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The map label for this gene is cobB [H]

Identifier: 188585554

GI number: 188585554

Start: 983993

End: 985441

Strand: Direct

Name: cobB [H]

Synonym: Nther_0926

Alternate gene names: 188585554

Gene position: 983993-985441 (Clockwise)

Preceding gene: 188585548

Following gene: 188585557

Centisome position: 31.08

GC content: 38.23

Gene sequence:

>1449_bases
GTGATTCTTGTGAATAGAAAAAGGATAGTCGTTGCCGGGACAAATAGTGGAAGCGGCAAAACTACTGTTACAATGGCATT
ATTGGCAGCGTTAAGAAATCAAGGGCAGTCAGTACAAGGGTTTAAGGTTGGCCCTGATTACATAGATCCCAGCTTCCATA
CTACTATCACGGGAAGACCAGCTAGAAATCTTGATACATGGATGATGTCACCGAATATTATGAAGGAAATATTTCAGCGT
GGTTCAGAAAAAGCGGATATTTCAATAATTGAAGGTGTAATGGGCCTATACGATGGTAAATCGGGTAAAGACGACCGGGC
CAGTACTGCAGAAATCGCTAAAAAACTTGATGCACCAGTGATTTTAGTTGTTAATGCCAAAAGCCAGGCAAGAAGTGTAG
CTGCCTTAATTTATGGTTTCCAAAATTTTGACCCCGATGTAAAAGTTGCCGGAGTTATTTTAAACAAGGTTAGTTCTGAA
AACCATTATCGTTATCTAAAAGAAGCTGTAACATCCTTGGGTTCAGTAGAATTACTCGGTTATTTGCCTGATGAACCTGA
CATCGAATTACCGGAAAGGCATCTGGGATTAACCCCGGCAGAGGAAAGTCATGATTTACATCAGAAAGTTTCAAAACTGG
CAGATATGTTTAGTGAAAGGGTGGATATGAAAAAAATAAATCAATTGGCCACGGCTTATGAACAATGGCAGCCTGTTTCC
GAAACTTTTTATAATAACAAATTGGATTCAGTTAAAGAACATATGATCACTAACAAAACTACCAAAATTCCTGTGGCCAT
AGCTAAAGATCTTGCTTTCTCTTTTTATTATCAGGACAATTTAGAATGGCTTGAAGAACAAGGAGTTGAATGGGTACCAG
TCTCTCCTTTAAAAGATAAAGAGATTCCCGAATATGTGTGTGGATTATATCTAGGAGGAGGTTTCCCTGAATTATACGCT
TCTCAACTTTCATCCAATACTTCCTTCATGGATAATTTAAAAAATTTACATAAAAAGGGGTTGCCTATACTGGCAGAGTG
TGGTGGATTTATTTATTTATGTAATACTTTGCAGGACTTAAAAGGGGATAAGTATTCCCTGACAGGGTTGATACCTGGAC
AAGTAACAATGAATTCTAGGTTGATGGCCTTAGGTTATCGTGAAGCTCATGCCGTGAAAGATTCAATTCTACTTAAACAG
GGCGACAAAGTTAAGGGTCACGAATTTCGGTATTCACAATTCGAGGTAGAAATGAACGAAGAATTAGATGAAGACTCTTT
TCCCTATGCATACATTATCTCTGCAAGGAATAAAAGCAAACAAGCAGGTTACCTATCCGGCAACCTGCTGGCTAGTTACT
TGCATATACACCTGGCTTCAAATATTAATGCCGCAAAACGGTTGTTTAATAGTTTTCACGATTATTACAGGTTAAAGCAA
TTTCAATAA

Upstream 100 bases:

>100_bases
TTCATAGTATAATGGTCGAGAATGTTGAGAGTGTACTTACAATTCAGTATTCAATTTGTGTAATAGCACAAAACACAAGG
TTAAATAATTTACGGATGGG

Downstream 100 bases:

>100_bases
GGCATTGATAACGGAGGCCCCTATGGGGCTTCCTCCTTTATAACCGGAAATTGAAATATAAGGTAAGTCGGAGTTCATTA
ATGCATCTTTGGATTCTTTA

Product: cobyrinic acid a,c-diamide synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MILVNRKRIVVAGTNSGSGKTTVTMALLAALRNQGQSVQGFKVGPDYIDPSFHTTITGRPARNLDTWMMSPNIMKEIFQR
GSEKADISIIEGVMGLYDGKSGKDDRASTAEIAKKLDAPVILVVNAKSQARSVAALIYGFQNFDPDVKVAGVILNKVSSE
NHYRYLKEAVTSLGSVELLGYLPDEPDIELPERHLGLTPAEESHDLHQKVSKLADMFSERVDMKKINQLATAYEQWQPVS
ETFYNNKLDSVKEHMITNKTTKIPVAIAKDLAFSFYYQDNLEWLEEQGVEWVPVSPLKDKEIPEYVCGLYLGGGFPELYA
SQLSSNTSFMDNLKNLHKKGLPILAECGGFIYLCNTLQDLKGDKYSLTGLIPGQVTMNSRLMALGYREAHAVKDSILLKQ
GDKVKGHEFRYSQFEVEMNEELDEDSFPYAYIISARNKSKQAGYLSGNLLASYLHIHLASNINAAKRLFNSFHDYYRLKQ
FQ

Sequences:

