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The map label for this gene is asd [H]

Identifier: 188585306

GI number: 188585306

Start: 693687

End: 694700

Strand: Reverse

Name: asd [H]

Synonym: Nther_0670

Alternate gene names: 188585306

Gene position: 694700-693687 (Counterclockwise)

Preceding gene: 188585308

Following gene: 188585305

Centisome position: 21.95

GC content: 36.09

Gene sequence:

>1014_bases
ATGGGTATAAATTTAGCAATTGTAGGAAGTACCGGGGCAGTCGGGCAAACCATCCTGGATATTTTAAGAGAAAATAATTT
GGATTTTTCTTTAAATAACTTAAAGCTCTTGGCATCTGAAAATTCGGCCGGTACTAAAATCACCTTTGGAGGTAAAGAAA
TTACCGTAGAAGCTGCCAATTCTTCCTCTTTTCACGATGTTGACATTGCCATTTTTAGTGCCGGTTCATCTGTTAGTAAA
AATTTGGCTCCTAAGGCTGTAGAATCTGGAGCCATTGTAATAGATAACAGTAGTGCTTTTAGGATGGATGATAAGGTACC
TCTGGTGGCAGCTGGAGTTAATTATGAATCTTTATATGAGCATGAGGGAATAATTGCCAATCCTAATTGCTCCACAATTC
AAATGGTCTGTGCATTAAAACCAATATTAGACCATGCCGGTATCAAGAGAATTGTAGTATCTACATATCAGTCCGTTTCT
GGTACAGGTTATCAAGCAATGAAGGAATTAACAGAACAAAGTCCAAAATATTTAAATAATGAAGCCATTGAAAAACAGAT
ATATCCCCATCAAATAGCCTTTAACATGCTTCCACACCTGGATTCTTTTGATGAAAATGGAGATACGAAAGAAGAATTGA
AAATGGTTAATGAAACTAAAAAAATCTTTCAAGATGAAAACATAGGAGTTACTGCTACTACTGTACGGGTGCCAGTTTTT
ATTGGACATTCTGAAGCGGTCAATATTGAGACAAAGTCTAAGCTTTCAGCTTGTGACGCAAGGCAATTACTAGAAAATTT
TTCGGAAGTAGAAGTTATTGATGACCCTTTTGAAGCAAAATATCCCACTCCTATTGAGATTGCCGGTAAAGACCAAGTCT
ATGTAGGTAGAATAAGAGAGGATCTTTCCATTGATAATGGGCTTAATTTGTGGGTAGTAGCTGATAACTTGAGACGAGGA
GCTGCCTTTAATGCTTTGTTATTAACTGAATATTTAGCTAAATATATAATTTAA

Upstream 100 bases:

>100_bases
TATCAATTAACCTGGATGTTTAAAATCCCAGGTATGGATATCCCGATTTTTTTATTTCGGTCTTTTTTAAATTAAATCGT
TAAAACGGGGGGGTGCACAG

Downstream 100 bases:

>100_bases
ATTCAAGGAGGATTATGATATGACATCAACTATTAAAATTGGCTTTCTAGGCTTTGGTACAGTGGGGACAGGTACTGTGG
AAGTTTTAACTGAAAATAAA

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MGINLAIVGSTGAVGQTILDILRENNLDFSLNNLKLLASENSAGTKITFGGKEITVEAANSSSFHDVDIAIFSAGSSVSK
NLAPKAVESGAIVIDNSSAFRMDDKVPLVAAGVNYESLYEHEGIIANPNCSTIQMVCALKPILDHAGIKRIVVSTYQSVS
GTGYQAMKELTEQSPKYLNNEAIEKQIYPHQIAFNMLPHLDSFDENGDTKEELKMVNETKKIFQDENIGVTATTVRVPVF
IGHSEAVNIETKSKLSACDARQLLENFSEVEVIDDPFEAKYPTPIEIAGKDQVYVGRIREDLSIDNGLNLWVVADNLRRG
AAFNALLLTEYLAKYII

Sequences:

>Translated_337_residues
MGINLAIVGSTGAVGQTILDILRENNLDFSLNNLKLLASENSAGTKITFGGKEITVEAANSSSFHDVDIAIFSAGSSVSK
NLAPKAVESGAIVIDNSSAFRMDDKVPLVAAGVNYESLYEHEGIIANPNCSTIQMVCALKPILDHAGIKRIVVSTYQSVS
GTGYQAMKELTEQSPKYLNNEAIEKQIYPHQIAFNMLPHLDSFDENGDTKEELKMVNETKKIFQDENIGVTATTVRVPVF
IGHSEAVNIETKSKLSACDARQLLENFSEVEVIDDPFEAKYPTPIEIAGKDQVYVGRIREDLSIDNGLNLWVVADNLRRG
AAFNALLLTEYLAKYII
>Mature_336_residues
GINLAIVGSTGAVGQTILDILRENNLDFSLNNLKLLASENSAGTKITFGGKEITVEAANSSSFHDVDIAIFSAGSSVSKN
LAPKAVESGAIVIDNSSAFRMDDKVPLVAAGVNYESLYEHEGIIANPNCSTIQMVCALKPILDHAGIKRIVVSTYQSVSG
TGYQAMKELTEQSPKYLNNEAIEKQIYPHQIAFNMLPHLDSFDENGDTKEELKMVNETKKIFQDENIGVTATTVRVPVFI
GHSEAVNIETKSKLSACDARQLLENFSEVEVIDDPFEAKYPTPIEIAGKDQVYVGRIREDLSIDNGLNLWVVADNLRRGA
AFNALLLTEYLAKYII

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=37.6854599406528, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=25.3521126760563, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320362, Length=376, Percent_Identity=26.063829787234, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36761; Mature: 36630

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGINLAIVGSTGAVGQTILDILRENNLDFSLNNLKLLASENSAGTKITFGGKEITVEAAN
CCEEEEEEECCCCHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCEEEECCEEEEEEECC
SSSFHDVDIAIFSAGSSVSKNLAPKAVESGAIVIDNSSAFRMDDKVPLVAAGVNYESLYE
CCCCCEEEEEEEECCCCHHCCCCCHHHCCCEEEEECCCCEEECCCCCEEEECCCHHHHHH
HEGIIANPNCSTIQMVCALKPILDHAGIKRIVVSTYQSVSGTGYQAMKELTEQSPKYLNN
CCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHCCC
EAIEKQIYPHQIAFNMLPHLDSFDENGDTKEELKMVNETKKIFQDENIGVTATTVRVPVF
HHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEE
IGHSEAVNIETKSKLSACDARQLLENFSEVEVIDDPFEAKYPTPIEIAGKDQVYVGRIRE
ECCCCEEEECHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEECCCCCEEEEHHHH
DLSIDNGLNLWVVADNLRRGAAFNALLLTEYLAKYII
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GINLAIVGSTGAVGQTILDILRENNLDFSLNNLKLLASENSAGTKITFGGKEITVEAAN
CEEEEEEECCCCHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCEEEECCEEEEEEECC
SSSFHDVDIAIFSAGSSVSKNLAPKAVESGAIVIDNSSAFRMDDKVPLVAAGVNYESLYE
CCCCCEEEEEEEECCCCHHCCCCCHHHCCCEEEEECCCCEEECCCCCEEEECCCHHHHHH
HEGIIANPNCSTIQMVCALKPILDHAGIKRIVVSTYQSVSGTGYQAMKELTEQSPKYLNN
CCCEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHCCC
EAIEKQIYPHQIAFNMLPHLDSFDENGDTKEELKMVNETKKIFQDENIGVTATTVRVPVF
HHHHHHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEE
IGHSEAVNIETKSKLSACDARQLLENFSEVEVIDDPFEAKYPTPIEIAGKDQVYVGRIRE
ECCCCEEEECHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEECCCCCEEEEHHHH
DLSIDNGLNLWVVADNLRRGAAFNALLLTEYLAKYII
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]