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The map label for this gene is cbiT [H]

Identifier: 188585559

GI number: 188585559

Start: 988963

End: 990234

Strand: Direct

Name: cbiT [H]

Synonym: Nther_0931

Alternate gene names: 188585559

Gene position: 988963-990234 (Clockwise)

Preceding gene: 188585558

Following gene: 188585560

Centisome position: 31.24

GC content: 35.85

Gene sequence:

>1272_bases
ATGGGAAAGATTATCATAGTGGGAATTGGACCAGGAAGTAAATCTTACTTAACAGAACAGGGAAAAAATTATATTTTAAA
TGCAAGCATTCTTGTGGGATCTCAACCTGCTCTTAAATTGTCCCGAGTATTGGGCGCACAACCTAATAAGACTTATGATT
ATTCTCTTGGGATGGATTCAATTTTAGCAAAAATAGATTCGTGCCTTCAAGAAGATAGAACTGTCACAGTTCTAGTATCG
GGAGACCCGGGATATTACAGCCTGTGTTCATTGATTAAAAATAAATTTTCCCAGGATAAAATTAAAATTGTCCCAGGAAT
CAGTTCTCTGCAGTTAGGTCTCTCTAAAATTCAAGAAAACTGGAATGATGTAGACAGCATTAGTCTTCACGGTAGAAAAA
ATAATCTGGAAAATTGTCTTTTGTTAATGAAATCTTGTGACAAGTTAGCAATCTTACTAGGAGGAGATGTTGATACCCAT
TTGTTCGGTGAGTATATATGTTTAAATGATTCTAATTTTAAAAAAAGAAAAGTAACTGTGTTGGCTAATCTTTCATGGGA
TAGTGAACAAGTTTTTGAAACTACCATTGAACAATTAAGCAATTATCCTCCGTATGAAAACTGCATTCTATTTACTAACC
GTGAGAGTGGGGAAGCAGGTGACTGTAACAGTACGAAAGTTAGTTTTTCGGATAAAGAGATCATAAAAAGAAATGTACCC
AGGACCAAAGAAGAAATTAGGGCAGTCCTTGTCTCTAAAATGAATTTATATCGAGGAGCTGTTGTTTGGGATATTGGTGC
TGGTACTGGGGCAATATCATTAGAATGTTCTAGTATGGTTGGCCCTCAAGGAAAAGTGTGTGCTGTAGAACGTTCAACTG
AAGCTCTGGAAGTGATTAAAGAAAATAAATCTAAATTCCAAAGAAATAATATTGAAATCGTGGCAGGTGAAGCCCCTGGA
GTTTTAGGTGAACTTCCACCCCCTGACAGAGTTATAGTTGGAGGAAGTAGTGGTCAATTAACTCCTATTTTAAACTATCT
GAATCAACTGGAAAGTTTTACAGGTCCAGTAGTAATCTCTACAGTTGCCCTGGAAAGCTTTTATACTGCCTGGGAATTTT
TCGAAAATCAAAGGGGTTGGGAGCTAGAAATTAAACAAATTCAGGTTAATTATATGAAGACTTTGAATGATAATATATCG
ATTTGGGCAGGGCAAAACCCTATTTCAATATTGATTGCAACAAAATTCTCTAATAGTAGTACCATTTTGTAG

Upstream 100 bases:

>100_bases
CCGACCATCAAGTAGGGGTTTTATTAACCAATAGGCCCGGTAAGATCATTGCATGGGGTAATGGAGCAAAAGATATATGC
TATAGCAAAGGGTGGGATGT

Downstream 100 bases:

>100_bases
TAGTACCACCTTGAAAAACCTTTCAAAAAAGGGGCTGAGGATATGTATAACACGAGGAAACTAAAATCGGGGAAACTATA
TGCTATAGGAGTAGGTCCGG

Product: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MGKIIIVGIGPGSKSYLTEQGKNYILNASILVGSQPALKLSRVLGAQPNKTYDYSLGMDSILAKIDSCLQEDRTVTVLVS
GDPGYYSLCSLIKNKFSQDKIKIVPGISSLQLGLSKIQENWNDVDSISLHGRKNNLENCLLLMKSCDKLAILLGGDVDTH
LFGEYICLNDSNFKKRKVTVLANLSWDSEQVFETTIEQLSNYPPYENCILFTNRESGEAGDCNSTKVSFSDKEIIKRNVP
RTKEEIRAVLVSKMNLYRGAVVWDIGAGTGAISLECSSMVGPQGKVCAVERSTEALEVIKENKSKFQRNNIEIVAGEAPG
VLGELPPPDRVIVGGSSGQLTPILNYLNQLESFTGPVVISTVALESFYTAWEFFENQRGWELEIKQIQVNYMKTLNDNIS
IWAGQNPISILIATKFSNSSTIL

Sequences:

>Translated_423_residues
MGKIIIVGIGPGSKSYLTEQGKNYILNASILVGSQPALKLSRVLGAQPNKTYDYSLGMDSILAKIDSCLQEDRTVTVLVS
GDPGYYSLCSLIKNKFSQDKIKIVPGISSLQLGLSKIQENWNDVDSISLHGRKNNLENCLLLMKSCDKLAILLGGDVDTH
LFGEYICLNDSNFKKRKVTVLANLSWDSEQVFETTIEQLSNYPPYENCILFTNRESGEAGDCNSTKVSFSDKEIIKRNVP
RTKEEIRAVLVSKMNLYRGAVVWDIGAGTGAISLECSSMVGPQGKVCAVERSTEALEVIKENKSKFQRNNIEIVAGEAPG
VLGELPPPDRVIVGGSSGQLTPILNYLNQLESFTGPVVISTVALESFYTAWEFFENQRGWELEIKQIQVNYMKTLNDNIS
IWAGQNPISILIATKFSNSSTIL
>Mature_422_residues
GKIIIVGIGPGSKSYLTEQGKNYILNASILVGSQPALKLSRVLGAQPNKTYDYSLGMDSILAKIDSCLQEDRTVTVLVSG
DPGYYSLCSLIKNKFSQDKIKIVPGISSLQLGLSKIQENWNDVDSISLHGRKNNLENCLLLMKSCDKLAILLGGDVDTHL
FGEYICLNDSNFKKRKVTVLANLSWDSEQVFETTIEQLSNYPPYENCILFTNRESGEAGDCNSTKVSFSDKEIIKRNVPR
TKEEIRAVLVSKMNLYRGAVVWDIGAGTGAISLECSSMVGPQGKVCAVERSTEALEVIKENKSKFQRNNIEIVAGEAPGV
LGELPPPDRVIVGGSSGQLTPILNYLNQLESFTGPVVISTVALESFYTAWEFFENQRGWELEIKQIQVNYMKTLNDNISI
WAGQNPISILIATKFSNSSTIL

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12 [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014008
- InterPro:   IPR000241 [H]

Pfam domain/function: PF01170 UPF0020 [H]

EC number: NA

Molecular weight: Translated: 46541; Mature: 46410

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIIIVGIGPGSKSYLTEQGKNYILNASILVGSQPALKLSRVLGAQPNKTYDYSLGMDS
CCCEEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCEEECCCHHH
ILAKIDSCLQEDRTVTVLVSGDPGYYSLCSLIKNKFSQDKIKIVPGISSLQLGLSKIQEN
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHC
WNDVDSISLHGRKNNLENCLLLMKSCDKLAILLGGDVDTHLFGEYICLNDSNFKKRKVTV
CCCCCCEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCEEEECCCCCCEEEEEE
LANLSWDSEQVFETTIEQLSNYPPYENCILFTNRESGEAGDCNSTKVSFSDKEIIKRNVP
EEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEECCHHHHHHCCCC
RTKEEIRAVLVSKMNLYRGAVVWDIGAGTGAISLECSSMVGPQGKVCAVERSTEALEVIK
CCHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEHHCCCCCCCEEEEECCHHHHHHHH
ENKSKFQRNNIEIVAGEAPGVLGELPPPDRVIVGGSSGQLTPILNYLNQLESFTGPVVIS
HHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEH
TVALESFYTAWEFFENQRGWELEIKQIQVNYMKTLNDNISIWAGQNPISILIATKFSNSS
HHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCCEEEEECCCCEEEEEEEEECCCC
TIL
CCC
>Mature Secondary Structure 
GKIIIVGIGPGSKSYLTEQGKNYILNASILVGSQPALKLSRVLGAQPNKTYDYSLGMDS
CCEEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCEEECCCHHH
ILAKIDSCLQEDRTVTVLVSGDPGYYSLCSLIKNKFSQDKIKIVPGISSLQLGLSKIQEN
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHC
WNDVDSISLHGRKNNLENCLLLMKSCDKLAILLGGDVDTHLFGEYICLNDSNFKKRKVTV
CCCCCCEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHCCCEEEECCCCCCEEEEEE
LANLSWDSEQVFETTIEQLSNYPPYENCILFTNRESGEAGDCNSTKVSFSDKEIIKRNVP
EEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEECCHHHHHHCCCC
RTKEEIRAVLVSKMNLYRGAVVWDIGAGTGAISLECSSMVGPQGKVCAVERSTEALEVIK
CCHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEHHCCCCCCCEEEEECCHHHHHHHH
ENKSKFQRNNIEIVAGEAPGVLGELPPPDRVIVGGSSGQLTPILNYLNQLESFTGPVVIS
HHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEH
TVALESFYTAWEFFENQRGWELEIKQIQVNYMKTLNDNISIWAGQNPISILIATKFSNSS
HHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHHHHCCCCEEEEECCCCEEEEEEEEECCCC
TIL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792869 [H]