>Translated_482_residues
MILVNRKRIVVAGTNSGSGKTTVTMALLAALRNQGQSVQGFKVGPDYIDPSFHTTITGRPARNLDTWMMSPNIMKEIFQR
GSEKADISIIEGVMGLYDGKSGKDDRASTAEIAKKLDAPVILVVNAKSQARSVAALIYGFQNFDPDVKVAGVILNKVSSE
NHYRYLKEAVTSLGSVELLGYLPDEPDIELPERHLGLTPAEESHDLHQKVSKLADMFSERVDMKKINQLATAYEQWQPVS
ETFYNNKLDSVKEHMITNKTTKIPVAIAKDLAFSFYYQDNLEWLEEQGVEWVPVSPLKDKEIPEYVCGLYLGGGFPELYA
SQLSSNTSFMDNLKNLHKKGLPILAECGGFIYLCNTLQDLKGDKYSLTGLIPGQVTMNSRLMALGYREAHAVKDSILLKQ
GDKVKGHEFRYSQFEVEMNEELDEDSFPYAYIISARNKSKQAGYLSGNLLASYLHIHLASNINAAKRLFNSFHDYYRLKQ
FQ
>Mature_482_residues
MILVNRKRIVVAGTNSGSGKTTVTMALLAALRNQGQSVQGFKVGPDYIDPSFHTTITGRPARNLDTWMMSPNIMKEIFQR
GSEKADISIIEGVMGLYDGKSGKDDRASTAEIAKKLDAPVILVVNAKSQARSVAALIYGFQNFDPDVKVAGVILNKVSSE
NHYRYLKEAVTSLGSVELLGYLPDEPDIELPERHLGLTPAEESHDLHQKVSKLADMFSERVDMKKINQLATAYEQWQPVS
ETFYNNKLDSVKEHMITNKTTKIPVAIAKDLAFSFYYQDNLEWLEEQGVEWVPVSPLKDKEIPEYVCGLYLGGGFPELYA
SQLSSNTSFMDNLKNLHKKGLPILAECGGFIYLCNTLQDLKGDKYSLTGLIPGQVTMNSRLMALGYREAHAVKDSILLKQ
GDKVKGHEFRYSQFEVEMNEELDEDSFPYAYIISARNKSKQAGYLSGNLLASYLHIHLASNINAAKRLFNSFHDYYRLKQ
FQ

Specific function: Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1797

COG function: function code H; Cobyrinic acid a,c-diamide synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR004484
- InterPro:   IPR017929
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: NA

Molecular weight: Translated: 54009; Mature: 54009

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVNRKRIVVAGTNSGSGKTTVTMALLAALRNQGQSVQGFKVGPDYIDPSFHTTITGRP
CEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEECCCC
ARNLDTWMMSPNIMKEIFQRGSEKADISIIEGVMGLYDGKSGKDDRASTAEIAKKLDAPV
CCCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCE
ILVVNAKSQARSVAALIYGFQNFDPDVKVAGVILNKVSSENHYRYLKEAVTSLGSVELLG
EEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEE
YLPDEPDIELPERHLGLTPAEESHDLHQKVSKLADMFSERVDMKKINQLATAYEQWQPVS
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ETFYNNKLDSVKEHMITNKTTKIPVAIAKDLAFSFYYQDNLEWLEEQGVEWVPVSPLKDK
HHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEECCCHHHHHHCCCCEEECCCCCCC
EIPEYVCGLYLGGGFPELYASQLSSNTSFMDNLKNLHKKGLPILAECGGFIYLCNTLQDL
CCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHH
KGDKYSLTGLIPGQVTMNSRLMALGYREAHAVKDSILLKQGDKVKGHEFRYSQFEVEMNE
CCCCEEEEEECCCCEEECCEEEEECCHHHHHHHHHHHHCCCCCCCCCCEECEEEEEEECC
ELDEDSFPYAYIISARNKSKQAGYLSGNLLASYLHIHLASNINAAKRLFNSFHDYYRLKQ
CCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
FQ
CC
>Mature Secondary Structure
MILVNRKRIVVAGTNSGSGKTTVTMALLAALRNQGQSVQGFKVGPDYIDPSFHTTITGRP
CEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEECCCC
ARNLDTWMMSPNIMKEIFQRGSEKADISIIEGVMGLYDGKSGKDDRASTAEIAKKLDAPV
CCCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCE
ILVVNAKSQARSVAALIYGFQNFDPDVKVAGVILNKVSSENHYRYLKEAVTSLGSVELLG
EEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEE
YLPDEPDIELPERHLGLTPAEESHDLHQKVSKLADMFSERVDMKKINQLATAYEQWQPVS
CCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
ETFYNNKLDSVKEHMITNKTTKIPVAIAKDLAFSFYYQDNLEWLEEQGVEWVPVSPLKDK
HHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHEEEEECCCHHHHHHCCCCEEECCCCCCC
EIPEYVCGLYLGGGFPELYASQLSSNTSFMDNLKNLHKKGLPILAECGGFIYLCNTLQDL
CCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEECCCCEEEEHHHHHHH
KGDKYSLTGLIPGQVTMNSRLMALGYREAHAVKDSILLKQGDKVKGHEFRYSQFEVEMNE
CCCCEEEEEECCCCEEECCEEEEECCHHHHHHHHHHHHCCCCCCCCCCEECEEEEEEECC
ELDEDSFPYAYIISARNKSKQAGYLSGNLLASYLHIHLASNINAAKRLFNSFHDYYRLKQ
CCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
FQ
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9742225 [H]