTGGAACCGATGATGGAATTAAAGTTGGCGAATTTTTAACTAAACAAGGTCATTCTGTTATGGT
CAGTGCCAGTACAGATTATGGTAAGAGTATCATTAGCAATTCGGGTCTGAGGGTTTTTCCAGATCCCCTCGGCATTTCCT
CGGGTGATTTTATAGACAAATTAAACCAGTATAATATTCAGGCTGTAGTGGATGCCACACATCCTTTCGCTACCTTTGTA
ACTAAAGGTGGTTTTCAAAGCTGCCGAGAAATAGGTATACCTTTTATTAGATTTGAAAGAGAAGCTGTTACCTTGCCTGA
TCCTGATCACAGCTTACTTAGACAAGTTGACAGTTTCCAGGAAGCTGCCGATTTAGCTCAGGAACTAGTTCTAGAACTGG
ACGATAAGGTTTTTTTAACTATTGGAACTAACAAAATAGATTATTTTACTTCAAGGATTTCCCAAGACAAGTTAATAGTG
CGAGTATTACCGATGGAAAGCAGTATAACTAACTGCCTTTGTCATGGTTTAAAACCCGACAACATTGTGGCCCTCAAAGG
TCCGTGGAGCTATTCCCTAAACAAGGAATTATTTCGCTCTTATAATACCAAGGTTTTACTTACAAAGGAGAGCGGTGAAA
GCAGTGGCCTACTAAATAAAATACAGGCTGCTCTGGACTTAAATATGAATGTCATTTTAATTAAGCGCCCTTACTATCCT
GAAATAACAACTACTTCCAATCTGTTAGAGCTTGAAAATTATTTATCTGCAAAATTATTCAATTAG

Upstream 100 bases:

>100_bases
TCACAAACTGTGATATTGATATGAGTACAACTGTCGTAATTGGTAATGACCAAAGTTATGTTAAATTCGAAAAGATGATT
ACTCCAAGGGGTTATCAATT

Downstream 100 bases:

>100_bases
ATTGAGGGGAAGGGGAATTTAAGATGGGAAAACTTGTACTTATCACTGGTGGTTCTGCTTCGGGGAAAAGTTACTATGCA
GAACAATTGGCTTCCCAATT

Product: precorrin-6x reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MILVLGGTDDGIKVGEFLTKQGHSVMVSASTDYGKSIISNSGLRVFPDPLGISSGDFIDKLNQYNIQAVVDATHPFATFV
TKGGFQSCREIGIPFIRFEREAVTLPDPDHSLLRQVDSFQEAADLAQELVLELDDKVFLTIGTNKIDYFTSRISQDKLIV
RVLPMESSITNCLCHGLKPDNIVALKGPWSYSLNKELFRSYNTKVLLTKESGESSGLLNKIQAALDLNMNVILIKRPYYP
EITTTSNLLELENYLSAKLFN

Sequences:

>Translated_261_residues
MILVLGGTDDGIKVGEFLTKQGHSVMVSASTDYGKSIISNSGLRVFPDPLGISSGDFIDKLNQYNIQAVVDATHPFATFV
TKGGFQSCREIGIPFIRFEREAVTLPDPDHSLLRQVDSFQEAADLAQELVLELDDKVFLTIGTNKIDYFTSRISQDKLIV
RVLPMESSITNCLCHGLKPDNIVALKGPWSYSLNKELFRSYNTKVLLTKESGESSGLLNKIQAALDLNMNVILIKRPYYP
EITTTSNLLELENYLSAKLFN
>Mature_261_residues
MILVLGGTDDGIKVGEFLTKQGHSVMVSASTDYGKSIISNSGLRVFPDPLGISSGDFIDKLNQYNIQAVVDATHPFATFV
TKGGFQSCREIGIPFIRFEREAVTLPDPDHSLLRQVDSFQEAADLAQELVLELDDKVFLTIGTNKIDYFTSRISQDKLIV
RVLPMESSITNCLCHGLKPDNIVALKGPWSYSLNKELFRSYNTKVLLTKESGESSGLLNKIQAALDLNMNVILIKRPYYP
EITTTSNLLELENYLSAKLFN

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 28972; Mature: 28972

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLGGTDDGIKVGEFLTKQGHSVMVSASTDYGKSIISNSGLRVFPDPLGISSGDFIDK
CEEEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHCCCCCEECCCCCCCCCCHHHHH
LNQYNIQAVVDATHPFATFVTKGGFQSCREIGIPFIRFEREAVTLPDPDHSLLRQVDSFQ
HCCCCEEEEEECCCCHHHHHCCCCHHHHHHHCCCEEEEECCEEECCCCCHHHHHHHHHHH
EAADLAQELVLELDDKVFLTIGTNKIDYFTSRISQDKLIVRVLPMESSITNCLCHGLKPD
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCC
NIVALKGPWSYSLNKELFRSYNTKVLLTKESGESSGLLNKIQAALDLNMNVILIKRPYYP
CEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
EITTTSNLLELENYLSAKLFN
CCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILVLGGTDDGIKVGEFLTKQGHSVMVSASTDYGKSIISNSGLRVFPDPLGISSGDFIDK
CEEEEECCCCCCCHHHHHHCCCCEEEEEECCCHHHHHHCCCCCEECCCCCCCCCCHHHHH
LNQYNIQAVVDATHPFATFVTKGGFQSCREIGIPFIRFEREAVTLPDPDHSLLRQVDSFQ
HCCCCEEEEEECCCCHHHHHCCCCHHHHHHHCCCEEEEECCEEECCCCCHHHHHHHHHHH
EAADLAQELVLELDDKVFLTIGTNKIDYFTSRISQDKLIVRVLPMESSITNCLCHGLKPD
HHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCC
NIVALKGPWSYSLNKELFRSYNTKVLLTKESGESSGLLNKIQAALDLNMNVILIKRPYYP
CEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
EITTTSNLLELENYLSAKLFN
CCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]