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The map label for this gene is dck [H]

Identifier: 188585314

GI number: 188585314

Start: 703505

End: 704131

Strand: Direct

Name: dck [H]

Synonym: Nther_0678

Alternate gene names: 188585314

Gene position: 703505-704131 (Clockwise)

Preceding gene: 188585313

Following gene: 188585315

Centisome position: 22.22

GC content: 34.29

Gene sequence:

>627_bases
ATGGGTCAAGTACCAATTGTAGTCGATGGTATGACGGGTTCGGGAAAAACTACCCTGGTGAATCATTTGGCAAATGAGTT
AAATTTGGAAGTTATGCCGGAAGAATTTCGTGATCCCTATAATCTCTTGTACAGATTTGCCGATGATGTTAAATGGTGTT
ATCCCATGCAGTTAAACTTTTTGATGACCAGGTATATACAGTATACGGTGGCATCTGAACATGAAAATTATATTCTGGAT
AGAAGTATTTATAGTGATCCGGTTTATGCAAAACTTTATTACAATATGGGTTATTTAAGTGAAAAACAGTACGACAATTA
CTTAAACTTTTATGATAGCCTGGAAGAAGATATCAAGGAACCAAAATGCATGATAATTTTAAATTGTTCCTTTGATGAGA
TTATGCGTCGGATAGTTGATAGAGGCAGATCTGACGAGTTGAAATTATCCAAAGAAGGTTACTGGTGGCCATTATACCAA
GCATATCAAGAACATGTTGATAAACTATTAACACAACAAGATCATATGTCAACAAAAGTGATTAGAATAGACACGGAAGA
TATTGACTTGGCCAAAAGAGATGAACAATTATTTGATATTTTAAATCTAGCAGAAACGGCTATTTAA

Upstream 100 bases:

>100_bases
TTCAAAAAAGATTATGATAAATACGATTCTGACTTCATAATTCAAGTAGCCCAAAAGTAAAAATTTAAGGGTTGAAATAA
ATGAAAGGGGGAGCATTTTC

Downstream 100 bases:

>100_bases
GGATTCTTTCATCCCAAAAAAAGATGAGAATGTTATAAGGAGGCCAAAAAAGTGAGTTTACCGGAATATGTAGGACCATG
TGCATTCGGAATCAAGATGG

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: dAK/dCK [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MGQVPIVVDGMTGSGKTTLVNHLANELNLEVMPEEFRDPYNLLYRFADDVKWCYPMQLNFLMTRYIQYTVASEHENYILD
RSIYSDPVYAKLYYNMGYLSEKQYDNYLNFYDSLEEDIKEPKCMIILNCSFDEIMRRIVDRGRSDELKLSKEGYWWPLYQ
AYQEHVDKLLTQQDHMSTKVIRIDTEDIDLAKRDEQLFDILNLAETAI

Sequences:

>Translated_208_residues
MGQVPIVVDGMTGSGKTTLVNHLANELNLEVMPEEFRDPYNLLYRFADDVKWCYPMQLNFLMTRYIQYTVASEHENYILD
RSIYSDPVYAKLYYNMGYLSEKQYDNYLNFYDSLEEDIKEPKCMIILNCSFDEIMRRIVDRGRSDELKLSKEGYWWPLYQ
AYQEHVDKLLTQQDHMSTKVIRIDTEDIDLAKRDEQLFDILNLAETAI
>Mature_207_residues
GQVPIVVDGMTGSGKTTLVNHLANELNLEVMPEEFRDPYNLLYRFADDVKWCYPMQLNFLMTRYIQYTVASEHENYILDR
SIYSDPVYAKLYYNMGYLSEKQYDNYLNFYDSLEEDIKEPKCMIILNCSFDEIMRRIVDRGRSDELKLSKEGYWWPLYQA
YQEHVDKLLTQQDHMSTKVIRIDTEDIDLAKRDEQLFDILNLAETAI

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the n

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.74; =2.7.1.76 [H]

Molecular weight: Translated: 24740; Mature: 24609

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQVPIVVDGMTGSGKTTLVNHLANELNLEVMPEEFRDPYNLLYRFADDVKWCYPMQLNF
CCCCCEEEECCCCCCHHHHHHHHHHHCCEEECCHHHCCHHHHHHHHHHCCCEECHHHHHH
LMTRYIQYTVASEHENYILDRSIYSDPVYAKLYYNMGYLSEKQYDNYLNFYDSLEEDIKE
HHHHHHHHHHHCCCCCEEECCHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
PKCMIILNCSFDEIMRRIVDRGRSDELKLSKEGYWWPLYQAYQEHVDKLLTQQDHMSTKV
CCEEEEEECCHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
IRIDTEDIDLAKRDEQLFDILNLAETAI
EEEECCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GQVPIVVDGMTGSGKTTLVNHLANELNLEVMPEEFRDPYNLLYRFADDVKWCYPMQLNF
CCCCEEEECCCCCCHHHHHHHHHHHCCEEECCHHHCCHHHHHHHHHHCCCEECHHHHHH
LMTRYIQYTVASEHENYILDRSIYSDPVYAKLYYNMGYLSEKQYDNYLNFYDSLEEDIKE
HHHHHHHHHHHCCCCCEEECCHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
PKCMIILNCSFDEIMRRIVDRGRSDELKLSKEGYWWPLYQAYQEHVDKLLTQQDHMSTKV
CCEEEEEECCHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEE
IRIDTEDIDLAKRDEQLFDILNLAETAI
EEEECCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]