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The map label for this gene is yqgN [H]

Identifier: 188585075

GI number: 188585075

Start: 457876

End: 458481

Strand: Direct

Name: yqgN [H]

Synonym: Nther_0436

Alternate gene names: 188585075

Gene position: 457876-458481 (Clockwise)

Preceding gene: 188585074

Following gene: 188585076

Centisome position: 14.46

GC content: 33.5

Gene sequence:

>606_bases
TTGGGAAAAGAAGTTAAAGCAAAGTTAAGAAAACAAATGACTTCCAAAAGAAAAAGTATAACAGAAAAATTTCGCAGATC
TGCCAGTGATAAAATTATTAATACTTTAATAACTAAATTTTTAACTGATGACATAGCTATGATAATGACTTACATAGCTA
CAAAAGGAGAAGTAGACACTTACCCATTAATTAAATATGGACTAGACAAAGGTGTAGGTATCTGTGTTCCCAGAACTTTT
AAACAGACTAATGAGATGGAGCCTGTAAGAATAAATGATTTAGATAGAGATTTACAACCAGGTTCTTATGGCATTCCTGA
ACCTGTAACTGAGCTTACAAAATCAGTCTCTATTTCTGATATCGATATTGTAATAGTACCGGGAGTAGCCTTTGATGAGT
CTGGGTATCGCCTGGGTTTTGGTGGCGGATATTATGATAAATTTATTAATAGTTTAGCACCTAGCACAAAAAATATAGCC
CTGGCTTATGAATTTCAGATTTTTGAAAAACTTCCACGCGATTCATGGGATAAGCCAGTACATGCAATCATAACGGAAAA
ACAAACTCGATTTATTAATAAATCGTTTCCAGGGCAAAGAGAATAA

Upstream 100 bases:

>100_bases
TAGGGATTTTAAAACAGTGATGATGGGGAAGTCCTACTAAATATAATAAGGGCTTCCCCTTTTTTTAACTTTATACTATA
TTATTTGAAGGGGTGATAAT

Downstream 100 bases:

>100_bases
GTCAATTATTTTGTAGCATTAAAGTAAGGCTGTTTTAAAGTTGAATGTTGTTAGCTGTAAAATTTCAATTTCACTTATAA
AATTTTACAGTATCACGCCT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MGKEVKAKLRKQMTSKRKSITEKFRRSASDKIINTLITKFLTDDIAMIMTYIATKGEVDTYPLIKYGLDKGVGICVPRTF
KQTNEMEPVRINDLDRDLQPGSYGIPEPVTELTKSVSISDIDIVIVPGVAFDESGYRLGFGGGYYDKFINSLAPSTKNIA
LAYEFQIFEKLPRDSWDKPVHAIITEKQTRFINKSFPGQRE

Sequences:

>Translated_201_residues
MGKEVKAKLRKQMTSKRKSITEKFRRSASDKIINTLITKFLTDDIAMIMTYIATKGEVDTYPLIKYGLDKGVGICVPRTF
KQTNEMEPVRINDLDRDLQPGSYGIPEPVTELTKSVSISDIDIVIVPGVAFDESGYRLGFGGGYYDKFINSLAPSTKNIA
LAYEFQIFEKLPRDSWDKPVHAIITEKQTRFINKSFPGQRE
>Mature_200_residues
GKEVKAKLRKQMTSKRKSITEKFRRSASDKIINTLITKFLTDDIAMIMTYIATKGEVDTYPLIKYGLDKGVGICVPRTFK
QTNEMEPVRINDLDRDLQPGSYGIPEPVTELTKSVSISDIDIVIVPGVAFDESGYRLGFGGGYYDKFINSLAPSTKNIAL
AYEFQIFEKLPRDSWDKPVHAIITEKQTRFINKSFPGQRE

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789278, Length=179, Percent_Identity=27.3743016759777, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17510857, Length=196, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI161077430, Length=196, Percent_Identity=31.1224489795918, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22754; Mature: 22622

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKEVKAKLRKQMTSKRKSITEKFRRSASDKIINTLITKFLTDDIAMIMTYIATKGEVDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YPLIKYGLDKGVGICVPRTFKQTNEMEPVRINDLDRDLQPGSYGIPEPVTELTKSVSISD
CHHHHHCCCCCCEEECCCHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCC
IDIVIVPGVAFDESGYRLGFGGGYYDKFINSLAPSTKNIALAYEFQIFEKLPRDSWDKPV
CEEEEECCEEECCCCCEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCH
HAIITEKQTRFINKSFPGQRE
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GKEVKAKLRKQMTSKRKSITEKFRRSASDKIINTLITKFLTDDIAMIMTYIATKGEVDT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YPLIKYGLDKGVGICVPRTFKQTNEMEPVRINDLDRDLQPGSYGIPEPVTELTKSVSISD
CHHHHHCCCCCCEEECCCHHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCC
IDIVIVPGVAFDESGYRLGFGGGYYDKFINSLAPSTKNIALAYEFQIFEKLPRDSWDKPV
CEEEEECCEEECCCCCEEECCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCCH
HAIITEKQTRFINKSFPGQRE
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]