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The map label for this gene is apbE [H]

Identifier: 188585149

GI number: 188585149

Start: 534614

End: 535675

Strand: Direct

Name: apbE [H]

Synonym: Nther_0510

Alternate gene names: 188585149

Gene position: 534614-535675 (Clockwise)

Preceding gene: 188585148

Following gene: 188585150

Centisome position: 16.89

GC content: 38.14

Gene sequence:

>1062_bases
ATGAATACAAACAAATCTCAATCTAGAGCCAAGCTAATTAAACTGTTAACTATATTTACAATACTGCTAGTTATGATGAC
TTCATTGATGGCTTGTGACTACGAAGTAGAAGAATATAGAGATACAGGAATCTATATGGACACCAGGGTTGATATTATTG
TTGAAGCTAGGAATGAGTCTATTGCCGATGAAGCAATTGATGCAGCTAAAGATGAAATCAATCGCCTAGAAAACAAAATG
TCAAGACATGTAGCTGGTAGTGAAATAGATGAAGTTAATCGCAATGCTGGTGAACAACCTATTCAAGTATCCCAAGAAAC
CTGGGAAGTAGTTGCTGAATCAATAGAATTAGGTGAACAGATGGACGGGTATTTTGATGTAACCATTGCTCCCCTGTTAA
CACTTTGGGGTTTTGGAGAAGATGAACATCACTTACCAAGTGATGAAGAAATTTCTGAATTACTTCCTCTTGTAAATCAT
AATGAAATTGAAATGGATGAGGAAAAACACACTATTTATTTACCTGACTCAGATATGAGGCTTGATTTAGGTGGAGCTGC
AAAGGGTTATATTGTAGATAGAGCCACCGAGGTTTTAGCAGAACATGATATCGAATCTGGTTTGGTCGATGCAGGTGGAG
ATATCAATACAGTTGGTCCAAAACACGATGACGAGCCTTGGAGGATAGGTGTTACTCACCCCAGAGATCGACAAAATTAC
TTTGCAGTTTTAGAATTGAATGGAGAAGCTGTGGACACTTCTGGGGATTATGAGCGGTATTTTGAAGAGGACGGGGTTAA
ATATCATCACATTCTCGATCCTTATACCGGTTACCCAACCGAAGGTATGATTAGTGCCACAGTTATGGCAGATAATGCTA
TTAGGGCGGATATTTTGTCAACTGGAGCTTTTGGACTGGGTTTAGAAGGAAGTTTAGAACTTTTTGAAGAACTGGATGAC
GTTGAAGCTATTATAGTAGATGATAACGGTGAATATCATATGACTTCTGGTTTGGATGGGATTGAAATTCCCGATCAATA
CAAAGATCAACAGTTAAAATAA

Upstream 100 bases:

>100_bases
CATAGAATATTTTAGTTGAAAATATTGGCAAAGATAACCCCGTAATTTTTTATCAATTTAAACGTTTTTAATGTTATGAT
ATCTCTAAGGAGGTTACTAT

Downstream 100 bases:

>100_bases
TATTATATTTCTAGTAAAGGAAGTTGTCCCATGAATAAAAACTTATCGAAGCTGATATATTTAGGATTACTGGTAACTTT
TGGCTTGGTATTGCACTTAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNTNKSQSRAKLIKLLTIFTILLVMMTSLMACDYEVEEYRDTGIYMDTRVDIIVEARNESIADEAIDAAKDEINRLENKM
SRHVAGSEIDEVNRNAGEQPIQVSQETWEVVAESIELGEQMDGYFDVTIAPLLTLWGFGEDEHHLPSDEEISELLPLVNH
NEIEMDEEKHTIYLPDSDMRLDLGGAAKGYIVDRATEVLAEHDIESGLVDAGGDINTVGPKHDDEPWRIGVTHPRDRQNY
FAVLELNGEAVDTSGDYERYFEEDGVKYHHILDPYTGYPTEGMISATVMADNAIRADILSTGAFGLGLEGSLELFEELDD
VEAIIVDDNGEYHMTSGLDGIEIPDQYKDQQLK

