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The map label for this gene is cobU [H]

Identifier: 188585565

GI number: 188585565

Start: 994690

End: 995271

Strand: Direct

Name: cobU [H]

Synonym: Nther_0937

Alternate gene names: 188585565

Gene position: 994690-995271 (Clockwise)

Preceding gene: 188585564

Following gene: 188585566

Centisome position: 31.42

GC content: 40.21

Gene sequence:

>582_bases
ATGGGAAAACTTGTACTTATCACTGGTGGTTCTGCTTCGGGGAAAAGTTACTATGCAGAACAATTGGCTTCCCAATTGGA
ATCAAAACATAGTGAGCTTGACGGAGTCATTTATGTGGCCACCTCTCGTGTGGAGGACCAAGAAATGAGCCAACGAGTTT
TAAAACATAAGAATCGCCGTCCTGAACACTGGGACACGGTGGTAGCACCTAAACTCAACTGGGAAGACATCAATCAAATT
GTTCAGAAAAACCAGATTGTTTTAATAGATTCTATCTCTATGTATCTCTCAAATAACTTACTTGATTTTATTGGTTCAAA
TGATCCGGATAATTTAGATGCTAGCTGTATGGAAAAGTTCATCTACCAACAGAAAGCTCAAATGGACGAGCTCTGTAATT
TGTTTTTGCAAGGAACAGCAACTGTAATAACAGTGAGTGATGAGGTGGGTTGGGGATTGGTGCCAGCTCATAAAATGGGG
AGATTGTATCGTGATTTGGTGGGAAGGATGAATCAAATATTGGCTCAAAAAGCTCAAGAGGTTTCCTTAGTGGTATCTGG
TATTCCCACGAGAATTAAATGA

Upstream 100 bases:

>100_bases
CTTACTATCCTGAAATAACAACTACTTCCAATCTGTTAGAGCTTGAAAATTATTTATCTGCAAAATTATTCAATTAGATT
GAGGGGAAGGGGAATTTAAG

Downstream 100 bases:

>100_bases
GAAATTAACTAATTTGAAGGGAGAGTTTTTTATGCTAAGTTTGGATCACAGAGAATTGGTGAAAATTGCATTGTTAATAG
CTTTATCAATGATTGGTTCC

Product: Adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MGKLVLITGGSASGKSYYAEQLASQLESKHSELDGVIYVATSRVEDQEMSQRVLKHKNRRPEHWDTVVAPKLNWEDINQI
VQKNQIVLIDSISMYLSNNLLDFIGSNDPDNLDASCMEKFIYQQKAQMDELCNLFLQGTATVITVSDEVGWGLVPAHKMG
RLYRDLVGRMNQILAQKAQEVSLVVSGIPTRIK

Sequences:

>Translated_193_residues
MGKLVLITGGSASGKSYYAEQLASQLESKHSELDGVIYVATSRVEDQEMSQRVLKHKNRRPEHWDTVVAPKLNWEDINQI
VQKNQIVLIDSISMYLSNNLLDFIGSNDPDNLDASCMEKFIYQQKAQMDELCNLFLQGTATVITVSDEVGWGLVPAHKMG
RLYRDLVGRMNQILAQKAQEVSLVVSGIPTRIK
>Mature_192_residues
GKLVLITGGSASGKSYYAEQLASQLESKHSELDGVIYVATSRVEDQEMSQRVLKHKNRRPEHWDTVVAPKLNWEDINQIV
QKNQIVLIDSISMYLSNNLLDFIGSNDPDNLDASCMEKFIYQQKAQMDELCNLFLQGTATVITVSDEVGWGLVPAHKMGR
LYRDLVGRMNQILAQKAQEVSLVVSGIPTRIK

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=194, Percent_Identity=38.1443298969072, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21667; Mature: 21536

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLVLITGGSASGKSYYAEQLASQLESKHSELDGVIYVATSRVEDQEMSQRVLKHKNRR
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCC
PEHWDTVVAPKLNWEDINQIVQKNQIVLIDSISMYLSNNLLDFIGSNDPDNLDASCMEKF
CCCCCCEECCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IYQQKAQMDELCNLFLQGTATVITVSDEVGWGLVPAHKMGRLYRDLVGRMNQILAQKAQE
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VSLVVSGIPTRIK
HHHHHCCCCCCCC
>Mature Secondary Structure 
GKLVLITGGSASGKSYYAEQLASQLESKHSELDGVIYVATSRVEDQEMSQRVLKHKNRR
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCC
PEHWDTVVAPKLNWEDINQIVQKNQIVLIDSISMYLSNNLLDFIGSNDPDNLDASCMEKF
CCCCCCEECCCCCHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IYQQKAQMDELCNLFLQGTATVITVSDEVGWGLVPAHKMGRLYRDLVGRMNQILAQKAQE
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VSLVVSGIPTRIK
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]