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The map label for this gene is cbiL [H]

Identifier: 188585560

GI number: 188585560

Start: 990277

End: 991149

Strand: Direct

Name: cbiL [H]

Synonym: Nther_0932

Alternate gene names: 188585560

Gene position: 990277-991149 (Clockwise)

Preceding gene: 188585559

Following gene: 188585561

Centisome position: 31.28

GC content: 36.66

Gene sequence:

>873_bases
ATGTATAACACGAGGAAACTAAAATCGGGGAAACTATATGCTATAGGAGTAGGTCCGGGGGATCCGGAATTACTAACCTT
AAAAGCTGTGAGAGTTCTATCGAGTAGTGATATTATTATAGCTCCTAAGAGTCCAGGGCAGAAAAAAGGCTATGCCCAGA
GCATTGTTAAAGCAGCTTTTAAAAACTGGGAATGGGATGACAAATTACCTCCAGTGGAGACAGTAGAAGTTAGCATGAAT
TCGAGTGCGGATAGCAAAACTTTTACAATTAAAAACTCACTGCAAAGAAAAGTTCTTGAAAAACTGCTTGCAGGTCAAAA
TATATCTTTCATTACCCTGGGAGATCCTATGTTTTATAGTACCTATAGGCATTTAGCCCAATTAATTCAAGAATATAATC
AAACTAATCAAGCCGATCAAACCAAACAAACCGAGCTAATCGATCAAATCAATCAGACCAATTTGACCAATCAGATCAAT
GGGGCAAACTCGTTTAATTCACAATCAAATGATGCCCATATCCAGGTTGAAGTGATCCCAGGTATCTATTCCTTTAGTGC
CATTAGTGCTAAAATTGGTGGGATTCAACTTACCTTTGGGTCTGATAAAACAGTGATTGTTCCGGTAAAAAAAGATCAAG
ATTATCGAAATTACCTAAAAGATTTTGAAACTTTGGTGTTTTTAAAAGTTACCAGTAATTTTGACAAGCTAGTAAATCAA
ATCAAAGAATCCCAGAGAGTTGAAGAGGCCGTACTCGTTGAAAAGTTGGGTTTTCCCGATGAGAAATTATATCAAAATAT
CTTGGAAGTGGAACCTAGAAAAGTCAGTTATCTATCAACACTGATAGTCTCAAAAAATTTAGGAAGCAGGTGA

Upstream 100 bases:

>100_bases
AAACCCTATTTCAATATTGATTGCAACAAAATTCTCTAATAGTAGTACCATTTTGTAGTAGTACCACCTTGAAAAACCTT
TCAAAAAAGGGGCTGAGGAT

Downstream 100 bases:

>100_bases
TACTATGGACAGATCACAGCAGCCAAAAGTCTATTTTTTAGGAGCAGGTCCTGGTGACCCGGAACTTTTAACGAGGAAAG
GGGAAAAATTGCTGACTGAT

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MYNTRKLKSGKLYAIGVGPGDPELLTLKAVRVLSSSDIIIAPKSPGQKKGYAQSIVKAAFKNWEWDDKLPPVETVEVSMN
SSADSKTFTIKNSLQRKVLEKLLAGQNISFITLGDPMFYSTYRHLAQLIQEYNQTNQADQTKQTELIDQINQTNLTNQIN
GANSFNSQSNDAHIQVEVIPGIYSFSAISAKIGGIQLTFGSDKTVIVPVKKDQDYRNYLKDFETLVFLKVTSNFDKLVNQ
IKESQRVEEAVLVEKLGFPDEKLYQNILEVEPRKVSYLSTLIVSKNLGSR

Sequences:

>Translated_290_residues
MYNTRKLKSGKLYAIGVGPGDPELLTLKAVRVLSSSDIIIAPKSPGQKKGYAQSIVKAAFKNWEWDDKLPPVETVEVSMN
SSADSKTFTIKNSLQRKVLEKLLAGQNISFITLGDPMFYSTYRHLAQLIQEYNQTNQADQTKQTELIDQINQTNLTNQIN
GANSFNSQSNDAHIQVEVIPGIYSFSAISAKIGGIQLTFGSDKTVIVPVKKDQDYRNYLKDFETLVFLKVTSNFDKLVNQ
IKESQRVEEAVLVEKLGFPDEKLYQNILEVEPRKVSYLSTLIVSKNLGSR
>Mature_290_residues
MYNTRKLKSGKLYAIGVGPGDPELLTLKAVRVLSSSDIIIAPKSPGQKKGYAQSIVKAAFKNWEWDDKLPPVETVEVSMN
SSADSKTFTIKNSLQRKVLEKLLAGQNISFITLGDPMFYSTYRHLAQLIQEYNQTNQADQTKQTELIDQINQTNLTNQIN
GANSFNSQSNDAHIQVEVIPGIYSFSAISAKIGGIQLTFGSDKTVIVPVKKDQDYRNYLKDFETLVFLKVTSNFDKLVNQ
IKESQRVEEAVLVEKLGFPDEKLYQNILEVEPRKVSYLSTLIVSKNLGSR

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 32517; Mature: 32517

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNTRKLKSGKLYAIGVGPGDPELLTLKAVRVLSSSDIIIAPKSPGQKKGYAQSIVKAAF
CCCCCEECCCCEEEEEECCCCCCEEEHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHH
KNWEWDDKLPPVETVEVSMNSSADSKTFTIKNSLQRKVLEKLLAGQNISFITLGDPMFYS
HCCCCCCCCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
TYRHLAQLIQEYNQTNQADQTKQTELIDQINQTNLTNQINGANSFNSQSNDAHIQVEVIP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GIYSFSAISAKIGGIQLTFGSDKTVIVPVKKDQDYRNYLKDFETLVFLKVTSNFDKLVNQ
CCHHHHHHHEEECCEEEEECCCCEEEEEECCCCHHHHHHHHHHHEEEEEECCCHHHHHHH
IKESQRVEEAVLVEKLGFPDEKLYQNILEVEPRKVSYLSTLIVSKNLGSR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYNTRKLKSGKLYAIGVGPGDPELLTLKAVRVLSSSDIIIAPKSPGQKKGYAQSIVKAAF
CCCCCEECCCCEEEEEECCCCCCEEEHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHH
KNWEWDDKLPPVETVEVSMNSSADSKTFTIKNSLQRKVLEKLLAGQNISFITLGDPMFYS
HCCCCCCCCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
TYRHLAQLIQEYNQTNQADQTKQTELIDQINQTNLTNQINGANSFNSQSNDAHIQVEVIP
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GIYSFSAISAKIGGIQLTFGSDKTVIVPVKKDQDYRNYLKDFETLVFLKVTSNFDKLVNQ
CCHHHHHHHEEECCEEEEECCCCEEEEEECCCCHHHHHHHHHHHEEEEEECCCHHHHHHH
IKESQRVEEAVLVEKLGFPDEKLYQNILEVEPRKVSYLSTLIVSKNLGSR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]