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The map label for this gene is grdC [H]

Identifier: 188585114

GI number: 188585114

Start: 503618

End: 505171

Strand: Direct

Name: grdC [H]

Synonym: Nther_0475

Alternate gene names: 188585114

Gene position: 503618-505171 (Clockwise)

Preceding gene: 188585113

Following gene: 188585115

Centisome position: 15.91

GC content: 38.67

Gene sequence:

>1554_bases
ATGGCGGCTTCCGTAGTTGGTGGTAACAGTTATATTCTTGTGCATGCTCCCAATACGATGAAATATCATGGTTCGACCCA
GCAATCAGATAGACACAAAAACCCAGAAAGTGATTATTTAAAAAATCTTCCTAATTACATGCGTTCTTTTGAAGATGCCG
TTAAATACCCCCCTAATCAAACTTACATTGGAAATATCTCTCCTGATGAACTAGCTCAAATAGAAAAACCTTGGTATCAA
AACCTTGATCAAGGTGATAGGTATAGTGACTGGGGAGAAATCATGCCAGAGGATGAGTTTTTCGGTTTAGTTCAAATTAG
TGATTCATTTGATTTGGTTAAATTGGAAGAAAATTTTGTTAACGAAATCAAACCTAAATTGGAAAAAAACCCTGTAATAA
CAAAAGACCATGTGGCGAAACTCTCTGGAACAAATAAAGATGAAATAAAGGAGATAGTTGATAATGGTAATGGAGAACCT
CTATATATAGATGATAATTTGGTGGGTTGTGTTAAATCTGCCCACGAAACCGACCAAAATTTAAATGCTCATGTTATGCT
TGAAAATTTAATGGCAAAAGCTTCAGGTTCTTTGGCATTACTGCACTTAGGGAATCAGCAAGGAGTAGATTTATCACAAA
CTGACTATGTAATGGAGGTCAGTGAAGAAGCATGTGGAGATGTTAACCAAAGAGGTGGAGGCAATTTTGCCAAGGCAATA
GCAGAAATAGCTGGTTGTGAAAATGCTACTGGTTCCGATGTAAGGACATTTTGTTCTGCTCCTGCCCATGCAATGATTAA
TGCAGCTGCACTAGTAGAAGCAGGAGTATATGAACAAGTAGCTATCGTAGCAGGTGGGGCAGTTGCAAAACTCGGAATGA
ATGGTAAGGATCATGTTAAGCAGGAAATGCCTGTGCTTGAAGACTGTTTAGGAGGATTGGCACTTTTAATAAGTAAAAAT
GATGGTCAAAACCCCATTATCAGAACTGATGCTATAGGTAAACACAATGTAGGTACAGGTTCTGCTCCTCAAGCTGTGAT
TTCCTCTTTAACAACAACTCCTTTAGAAAAATTGGGATTAACGGTTACAGATATAGATAAATATTCGGTAGAAATGCAAA
ACCCTGAACTGACTCAACCTGCCGGTGCCGGTGATGTACCAGCTTCTAATTATAAGATGATTGGTGCCTTAGGTGTTAAA
AAAGGTCAGTTAGAGAAGAAAGACATGATGAATTTTGTGCAGGAACGAGGCATGCCAGGTTTTGCACCTACTCAAGGACA
TATTCCTTCAGGTGTCCCCTTTGTTGGTCACGCTAGGCGTATGCTTGATAAGGGCGAGATAAGTAAAGCCATGATAATTG
GAAAAGGTAGTTTATTCTTAGGGCGACTGACTAACTTATTTGATGGAATTTCTTTTGTAATGGAACCTAATCAAGGTGAT
GTAGATGAGGAAGGAACAGTTTCAAAAGAGGAAATCAAACAAATAGTAGCTGGTTCGTTACGGGACTTAGCAGATTCTTT
ATCTGAAAATGCAGATAACGAGTCAGACAGTTAG

Upstream 100 bases:

>100_bases
TTTGCTATTTATAAGGGGATAAGTATCTATGCTTATCCCCTTTATTCGAGATAAAGGACAAGGACTTCTTAGTAATTAAG
ATGAGATGGAGGTGACTTAT

Downstream 100 bases:

>100_bases
GGGGTGAAATCTTGTCTCAAAAAGTTAAAAATCAATTATCAGAAGTTTTTCATGAACTTGCTGAAGCTTTAGAGTCCGGT
CAATACGGTAAAAAATCTAA

Product: Betaine reductase

Products: NA

Alternate protein names: Protein PC beta [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MAASVVGGNSYILVHAPNTMKYHGSTQQSDRHKNPESDYLKNLPNYMRSFEDAVKYPPNQTYIGNISPDELAQIEKPWYQ
NLDQGDRYSDWGEIMPEDEFFGLVQISDSFDLVKLEENFVNEIKPKLEKNPVITKDHVAKLSGTNKDEIKEIVDNGNGEP
LYIDDNLVGCVKSAHETDQNLNAHVMLENLMAKASGSLALLHLGNQQGVDLSQTDYVMEVSEEACGDVNQRGGGNFAKAI
AEIAGCENATGSDVRTFCSAPAHAMINAAALVEAGVYEQVAIVAGGAVAKLGMNGKDHVKQEMPVLEDCLGGLALLISKN
DGQNPIIRTDAIGKHNVGTGSAPQAVISSLTTTPLEKLGLTVTDIDKYSVEMQNPELTQPAGAGDVPASNYKMIGALGVK
KGQLEKKDMMNFVQERGMPGFAPTQGHIPSGVPFVGHARRMLDKGEISKAMIIGKGSLFLGRLTNLFDGISFVMEPNQGD
VDEEGTVSKEEIKQIVAGSLRDLADSLSENADNESDS

Sequences:

>Translated_517_residues
MAASVVGGNSYILVHAPNTMKYHGSTQQSDRHKNPESDYLKNLPNYMRSFEDAVKYPPNQTYIGNISPDELAQIEKPWYQ
NLDQGDRYSDWGEIMPEDEFFGLVQISDSFDLVKLEENFVNEIKPKLEKNPVITKDHVAKLSGTNKDEIKEIVDNGNGEP
LYIDDNLVGCVKSAHETDQNLNAHVMLENLMAKASGSLALLHLGNQQGVDLSQTDYVMEVSEEACGDVNQRGGGNFAKAI
AEIAGCENATGSDVRTFCSAPAHAMINAAALVEAGVYEQVAIVAGGAVAKLGMNGKDHVKQEMPVLEDCLGGLALLISKN
DGQNPIIRTDAIGKHNVGTGSAPQAVISSLTTTPLEKLGLTVTDIDKYSVEMQNPELTQPAGAGDVPASNYKMIGALGVK
KGQLEKKDMMNFVQERGMPGFAPTQGHIPSGVPFVGHARRMLDKGEISKAMIIGKGSLFLGRLTNLFDGISFVMEPNQGD
VDEEGTVSKEEIKQIVAGSLRDLADSLSENADNESDS
>Mature_516_residues
AASVVGGNSYILVHAPNTMKYHGSTQQSDRHKNPESDYLKNLPNYMRSFEDAVKYPPNQTYIGNISPDELAQIEKPWYQN
LDQGDRYSDWGEIMPEDEFFGLVQISDSFDLVKLEENFVNEIKPKLEKNPVITKDHVAKLSGTNKDEIKEIVDNGNGEPL
YIDDNLVGCVKSAHETDQNLNAHVMLENLMAKASGSLALLHLGNQQGVDLSQTDYVMEVSEEACGDVNQRGGGNFAKAIA
EIAGCENATGSDVRTFCSAPAHAMINAAALVEAGVYEQVAIVAGGAVAKLGMNGKDHVKQEMPVLEDCLGGLALLISKND
GQNPIIRTDAIGKHNVGTGSAPQAVISSLTTTPLEKLGLTVTDIDKYSVEMQNPELTQPAGAGDVPASNYKMIGALGVKK
GQLEKKDMMNFVQERGMPGFAPTQGHIPSGVPFVGHARRMLDKGEISKAMIIGKGSLFLGRLTNLFDGISFVMEPNQGDV
DEEGTVSKEEIKQIVAGSLRDLADSLSENADNESDS

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR017236
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 55725; Mature: 55594

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASVVGGNSYILVHAPNTMKYHGSTQQSDRHKNPESDYLKNLPNYMRSFEDAVKYPPNQ
CCCEEECCCEEEEEECCCCEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TYIGNISPDELAQIEKPWYQNLDQGDRYSDWGEIMPEDEFFGLVQISDSFDLVKLEENFV
CEECCCCHHHHHHHCCHHHHCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEHHHHHH
NEIKPKLEKNPVITKDHVAKLSGTNKDEIKEIVDNGNGEPLYIDDNLVGCVKSAHETDQN
HHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC
LNAHVMLENLMAKASGSLALLHLGNQQGVDLSQTDYVMEVSEEACGDVNQRGGGNFAKAI
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
AEIAGCENATGSDVRTFCSAPAHAMINAAALVEAGVYEQVAIVAGGAVAKLGMNGKDHVK
HHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHEECCHHEECCCCCHHHHH
QEMPVLEDCLGGLALLISKNDGQNPIIRTDAIGKHNVGTGSAPQAVISSLTTTPLEKLGL
HHCCHHHHHHCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHCC
TVTDIDKYSVEMQNPELTQPAGAGDVPASNYKMIGALGVKKGQLEKKDMMNFVQERGMPG
EEEECCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCC
FAPTQGHIPSGVPFVGHARRMLDKGEISKAMIIGKGSLFLGRLTNLFDGISFVMEPNQGD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCHHEEECCCCCC
VDEEGTVSKEEIKQIVAGSLRDLADSLSENADNESDS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AASVVGGNSYILVHAPNTMKYHGSTQQSDRHKNPESDYLKNLPNYMRSFEDAVKYPPNQ
CCEEECCCEEEEEECCCCEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
TYIGNISPDELAQIEKPWYQNLDQGDRYSDWGEIMPEDEFFGLVQISDSFDLVKLEENFV
CEECCCCHHHHHHHCCHHHHCCCCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEHHHHHH
NEIKPKLEKNPVITKDHVAKLSGTNKDEIKEIVDNGNGEPLYIDDNLVGCVKSAHETDQN
HHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCC
LNAHVMLENLMAKASGSLALLHLGNQQGVDLSQTDYVMEVSEEACGDVNQRGGGNFAKAI
CCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHH
AEIAGCENATGSDVRTFCSAPAHAMINAAALVEAGVYEQVAIVAGGAVAKLGMNGKDHVK
HHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHEECCHHEECCCCCHHHHH
QEMPVLEDCLGGLALLISKNDGQNPIIRTDAIGKHNVGTGSAPQAVISSLTTTPLEKLGL
HHCCHHHHHHCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHCC
TVTDIDKYSVEMQNPELTQPAGAGDVPASNYKMIGALGVKKGQLEKKDMMNFVQERGMPG
EEEECCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCC
FAPTQGHIPSGVPFVGHARRMLDKGEISKAMIIGKGSLFLGRLTNLFDGISFVMEPNQGD
CCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCHHEEECCCCCC
VDEEGTVSKEEIKQIVAGSLRDLADSLSENADNESDS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8223622; 1587286 [H]