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The map label for this gene is fchA [H]

Identifier: 188585067

GI number: 188585067

Start: 448480

End: 449118

Strand: Direct

Name: fchA [H]

Synonym: Nther_0428

Alternate gene names: 188585067

Gene position: 448480-449118 (Clockwise)

Preceding gene: 188585065

Following gene: 188585069

Centisome position: 14.17

GC content: 38.34

Gene sequence:

>639_bases
ATGTCTTTAACTGAAAAGACAGTGGAGGAGTTTTTGGAGGTGCTATCAAGTAAAGAACCAGCACCGGGGGGAGGCAGTGT
TAGTGCCTTAGCTGGAAGCCTGGGAAGTTGTTTAACCACTATGGTAGGTAATTTAACAATTGGAAAAAAGAGATATCGAA
ATTTGGATGAAGCAGAGCAACGCGAATTAGACGAAAAATTTGAACAAGTTCAAAAAATAAAAACTAATTTGGATAATTTA
ATTGATAGGGATAAAGAAGCCTTTGATGAGGTGATGGCTGCTGTAAAAATGCCCAAAGAAACTGAAGAGGAAAAAGCCAA
GAGAAGGGAAGCTCTTCAAAAAGCAACTCAAACAGCTCTTGAGGTTCCCTTAGAAACTGCTAGGGAATGCTTGAAGGTCT
TGCAGTTACAGGAAGCCTTTGCTAGGAATGGGAATCCAAATGCAATAACTGATGTTGGTGTAGGAGCATTAATGGCTTAT
GCGGGTATTGAAGGTGCTATCTACAATGTAAAAATAAATTTGAGTGATTTAAAAGATGAAAATTACAAGAAGCAAGTGGA
GCAAGAGGTGGAAAAACTTCTTACTGAAGGTCAACAGTTGAAAGAAAAAATTCAGAGTATGGTCGACGAAAAAATGTAG

Upstream 100 bases:

>100_bases
GCTATAAAAATGTCCTTTTATTATTTAACATAAATTATGGACGTACCAAAATATGGTATGATAATTTATTATATAGAGCT
ATTAATAAGGAGGGATTTGG

Downstream 100 bases:

>100_bases
CTATCCTGATGAATACATGGTATGTTAATAAGGGAGCGAGCCAGTCTGCTCCCTTATTATTTATCTTTTTCTAAGTCATA
TAAAATTTTGTCTAAATACC

Product: Formiminotransferase-cyclodeaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSLTEKTVEEFLEVLSSKEPAPGGGSVSALAGSLGSCLTTMVGNLTIGKKRYRNLDEAEQRELDEKFEQVQKIKTNLDNL
IDRDKEAFDEVMAAVKMPKETEEEKAKRREALQKATQTALEVPLETARECLKVLQLQEAFARNGNPNAITDVGVGALMAY
AGIEGAIYNVKINLSDLKDENYKKQVEQEVEKLLTEGQQLKEKIQSMVDEKM

Sequences:

>Translated_212_residues
MSLTEKTVEEFLEVLSSKEPAPGGGSVSALAGSLGSCLTTMVGNLTIGKKRYRNLDEAEQRELDEKFEQVQKIKTNLDNL
IDRDKEAFDEVMAAVKMPKETEEEKAKRREALQKATQTALEVPLETARECLKVLQLQEAFARNGNPNAITDVGVGALMAY
AGIEGAIYNVKINLSDLKDENYKKQVEQEVEKLLTEGQQLKEKIQSMVDEKM
>Mature_211_residues
SLTEKTVEEFLEVLSSKEPAPGGGSVSALAGSLGSCLTTMVGNLTIGKKRYRNLDEAEQRELDEKFEQVQKIKTNLDNLI
DRDKEAFDEVMAAVKMPKETEEEKAKRREALQKATQTALEVPLETARECLKVLQLQEAFARNGNPNAITDVGVGALMAYA
GIEGAIYNVKINLSDLKDENYKKQVEQEVEKLLTEGQQLKEKIQSMVDEKM

Specific function: Required for both C1 and C2 metabolism [H]

COG id: COG3404

COG function: function code E; Methenyl tetrahydrofolate cyclohydrolase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cyclodeaminase/cyclohydrolase family [H]

Homologues:

Organism=Homo sapiens, GI46255035, Length=159, Percent_Identity=35.8490566037736, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI11140815, Length=159, Percent_Identity=35.8490566037736, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007044 [H]

Pfam domain/function: PF04961 FTCD_C [H]

EC number: =3.5.4.9 [H]

Molecular weight: Translated: 23597; Mature: 23466

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTEKTVEEFLEVLSSKEPAPGGGSVSALAGSLGSCLTTMVGNLTIGKKRYRNLDEAEQ
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHH
RELDEKFEQVQKIKTNLDNLIDRDKEAFDEVMAAVKMPKETEEEKAKRREALQKATQTAL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EVPLETARECLKVLQLQEAFARNGNPNAITDVGVGALMAYAGIEGAIYNVKINLSDLKDE
HCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCH
NYKKQVEQEVEKLLTEGQQLKEKIQSMVDEKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLTEKTVEEFLEVLSSKEPAPGGGSVSALAGSLGSCLTTMVGNLTIGKKRYRNLDEAEQ
CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHH
RELDEKFEQVQKIKTNLDNLIDRDKEAFDEVMAAVKMPKETEEEKAKRREALQKATQTAL
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EVPLETARECLKVLQLQEAFARNGNPNAITDVGVGALMAYAGIEGAIYNVKINLSDLKDE
HCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCH
NYKKQVEQEVEKLLTEGQQLKEKIQSMVDEKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961516; 10215859 [H]