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The map label for this gene is trpS [H]

Identifier: 188585212

GI number: 188585212

Start: 603084

End: 604082

Strand: Reverse

Name: trpS [H]

Synonym: Nther_0574

Alternate gene names: 188585212

Gene position: 604082-603084 (Counterclockwise)

Preceding gene: 188585213

Following gene: 188585206

Centisome position: 19.08

GC content: 35.24

Gene sequence:

>999_bases
TTGACATCCAGTAATAAACCAATAATATTCAGTGGTGCTCAACCTTCTGGAAGTATGACTCTAGGTAATTATATCGGAGC
TGTACAAAACTGGAAGGAAATGGAGCAAGATTATCAATGTATCTTCTCCATCGTGGATCTTCACTCTTTAACAGTTCGTC
AAGATCCAAAACAGTTTAAAAAAACAGTTCTATCCTTCTTAGCTCAATATTTAGCATGTGGACTAGACCCAAATAATAGC
ATTATATTTTTCCAATCACATGTTAAAGAACATAGCGAGCTATCTTGGATACTTGGTTGTAATACCTATTTAGGAGAGCT
AAATAGAATGACTCAATTTAAGGAAAAGTCGGAGCGCCACGCAGATAATGTAAATGCTGGCTTATATACCTATCCTATTT
TAATGGCAGCAGATATACTACTATATCAAACTGACTTGGTCCCTGTGGGAGAAGATCAAAAACAACATTTAGAACTGGCC
AGGGATATTGCAGAAAGGTTTAATGGTGCTTATGGAAATGCATTCAAAGTACCAGAAATCCATATTCCAAAAATCGGGGC
TAGAATAATGAGCCTTCAGGAACCCGAGAAGAAAATGTCTAAATCCGATGAAAATGAAAAAGGTGTCTTATTTTTACTCG
ACGAAGAAAATGTCATCAGAAAGAAAATCAAAAGAGCAGTCACTGATAATGAAAACCAAATTGCTTATAATGATAGTCAA
CCCGGCATCAAAAATTTAATTACTATTTACTCAAAACTAAAACCTTGTACAGTAGAAGAAGTAGTAGAAGAGTATGCCGA
TCAAGGCTACGGAACTTTCAAAAAAGATGTGGCTGATTTAGTTGTGGATAGGTTACAACCTGTCAAGGATGAATACAATA
AATACATGGAAAACAAAGATTACTTAGAAGATGTTTATCATGAAGGAGCTAGAAAAGCCGCAGAAATTGCAGCAGATACC
ATGGAAAAAGTAAAAGATAAACTTGGACTAGTAAATTAA

Upstream 100 bases:

>100_bases
CATAGGATATCCTAATGAAACTAAACCTCAAAAGGAAATGTATGAAGAAGATAAGGTGACTGTTATCGAATAAGAGTTCA
ATAGAAAATGAGGTGATATT

Downstream 100 bases:

>100_bases
ATTGAAACTAGTCATAAAAGAGCCCGGATTTTTATCCGGGCTCTTTTTAATGTTAAATGTTGCTTTTAAATAGTTATTGA
TAGATATAAAATCTAATCTT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTSSNKPIIFSGAQPSGSMTLGNYIGAVQNWKEMEQDYQCIFSIVDLHSLTVRQDPKQFKKTVLSFLAQYLACGLDPNNS
IIFFQSHVKEHSELSWILGCNTYLGELNRMTQFKEKSERHADNVNAGLYTYPILMAADILLYQTDLVPVGEDQKQHLELA
RDIAERFNGAYGNAFKVPEIHIPKIGARIMSLQEPEKKMSKSDENEKGVLFLLDEENVIRKKIKRAVTDNENQIAYNDSQ
PGIKNLITIYSKLKPCTVEEVVEEYADQGYGTFKKDVADLVVDRLQPVKDEYNKYMENKDYLEDVYHEGARKAAEIAADT
MEKVKDKLGLVN

Sequences:

>Translated_332_residues
MTSSNKPIIFSGAQPSGSMTLGNYIGAVQNWKEMEQDYQCIFSIVDLHSLTVRQDPKQFKKTVLSFLAQYLACGLDPNNS
IIFFQSHVKEHSELSWILGCNTYLGELNRMTQFKEKSERHADNVNAGLYTYPILMAADILLYQTDLVPVGEDQKQHLELA
RDIAERFNGAYGNAFKVPEIHIPKIGARIMSLQEPEKKMSKSDENEKGVLFLLDEENVIRKKIKRAVTDNENQIAYNDSQ
PGIKNLITIYSKLKPCTVEEVVEEYADQGYGTFKKDVADLVVDRLQPVKDEYNKYMENKDYLEDVYHEGARKAAEIAADT
MEKVKDKLGLVN
>Mature_331_residues
TSSNKPIIFSGAQPSGSMTLGNYIGAVQNWKEMEQDYQCIFSIVDLHSLTVRQDPKQFKKTVLSFLAQYLACGLDPNNSI
IFFQSHVKEHSELSWILGCNTYLGELNRMTQFKEKSERHADNVNAGLYTYPILMAADILLYQTDLVPVGEDQKQHLELAR
DIAERFNGAYGNAFKVPEIHIPKIGARIMSLQEPEKKMSKSDENEKGVLFLLDEENVIRKKIKRAVTDNENQIAYNDSQP
GIKNLITIYSKLKPCTVEEVVEEYADQGYGTFKKDVADLVVDRLQPVKDEYNKYMENKDYLEDVYHEGARKAAEIAADTM
EKVKDKLGLVN

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=40.7294832826748, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=49.4318181818182, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1789786, Length=330, Percent_Identity=53.6363636363636, Blast_Score=370, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=33.1360946745562, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=33.1360946745562, Blast_Score=203, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320474, Length=343, Percent_Identity=39.6501457725948, Blast_Score=243, Evalue=4e-65,
Organism=Drosophila melanogaster, GI24666151, Length=325, Percent_Identity=40.9230769230769, Blast_Score=258, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37778; Mature: 37647

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00962 RIBOSOMAL_S2_1 ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSNKPIIFSGAQPSGSMTLGNYIGAVQNWKEMEQDYQCIFSIVDLHSLTVRQDPKQFK
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KTVLSFLAQYLACGLDPNNSIIFFQSHVKEHSELSWILGCNTYLGELNRMTQFKEKSERH
HHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHH
ADNVNAGLYTYPILMAADILLYQTDLVPVGEDQKQHLELARDIAERFNGAYGNAFKVPEI
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HIPKIGARIMSLQEPEKKMSKSDENEKGVLFLLDEENVIRKKIKRAVTDNENQIAYNDSQ
CCCHHHHHHHHCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCC
PGIKNLITIYSKLKPCTVEEVVEEYADQGYGTFKKDVADLVVDRLQPVKDEYNKYMENKD
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YLEDVYHEGARKAAEIAADTMEKVKDKLGLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSSNKPIIFSGAQPSGSMTLGNYIGAVQNWKEMEQDYQCIFSIVDLHSLTVRQDPKQFK
CCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KTVLSFLAQYLACGLDPNNSIIFFQSHVKEHSELSWILGCNTYLGELNRMTQFKEKSERH
HHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHH
ADNVNAGLYTYPILMAADILLYQTDLVPVGEDQKQHLELARDIAERFNGAYGNAFKVPEI
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
HIPKIGARIMSLQEPEKKMSKSDENEKGVLFLLDEENVIRKKIKRAVTDNENQIAYNDSQ
CCCHHHHHHHHCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEECCCC
PGIKNLITIYSKLKPCTVEEVVEEYADQGYGTFKKDVADLVVDRLQPVKDEYNKYMENKD
CCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YLEDVYHEGARKAAEIAADTMEKVKDKLGLVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]