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The map label for this gene is grdB [H]

Identifier: 188585113

GI number: 188585113

Start: 502191

End: 503498

Strand: Direct

Name: grdB [H]

Synonym: Nther_0474

Alternate gene names: 188585113

Gene position: 502191-503498 (Clockwise)

Preceding gene: 188585112

Following gene: 188585114

Centisome position: 15.86

GC content: 42.43

Gene sequence:

>1308_bases
GTGTCTAAAAAAATAGTCCATTATATAAACCAGTTCTTTGGCCAGATCGGTGGTGAGGAAAAGGCTGATACGGCGCCATT
TGTGAAGGAAGAACCTGTTGGACCTGGAACCGCTTTAAATGGTCAATTAGGAGATGAAGGTGAAATTGTTGCCACTATCA
TTTGTGGTGATGATTATTTCTCTTCTAATACCGAAGAGGCTAAAGAAGAAATTCGTAAAGTCTTACGGGATTATGACCCT
GATCTGGTAATTACTGGTCCAGCCTTTAATGCTGGGAGATATGGAACAGCAGCTGGCGGCGTTGCTGAACTGGCTGCAAC
TGAGTTTGAACTACCTGTAGTTTCAGGTATGTATCCGGAGAACCCCGGTGTTGATATGTACAAAAAGTATGCCTATATAA
TTGAAACATCAGATTCCGCTGCTGGCATGAGAAAAGCTGCTCCAGCCATAGCCGAATTATCTAAGAAAATTCTTAGAGGC
GAAGAACTGGGAACTCCTAAGGAAGAAGGTTATATCCCCCGAGGAATTCGCAAAAATGTCTTTTTTGAGGAGCGCGGTTC
CAAACGGGGTGTGGATATGCTGGTTAAAAAACTTAATCAAGAGAAGTTCGACACAGAATATCCCATGCCAGACTTTGATC
GGGTTGATCCTCAACCTGCTATAAAAGATATGGCAAATGCTAAAATTGCCTTGGTAACTTCAGGTGGAATTGTACCTAAA
GGAAATCCCGATGGAATTGAGTCATCCAGTGCTTCTAAATATGGAAAATATGAATTAAAAGGCATGGATACTTTGACAGC
AGAAAGCCATGAAACTGCACATGGTGGTTATGATCCAACTTATGCCAATGAAAATCCCAATAGAGTTCTTCCCTTGGATG
CGGCTAGGAAACTTGAACAAGAGGGTCGAATTGCTGAGTTACATGAATACTTCTATTCTACAGTAGGAAATGGAACTTCT
GTTGGAAATGCTCAACAATATGCGGCTGAAATAGCAGAGGATCTAAAGAATCACGGTGTGGATGCTGTTATACAGACTTC
CACCTGAGGCACATGTACTCGTTGCGGTGCAACGATGGTTAAAGAATACGAGCGTGCTGGTTTACCAGCGGTTCATGTGG
CCTCAATAGTGCCGATTTCAAAGACTGTGGGAGCTAATAGAATAGTTCCAGCTGTAGCTATTCCACATCCACTGGGCAAT
CCAAAACTAGACGAAGAGGAAGAATTTAAGGTGAGAAAGGATCTGGTTGATAAAGCACTCAAAGCTTTAGAAACCGAGCT
AGAAACTCAAACTGTTTTTGAGGACTAG

Upstream 100 bases:

>100_bases
AATGGTACTTGAAGTTGATGAAATTATACAAGAGGTCAAAGAGTATCGGGAAAAGTATTGTAAGTTCTTGTAATTTCCCC
TGAAGAAAGGAGGGACGAAG

Downstream 100 bases:

>100_bases
TGACAATTGATGGAATGTGTTTGCTATTTATAAGGGGATAAGTATCTATGCTTATCCCCTTTATTCGAGATAAAGGACAA
GGACTTCTTAGTAATTAAGA

Product: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSKKIVHYINQFFGQIGGEEKADTAPFVKEEPVGPGTALNGQLGDEGEIVATIICGDDYFSSNTEEAKEEIRKVLRDYDP
DLVITGPAFNAGRYGTAAGGVAELAATEFELPVVSGMYPENPGVDMYKKYAYIIETSDSAAGMRKAAPAIAELSKKILRG
EELGTPKEEGYIPRGIRKNVFFEERGSKRGVDMLVKKLNQEKFDTEYPMPDFDRVDPQPAIKDMANAKIALVTSGGIVPK
GNPDGIESSSASKYGKYELKGMDTLTAESHETAHGGYDPTYANENPNRVLPLDAARKLEQEGRIAELHEYFYSTVGNGTS
VGNAQQYAAEIAEDLKNHGVDAVIQTSTUGTCTRCGATMVKEYERAGLPAVHVASIVPISKTVGANRIVPAVAIPHPLGN
PKLDEEEEFKVRKDLVDKALKALETELETQTVFED