Sequences:

>Translated_353_residues
MNTNKSQSRAKLIKLLTIFTILLVMMTSLMACDYEVEEYRDTGIYMDTRVDIIVEARNESIADEAIDAAKDEINRLENKM
SRHVAGSEIDEVNRNAGEQPIQVSQETWEVVAESIELGEQMDGYFDVTIAPLLTLWGFGEDEHHLPSDEEISELLPLVNH
NEIEMDEEKHTIYLPDSDMRLDLGGAAKGYIVDRATEVLAEHDIESGLVDAGGDINTVGPKHDDEPWRIGVTHPRDRQNY
FAVLELNGEAVDTSGDYERYFEEDGVKYHHILDPYTGYPTEGMISATVMADNAIRADILSTGAFGLGLEGSLELFEELDD
VEAIIVDDNGEYHMTSGLDGIEIPDQYKDQQLK
>Mature_353_residues
MNTNKSQSRAKLIKLLTIFTILLVMMTSLMACDYEVEEYRDTGIYMDTRVDIIVEARNESIADEAIDAAKDEINRLENKM
SRHVAGSEIDEVNRNAGEQPIQVSQETWEVVAESIELGEQMDGYFDVTIAPLLTLWGFGEDEHHLPSDEEISELLPLVNH
NEIEMDEEKHTIYLPDSDMRLDLGGAAKGYIVDRATEVLAEHDIESGLVDAGGDINTVGPKHDDEPWRIGVTHPRDRQNY
FAVLELNGEAVDTSGDYERYFEEDGVKYHHILDPYTGYPTEGMISATVMADNAIRADILSTGAFGLGLEGSLELFEELDD
VEAIIVDDNGEYHMTSGLDGIEIPDQYKDQQLK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=290, Percent_Identity=30.3448275862069, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 39564; Mature: 39564

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNKSQSRAKLIKLLTIFTILLVMMTSLMACDYEVEEYRDTGIYMDTRVDIIVEARNES
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECEEEEEEEECCCH
IADEAIDAAKDEINRLENKMSRHVAGSEIDEVNRNAGEQPIQVSQETWEVVAESIELGEQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
MDGYFDVTIAPLLTLWGFGEDEHHLPSDEEISELLPLVNHNEIEMDEEKHTIYLPDSDMR
CCCEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCEEEECCCCCE
LDLGGAAKGYIVDRATEVLAEHDIESGLVDAGGDINTVGPKHDDEPWRIGVTHPRDRQNY
EECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCE
FAVLELNGEAVDTSGDYERYFEEDGVKYHHILDPYTGYPTEGMISATVMADNAIRADILS
EEEEEECCCEECCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHH
TGAFGLGLEGSLELFEELDDVEAIIVDDNGEYHMTSGLDGIEIPDQYKDQQLK
CCCCCCCCCCHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MNTNKSQSRAKLIKLLTIFTILLVMMTSLMACDYEVEEYRDTGIYMDTRVDIIVEARNES
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEECEEEEEEEECCCH
IADEAIDAAKDEINRLENKMSRHVAGSEIDEVNRNAGEQPIQVSQETWEVVAESIELGEQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
MDGYFDVTIAPLLTLWGFGEDEHHLPSDEEISELLPLVNHNEIEMDEEKHTIYLPDSDMR
CCCEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCEEEECCCCCE
LDLGGAAKGYIVDRATEVLAEHDIESGLVDAGGDINTVGPKHDDEPWRIGVTHPRDRQNY
EECCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCE
FAVLELNGEAVDTSGDYERYFEEDGVKYHHILDPYTGYPTEGMISATVMADNAIRADILS
EEEEEECCCEECCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHH
TGAFGLGLEGSLELFEELDDVEAIIVDDNGEYHMTSGLDGIEIPDQYKDQQLK
CCCCCCCCCCHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]