Sequences:

>Translated_435_residues
MSKKIVHYINQFFGQIGGEEKADTAPFVKEEPVGPGTALNGQLGDEGEIVATIICGDDYFSSNTEEAKEEIRKVLRDYDP
DLVITGPAFNAGRYGTAAGGVAELAATEFELPVVSGMYPENPGVDMYKKYAYIIETSDSAAGMRKAAPAIAELSKKILRG
EELGTPKEEGYIPRGIRKNVFFEERGSKRGVDMLVKKLNQEKFDTEYPMPDFDRVDPQPAIKDMANAKIALVTSGGIVPK
GNPDGIESSSASKYGKYELKGMDTLTAESHETAHGGYDPTYANENPNRVLPLDAARKLEQEGRIAELHEYFYSTVGNGTS
VGNAQQYAAEIAEDLKNHGVDAVIQTST*GTCTRCGATMVKEYERAGLPAVHVASIVPISKTVGANRIVPAVAIPHPLGN
PKLDEEEEFKVRKDLVDKALKALETELETQTVFED
>Mature_434_residues
SKKIVHYINQFFGQIGGEEKADTAPFVKEEPVGPGTALNGQLGDEGEIVATIICGDDYFSSNTEEAKEEIRKVLRDYDPD
LVITGPAFNAGRYGTAAGGVAELAATEFELPVVSGMYPENPGVDMYKKYAYIIETSDSAAGMRKAAPAIAELSKKILRGE
ELGTPKEEGYIPRGIRKNVFFEERGSKRGVDMLVKKLNQEKFDTEYPMPDFDRVDPQPAIKDMANAKIALVTSGGIVPKG
NPDGIESSSASKYGKYELKGMDTLTAESHETAHGGYDPTYANENPNRVLPLDAARKLEQEGRIAELHEYFYSTVGNGTSV
GNAQQYAAEIAEDLKNHGVDAVIQTST*GTCTRCGATMVKEYERAGLPAVHVASIVPISKTVGANRIVPAVAIPHPLGNP
KLDEEEEFKVRKDLVDKALKALETELETQTVFED

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 47085; Mature: 46954

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIVHYINQFFGQIGGEEKADTAPFVKEEPVGPGTALNGQLGDEGEIVATIICGDDYF
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
SSNTEEAKEEIRKVLRDYDPDLVITGPAFNAGRYGTAAGGVAELAATEFELPVVSGMYPE
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCHHCCCCCC
NPGVDMYKKYAYIIETSDSAAGMRKAAPAIAELSKKILRGEELGTPKEEGYIPRGIRKNV
CCCHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHCCCCCCCHHHCC
FFEERGSKRGVDMLVKKLNQEKFDTEYPMPDFDRVDPQPAIKDMANAKIALVTSGGIVPK
CHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCC
GNPDGIESSSASKYGKYELKGMDTLTAESHETAHGGYDPTYANENPNRVLPLDAARKLEQ
CCCCCCCCCCCCCCCCEEECCCCEECCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHH
EGRIAELHEYFYSTVGNGTSVGNAQQYAAEIAEDLKNHGVDAVIQTSTGTCTRCGATMVK
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
EYERAGLPAVHVASIVPISKTVGANRIVPAVAIPHPLGNPKLDEEEEFKVRKDLVDKALK
HHHHCCCCHHHHHHHCCHHHHCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ALETELETQTVFED
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SKKIVHYINQFFGQIGGEEKADTAPFVKEEPVGPGTALNGQLGDEGEIVATIICGDDYF
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
SSNTEEAKEEIRKVLRDYDPDLVITGPAFNAGRYGTAAGGVAELAATEFELPVVSGMYPE
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCHHCCCCCC
NPGVDMYKKYAYIIETSDSAAGMRKAAPAIAELSKKILRGEELGTPKEEGYIPRGIRKNV
CCCHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHCCCCCCCHHHCC
FFEERGSKRGVDMLVKKLNQEKFDTEYPMPDFDRVDPQPAIKDMANAKIALVTSGGIVPK
CHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCC
GNPDGIESSSASKYGKYELKGMDTLTAESHETAHGGYDPTYANENPNRVLPLDAARKLEQ
CCCCCCCCCCCCCCCCEEECCCCEECCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHH
EGRIAELHEYFYSTVGNGTSVGNAQQYAAEIAEDLKNHGVDAVIQTSTGTCTRCGATMVK
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
EYERAGLPAVHVASIVPISKTVGANRIVPAVAIPHPLGNPKLDEEEEFKVRKDLVDKALK
HHHHCCCCHHHHHHHCCHHHHCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHH
ALETELETQTVFED
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA